{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,20]],"date-time":"2026-06-20T14:57:59Z","timestamp":1781967479130,"version":"3.54.5"},"reference-count":161,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,11,1]],"date-time":"2018-11-01T00:00:00Z","timestamp":1541030400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"MRC","award":["607310"],"award-info":[{"award-number":["607310"]}]},{"name":"European Union's Seventh Framework Programme"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Mathematical Biosciences"],"published-print":{"date-parts":[[2018,11]]},"DOI":"10.1016\/j.mbs.2018.07.008","type":"journal-article","created":{"date-parts":[[2018,8,1]],"date-time":"2018-08-01T02:26:35Z","timestamp":1533090395000},"page":"29-41","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":22,"special_numbering":"C","title":["Models in neuroendocrinology"],"prefix":"10.1016","volume":"305","author":[{"given":"Gareth","family":"Leng","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3046-6640","authenticated-orcid":false,"given":"Duncan J.","family":"MacGregor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"6","key":"10.1016\/j.mbs.2018.07.008_bib0001","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1111\/j.1365-2826.2008.01722.x","article-title":"Mathematical modelling in neuroendocrinology","volume":"20","author":"Leng","year":"2008","journal-title":"J. Neuroendocrinol."},{"issue":"2","key":"10.1016\/j.mbs.2018.07.008_bib0002","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1002\/cphy.c140034","article-title":"Mathematical modeling in neuroendocrinology","volume":"5","author":"Bertram","year":"2015","journal-title":"Compr. Physiol."},{"issue":"2","key":"10.1016\/j.mbs.2018.07.008_bib0003","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1137\/120892842","article-title":"Multiple geometric viewpoints of mixed mode dynamics associated with pseudo-plateau bursting","volume":"12","author":"Vo","year":"2013","journal-title":"SIAM J. Appl. Dyn. Syst."},{"issue":"4","key":"10.1016\/j.mbs.2018.07.008_bib0004","doi-asserted-by":"crossref","first-page":"1458","DOI":"10.1137\/110860136","article-title":"Mi","volume":"11","author":"Krupa","year":"2012","journal-title":"SIAM J. Appl. Dyn. Syst."},{"key":"10.1016\/j.mbs.2018.07.008_bib0005","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.mbs.2016.07.003","article-title":"Multi-timescale systems and fast-slow analysis","volume":"287","author":"Bertram","year":"2017","journal-title":"Math. Biosci."},{"issue":"2","key":"10.1016\/j.mbs.2018.07.008_bib0006","doi-asserted-by":"crossref","first-page":"T173","DOI":"10.1530\/JOE-15-0087","article-title":"60 years of neuroendocrinology: the posterior pituitary, from geoffrey harris to our present understanding","volume":"226","author":"Leng","year":"2015","journal-title":"J. Endocrinol."},{"issue":"1","key":"10.1016\/j.mbs.2018.07.008_bib0007","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/S0091-3022(02)00104-8","article-title":"The magnocellular oxytocin system, the fount of maternity: adaptations in pregnancy","volume":"24","author":"Russell","year":"2003","journal-title":"Front. Neuroendocrinol."},{"issue":"2","key":"10.1016\/j.mbs.2018.07.008_bib0008","first-page":"127","article-title":"Oxytocin: the great facilitator of life","volume":"88","author":"Lee","year":"2009","journal-title":"Prog. Neurobiol."},{"issue":"3","key":"10.1016\/j.mbs.2018.07.008_bib0009","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1016\/j.neuron.2016.03.033","article-title":"Oxytocin enhances social recognition by modulating cortical control of early olfactory processing","volume":"90","author":"Oettl","year":"2016","journal-title":"Neuron"},{"issue":"3","key":"10.1016\/j.mbs.2018.07.008_bib0010","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/j.biopsych.2015.06.004","article-title":"Oxytocin in general anxiety and social fear: a translational approach","volume":"79","author":"Neumann","year":"2016","journal-title":"Biol. Psychiatry"},{"issue":"3","key":"10.1016\/j.mbs.2018.07.008_bib0011","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1016\/j.neuron.2011.11.030","article-title":"Evoked axonal oxytocin release in the central amygdala attenuates fear response","volume":"73","author":"Knobloch","year":"2012","journal-title":"Neuron"},{"issue":"5","key":"10.1016\/j.mbs.2018.07.008_bib0012","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/j.tem.2017.02.007","article-title":"Oxytocin - The Sweet Hormone?","volume":"28","author":"Leng","year":"2017","journal-title":"Trends Endocrinol. Metab."},{"issue":"3","key":"10.1016\/j.mbs.2018.07.008_bib0013","doi-asserted-by":"crossref","first-page":"1317","DOI":"10.1210\/endo-128-3-1317","article-title":"Oxytocin produces natriuresis in rats at physiological plasma concentrations","volume":"128","author":"Verbalis","year":"1991","journal-title":"Endocrinology"},{"key":"10.1016\/j.mbs.2018.07.008_bib0014","doi-asserted-by":"crossref","unstructured":"Antunes-Rodrigues, J., et\u00a0al., The neuroendocrine control of atrial natriuretic peptide release. Mol Psychiatry, 1997. 2(5): p. 359\u201367.","DOI":"10.1038\/sj.mp.4000308"},{"key":"10.1016\/j.mbs.2018.07.008_bib0015","doi-asserted-by":"crossref","first-page":"31","DOI":"10.3389\/fnbeh.2014.00031","article-title":"Evolution of oxytocin pathways in the brain of vertebrates","volume":"8","author":"Knobloch","year":"2014","journal-title":"Front. Behav. Neurosci."},{"issue":"7287","key":"10.1016\/j.mbs.2018.07.008_bib0016","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1038\/nature08826","article-title":"An intrinsic vasopressin system in the olfactory bulb is involved in social recognition","volume":"464","author":"Tobin","year":"2010","journal-title":"Nature"},{"issue":"11","key":"10.1016\/j.mbs.2018.07.008_bib0017","doi-asserted-by":"crossref","first-page":"3497","DOI":"10.1113\/JP274025","article-title":"Vasopressin casts light on the suprachiasmatic nucleus","volume":"595","author":"Tsuji","year":"2017","journal-title":"J. Physiol."},{"key":"10.1016\/j.mbs.2018.07.008_bib0018","article-title":"Diversity of oxytocin neurons: beyond magno- and parvocellular cell types?","author":"Althammer","year":"2017","journal-title":"J. Neuroendocrinol."},{"issue":"23","key":"10.1016\/j.mbs.2018.07.008_bib0019","doi-asserted-by":"crossref","first-page":"5625","DOI":"10.1113\/jphysiol.2008.159103","article-title":"Neurotransmitters and peptides: whispered secrets and public announcements","volume":"586","author":"Leng","year":"2008","journal-title":"J. Physiol"},{"issue":"11","key":"10.1016\/j.mbs.2018.07.008_bib0020","doi-asserted-by":"crossref","first-page":"982","DOI":"10.1016\/j.tips.2017.08.005","article-title":"The action radius of oxytocin release in the mammalian cns: from single vesicles to behavior","volume":"38","author":"Chini","year":"2017","journal-title":"Trends Pharmacol. Sci."