{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,18]],"date-time":"2026-04-18T20:03:45Z","timestamp":1776542625461,"version":"3.51.2"},"reference-count":24,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2018,8,1]],"date-time":"2018-08-01T00:00:00Z","timestamp":1533081600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","mayoclinicproceedings.org","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Mayo Clinic Proceedings"],"published-print":{"date-parts":[[2018,8]]},"DOI":"10.1016\/j.mayocp.2017.12.011","type":"journal-article","created":{"date-parts":[[2018,3,21]],"date-time":"2018-03-21T05:34:41Z","timestamp":1521610481000},"page":"1018-1025","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":63,"title":["Outcomes of Radiofrequency Ablation Therapy for Large Benign Thyroid Nodules: A Mayo Clinic Case Series"],"prefix":"10.1016","volume":"93","author":[{"given":"Oksana","family":"Hamidi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew R.","family":"Callstrom","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert A.","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diana","family":"Dean","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. Regina","family":"Castro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John C.","family":"Morris","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marius N.","family":"Stan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.mayocp.2017.12.011_bib1","doi-asserted-by":"crossref","first-page":"226","DOI":"10.7326\/0003-4819-126-3-199702010-00009","article-title":"Thyroid incidentalomas: management approaches to nonpalpable nodules discovered incidentally on thyroid imaging","volume":"126","author":"Tan","year":"1997","journal-title":"Ann Intern Med"},{"issue":"8","key":"10.1016\/j.mayocp.2017.12.011_bib2","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1111\/j.1365-2362.2009.02162.x","article-title":"Very high prevalence of thyroid nodules detected by high frequency (13 MHz) ultrasound examination","volume":"39","author":"Guth","year":"2009","journal-title":"Eur J Clin Invest"},{"issue":"5","key":"10.1016\/j.mayocp.2017.12.011_bib3","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1007\/s00423-008-0366-7","article-title":"Complications to thyroid surgery: results as reported in a database from a multicenter audit comprising 3,660 patients","volume":"393","author":"Bergenfelz","year":"2008","journal-title":"Langenbeck Arch Surg"},{"issue":"1","key":"10.1016\/j.mayocp.2017.12.011_bib4","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1089\/thy.2015.0020","article-title":"2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer: the American Thyroid Association Guidelines Task Force on Thyroid Nodules and Differentiated Thyroid Cancer","volume":"26","author":"Haugen","year":"2016","journal-title":"Thyroid"},{"issue":"4","key":"10.1016\/j.mayocp.2017.12.011_bib5","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1089\/thy.2006.16.361","article-title":"Radiofrequency ablation of benign cold thyroid nodules: initial clinical experience","volume":"16","author":"Kim","year":"2006","journal-title":"Thyroid"},{"issue":"2","key":"10.1016\/j.mayocp.2017.12.011_bib6","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1210\/jc.2014-2186","article-title":"Prospective study of effectiveness of ultrasound-guided radiofrequency ablation versus control group in patients affected by benign thyroid nodules","volume":"100","author":"Cesareo","year":"2015","journal-title":"J\u00a0Clin Endocrinol Metab"},{"issue":"12","key":"10.1016\/j.mayocp.2017.12.011_bib7","doi-asserted-by":"crossref","first-page":"4439","DOI":"10.1210\/jc.2012-2251","article-title":"Thyroid nodules treated with percutaneous radiofrequency thermal ablation: a comparative study","volume":"97","author":"Faggiano","year":"2012","journal-title":"J\u00a0Clin Endocrinol Metab"},{"issue":"3","key":"10.1016\/j.mayocp.2017.12.011_bib8","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1089\/thy.2008.0202","article-title":"Thyroid nodules and related symptoms are stably controlled two years after radiofrequency thermal ablation","volume":"19","author":"Spiezia","year":"2009","journal-title":"Thyroid"},{"issue":"3","key":"10.1016\/j.mayocp.2017.12.011_bib9","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1148\/radiology.217.3.r00dc26633","article-title":"Tumor ablation with radio-frequency energy","volume":"217","author":"Gazelle","year":"2000","journal-title":"Radiology"},{"issue":"12","key":"10.1016\/j.mayocp.2017.12.011_bib10","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.1007\/s00268-004-7597-8","article-title":"Clinical evaluation of color Doppler imaging for the differential diagnosis of thyroid follicular lesions","volume":"28","author":"Fukunari","year":"2004","journal-title":"World J Surg"},{"issue":"11","key":"10.1016\/j.mayocp.2017.12.011_bib11","doi-asserted-by":"crossref","first-page":"3905","DOI":"10.1210\/jcem.83.11.5257","article-title":"Treatment of large cold benign thyroid nodules not eligible for surgery with percutaneous ethanol injection","volume":"83","author":"Zingrillo","year":"1998","journal-title":"J\u00a0Clin Endocrinol Metab"},{"issue":"6","key":"10.1016\/j.mayocp.2017.12.011_bib12","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1089\/thy.2007.0274","article-title":"Radiofrequency