{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T08:15:55Z","timestamp":1788250555324,"version":"build-2803163510"},"reference-count":20,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2019,8,1]],"date-time":"2019-08-01T00:00:00Z","timestamp":1564617600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"CTSA","award":["UL1 TR002377"],"award-info":[{"award-number":["UL1 TR002377"]}]},{"DOI":"10.13039\/100006108","name":"National Center for Advancing Translational Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.jp","mayoclinicproceedings.org","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Mayo Clinic Proceedings"],"published-print":{"date-parts":[[2019,8]]},"DOI":"10.1016\/j.mayocp.2019.01.040","type":"journal-article","created":{"date-parts":[[2019,7,3]],"date-time":"2019-07-03T17:44:20Z","timestamp":1562175860000},"page":"1509-1515","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":17,"title":["Role of Loop Diuretic Challenge in Stage 3 Acute Kidney Injury"],"prefix":"10.1016","volume":"94","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8399-7472","authenticated-orcid":false,"given":"Ankit","family":"Sakhuja","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ghassan","family":"Bandak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0996-1487","authenticated-orcid":false,"given":"Erin F.","family":"Barreto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1631-8238","authenticated-orcid":false,"given":"Saraschandra","family":"Vallabhajosyula","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6366-2859","authenticated-orcid":false,"given":"Jacob","family":"Jentzer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Albright","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2184-3683","authenticated-orcid":false,"given":"Kianoush B.","family":"Kashani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"7","key":"10.1016\/j.mayocp.2019.01.040_bib1","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1007\/s001340051281","article-title":"Acute renal failure in the ICU: risk factors and outcome evaluated by the SOFA score","volume":"26","author":"de Mendon\u00e7a","year":"2000","journal-title":"Intensive Care Med"},{"issue":"7","key":"10.1016\/j.mayocp.2019.01.040_bib2","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1001\/jama.294.7.813","article-title":"Beginning and Ending Supportive Therapy for the Kidney (BEST Kidney) Investigators. Acute renal failure in critically ill patients: a multinational, multicenter study","volume":"294","author":"Uchino","year":"2005","journal-title":"JAMA"},{"issue":"3","key":"10.1016\/j.mayocp.2019.01.040_bib3","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1007\/s00134-012-2796-5","article-title":"Incidence, risk factors and 90-day mortality of patients with acute kidney injury in Finnish intensive care units: the FINNAKI study","volume":"39","author":"Nisula","year":"2013","journal-title":"Intensive Care Med"},{"issue":"6","key":"10.1016\/j.mayocp.2019.01.040_bib4","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1038\/ki.2009.502","article-title":"Genetic and Inflammatory Markers of Sepsis (GenIMS) Investigators. Acute kidney injury in non-severe pneumonia is associated with an increased immune response and lower survival","volume":"77","author":"Murugan","year":"2010","journal-title":"Kidney Int"},{"issue":"2","key":"10.1016\/j.mayocp.2019.01.040_bib5","doi-asserted-by":"crossref","first-page":"187","DOI":"10.2215\/CJN.03200314","article-title":"AKI in low-risk versus high-risk patients in intensive care","volume":"10","author":"Sileanu","year":"2015","journal-title":"Clin J Am Soc Nephrol"},{"issue":"8","key":"10.1016\/j.mayocp.2019.01.040_bib6","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1164\/rccm.201502-0329OC","article-title":"Acute kidney injury requiring dialysis in severe sepsis","volume":"192","author":"Sakhuja","year":"2015","journal-title":"Am J Respir Crit Care Med"},{"issue":"2","key":"10.1016\/j.mayocp.2019.01.040_bib7","doi-asserted-by":"crossref","first-page":"R31","DOI":"10.1186\/cc5713","article-title":"Acute Kidney Injury Network. Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury","volume":"11","author":"Mehta","year":"2007","journal-title":"Crit Care"},{"issue":"2","key":"10.1016\/j.mayocp.2019.01.040_bib8","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1056\/NEJMoa1603017","article-title":"Initiation strategies for renal-replacement therapy in the intensive care unit","volume":"375","author":"Gaudry","year":"2016","journal-title":"N\u00a0Engl J Med"},{"issue":"20","key":"10.1016\/j.mayocp.2019.01.040_bib9","doi-asserted-by":"crossref","first-page":"2190","DOI":"10.1001\/jama.2016.5828","article-title":"Effect of early vs delayed initiation of renal replacement therapy on mortality in critically ill patients with acute kidney injury: the ELAIN Randomized clinical