},{"issue":"4","key":"10.1016\/j.mbs.2018.07.008_bib0021","doi-asserted-by":"crossref","first-page":"1701","DOI":"10.1002\/cphy.c150053","article-title":"Magnocellular neurons and posterior pituitary function","volume":"6","author":"Brown","year":"2016","journal-title":"Compr. Physiol."},{"issue":"8","key":"10.1016\/j.mbs.2018.07.008_bib0022","doi-asserted-by":"crossref","first-page":"678","DOI":"10.1111\/jne.12051","article-title":"Physiological regulation of magnocellular neurosecretory cell activity: integration of intrinsic, local and afferent mechanisms","volume":"25","author":"Brown","year":"2013","journal-title":"J. Neuroendocrinol."},{"issue":"6","key":"10.1016\/j.mbs.2018.07.008_bib0023","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1111\/j.1365-2826.2006.01428.x","article-title":"Jacques Benoit Lecture. Information processing in the hypothalamus: peptides and analogue computation","volume":"18","author":"Leng","year":"2006","journal-title":"J. Neuroendocrinol."},{"issue":"17","key":"10.1016\/j.mbs.2018.07.008_bib0024","doi-asserted-by":"crossref","first-page":"6967","DOI":"10.1523\/JNEUROSCI.21-17-06967.2001","article-title":"Responses of magnocellular neurons to osmotic stimulation involves coactivation of excitatory and inhibitory input: an experimental and theoretical analysis","volume":"21","author":"Leng","year":"2001","journal-title":"J. Neurosci."},{"key":"10.1016\/j.mbs.2018.07.008_bib0025","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1242\/jeb.139.1.51","article-title":"Optimizing release from peptide hormone secretory nerve terminals","volume":"139","author":"Bicknell","year":"1988","journal-title":"J. Exp. Biol."},{"issue":"2","key":"10.1016\/j.mbs.2018.07.008_bib0026","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1007\/BF00236303","article-title":"Facilitation of milk ejection-related activation of oxytocin-secreting neurones by osmotic stimulation in the rat","volume":"65","author":"Negoro","year":"1987","journal-title":"Exp. Brain Res."},{"issue":"3","key":"10.1016\/j.mbs.2018.07.008_bib0027","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1023\/A:1027424128972","article-title":"AHP's, HAP's and DAP's: how potassium currents regulate the excitability of rat supraoptic neurones","volume":"15","author":"Roper","year":"2003","journal-title":"J. Comput. Neurosci."},{"issue":"7","key":"10.1016\/j.mbs.2018.07.008_bib0028","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1038\/nrn2400","article-title":"Central mechanisms of osmosensation and systemic osmoregulation","volume":"9","author":"Bourque","year":"2008","journal-title":"Nat. Rev. Neurosci."},{"issue":"4","key":"10.1016\/j.mbs.2018.07.008_bib0029","doi-asserted-by":"crossref","DOI":"10.1111\/jne.12358","article-title":"Oxytocin neurones: intrinsic mechanisms governing the regularity of spiking activity","volume":"28","author":"Maicas Royo","year":"2016","journal-title":"J. Neuroendocrinol."},{"issue":"7","key":"10.1016\/j.mbs.2018.07.008_bib0030","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0180368","article-title":"Spike patterning in oxytocin neurons: capturing physiological behaviour with Hodgkin-Huxley and integrate-and-fire models","volume":"12","author":"Leng","year":"2017","journal-title":"PLoS One"},{"key":"10.1016\/j.mbs.2018.07.008_bib0031","doi-asserted-by":"crossref","DOI":"10.1210\/en.2017-03068","article-title":"A predictive, quantitative model of spiking activity and stimulus-secretion coupling in oxytocin neurons","author":"Maicas-Royo","year":"2018","journal-title":"Endocrinology"},{"key":"10.1016\/j.mbs.2018.07.008_bib0032","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/S0079-6123(08)00410-X","article-title":"Neuron-glia interactions in the rat supraoptic nucleus","volume":"170","author":"Oliet","year":"2008","journal-title":"Prog. Brain Res."},{"issue":"6893","key":"10.1016\/j.mbs.2018.07.008_bib0033","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1038\/nature00822","article-title":"Intracellular calcium stores regulate activity-dependent neuropeptide release from dendrites","volume":"418","author":"Ludwig","year":"2002","journal-title":"Nature"},{"key":"10.1016\/j.mbs.2018.07.008_bib0034","doi-asserted-by":"crossref","first-page":"261","DOI":"10.3389\/fphys.2012.00261","article-title":"The involvement of actin, calcium channels and exocytosis proteins in somato-dendritic oxytocin and vasopressin release","volume":"3","author":"Tobin","year":"2012","journal-title":"Front Physiol."},{"issue":"10","key":"10.1016\/j.mbs.2018.07.008_bib0035","doi-asserted-by":"crossref","first-page":"e25366","DOI":"10.1371\/journal.pone.0025366","article-title":"The involvement of voltage-operated calcium channels in somato-dendritic oxytocin release","volume":"6","author":"Tobin","year":"2011","journal-title":"PLoS One"},{"issue":"2","key":"10.1016\/j.mbs.2018.07.008_bib0036","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1038\/nrn1845","article-title":"Dendritic peptide release and peptide-dependent behaviours","volume":"7","author":"Ludwig","year":"2006","journal-title":"Nat. Rev. Neurosci."},{"issue":"7","key":"10.1016\/j.mbs.2018.07.008_bib0037","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pcbi.1000123","article-title":"Emergent synchronous bursting of oxytocin neuronal network","volume":"4","author":"Rossoni","year":"2008","journal-title":"PLoS Comput. Biol."},{"issue":"6","key":"10.1016\/j.mbs.2018.07.008_bib0038","doi-asserted-by":"crossref","first-page":"e38402","DOI":"10.1371\/journal.pone.0038402","article-title":"Bifurcations of emergent bursting in a neuronal network","volume":"7","author":"Wu","year":"2012","journal-title":"PLoS One"},{"issue":"3","key":"10.1016\/j.mbs.2018.07.008_bib0039","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/j.jbiotec.2010.01.003","article-title":"Coherent peptide-mediated activity in a neuronal network controlled by subcellular signaling pathway: experiments and modeling","volume":"149","author":"Zhang","year":"2010","journal-title":"J. Biotechnol."},{"key":"10.1016\/j.mbs.2018.07.008_bib0040","series-title":"The Heart of the Brain: The Hypothalamus and its Hormones","first-page":"280","author":"Leng","year":"2018"},{"key":"10.1016\/j.mbs.2018.07.008_bib0041","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1146\/annurev.physiol.59.1.601","article-title":"Osmoreceptors in the central nervous system","volume":"59","author":"Bourque","year":"1997","journal-title":"Annu. Rev. Physiol."