{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T11:14:35Z","timestamp":1793272475903,"version":"4.5.0"},"reference-count":40,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2021,8,1]],"date-time":"2021-08-01T00:00:00Z","timestamp":1627776000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,8,1]],"date-time":"2021-08-01T00:00:00Z","timestamp":1627776000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","mayoclinicproceedings.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Mayo Clinic Proceedings"],"published-print":{"date-parts":[[2021,8]]},"DOI":"10.1016\/j.mayocp.2021.03.028","type":"journal-article","created":{"date-parts":[[2021,6,10]],"date-time":"2021-06-10T10:31:39Z","timestamp":1623321099000},"page":"2043-2057","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":24,"title":["Pituitary Tumor Surgery: Comparison of Endoscopic and Microscopic Techniques at a Single Center"],"prefix":"10.1016","volume":"96","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8087-7870","authenticated-orcid":false,"given":"Jamie J.","family":"Van Gompel","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John L.D.","family":"Atkinson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Garret","family":"Choby","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan L.","family":"Kasperbauer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janalee K.","family":"Stokken","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey R.","family":"Janus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erin K.","family":"O\u2019Brien","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason T.","family":"Little","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9332-2524","authenticated-orcid":false,"given":"Irina","family":"Bancos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline J.","family":"Davidge-Pitts","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6004-4844","authenticated-orcid":false,"given":"Dhanya","family":"Ramachandran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Justine S.","family":"Herndon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dana","family":"Erickson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1511-1198","authenticated-orcid":false,"given":"William L.","family":"Lanier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.mayocp.2021.03.028_bib1","first-page":"187","article-title":"[Hypophysectomy by trans-sphenoidal route]","volume":"6","author":"Guiot","year":"1963","journal-title":"Ann Radiol"},{"issue":"7","key":"10.1016\/j.mayocp.2021.03.028_bib2","doi-asserted-by":"crossref","first-page":"914","DOI":"10.1097\/00005537-199607000-00025","article-title":"Transnasal-transsphenoidal endoscopic surgery of the pituitary gland","volume":"106","author":"Carrau","year":"1996","journal-title":"Laryngoscope"},{"issue":"3","key":"10.1016\/j.mayocp.2021.03.028_bib3","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1093\/neuros\/nyx350","article-title":"Comparison of complications, trends, and costs in endoscopic vs microscopic pituitary surgery: analysis from a US health claims database","volume":"81","author":"Asemota","year":"2017","journal-title":"Neurosurgery"},{"issue":"6","key":"10.1016\/j.mayocp.2021.03.028_bib4","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1055\/s-0038-1639618","article-title":"Volumetry in the assessment of pituitary adenoma resection: endoscopy versus microscopy","volume":"79","author":"Wang","year":"2018","journal-title":"J\u00a0Neurol Surg B Skull Base"},{"key":"10.1016\/j.mayocp.2021.03.028_bib5","doi-asserted-by":"crossref","first-page":"e128","DOI":"10.1016\/j.wneu.2019.07.074","article-title":"Beyond the learning curve: comparison of microscopic and endoscopic incidences of internal carotid injury in a series of highly experienced operators","volume":"131","author":"Perry","year":"2019","journal-title":"World Neurosurg"},{"issue":"5","key":"10.1016\/j.mayocp.2021.03.028_bib6","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1007\/s11102-020-01054-y","article-title":"Trends in endoscopic and microscopic transsphenoidal surgery: a survey of the international society of pituitary surgeons between 2010 and 