trial","volume":"315","author":"Zarbock","year":"2016","journal-title":"JAMA"},{"issue":"5","key":"10.1016\/j.mayocp.2019.01.040_bib10","doi-asserted-by":"crossref","first-page":"R207","DOI":"10.1186\/cc13015","article-title":"Development and standardization of a furosemide stress test to predict the severity of acute kidney injury","volume":"17","author":"Chawla","year":"2013","journal-title":"Crit Care"},{"issue":"4","key":"10.1016\/j.mayocp.2019.01.040_bib11","doi-asserted-by":"crossref","first-page":"1388","DOI":"10.1016\/j.athoracsur.2017.03.015","article-title":"Lack of furosemide responsiveness predicts acute kidney injury in infants after cardiac surgery","volume":"104","author":"Kakajiwala","year":"2017","journal-title":"Ann Thorac Surg"},{"issue":"1","key":"10.1016\/j.mayocp.2019.01.040_bib12","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1186\/s13613-018-0355-0","article-title":"Response to different furosemide doses predicts AKI progression in ICU patients with elevated plasma NGAL levels","volume":"8","author":"Matsuura","year":"2018","journal-title":"Ann Intensive Care"},{"issue":"1","key":"10.1016\/j.mayocp.2019.01.040_bib13","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1186\/s13054-018-2021-1","article-title":"Early versus standard initiation of renal replacement therapy in furosemide stress test non-responsive acute kidney injury patients (the FST trial)","volume":"22","author":"Lumlertgul","year":"2018","journal-title":"Crit Care"},{"issue":"5","key":"10.1016\/j.mayocp.2019.01.040_bib14","doi-asserted-by":"crossref","first-page":"988","DOI":"10.1016\/j.jcrc.2015.05.007","article-title":"Development and validation of electronic surveillance tool for acute kidney injury: a retrospective analysis","volume":"30","author":"Ahmed","year":"2015","journal-title":"J\u00a0Crit Care"},{"issue":"3","key":"10.1016\/j.mayocp.2019.01.040_bib15","doi-asserted-by":"crossref","first-page":"247","DOI":"10.4065\/mcp.2009.0479","article-title":"Informatics infrastructure for syndrome surveillance, decision support, reporting, and modeling of critical illness","volume":"85","author":"Herasevich","year":"2010","journal-title":"Mayo Clin Proc"},{"issue":"9","key":"10.1016\/j.mayocp.2019.01.040_bib16","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1016\/j.mayocp.2012.04.015","article-title":"Derivation and validation of automated electronic search strategies to extract Charlson comorbidities from electronic medical records","volume":"87","author":"Singh","year":"2012","journal-title":"Mayo Clin Proc"},{"issue":"1","key":"10.1016\/j.mayocp.2019.01.040_bib17","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1080\/1354750X.2017.1387934","article-title":"The prognostic value of the furosemide stress test in predicting delayed graft function following deceased donor kidney transplantation","volume":"23","author":"McMahon","year":"2018","journal-title":"Biomarkers"},{"issue":"2, pt 1","key":"10.1016\/j.mayocp.2019.01.040_bib18","doi-asserted-by":"crossref","first-page":"C177","DOI":"10.1152\/ajpcell.1987.253.2.C177","article-title":"Characteristics and functions of Na-K-Cl cotransport in epithelial tissues","volume":"253","author":"O'Grady","year":"1987","journal-title":"Am J Physiol"},{"issue":"5, pt 1","key":"10.1016\/j.mayocp.2019.01.040_bib19","doi-asserted-by":"crossref","first-page":"C799","DOI":"10.1152\/ajpcell.1986.250.5.C799","article-title":"Photoinactivation of sodium-potassium-chloride cotransport in LLC-PK1\/Cl 4 cells by bumetanide","volume":"250","author":"Amsler","year":"1986","journal-title":"Am J Physiol"},{"issue":"8","key":"10.1016\/j.mayocp.2019.01.040_bib20","doi-asserted-by":"crossref","first-page":"2023","DOI":"10.1681\/ASN.2014060535","article-title":"Furosemide stress test and biomarkers for the prediction of AKI severity","volume":"26","author":"Koyner","year":"2015","journal-title":"J\u00a0Am Soc Nephrol"}],"container-title":["Mayo Clinic Proceedings"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0025619619302101?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0025619619302101?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,9,22]],"date-time":"2019-09-22T13:38:51Z","timestamp":1569159531000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0025619619302101"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,8]]},"references-count":20,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2019,8]]}},"alternative-id":["S0025619619302101"],"URL":"https:\/\/doi.org\/10.1016\/j.mayocp.2019.01.040","relation":{},"ISSN":["0025-6196"],"issn-type":[{"value":"0025-6196","type":"print"}],"subject":[],"published":{"date-parts":[[2019,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Role of Loop Diuretic Challenge in Stage 3 Acute Kidney Injury","name":"articletitle","label":"Article Title"},{"value":"Mayo Clinic Proceedings","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.mayocp.2019.01.040","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Mayo Foundation for Medical Education and Research","name":"copyright","label":"Copyright"}]}}