},{"issue":"6","key":"10.1016\/j.mbs.2018.07.008_bib0042","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1111\/jne.12270","article-title":"Mechanical basis of osmosensory transduction in magnocellular neurosecretory neurones of the rat supraoptic nucleus","volume":"27","author":"Prager-Khoutorsky","year":"2015","journal-title":"J. Neuroendocrinol."},{"issue":"1","key":"10.1016\/j.mbs.2018.07.008_bib0043","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1159\/000123280","article-title":"The supraoptic nucleus as an osmoreceptor","volume":"34","author":"Leng","year":"1982","journal-title":"Neuroendocrinology"},{"issue":"20","key":"10.1016\/j.mbs.2018.07.008_bib0044","doi-asserted-by":"crossref","first-page":"4818","DOI":"10.1523\/JNEUROSCI.4203-03.2004","article-title":"Burst initiation and termination in phasic vasopressin cells of the rat supraoptic nucleus: a combined mathematical, electrical, and calcium fluorescence study","volume":"24","author":"Roper","year":"2004","journal-title":"J. Neurosci."},{"issue":"2","key":"10.1016\/j.mbs.2018.07.008_bib0045","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1111\/j.1365-2826.2006.01509.x","article-title":"Bistability with hysteresis in the activity of vasopressin cells","volume":"19","author":"Sabatier","year":"2007","journal-title":"J. Neuroendocrinol."},{"issue":"3","key":"10.1016\/j.mbs.2018.07.008_bib0046","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1159\/000149827","article-title":"Population dynamics in vasopressin cells","volume":"88","author":"Leng","year":"2008","journal-title":"Neuroendocrinology"},{"issue":"2","key":"10.1016\/j.mbs.2018.07.008_bib0047","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.biosystems.2013.03.010","article-title":"Information coding in vasopressin neurons\u2013the role of asynchronous bistable burst firing","volume":"112","author":"MacGregor","year":"2013","journal-title":"Biosystems"},{"issue":"10","key":"10.1016\/j.mbs.2018.07.008_bib0048","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pcbi.1002740","article-title":"Phasic firing in vasopressin cells: understanding its functional significance through computational models","volume":"8","author":"MacGregor","year":"2012","journal-title":"PLoS Comput. Biol."},{"issue":"8","key":"10.1016\/j.mbs.2018.07.008_bib0049","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pcbi.1003187","article-title":"Spike triggered hormone secretion in vasopressin cells; a model investigation of mechanism and heterogeneous population function","volume":"9","author":"MacGregor","year":"2013","journal-title":"PLoS Comput. Biol."},{"issue":"5","key":"10.1016\/j.mbs.2018.07.008_bib0050","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1038\/nrendo.2016.193","article-title":"An updated view of hypothalamic-vascular-pituitary unit function and plasticity","volume":"13","author":"Le Tissier","year":"2017","journal-title":"Nat. Rev. Endocrinol."},{"issue":"2","key":"10.1016\/j.mbs.2018.07.008_bib0051","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.ando.2012.03.033","article-title":"Pituitary endocrine cell networks - 10 years and beyond","volume":"73","author":"Hodson","year":"2012","journal-title":"Ann. Endocrinol. (Paris)"},{"issue":"3-4","key":"10.1016\/j.mbs.2018.07.008_bib0052","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1016\/j.ceca.2011.11.007","article-title":"Coordination of calcium signals by pituitary endocrine cells in situ","volume":"51","author":"Hodson","year":"2012","journal-title":"Cell Calcium"},{"issue":"6","key":"10.1016\/j.mbs.2018.07.008_bib0053","doi-asserted-by":"crossref","first-page":"1849","DOI":"10.1210\/en.2017-00107","article-title":"Heterogeneity of calcium responses to secretagogues in corticotrophs from male rats","volume":"158","author":"Romano","year":"2017","journal-title":"Endocrinology"},{"issue":"3","key":"10.1016\/j.mbs.2018.07.008_bib0054","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1677\/joe.0.1800351","article-title":"Photoperiodic regulation of prolactin secretion: changes in intra-pituitary signalling and lactotroph heterogeneity","volume":"180","author":"Johnston","year":"2004","journal-title":"J. Endocrinol."},{"issue":"12","key":"10.1016\/j.mbs.2018.07.008_bib0055","doi-asserted-by":"crossref","first-page":"1279","DOI":"10.1111\/j.1365-2826.2010.02061.x","article-title":"Investigating heterogeneity of intracellular calcium dynamics in anterior pituitary lactotrophs using a combined modelling\/experimental approach","volume":"22","author":"Tomaiuolo","year":"2010","journal-title":"J. Neuroendocrinol."},{"issue":"4","key":"10.1016\/j.mbs.2018.07.008_bib0056","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1159\/000350790","article-title":"Cells co-expressing luteinising hormone and thyroid-stimulating hormone are present in the ovine pituitary pars distalis but not the pars tuberalis: implications for the control of endogenous circannual rhythms of prolactin","volume":"97","author":"Hodson","year":"2013","journal-title":"Neuroendocrinology"},{"key":"10.1016\/j.mbs.2018.07.008_bib0057","article-title":"Control of anterior pituitary cell excitability by calcium-activated potassium channels","author":"Shipston","year":"2017","journal-title":"Mol. Cell. Endocrinol."},{"issue":"C","key":"10.1016\/j.mbs.2018.07.008_bib0058","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.mce.2017.06.022","article-title":"Common and diverse elements of ion channels and receptors underlying electrical activity in endocrine pituitary cells","volume":"463","author":"Fletcher","year":"2018","journal-title":"Mol. Cell. Endocrinol."},{"issue":"7","key":"10.1016\/j.mbs.2018.07.008_bib0059","doi-asserted-by":"crossref","first-page":"E515","DOI":"10.1152\/ajpendo.00500.2015","article-title":"Is bursting more effective than spiking in evoking pituitary hormone secretion? A spatiotemporal simulation study of calcium and granule dynamics","volume":"310","author":"Tagliavini","year":"2016","journal-title":"Am. J. Physiol. Endocrinol. Metab."},{"key":"10.1016\/j.mbs.2018.07.008_bib0060","doi-asserted-by":"crossref","DOI":"10.1016\/j.cels.2017.10.013","article-title":"Asymmetry between activation and deactivation during a transcriptional pulse","author":"Dunham","year":"2017","journal-title":"Cell Syst."},{"issue":"4","key":"10.1016\/j.mbs.2018.07.008_bib0061","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pbio.1000607","article-title":"Dynamic analysis of stochastic transcription cycles","volume":"9","author":"Harper","year":"2011","journal-title":"PLoS Biol."},{"issue":"4","key":"10.1016\/j.mbs.2018.07.008_bib0062","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1093\/biostatistics\/kxv010","article-title":"A stochastic transcriptional switch model for single cell imaging data","volume":"16","author":"Hey","year":"2015","journal-title":"Biostatistics"},{"issue":"3","key":"10.1016\/j.mbs.2018.07.008_bib0063","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1016\/S0006-3495(95)79952-0","article-title":"Spontaneous electrical and calcium oscillations in unstimulated pituitary gonadotrophs","volume":"69","author":"Li","year":"1995","journal-title":"Biophys. J."