{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T10:34:11Z","timestamp":1788431651788,"version":"build-2803163510"},"reference-count":34,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"am","delay-in-days":365,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","mayoclinicproceedings.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Mayo Clinic Proceedings"],"published-print":{"date-parts":[[2022,7]]},"DOI":"10.1016\/j.mayocp.2022.01.027","type":"journal-article","created":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T06:11:11Z","timestamp":1656655871000},"page":"1305-1317","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"title":["Efficacy of Prolonged Antibiotic Therapy for Renal Cyst Infections in Polycystic Kidney Disease"],"prefix":"10.1016","volume":"97","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5690-7424","authenticated-orcid":false,"given":"Julien","family":"Dang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Scemla","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charlotte","family":"Loheac","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anis","family":"Chaba","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank","family":"Bienaim\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dominique","family":"Joly","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christophe","family":"Legendre","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bertrand","family":"Knebelmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline","family":"Charlier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"10","key":"10.1016\/j.mayocp.2022.01.027_bib1","doi-asserted-by":"crossref","first-page":"2593","DOI":"10.1681\/ASN.2018050493","article-title":"Prevalence estimates of polycystic kidney and liver disease by population sequencing","volume":"29","author":"Lanktree","year":"2018","journal-title":"J\u00a0Am Soc Nephrol"},{"issue":"14","key":"10.1016\/j.mayocp.2022.01.027_bib2","doi-asserted-by":"crossref","first-page":"1477","DOI":"10.1056\/NEJMcp0804458","article-title":"Autosomal dominant polycystic kidney disease","volume":"359","author":"Grantham","year":"2008","journal-title":"N\u00a0Engl J Med"},{"issue":"3","key":"10.1016\/j.mayocp.2022.01.027_bib3","doi-asserted-by":"crossref","first-page":"942","DOI":"10.1681\/ASN.2015010016","article-title":"The PROPKD score: a new algorithm to predict renal survival in autosomal dominant polycystic kidney disease","volume":"27","author":"Cornec\u2013Le Gall","year":"2016","journal-title":"J\u00a0Am Soc Nephrol"},{"issue":"1","key":"10.1016\/j.mayocp.2022.01.027_bib4","first-page":"144","article-title":"Management of renal cyst infection in patients with autosomal dominant polycystic kidney disease: a systematic review","volume":"32","author":"Lantinga","year":"2017","journal-title":"Nephrol Dial Transplant"},{"issue":"7","key":"10.1016\/j.mayocp.2022.01.027_bib5","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.2215\/CJN.01870309","article-title":"Cyst infections in patients with autosomal dominant polycystic kidney disease","volume":"4","author":"Sall\u00e9e","year":"2009","journal-title":"Clin J Am Soc Nephrol"},{"issue":"5","key":"10.1016\/j.mayocp.2022.01.027_bib6","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1093\/ndt\/gfu227","article-title":"Diagnostic criteria in renal and hepatic cyst infection","volume":"30","author":"Lantinga","year":"2015","journal-title":"Nephrol Dial Transplant"},{"issue":"1","key":"10.1016\/j.mayocp.2022.01.027_bib7","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1186\/s12882-016-0381-9","article-title":"Intracystic magnetic resonance imaging in patients with autosomal dominant polycystic kidney disease: features of severe cyst infection in a case-control study","volume":"17","author":"Suwabe","year":"2016","journal-title":"BMC Nephrol"},{"issue":"10","key":"10.1016\/j.mayocp.2022.01.027_bib8","doi-asserted-by":"crossref","first-page":"3746","DOI":"10.1093\/ndt\/gfs352","article-title":"Diagnosis of cyst infection in patients with autosomal dominant polycystic kidney disease: attributes and limitations of the current modalities","volume":"27","author":"Jouret","year":"2012","journal-title":"Nephrol Dial Transplant"},{"issue":"12","key":"10.1016\/j.mayocp.2022.01.027_bib9","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0207880","article-title":"Infected cyst in patients with autosomal dominant polycystic kidney disease: analysis of computed tomographic and ultrasonographic imaging features","volume":"13","author":"Oh","year":"2018","journal-title":"PLoS One"},{"issue":"1","key":"10.1016\/j.mayocp.2022.01.027_bib10","first-page":"F3","article-title":"Polycystic