2020","volume":"23","author":"Khalafallah","year":"2020","journal-title":"Pituitary"},{"issue":"3","key":"10.1016\/j.mayocp.2021.03.028_bib7","first-page":"596","article-title":"Comparison of outcomes between a less experienced surgeon using a fully endoscopic technique and a very experienced surgeon using a microscopic transsphenoidal technique for pituitary adenoma","volume":"124","author":"Zaidi","year":"2016","journal-title":"J\u00a0Neurosurg"},{"key":"10.1016\/j.mayocp.2021.03.028_bib8","doi-asserted-by":"crossref","first-page":"e46","DOI":"10.1016\/j.wneu.2019.08.165","article-title":"Management of Cushing's disease: changing trend from microscopic to endoscopic surgery","volume":"134","author":"Bora","year":"2020","journal-title":"World Neurosurg"},{"key":"10.1016\/j.mayocp.2021.03.028_bib9","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1016\/j.wneu.2016.10.029","article-title":"Endoscopic endonasal versus microsurgical transsphenoidal approach for growth hormone-secreting pituitary adenomas-systematic review and meta-analysis","volume":"97","author":"Phan","year":"2017","journal-title":"World Neurosurg"},{"issue":"4","key":"10.1016\/j.mayocp.2021.03.028_bib10","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.4103\/0028-3886.266241","article-title":"Endoscopic versus microscopic pituitary adenoma surgery: a single-center study","volume":"67","author":"Pablo","year":"2019","journal-title":"Neurol India"},{"key":"10.1016\/j.mayocp.2021.03.028_bib11","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1136\/jnnp-2012-304583","article-title":"Endoscopic versus microscopic pituitary surgery","volume":"84","author":"Oldfield","year":"2013","journal-title":"J\u00a0Neurol Neurosurg Psychiatry"},{"key":"10.1016\/j.mayocp.2021.03.028_bib12","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/j.wneu.2016.09.120","article-title":"Endoscopic versus microscopic transsphenoidal approach for pituitary adenomas: comparison of outcomes during the transition of methods of a single surgeon","volume":"97","author":"Eseonu","year":"2017","journal-title":"World Neurosurg"},{"issue":"7","key":"10.1016\/j.mayocp.2021.03.028_bib13","doi-asserted-by":"crossref","first-page":"e648","DOI":"10.1097\/SCS.0000000000003000","article-title":"Endoscopic versus microscopic transsphenoidal surgery for pituitary tumors","volume":"27","author":"Guo-Dong","year":"2016","journal-title":"J\u00a0Craniofac Surg"},{"key":"10.1016\/j.mayocp.2021.03.028_bib14","author":"Goshtasbi"},{"issue":"3-4","key":"10.1016\/j.mayocp.2021.03.028_bib15","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1159\/000095534","article-title":"The endoscopic versus the traditional approach in pituitary surgery","volume":"83","author":"Frank","year":"2006","journal-title":"Neuroendocrinology"},{"key":"10.1016\/j.mayocp.2021.03.028_bib16","doi-asserted-by":"crossref","first-page":"3190","DOI":"10.1210\/jc.2013-1036","article-title":"Endoscopic vs microsurgical transsphenoidal surgery for acromegaly: outcomes in a concurrent series of patients using modern criteria for remission","volume":"98","author":"Starke","year":"2013","journal-title":"J\u00a0Clin Endocrinol Metab"},{"issue":"5","key":"10.1016\/j.mayocp.2021.03.028_bib17","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1007\/s11102-018-0893-3","article-title":"Endoscopic vs. microscopic transsphenoidal surgery for Cushing's disease: a systematic review and meta-analysis","volume":"21","author":"Broersen","year":"2018","journal-title":"Pituitary"},{"issue":"4","key":"10.1016\/j.mayocp.2021.03.028_bib18","doi-asserted-by":"crossref","first-page":"E11","DOI":"10.3171\/2011.1.FOCUS10308","article-title":"Evidence of improved surgical outcome following endoscopy for nonfunctioning pituitary adenoma removal","volume":"30","author":"Messerer","year":"2011","journal-title":"Neurosurg Focus"},{"issue":"5","key":"10.1016\/j.mayocp.2021.03.028_bib19","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1007\/s00701-017-3438-z","article-title":"Gross total resection of pituitary adenomas after endoscopic vs. microscopic transsphenoidal surgery: a meta-analysis","volume":"160","author":"Almutairi","year":"2018","journal-title":"Acta Neurochir (Wien)"},{"issue":"1","key":"10.1016\/j.mayocp.2021.03.028_bib20","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1097\/MOO.0b013e328334db5b","article-title":"Microscopic