},{"issue":"6","key":"10.1016\/j.mbs.2018.07.008_bib0064","doi-asserted-by":"crossref","first-page":"3775","DOI":"10.1529\/biophysj.104.050955","article-title":"Filtering of calcium transients by the endoplasmic reticulum in pancreatic beta-cells","volume":"87","author":"Bertram","year":"2004","journal-title":"Biophys. J."},{"issue":"3","key":"10.1016\/j.mbs.2018.07.008_bib0065","doi-asserted-by":"crossref","first-page":"1080","DOI":"10.1016\/S0006-3495(97)78758-7","article-title":"Sensing and refilling calcium stores in an excitable cell","volume":"72","author":"Li","year":"1997","journal-title":"Biophys. J."},{"issue":"16","key":"10.1016\/j.mbs.2018.07.008_bib0066","doi-asserted-by":"crossref","first-page":"5902","DOI":"10.1523\/JNEUROSCI.21-16-05902.2001","article-title":"Paradoxical role of large-conductance calcium-activated K+ (BK) channels in controlling action potential-driven Ca2+ entry in anterior pituitary cells","volume":"21","author":"Van Goor","year":"2001","journal-title":"J. Neurosci."},{"issue":"8","key":"10.1016\/j.mbs.2018.07.008_bib0067","doi-asserted-by":"crossref","first-page":"2211","DOI":"10.1007\/s11538-008-9341-2","article-title":"A mathematical model for the actions of activin, inhibin, and follistatin on pituitary gonadotrophs","volume":"70","author":"Bertram","year":"2008","journal-title":"Bull. Math. Biol."},{"issue":"1-2","key":"10.1016\/j.mbs.2018.07.008_bib0068","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.mce.2013.09.012","article-title":"GnRH pulse frequency-dependent differential regulation of LH and FSH gene expression","volume":"385","author":"Thompson","year":"2014","journal-title":"Mol. Cell Endocrinol."},{"issue":"23","key":"10.1016\/j.mbs.2018.07.008_bib0069","doi-asserted-by":"crossref","first-page":"9815","DOI":"10.1074\/jbc.M117.783886","article-title":"Modeling and high-throughput experimental data uncover the mechanisms underlying Fshb gene sensitivity to gonadotropin-releasing hormone pulse frequency","volume":"292","author":"Stern","year":"2017","journal-title":"J. Biol. Chem."},{"issue":"1","key":"10.1016\/j.mbs.2018.07.008_bib0070","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.mbs.2013.09.006","article-title":"A mathematical model of pulse-coded hormone signal responses in pituitary gonadotroph cells","volume":"246","author":"Magill","year":"2013","journal-title":"Math. Biosci."},{"issue":"3","key":"10.1016\/j.mbs.2018.07.008_bib0071","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1677\/joe.0.0690359","article-title":"Priming effect of luteinizing hormone releasing factor elicited by preoptic stimulation and by intravenous infusion and multiple injections of the synthetic decapeptide","volume":"69","author":"Fink","year":"1976","journal-title":"J. Endocrinol."},{"issue":"4","key":"10.1016\/j.mbs.2018.07.008_bib0072","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1007\/s11064-007-9500-0","article-title":"Priming in oxytocin cells and in gonadotrophs","volume":"33","author":"Leng","year":"2008","journal-title":"Neurochem. Res."},{"issue":"3","key":"10.1016\/j.mbs.2018.07.008_bib0073","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1111\/j.0953-8194.2004.01169.x","article-title":"Modelling the pituitary response to luteinizing hormone-releasing hormone","volume":"16","author":"Scullion","year":"2004","journal-title":"J. Neuroendocrinol."},{"key":"10.1016\/j.mbs.2018.07.008_bib0074","doi-asserted-by":"crossref","DOI":"10.1155\/2013\/410348","article-title":"A two-pathway mathematical model of the lh response to gnrh that predicts self-priming","volume":"2013","author":"Evans","year":"2013","journal-title":"Int. J. Endocrinol."},{"issue":"1","key":"10.1016\/j.mbs.2018.07.008_bib0075","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1073\/pnas.91.1.58","article-title":"Calcium oscillations in pituitary gonadotrophs: comparison of experiment and theory","volume":"91","author":"Li","year":"1994","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"issue":"2","key":"10.1016\/j.mbs.2018.07.008_bib0076","doi-asserted-by":"crossref","first-page":"E263","DOI":"10.1152\/ajpendo.2000.278.2.E263","article-title":"A mathematical model quantifying GnRH-induced LH secretion from gonadotropes","volume":"278","author":"Blum","year":"2000","journal-title":"Am. J. Physiol. Endocrinol. Metab."},{"key":"10.1016\/j.mbs.2018.07.008_bib0077","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1186\/1742-4682-1-9","article-title":"A mathematical model for LH release in response to continuous and pulsatile exposure of gonadotrophs to GnRH","volume":"1","author":"Washington","year":"2004","journal-title":"Theor. Biol. Med. Model"},{"issue":"11","key":"10.1016\/j.mbs.2018.07.008_bib0078","doi-asserted-by":"crossref","first-page":"7873","DOI":"10.1074\/jbc.M113.532473","article-title":"Pulsatile hormonal signaling to extracellular signal-regulated kinase: exploring system sensitivity to gonadotropin-releasing hormone pulse frequency and width","volume":"289","author":"Perrett","year":"2014","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.mbs.2018.07.008_bib0079","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.mbs.2014.08.011","article-title":"Modeling endocrine regulation of the menstrual cycle using delay differential equations","volume":"257","author":"Harris","year":"2014","journal-title":"Math. Biosci."},{"issue":"1","key":"10.1016\/j.mbs.2018.07.008_bib0080","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1007\/s11538-013-9913-7","article-title":"Modeling endocrine control of the pituitary-ovarian axis: androgenic influence and chaotic dynamics","volume":"76","author":"Hendrix","year":"2014","journal-title":"Bull. Math. Biol."},{"key":"10.1016\/j.mbs.2018.07.008_bib0081","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.jtbi.2012.11.020","article-title":"A mathematical model of the human menstrual cycle for the administration of GnRH analogues","volume":"321","author":"Roblitz","year":"2013","journal-title":"J. Theor. Biol."},{"issue":"1","key":"10.1016\/j.mbs.2018.07.008_bib0082","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1186\/2190-8567-3-4","article-title":"A network model of the periodic synchronization process in the dynamics of calcium concentration in GnRH neurons","volume":"3","author":"Krupa","year":"2013","journal-title":"J. Math. Neurosci."