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Cell Physiol."},{"key":"10.1016\/j.mce.2003.12.020_bib148","doi-asserted-by":"crossref","first-page":"1614","DOI":"10.1210\/me.6.10.1614","article-title":"The causal relationship between mutations in cAMP-dependent protein kinase and the loss of adrenocorticotropin-regulated adrenocortical functions","volume":"6","author":"Wong","year":"1992","journal-title":"Mol. Endocrinol."},{"key":"10.1016\/j.mce.2003.12.020_bib149","doi-asserted-by":"crossref","first-page":"12867","DOI":"10.1016\/S0021-9258(18)51567-2","article-title":"The roles of cAMP and cAMP-dependent protein kinase in the expression of cholesterol side chain cleavage and steroid 11 beta-hydroxylase genes in mouse adrenocortical tumor cells","volume":"264","author":"Wong","year":"1989","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.mce.2003.12.020_bib150","doi-asserted-by":"crossref","first-page":"4460","DOI":"10.1210\/jc.86.9.4460","article-title":"Expression and localization of human dopamine D2 and D4 receptor mRNA in the adrenal gland, aldosterone-producing adenoma, and pheochromocytoma","volume":"86","author":"Wu","year":"2001","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.mce.2003.12.020_bib151","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1093\/icb\/8.2.285","article-title":"Retention of differentiated function in clonal animal cell lines, particularly hormone-secreting cultures","author":"Yasumura","year":"1968","journal-title":"Am. Zoolog."},{"key":"10.1016\/j.mce.2003.12.020_bib152","first-page":"529","article-title":"Clonal analysis of differentiated function in animal cell cultures. I. 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