ablation for an autonomously functioning thyroid nodule","volume":"18","author":"Baek","year":"2008","journal-title":"Thyroid"},{"issue":"6","key":"10.1016\/j.mayocp.2017.12.011_bib13","doi-asserted-by":"crossref","first-page":"1244","DOI":"10.1007\/s00330-008-0880-6","article-title":"Radiofrequency ablation of benign thyroid nodules: safety and imaging follow-up in 236 patients","volume":"18","author":"Jeong","year":"2008","journal-title":"Eur Radiol"},{"issue":"9","key":"10.1016\/j.mayocp.2017.12.011_bib14","doi-asserted-by":"crossref","first-page":"1971","DOI":"10.1007\/s00268-009-0130-3","article-title":"Radiofrequency ablation for the treatment of autonomously functioning thyroid nodules","volume":"33","author":"Baek","year":"2009","journal-title":"World J Surg"},{"issue":"4","key":"10.1016\/j.mayocp.2017.12.011_bib15","doi-asserted-by":"crossref","first-page":"1044","DOI":"10.1007\/s00330-012-2671-3","article-title":"Radiofrequency ablation of benign non-functioning thyroid nodules: 4-year follow-up results for 111 patients","volume":"23","author":"Lim","year":"2013","journal-title":"Eur Radiol"},{"issue":"7","key":"10.1016\/j.mayocp.2017.12.011_bib16","doi-asserted-by":"crossref","first-page":"2243","DOI":"10.1210\/jc.2012-1063","article-title":"Risk of hypothyroidism following hemithyroidectomy: systematic review and meta-analysis of prognostic studies","volume":"97","author":"Verloop","year":"2012","journal-title":"J\u00a0Clin Endocrinol Metab"},{"issue":"4","key":"10.1016\/j.mayocp.2017.12.011_bib17","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1016\/j.surg.2009.06.026","article-title":"Thyroid hormone replacement after thyroid lobectomy","volume":"146","author":"Stoll","year":"2009","journal-title":"Surgery"},{"issue":"1","key":"10.1016\/j.mayocp.2017.12.011_bib18","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1097\/00005537-200201000-00022","article-title":"Advantages of recurrent laryngeal nerve identification in thyroidectomy and parathyroidectomy and the importance of preoperative and postoperative laryngoscopic examination in more than 1000 nerves at risk","volume":"112","author":"Steurer","year":"2002","journal-title":"Laryngoscope"},{"issue":"5","key":"10.1016\/j.mayocp.2017.12.011_bib19","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1097\/SLA.0b013e3182360118","article-title":"Total thyroidectomy for benign thyroid disease: is it really worthwhile?","volume":"254","author":"Barczynski","year":"2011","journal-title":"Ann Surg"},{"issue":"3","key":"10.1016\/j.mayocp.2017.12.011_bib20","first-page":"497","article-title":"Recurrent laryngeal nerve electrophysiologic monitoring in thyroid surgery: the standard of care?","volume":"19","author":"Witt","year":"2005","journal-title":"J\u00a0Voice"},{"issue":"7","key":"10.1016\/j.mayocp.2017.12.011_bib21","doi-asserted-by":"crossref","first-page":"1321","DOI":"10.3174\/ajnr.A4276","article-title":"Treatment of benign thyroid nodules: comparison of surgery with radiofrequency ablation","volume":"36","author":"Che","year":"2015","journal-title":"AJNR Am J Neuroradiol"},{"issue":"3","key":"10.1016\/j.mayocp.2017.12.011_bib22","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1089\/thy.2015.0407","article-title":"American Thyroid Association statement on remote-access thyroid surgery","volume":"26","author":"Berber","year":"2016","journal-title":"Thyroid"},{"issue":"3","key":"10.1016\/j.mayocp.2017.12.011_bib23","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1148\/radiol.12111300","article-title":"Symptomatic benign thyroid nodules: efficacy of additional radiofrequency ablation treatment session\u2014prospective randomized study","volume":"263","author":"Huh","year":"2012","journal-title":"Radiology"},{"issue":"8","key":"10.1016\/j.mayocp.2017.12.011_bib24","first-page":"905","article-title":"Radiofrequency ablation of benign thyroid nodules: depicting early sign of regrowth by calculating vital volume","volume":"33","author":"Sim","year":"2017","journal-title":"Int J Hyperthermia"}],"container-title":["Mayo Clinic Proceedings"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0025619617308881?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0025619617308881?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,8,1]],"date-time":"2018-08-01T14:31:04Z","timestamp":1533133864000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0025619617308881"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,8]]},"references-count":24,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2018,8]]}},"alternative-id":["S0025619617308881"],"URL":"https:\/\/doi.org\/10.1016\/j.mayocp.2017.12.011","relation":{},"ISSN":["0025-6196"],"issn-type":[{"value":"0025-6196","type":"print"}],"subject":[],"published":{"date-parts":[[2018,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Outcomes of Radiofrequency Ablation Therapy for Large Benign Thyroid Nodules: A Mayo Clinic Case Series","name":"articletitle","label":"Article Title"},{"value":"Mayo Clinic Proceedings","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.mayocp.2017.12.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Mayo Foundation for Medical Education and Research","name":"copyright","label":"Copyright"}]}}