},{"issue":"26","key":"10.1016\/j.mbs.2018.07.008_bib0083","doi-asserted-by":"crossref","first-page":"10835","DOI":"10.1073\/pnas.0903463106","article-title":"Dendro-dendritic bundling and shared synapses between gonadotropin-releasing hormone neurons","volume":"106","author":"Campbell","year":"2009","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"issue":"12","key":"10.1016\/j.mbs.2018.07.008_bib0084","doi-asserted-by":"crossref","first-page":"1251","DOI":"10.1111\/j.1365-2826.2010.02055.x","article-title":"A dynamical model for the control of the gonadotrophin-releasing hormone neurosecretory system","volume":"22","author":"Vidal","year":"2010","journal-title":"J. Neuroendocrinol."},{"issue":"4","key":"10.1016\/j.mbs.2018.07.008_bib0085","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1111\/j.1365-2826.2009.01835.x","article-title":"Oestrogen, kisspeptin, GPR54 and the pre-ovulatory luteinising hormone surge","volume":"21","author":"Clarkson","year":"2009","journal-title":"J. Neuroendocrinol."},{"issue":"47","key":"10.1016\/j.mbs.2018.07.008_bib0086","doi-asserted-by":"crossref","first-page":"E10216","DOI":"10.1073\/pnas.1713897114","article-title":"Definition of the hypothalamic GnRH pulse generator in mice","volume":"114","author":"Clarkson","year":"2017","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"issue":"7","key":"10.1016\/j.mbs.2018.07.008_bib0087","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1111\/j.1365-2826.2010.02033.x","article-title":"Gonadotrophin-releasing hormone nerve terminals, tanycytes and neurohaemal junction remodelling in the adult median eminence: functional consequences for reproduction and dynamic role of vascular endothelial cells","volume":"22","author":"Prevot","year":"2010","journal-title":"J. Neuroendocrinol."},{"issue":"1-2","key":"10.1016\/j.mbs.2018.07.008_bib0088","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1159\/000368364","article-title":"Multitasking in gonadotropin-releasing hormone neuron dendrites","volume":"102","author":"Iremonger","year":"2015","journal-title":"Neuroendocrinology"},{"issue":"6","key":"10.1016\/j.mbs.2018.07.008_bib0089","doi-asserted-by":"crossref","first-page":"904","DOI":"10.1007\/s11538-014-0052-6","article-title":"A computational model of the dendron of the gnrh neuron","volume":"77","author":"Chen","year":"2015","journal-title":"Bull. Math. Biol."},{"issue":"3","key":"10.1016\/j.mbs.2018.07.008_bib0090","doi-asserted-by":"crossref","first-page":"1310","DOI":"10.1016\/S0006-3495(00)76384-3","article-title":"Amplitude-dependent spike-broadening and enhanced Ca(2+) signaling in GnRH-secreting neurons","volume":"79","author":"Van Goor","year":"2000","journal-title":"Biophys. J."},{"issue":"24","key":"10.1016\/j.mbs.2018.07.008_bib0091","doi-asserted-by":"crossref","first-page":"9290","DOI":"10.1523\/JNEUROSCI.20-24-09290.2000","article-title":"Modeling of membrane excitability in gonadotropin-releasing hormone-secreting hypothalamic neurons regulated by Ca2+-mobilizing and adenylyl cyclase-coupled receptors","volume":"20","author":"LeBeau","year":"2000","journal-title":"J. Neurosci."},{"issue":"1","key":"10.1016\/j.mbs.2018.07.008_bib0092","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.jtbi.2011.01.035","article-title":"A mathematical model of adult GnRH neurons in mouse brain and its bifurcation analysis","volume":"276","author":"Duan","year":"2011","journal-title":"J. Theor. Biol."},{"issue":"18","key":"10.1016\/j.mbs.2018.07.008_bib0093","doi-asserted-by":"crossref","first-page":"6214","DOI":"10.1523\/JNEUROSCI.6156-09.2010","article-title":"Two slow calcium-activated afterhyperpolarization currents control burst firing dynamics in gonadotropin-releasing hormone neurons","volume":"30","author":"Lee","year":"2010","journal-title":"J. Neurosci."},{"issue":"10","key":"10.1016\/j.mbs.2018.07.008_bib0094","doi-asserted-by":"crossref","first-page":"1941","DOI":"10.1007\/s11538-013-9877-7","article-title":"Regulation of electrical bursting in a spatiotemporal model of a GnRH neuron","volume":"75","author":"Chen","year":"2013","journal-title":"Bull. Math. Biol."},{"issue":"12","key":"10.1016\/j.mbs.2018.07.008_bib0095","doi-asserted-by":"crossref","first-page":"1267","DOI":"10.1111\/j.1365-2826.2010.02084.x","article-title":"Pituitary network connectivity as a mechanism for the luteinising hormone surge","volume":"22","author":"Lyles","year":"2010","journal-title":"J. Neuroendocrinol."},{"issue":"1","key":"10.1016\/j.mbs.2018.07.008_bib0096","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/S0006-3495(92)81824-6","article-title":"Pulsatile signaling in intercellular communication. Periodic stimuli are more efficient than random or chaotic signals in a model based on receptor desensitization.","volume":"61","author":"Li","year":"1992","journal-title":"Biophys. J."},{"issue":"1","key":"10.1016\/j.mbs.2018.07.008_bib0097","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/S0006-3495(89)82785-7","article-title":"Frequency specificity in intercellular communication. Influence of patterns of periodic signaling on target cell responsiveness.","volume":"55","author":"Li","year":"1989","journal-title":"Biophys. J."},{"issue":"1-2","key":"10.1016\/j.mbs.2018.07.008_bib0098","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/j.anireprosci.2005.05.032","article-title":"GnRHs and GnRH receptors","volume":"88","author":"Millar","year":"2005","journal-title":"Anim. Reprod. Sci."},{"issue":"66","key":"10.1016\/j.mbs.2018.07.008_bib0099","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1098\/rsif.2011.0215","article-title":"Decoding GnRH neurohormone pulse frequency by convergent signalling modules","volume":"9","author":"Tsaneva-Atanasova","year":"2012","journal-title":"J. R. Soc. Interface"},{"issue":"4","key":"10.1016\/j.mbs.2018.07.008_bib0100","doi-asserted-by":"crossref","first-page":"e95613","DOI":"10.1371\/journal.pone.0095613","article-title":"Interpreting frequency responses to dose-conserved pulsatile input signals in simple cell signaling motifs","volume":"9","author":"Fletcher","year":"2014","journal-title":"PLoS One"},{"issue":"1","key":"10.1016\/j.mbs.2018.07.008_bib0101","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1152\/jn.00872.2006","article-title":"Mechanism of spontaneous and receptor-controlled electrical activity in pituitary somatotrophs: experiments and theory","volume":"98","author":"Tsaneva-Atanasova","year":"2007","journal-title":"J. Neurophysiol."},{"issue":"6008","key":"10.1016\/j.mbs.2018.07.008_bib0102","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1038\/314281a0","article-title":"Growth induced by pulsatile infusion of an amidated fragment of human growth hormone releasing factor in normal and GHRF-deficient rats","volume":"314","author":"Clark","year":"1985","journal-title":"Nature"},{"issue":"11","key":"10.1016\/j.mbs.2018.07.008_bib0103","doi-asserted-by":"crossref","first-page":"936","DOI":"10.1111\/j.1365-2826.2004.01252.x","article-title":"Estimation of parameters for a mathematical model of growth hormone secretion","volume":"16","author":"Brown","year":"2004","journal-title":"J. Neuroendocrinol."