versus endoscopic transnasal pituitary surgery","volume":"18","author":"Schaberg","year":"2010","journal-title":"Curr Opin Otolaryngol Head Neck Surg"},{"key":"10.1016\/j.mayocp.2021.03.028_bib21","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.ejim.2017.03.023","article-title":"Non-functioning pituitary adenoma underwent surgery: a multicenter retrospective study over the last four decades (1977-2015)","volume":"41","author":"Iglesias","year":"2017","journal-title":"Eur J Intern Med"},{"issue":"4","key":"10.1016\/j.mayocp.2021.03.028_bib22","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1097\/SCS.0000000000002684","article-title":"Outcomes and complications of endoscopic versus microscopic transsphenoidal surgery in pituitary adenoma","volume":"27","author":"Guvenc","year":"2016","journal-title":"J\u00a0Craniofac Surg"},{"issue":"7","key":"10.1016\/j.mayocp.2021.03.028_bib23","doi-asserted-by":"crossref","first-page":"554","DOI":"10.29271\/jcpsp.2018.07.554","article-title":"Postoperative complications of endoscopic versus microscopic transsphenoidal pituitary surgery: a meta-analysis","volume":"28","author":"Fang","year":"2018","journal-title":"J\u00a0Coll Physicians Surg Pak"},{"issue":"2","key":"10.1016\/j.mayocp.2021.03.028_bib24","first-page":"175","article-title":"Purely endoscopic transsphenoidal surgery versus traditional microsurgery for resection of pituitary adenomas: systematic review","volume":"40","author":"Strychowsky","year":"2011","journal-title":"J\u00a0Otolaryngol Head Neck Surg"},{"issue":"2","key":"10.1016\/j.mayocp.2021.03.028_bib25","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1007\/s11060-016-2124-y","article-title":"Resection of pituitary tumors: endoscopic versus microscopic","volume":"130","author":"Singh","year":"2016","journal-title":"J\u00a0Neurooncol"},{"issue":"3","key":"10.1016\/j.mayocp.2021.03.028_bib26","first-page":"511","article-title":"Retrospective analysis of a concurrent series of microscopic versus endoscopic transsphenoidal surgeries for Knosp grades 0-2 nonfunctioning pituitary macroadenomas at a single institution","volume":"121","author":"Dallapiazza","year":"2014","journal-title":"J\u00a0Neurosurg"},{"issue":"8","key":"10.1016\/j.mayocp.2021.03.028_bib27","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1136\/jnnp-2012-303194","article-title":"Short-term outcome of endoscopic versus microscopic pituitary adenoma surgery: a systematic review and meta-analysis","volume":"84","author":"Ammirati","year":"2013","journal-title":"J\u00a0Neurol Neurosurg Psychiatry"},{"issue":"3","key":"10.1016\/j.mayocp.2021.03.028_bib28","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1007\/s00701-013-1959-7","article-title":"Surgical complications after transsphenoidal microscopic and endoscopic surgery for pituitary adenoma: a consecutive series of 506 procedures","volume":"156","author":"Halvorsen","year":"2014","journal-title":"Acta Neurochir (Wien)"},{"issue":"4","key":"10.1016\/j.mayocp.2021.03.028_bib29","first-page":"1043","article-title":"Results of a prospective multicenter controlled study comparing surgical outcomes of microscopic versus fully endoscopic transsphenoidal surgery for nonfunctioning pituitary adenomas: the Transsphenoidal Extent of Resection (TRANSSPHER) Study","volume":"132","author":"Little","year":"2020","journal-title":"J\u00a0Neurosurg"},{"issue":"4","key":"10.1016\/j.mayocp.2021.03.028_bib30","first-page":"610","article-title":"Pituitary adenomas with invasion of the cavernous sinus space: a magnetic resonance imaging classification compared with surgical findings","volume":"33","author":"Knosp","year":"1993","journal-title":"Neurosurgery"},{"issue":"7","key":"10.1016\/j.mayocp.2021.03.028_bib31","doi-asserted-by":"crossref","first-page":"661","DOI":"10.4065\/74.7.661","article-title":"Preliminary comparison of the endoscopic transnasal vs the sublabial transseptal approach for clinically nonfunctioning pituitary macroadenomas","volume":"74","author":"Sheehan","year":"1999","journal-title":"Mayo Clin Proc"},{"issue":"5","key":"10.1016\/j.mayocp.2021.03.028_bib32","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1055\/s-0031-1280682","article-title":"Endoscopic endonasal infrasellar approach to the sellar