kidney disease: a predominance of giant nephrons","volume":"244","author":"Grantham","year":"1983","journal-title":"Am J Physiol"},{"issue":"1-6","key":"10.1016\/j.mayocp.2022.01.027_bib11","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1111\/j.0954-6820.1977.tb16837.x","article-title":"Fluid turnover in renal cysts","volume":"202","author":"Jacobsson","year":"1977","journal-title":"Acta Med Scand"},{"issue":"6","key":"10.1016\/j.mayocp.2022.01.027_bib12","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1016\/S0272-6386(85)80102-5","article-title":"Cyst fluid antibiotic concentrations in autosomal-dominant polycystic kidney disease","volume":"6","author":"Bennett","year":"1985","journal-title":"Am J Kidney Dis"},{"issue":"4","key":"10.1016\/j.mayocp.2022.01.027_bib13","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1038\/ki.1981.170","article-title":"Cyst fluid antibiotic concentrations in polycystic kidney disease: differences between proximal and distal cysts","volume":"20","author":"Muther","year":"1981","journal-title":"Kidney Int"},{"issue":"11","key":"10.1016\/j.mayocp.2022.01.027_bib14","first-page":"895","article-title":"Penetration of piperacillin into renal cysts","volume":"12","author":"Bonadio","year":"1986","journal-title":"Drugs Exp Clin Res"},{"issue":"10174","key":"10.1016\/j.mayocp.2022.01.027_bib15","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1016\/S0140-6736(18)32782-X","article-title":"Autosomal dominant polycystic kidney disease","volume":"393","author":"Cornec\u2013Le Gall","year":"2019","journal-title":"Lancet"},{"issue":"7","key":"10.1016\/j.mayocp.2022.01.027_bib16","doi-asserted-by":"crossref","first-page":"1644","DOI":"10.2215\/CJN.06900810","article-title":"Positron-emission computed tomography in cyst infection diagnosis in patients with autosomal dominant polycystic kidney disease","volume":"6","author":"Jouret","year":"2011","journal-title":"Clin J Am Soc Nephrol"},{"issue":"5","key":"10.1016\/j.mayocp.2022.01.027_bib17","first-page":"226","article-title":"Clinical predictors of escalating care in hepatic and renal cyst infection in autosomal dominant polycystic kidney and liver disease","volume":"76","author":"Lantinga","year":"2018","journal-title":"Neth J Med"},{"issue":"10","key":"10.1016\/j.mayocp.2022.01.027_bib18","doi-asserted-by":"crossref","first-page":"O721","DOI":"10.1111\/1469-0691.12500","article-title":"Clinical characteristics predicting early clinical failure after 72 h of antibiotic treatment in women with community-onset acute pyelonephritis: a prospective multicentre study","volume":"20","author":"Wie","year":"2014","journal-title":"Clin Microbiol Infect"},{"issue":"10","key":"10.1016\/j.mayocp.2022.01.027_bib19","doi-asserted-by":"crossref","first-page":"1965","DOI":"10.1681\/ASN.V9101965","article-title":"Composition of fluid in twelve cysts of a polycystic kidney. 1969","volume":"9","author":"Gardner","year":"1998","journal-title":"J\u00a0Am Soc Nephrol"},{"issue":"3","key":"10.1016\/j.mayocp.2022.01.027_bib20","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1038\/ki.1980.148","article-title":"Macropuncture study of polycystic disease in adult human kidneys","volume":"18","author":"Huseman","year":"1980","journal-title":"Kidney Int"},{"issue":"3","key":"10.1016\/j.mayocp.2022.01.027_bib21","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1038\/ki.1980.43","article-title":"Ultrastructure and function of cysts from human adult polycystic kidneys","volume":"17","author":"Cuppage","year":"1980","journal-title":"Kidney Int"},{"key":"10.1016\/j.mayocp.2022.01.027_bib22","doi-asserted-by":"crossref","unstructured":"Jouret F, Hogan MC, Chebib FT. A practical guide for the management of acute abdominal pain with fever in patients with autosomal dominant polycystic kidney disease. Nephrol Dial Transplant. Published online February 11, 2021. https:\/\/doi.org\/10.1093\/ndt\/gfab040.","DOI":"10.1093\/ndt\/gfab040"},{"issue":"6","key":"10.1016\/j.mayocp.2022.01.027_bib23","doi-asserted-by":"crossref","first-page":"884","DOI":"10.1038\/ki.1987.290","article-title":"Trimethoprim-sulfamethoxazole in cyst fluid from autosomal dominant polycystic kidneys","volume":"32","author":"Elzinga","year":"1987","journal-title":"Kidney Int"},{"issue":"6","key":"10.1016\/j.mayocp.2022.01.027_bib24","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1128\/AAC.32.6.844","article-title":"Ciprofloxacin activity in cyst fluid from polycystic kidneys","volume":"32","author":"Elzinga","year":"1988","journal-title":"Antimicrob Agents