},{"issue":"12","key":"10.1016\/j.mbs.2018.07.008_bib0104","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1111\/j.1365-2826.2005.01370.x","article-title":"Modelling the hypothalamic control of growth hormone secretion","volume":"17","author":"MacGregor","year":"2005","journal-title":"J. Neuroendocrinol."},{"key":"10.1016\/j.mbs.2018.07.008_bib0105","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/S0076-6879(08)03814-7","article-title":"Biomathematical modeling of pulsatile hormone secretion: a historical perspective","volume":"454","author":"Evans","year":"2009","journal-title":"Methods Enzymol."},{"issue":"3","key":"10.1016\/j.mbs.2018.07.008_bib0106","doi-asserted-by":"crossref","first-page":"R753","DOI":"10.1152\/ajpregu.00407.2001","article-title":"Unequal autonegative feedback by GH models the sexual dimorphism in GH secretory dynamics","volume":"282","author":"Farhy","year":"2002","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"issue":"1","key":"10.1016\/j.mbs.2018.07.008_bib0107","doi-asserted-by":"crossref","first-page":"R38","DOI":"10.1152\/ajpregu.2001.281.1.R38","article-title":"A construct of interactive feedback control of the GH axis in the male","volume":"281","author":"Farhy","year":"2001","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"issue":"6","key":"10.1016\/j.mbs.2018.07.008_bib0108","doi-asserted-by":"crossref","first-page":"R1030","DOI":"10.1152\/ajpregu.00473.2003","article-title":"Putative GH pulse renewal: periventricular somatostatinergic control of an arcuate-nuclear somatostatin and GH-releasing hormone oscillator","volume":"286","author":"Farhy","year":"2004","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"issue":"4","key":"10.1016\/j.mbs.2018.07.008_bib0109","first-page":"943","article-title":"Neuroendocrine responses to a novel growth hormone secretagogue, L-692,429, in healthy older subjects","volume":"79","author":"Aloi","year":"1994","journal-title":"J. Clin. Endocrinol. Metab."},{"issue":"7","key":"10.1016\/j.mbs.2018.07.008_bib0110","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1111\/jne.12278","article-title":"Nutrient sensing overrides somatostatin and growth hormone-releasing hormone to control pulsatile growth hormone release","volume":"27","author":"Steyn","year":"2015","journal-title":"J. Neuroendocrinol."},{"issue":"2","key":"10.1016\/j.mbs.2018.07.008_bib0111","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/0306-4522(93)90197-N","article-title":"Systemic administration of growth hormone-releasing peptide activates hypothalamic arcuate neurons","volume":"53","author":"Dickson","year":"1993","journal-title":"Neuroscience"},{"issue":"5","key":"10.1016\/j.mbs.2018.07.008_bib0112","doi-asserted-by":"crossref","first-page":"1537","DOI":"10.1210\/endo-114-5-1537","article-title":"On the in vitro and in vivo activity of a new synthetic hexapeptide that acts on the pituitary to specifically release growth hormone","volume":"114","author":"Bowers","year":"1984","journal-title":"Endocrinology"},{"issue":"5","key":"10.1016\/j.mbs.2018.07.008_bib0113","doi-asserted-by":"crossref","first-page":"E1085","DOI":"10.1152\/ajpendo.91001.2008","article-title":"Determinants of GH-releasing hormone and GH-releasing peptide synergy in men","volume":"296","author":"Veldhuis","year":"2009","journal-title":"Am. J. Physiol. Endocrinol. Metab."},{"issue":"4","key":"10.1016\/j.mbs.2018.07.008_bib0114","doi-asserted-by":"crossref","first-page":"R1577","DOI":"10.1152\/ajpregu.00584.2006","article-title":"Model-projected mechanistic bases for sex differences in growth hormone regulation in humans","volume":"292","author":"Farhy","year":"2007","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"issue":"5277","key":"10.1016\/j.mbs.2018.07.008_bib0115","doi-asserted-by":"crossref","first-page":"974","DOI":"10.1126\/science.273.5277.974","article-title":"A receptor in pituitary and hypothalamus that functions in growth hormone release","volume":"273","author":"Howard","year":"1996","journal-title":"Science"},{"issue":"6762","key":"10.1016\/j.mbs.2018.07.008_bib0116","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1038\/45230","article-title":"Ghrelin is a growth-hormone-releasing acylated peptide from stomach","volume":"402","author":"Kojima","year":"1999","journal-title":"Nature"},{"issue":"3","key":"10.1016\/j.mbs.2018.07.008_bib0117","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.1016\/S0006-3495(97)78159-1","article-title":"Generation of action potentials in a mathematical model of corticotrophs","volume":"73","author":"LeBeau","year":"1997","journal-title":"Biophys. J."},{"issue":"3","key":"10.1016\/j.mbs.2018.07.008_bib0118","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1006\/jtbi.1998.0656","article-title":"Analysis of a reduced model of corticotroph action potentials","volume":"192","author":"LeBeau","year":"1998","journal-title":"J. Theor. Biol."},{"issue":"1","key":"10.1016\/j.mbs.2018.07.008_bib0119","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1210\/endo-129-1-409","article-title":"Spontaneous and corticotropin-releasing factor-induced cytosolic calcium transients in corticotrophs","volume":"129","author":"Guerineau","year":"1991","journal-title":"Endocrinology"},{"issue":"8","key":"10.1016\/j.mbs.2018.07.008_bib0120","doi-asserted-by":"crossref","first-page":"3108","DOI":"10.1210\/en.2016-1115","article-title":"Glucocorticoids inhibit CRH\/AVP-evoked bursting activity of male murine anterior pituitary corticotrophs","volume":"157","author":"Duncan","year":"2016","journal-title":"Endocrinology"},{"issue":"2","key":"10.1016\/j.mbs.2018.07.008_bib0121","doi-asserted-by":"crossref","first-page":"T55","DOI":"10.1530\/JOE-15-0132","article-title":"60 years of neuroendocrinology: glucocorticoid dynamics: insights from mathematical, experimental and clinical studies","volume":"226","author":"Spiga","year":"2015","journal-title":"J. Endocrinol."},{"issue":"1","key":"10.1016\/j.mbs.2018.07.008_bib0122","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1016\/j.mbs.2013.08.010","article-title":"Mathematical modeling of the hypothalamic-pituitary-adrenal gland (HPA) axis, including hippocampal mechanisms","volume":"246","author":"Andersen","year":"2013","journal-title":"Math. Biosci."},{"issue":"4","key":"10.1016\/j.mbs.2018.07.008_bib0123","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1007\/s00285-010-0384-2","article-title":"The minimal model of the hypothalamic-pituitary-adrenal axis","volume":"63","author":"Vinther","year":"2011","journal-title":"J. Math. Biol."