and suprasellar regions: technical note","volume":"21","author":"Paluzzi","year":"2011","journal-title":"Skull Base"},{"issue":"4","key":"10.1016\/j.mayocp.2021.03.028_bib33","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1007\/s11102-013-0502-4","article-title":"Endoscopic endonasal approach for pituitary adenomas: a series of 555 patients","volume":"17","author":"Paluzzi","year":"2014","journal-title":"Pituitary"},{"issue":"2","key":"10.1016\/j.mayocp.2021.03.028_bib34","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1002\/alr.22468","article-title":"The effect of topical epinephrine 1:1000 with and without infiltration of 1% lidocaine with epinephrine 1:100,000 on endoscopic surgical field visualization: a double-blind randomized controlled study","volume":"10","author":"Tangbumrungtham","year":"2020","journal-title":"Int Forum Allergy Rhinol"},{"issue":"6","key":"10.1016\/j.mayocp.2021.03.028_bib35","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1055\/s-0035-1554905","article-title":"The olfactory strip and its preservation in endoscopic pituitary surgery maintains smell and sinonasal function","volume":"76","author":"Harvey","year":"2015","journal-title":"J\u00a0Neurol Surg B Skull Base"},{"issue":"2","key":"10.1016\/j.mayocp.2021.03.028_bib36","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1177\/0194599814561431","article-title":"Delayed nasoseptal flaps for endoscopic skull base reconstruction: proof of concept and evaluation of outcomes","volume":"152","author":"Choby","year":"2015","journal-title":"Otolaryngol Head Neck Surg"},{"issue":"4","key":"10.1016\/j.mayocp.2021.03.028_bib37","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1055\/s-0038-1675588","article-title":"Timing of postoperative CSF leak after endoscopic skull base surgery in patients with obstructive sleep apnea","volume":"80","author":"Zimmermann","year":"2019","journal-title":"J\u00a0Neurol Surg B Skull Base"},{"key":"10.1016\/j.mayocp.2021.03.028_bib38","doi-asserted-by":"crossref","first-page":"e733","DOI":"10.1016\/j.wneu.2018.05.077","article-title":"Beyond gross total and subtotal: does volumetric resection matter in nonfunctioning pituitary macroadenomas?","volume":"116","author":"Hughes","year":"2018","journal-title":"World Neurosurg"},{"issue":"2","key":"10.1016\/j.mayocp.2021.03.028_bib39","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1080\/02688697.2018.1429569","article-title":"Clinical outcomes of endoscopic versus microscopic trans-sphenoidal surgery for large pituitary adenoma","volume":"32","author":"Akbari","year":"2018","journal-title":"Br J Neurosurg"},{"issue":"1","key":"10.1016\/j.mayocp.2021.03.028_bib40","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1093\/ons\/opz085","article-title":"Evaluation of surgical resection goal and its relationship to extent of resection and patient outcomes in a multicenter prospective study of patients with surgically treated, nonfunctioning pituitary adenomas: a case series","volume":"18","author":"Little","year":"2020","journal-title":"Oper Neurosurg (Hagerstown)"}],"container-title":["Mayo Clinic Proceedings"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0025619621002548?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0025619621002548?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,21]],"date-time":"2025-09-21T01:36:10Z","timestamp":1758418570000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0025619621002548"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,8]]},"references-count":40,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2021,8]]}},"alternative-id":["S0025619621002548"],"URL":"https:\/\/doi.org\/10.1016\/j.mayocp.2021.03.028","relation":{},"ISSN":["0025-6196"],"issn-type":[{"value":"0025-6196","type":"print"}],"subject":[],"published":{"date-parts":[[2021,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Pituitary Tumor Surgery: Comparison of Endoscopic and Microscopic Techniques at a Single Center","name":"articletitle","label":"Article Title"},{"value":"Mayo Clinic Proceedings","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.mayocp.2021.03.028","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Mayo Foundation for Medical Education and Research","name":"copyright","label":"Copyright"}]}}