Chemother"},{"issue":"1","key":"10.1016\/j.mayocp.2022.01.027_bib25","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1159\/000186523","article-title":"Biochemical and pharmacodynamic studies of simple renal cyst fluids in relation to infection","volume":"59","author":"Ohkawa","year":"1991","journal-title":"Nephron"},{"issue":"1","key":"10.1016\/j.mayocp.2022.01.027_bib26","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1186\/s12882-018-1067-2","article-title":"Cyst infection in autosomal dominant polycystic kidney disease: penetration of meropenem into infected cysts","volume":"19","author":"Hamanoue","year":"2018","journal-title":"BMC Nephrol"},{"issue":"1","key":"10.1016\/j.mayocp.2022.01.027_bib27","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1053\/j.ajkd.2005.09.021","article-title":"Levofloxacin penetration into a renal cyst in a patient with autosomal dominant polycystic kidney disease","volume":"47","author":"Hiyama","year":"2006","journal-title":"Am J Kidney Dis"},{"issue":"12","key":"10.1016\/j.mayocp.2022.01.027_bib28","doi-asserted-by":"crossref","first-page":"1228.e23","DOI":"10.1016\/j.amjmed.2012.05.027","article-title":"Impact of age, sex, obesity, and steroid use on quinolone-associated tendon disorders","volume":"125","author":"Wise","year":"2012","journal-title":"Am J Med"},{"issue":"11","key":"10.1016\/j.mayocp.2022.01.027_bib29","doi-asserted-by":"crossref","first-page":"1839","DOI":"10.1001\/jamainternmed.2015.5389","article-title":"Risk of aortic dissection and aortic aneurysm in patients taking oral fluoroquinolone","volume":"175","author":"Lee","year":"2015","journal-title":"JAMA Intern Med"},{"issue":"21","key":"10.1016\/j.mayocp.2022.01.027_bib30","doi-asserted-by":"crossref","first-page":"1863","DOI":"10.2146\/ajhp110464","article-title":"Declining susceptibilities of gram-negative bacteria to the fluoroquinolones: effects on pharmacokinetics, pharmacodynamics, and clinical outcomes","volume":"69","author":"Labreche","year":"2012","journal-title":"Am J Health Syst Pharm"},{"issue":"7","key":"10.1016\/j.mayocp.2022.01.027_bib31","doi-asserted-by":"crossref","first-page":"1369","DOI":"10.1007\/s10096-015-2361-6","article-title":"Cyst infection in autosomal dominant polycystic kidney disease: causative microorganisms and susceptibility to lipid-soluble antibiotics","volume":"34","author":"Suwabe","year":"2015","journal-title":"Eur J Clin Microbiol Infect Dis"},{"issue":"5","key":"10.1016\/j.mayocp.2022.01.027_bib32","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/j.medmal.2018.03.005","article-title":"Practice guidelines for the management of adult community-acquired urinary tract infections","volume":"48","author":"Caron","year":"2018","journal-title":"Med Mal Infect"},{"issue":"1","key":"10.1016\/j.mayocp.2022.01.027_bib33","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1007\/s00259-020-04903-x","article-title":"The use of a visual 4-point scoring scale improves the yield of 18F-FDG PET-CT imaging\u00a0in the diagnosis of renal and hepatic cyst infection in patients with autosomal dominant polycystic kidney disease","volume":"48","author":"Neuville","year":"2021","journal-title":"Eur J Nucl Med Mol Imaging"},{"issue":"1","key":"10.1016\/j.mayocp.2022.01.027_bib34","doi-asserted-by":"crossref","first-page":"16","DOI":"10.5414\/CNP58016","article-title":"Clinical aspects of renal transplantation in polycystic kidney disease","volume":"58","author":"Stiasny","year":"2002","journal-title":"Clin Nephrol"}],"container-title":["Mayo Clinic Proceedings"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0025619622000611?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0025619622000611?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,21]],"date-time":"2025-09-21T01:38:17Z","timestamp":1758418697000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0025619622000611"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,7]]},"references-count":34,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2022,7]]}},"alternative-id":["S0025619622000611"],"URL":"https:\/\/doi.org\/10.1016\/j.mayocp.2022.01.027","relation":{},"ISSN":["0025-6196"],"issn-type":[{"value":"0025-6196","type":"print"}],"subject":[],"published":{"date-parts":[[2022,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Efficacy of Prolonged Antibiotic Therapy for Renal Cyst Infections in Polycystic Kidney Disease","name":"articletitle","label":"Article Title"},{"value":"Mayo Clinic Proceedings","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.mayocp.2022.01.027","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Mayo Foundation for Medical Education and Research","name":"copyright","label":"Copyright"}]}}