},{"issue":"2","key":"10.1016\/j.mbs.2018.07.008_bib0124","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.mbs.2005.06.006","article-title":"Mathematical modeling of the hypothalamic-pituitary-adrenal system activity","volume":"197","author":"Jelic","year":"2005","journal-title":"Math. Biosci."},{"key":"10.1016\/j.mbs.2018.07.008_bib0125","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1186\/1742-4682-4-8","article-title":"Inclusion of the glucocorticoid receptor in a hypothalamic pituitary adrenal axis model reveals bistability","volume":"4","author":"Gupta","year":"2007","journal-title":"Theor. Biol. Med. Model"},{"issue":"12","key":"10.1016\/j.mbs.2018.07.008_bib0126","doi-asserted-by":"crossref","first-page":"1977","DOI":"10.1109\/TBME.2005.857671","article-title":"Modeling robust oscillatory behavior of the hypothalamic-pituitary-adrenal axis","volume":"52","author":"Kyrylov","year":"2005","journal-title":"IEEE Trans. Biomed Eng."},{"issue":"10","key":"10.1016\/j.mbs.2018.07.008_bib0127","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1507\/endocrj.EJ11-0037","article-title":"Predictive modeling of the hypothalamic-pituitary-adrenal (HPA) axis response to acute and chronic stress","volume":"58","author":"Markovic","year":"2011","journal-title":"Endocr. J."},{"issue":"6","key":"10.1016\/j.mbs.2018.07.008_bib0128","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pbio.1001341","article-title":"The origin of glucocorticoid hormone oscillations","volume":"10","author":"Walker","year":"2012","journal-title":"PLoS Biol."},{"issue":"1688","key":"10.1016\/j.mbs.2018.07.008_bib0129","doi-asserted-by":"crossref","first-page":"1627","DOI":"10.1098\/rspb.2009.2148","article-title":"Origin of ultradian pulsatility in the hypothalamic-pituitary-adrenal axis","volume":"277","author":"Walker","year":"2010","journal-title":"Proc. Biol. Sci."},{"issue":"2","key":"10.1016\/j.mbs.2018.07.008_bib0130","doi-asserted-by":"crossref","first-page":"e30978","DOI":"10.1371\/journal.pone.0030978","article-title":"Characterizing dynamic interactions between ultradian glucocorticoid rhythmicity and acute stress using the phase response curve","volume":"7","author":"Rankin","year":"2012","journal-title":"PLoS One"},{"issue":"3","key":"10.1016\/j.mbs.2018.07.008_bib0131","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.1002\/cphy.c140003","article-title":"HPA axis-rhythms","volume":"4","author":"Spiga","year":"2014","journal-title":"Compr. Physiol."},{"issue":"5881","key":"10.1016\/j.mbs.2018.07.008_bib0132","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1038\/299355a0","article-title":"Corticotropin releasing activity of the new CRF is potentiated several times by vasopressin","volume":"299","author":"Gillies","year":"1982","journal-title":"Nature"},{"issue":"Pt 2","key":"10.1016\/j.mbs.2018.07.008_bib0133","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1111\/j.1469-7793.1998.605bk.x","article-title":"The arginine vasopressin and corticotrophin-releasing hormone gene transcription responses to varied frequencies of repeated stress in rats","volume":"510","author":"Ma","year":"1998","journal-title":"J. Physiol."},{"issue":"8","key":"10.1016\/j.mbs.2018.07.008_bib0134","doi-asserted-by":"crossref","first-page":"3623","DOI":"10.1210\/endo.140.8.6943","article-title":"Vasopressin and corticotropin-releasing hormone gene responses to novel stress in rats adapted to repeated restraint","volume":"140","author":"Ma","year":"1999","journal-title":"Endocrinology"},{"issue":"3","key":"10.1016\/j.mbs.2018.07.008_bib0135","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1177\/0748730408316796","article-title":"A physiological model of a circannual oscillator","volume":"23","author":"Macgregor","year":"2008","journal-title":"J. Biol. Rhythms"},{"issue":"3","key":"10.1016\/j.mbs.2018.07.008_bib0136","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1210\/endo-98-3-696","article-title":"Termination at midpregnancy of the two daily surges of plasma prolactin initiated by mating in the rat","volume":"98","author":"Smith","year":"1976","journal-title":"Endocrinology"},{"issue":"3","key":"10.1016\/j.mbs.2018.07.008_bib0137","doi-asserted-by":"crossref","first-page":"E566","DOI":"10.1152\/ajpendo.00427.2005","article-title":"Prolactin secretory rhythm of mated rats induced by a single injection of oxytocin","volume":"290","author":"Egli","year":"2006","journal-title":"Am. J. Physiol. Endocrinol. Metab."},{"issue":"5","key":"10.1016\/j.mbs.2018.07.008_bib0138","doi-asserted-by":"crossref","first-page":"2159","DOI":"10.1210\/endo.140.5.6730","article-title":"Feedback effects of placental lactogens on prolactin levels and Fos-related antigen immunoreactivity of tuberoinfundibular dopaminergic neurons in the arcuate nucleus during pregnancy in the rat","volume":"140","author":"Lee","year":"1999","journal-title":"Endocrinology"},{"issue":"3","key":"10.1016\/j.mbs.2018.07.008_bib0139","doi-asserted-by":"crossref","first-page":"267","DOI":"10.33549\/physiolres.932301","article-title":"Dependence of spontaneous electrical activity and basal prolactin release on nonselective cation channels in pituitary lactotrophs","volume":"61","author":"Kucka","year":"2012","journal-title":"Physiol. Res."},{"issue":"3","key":"10.1016\/j.mbs.2018.07.008_bib0140","doi-asserted-by":"crossref","first-page":"E573","DOI":"10.1152\/ajpendo.00428.2005","article-title":"A mathematical model for the mating-induced prolactin rhythm of female rats","volume":"290","author":"Bertram","year":"2006","journal-title":"Am. J. Physiol. Endocrinol. Metab."},{"issue":"7","key":"10.1016\/j.mbs.2018.07.008_bib0141","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1111\/j.1365-2826.2010.02012.x","article-title":"A tale of two rhythms: the emerging roles of oxytocin in rhythmic prolactin release","volume":"22","author":"Bertram","year":"2010","journal-title":"J. Neuroendocrinol."},{"issue":"5","key":"10.1016\/j.mbs.2018.07.008_bib0142","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1530\/REP-10-0033","article-title":"Prolactin secretion patterns: basic mechanisms and clinical implications for reproduction","volume":"140","author":"Egli","year":"2010","journal-title":"Reproduction"},{"issue":"2","key":"10.1016\/j.mbs.2018.07.008_bib0143","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1007\/s10827-006-0008-4","article-title":"Low dose of dopamine may stimulate prolactin secretion by increasing fast potassium currents","volume":"22","author":"Tabak","year":"2007","journal-title":"J. Comput. Neurosci."},{"issue":"3","key":"10.1016\/j.mbs.2018.07.008_bib0144","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1007\/s10827-010-0226-7","article-title":"Mixed mode oscillations as a mechanism for pseudo-plateau bursting","volume":"28","author":"Vo","year":"2010","journal-title":"J. Comput. Neurosci."},{"key":"10.1016\/j.mbs.2018.07.008_bib0145","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/S0079-6123(01)33013-3","article-title":"Regulation of prolactin secretion during pregnancy and lactation","volume":"133","author":"Voogt","year":"2001","journal-title":"Prog. Brain Res."},{"issue":"10","key":"10.1016\/j.mbs.2018.07.008_bib0146","doi-asserted-by":"crossref","first-page":"4424","DOI":"10.1523\/JNEUROSCI.4415-12.2013","article-title":"Plasticity of hypothalamic dopamine neurons during lactation results in dissociation of electrical activity and release","volume":"33","author":"Romano","year":"2013","journal-title":"J. Neurosci."},{"key":"10.1016\/j.mbs.2018.07.008_bib0147","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1007\/978-3-319-12114-7_6","article-title":"Plasticity of the prolactin (PRL) axis: mechanisms underlying regulation of output in female mice","volume":"846","author":"Le Tissier","year":"2015","journal-title":"Adv. Exp. Med. Biol."},{"issue":"2","key":"10.1016\/j.mbs.2018.07.008_bib0148","doi-asserted-by":"crossref","first-page":"T101","DOI":"10.1530\/JOE-15-0213","article-title":"60 years of neuroendocrinology: the hypothalamo-prolactin axis","volume":"226","author":"Grattan","year":"2015","journal-title":"J. Endocrinol."},{"issue":"3","key":"10.1016\/j.mbs.2018.07.008_bib0149","doi-asserted-by":"crossref","first-page":"X3","DOI":"10.1530\/JOE-15-0124e","article-title":"60 years of neuroendocrinology: trh, the first hypophysiotropic releasing hormone isolated: control of the pituitary-thyroid axis","volume":"227","author":"Joseph-Bravo","year":"2015","journal-title":"J. Endocrinol."},{"issue":"2","key":"10.1016\/j.mbs.2018.07.008_bib0150","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/j.jtbi.2007.05.016","article-title":"A mathematical model of pituitary\u2013thyroid interaction to provide an insight into the nature of the thyrotropin\u2013thyroid hormone relationship","volume":"248","author":"Leow","year":"2007","journal-title":"J. Theor. Biol."},{"issue":"6","key":"10.1016\/j.mbs.2018.07.008_bib0151","doi-asserted-by":"crossref","first-page":"2300","DOI":"10.1210\/jc.2007-2674","article-title":"Free triiodothyronine has a distinct circadian rhythm that is delayed but parallels thyrotropin levels","volume":"93","author":"Russell","year":"2008","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.mbs.2018.07.008_bib0152","doi-asserted-by":"crossref","first-page":"91","DOI":"10.3389\/fendo.2018.00091","article-title":"Mathematical modeling of the pituitary-thyroid feedback loop: role of a tsh-t3-shunt and sensitivity analysis","volume":"9","author":"Berberich","year":"2018","journal-title":"Front Endocrinol. (Lausanne)"},{"issue":"2","key":"10.1016\/j.mbs.2018.07.008_bib0153","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1210\/jcem-70-2-403","article-title":"Physiological regulation of circadian and pulsatile thyrotropin secretion in normal man and woman","volume":"70","author":"Brabant","year":"1990","journal-title":"J. Clin. Endocrinol. Metab."},{"issue":"4","key":"10.1016\/j.mbs.2018.07.008_bib0154","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1007\/s11154-016-9375-y","article-title":"Advances in TRH signaling","volume":"17","author":"Joseph-Bravo","year":"2016","journal-title":"Rev. Endocr. Metab. Disord."},{"issue":"2","key":"10.1016\/j.mbs.2018.07.008_bib0155","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1210\/er.2013-1087","article-title":"Central regulation of hypothalamic-pituitary-thyroid axis under physiological and pathophysiological conditions","volume":"35","author":"Fekete","year":"2014","journal-title":"Endocr. Rev."},{"issue":"1","key":"10.1016\/j.mbs.2018.07.008_bib0156","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1038\/s41467-017-00604-6","article-title":"Tanycytes control the hormonal output of the hypothalamic-pituitary-thyroid axis","volume":"8","author":"Muller-Fielitz","year":"2017","journal-title":"Nat. Commun."},{"issue":"1","key":"10.1016\/j.mbs.2018.07.008_bib0157","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.ygcen.2012.02.002","article-title":"Endocrine archeology: do insects retain ancestrally inherited counterparts of the vertebrate releasing hormones GnRH, GHRH, TRH, and CRF?","volume":"177","author":"De Loof","year":"2012","journal-title":"Gen. Comp. Endocrinol."},{"issue":"25","key":"10.1016\/j.mbs.2018.07.008_bib0158","doi-asserted-by":"crossref","first-page":"11644","DOI":"10.1073\/pnas.0913798107","article-title":"Population robustness arising from cellular heterogeneity","volume":"107","author":"Paszek","year":"2010","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.mbs.2018.07.008_bib0159","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1113\/jphysiol.1988.sp017064","article-title":"Characteristics of early- and late-recruited oxytocin bursting cells at the beginning of suckling in rats","volume":"399","author":"Moos","year":"1988","journal-title":"J. Physiol."},{"issue":"1","key":"10.1016\/j.mbs.2018.07.008_bib0160","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1002\/cphy.c160007","article-title":"Dendritic release of neurotransmitters","volume":"7","author":"Ludwig","year":"2016","journal-title":"Compr. Physiol."},{"key":"10.1016\/j.mbs.2018.07.008_bib0161","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1113\/jphysiol.1986.sp016283","article-title":"Regulation of the milk ejection reflex in the rat","volume":"380","author":"Dyball","year":"1986","journal-title":"J. Physiol."}],"container-title":["Mathematical Biosciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0025556418302578?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0025556418302578?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,7,6]],"date-time":"2025-07-06T04:15:15Z","timestamp":1751775315000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0025556418302578"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,11]]},"references-count":161,"alternative-id":["S0025556418302578"],"URL":"https:\/\/doi.org\/10.1016\/j.mbs.2018.07.008","relation":{},"ISSN":["0025-5564"],"issn-type":[{"value":"0025-5564","type":"print"}],"subject":[],"published":{"date-parts":[[2018,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Models in neuroendocrinology","name":"articletitle","label":"Article Title"},{"value":"Mathematical Biosciences","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.mbs.2018.07.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Crown Copyright \u00a9 2018 Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}