{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T00:17:22Z","timestamp":1789690642619,"version":"4.0.1"},"reference-count":27,"publisher":"Elsevier BV","issue":"1-2","license":[{"start":{"date-parts":[[2009,3,1]],"date-time":"2009-03-01T00:00:00Z","timestamp":1235865600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecular and Cellular Endocrinology"],"published-print":{"date-parts":[[2009,3]]},"DOI":"10.1016\/j.mce.2008.12.012","type":"journal-article","created":{"date-parts":[[2008,12,26]],"date-time":"2008-12-26T09:26:01Z","timestamp":1230283561000},"page":"104-108","source":"Crossref","is-referenced-by-count":66,"title":["Steroidogenic factor-1 and endometriosis"],"prefix":"10.1016","volume":"300","author":[{"given":"Serdar E.","family":"Bulun","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroki","family":"Utsunomiya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhihong","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ping","family":"Yin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"You-Hong","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary E.","family":"Pavone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideki","family":"Tokunaga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Trukhacheva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erkut","family":"Attar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bilgin","family":"Gurates","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Magdy P.","family":"Milad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edmond","family":"Confino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily","family":"Su","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott","family":"Reierstad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qing","family":"Xue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.mce.2008.12.012_bib1","doi-asserted-by":"crossref","first-page":"2131","DOI":"10.1016\/S0140-6736(02)09088-8","article-title":"Anastrozole alone or in combination with tamoxifen versus tamoxifen alone for adjuvant treatment of postmenopausal women with early breast cancer: first results of the ATAC randomised trial","volume":"359","author":"Baum","year":"2002","journal-title":"Lancet"},{"key":"10.1016\/j.mce.2008.12.012_bib2","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/S0304-3835(99)00050-6","article-title":"Correlation of aromatase and cyclooxygenase gene expression in human breast cancer specimens","author":"Brueggemeier","year":"1999","journal-title":"Cancer Lett."},{"key":"10.1016\/j.mce.2008.12.012_bib3","doi-asserted-by":"crossref","first-page":"2851","DOI":"10.1172\/JCI119478","article-title":"Suppression of matrix metalloproteinases inhibits establishment of ectopic lesions by human endometrium in nude mice","volume":"99","author":"Bruner","year":"1997","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.mce.2008.12.012_bib4","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1124\/pr.57.3.6","article-title":"Regulation of aromatase expression in estrogen-responsive breast and uterine disease: from bench to treatment","volume":"57","author":"Bulun","year":"2005","journal-title":"Pharmacol. Rev."},{"key":"10.1016\/j.mce.2008.12.012_bib5","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/S0960-0760(01)00134-0","article-title":"Role of aromatase in endometrial disease","volume":"79","author":"Bulun","year":"2001","journal-title":"J. Steroid Biochem. Mol. Biol."},{"key":"10.1016\/j.mce.2008.12.012_bib6","doi-asserted-by":"crossref","first-page":"3460","DOI":"10.1210\/jcem.87.7.8683","article-title":"Genetic or enzymatic disruption of aromatase inhibits the growth of ectopic uterine tissue","volume":"87","author":"Fang","year":"2002","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.mce.2008.12.012_bib7","doi-asserted-by":"crossref","first-page":"4369","DOI":"10.1210\/jc.2002-020522","article-title":"WT1 and DAX-1 inhibit aromatase P450 expression in human endometrial and endometriotic stromal cells","volume":"87","author":"Gurates","year":"2002","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.mce.2008.12.012_bib8","doi-asserted-by":"crossref","first-page":"13561","DOI":"10.1074\/jbc.270.22.13561","article-title":"Ad4BP\/SF-1 regulates cyclic AMP-induced transcription from the proximal promoter (PII) of the human aromatase P450 (CYP19) gene in the ovary","volume":"270","author":"Michael","year":"1995","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.mce.2008.12.012_bib9","first-page":"174","article-title":"Aromatase expression in endometriosis","volume":"81","author":"Noble","year":"1996","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.mce.2008.12.012_bib10","first-page":"600","article-title":"Prostaglandin E2 stimulates aromatase expression in endometriosis-derived stromal cells","volume":"82","author":"Noble","year":"1997","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.mce.2008.12.012_bib11","doi-asserted-by":"crossref","first-page":"1759","DOI":"10.1056\/NEJM199306173282407","article-title":"Endometriosis","volume":"328","author":"Olive","year":"1993","journal-title":"N Engl. J. Med."},{"key":"10.1016\/j.mce.2008.12.012_bib12","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1093\/humrep\/16.3.561","article-title":"Distribution of cyclooxygenase-2 in eutopic and ectopic endometrium in endometriosis and adenomyosis","volume":"16","author":"Ota","year":"2001","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.mce.2008.12.012_bib13","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1210\/edrv.18.3.0301","article-title":"Steroidogenic factor 1: a key determinant of endocrine development and function","volume":"18","author":"Parker","year":"1997","journal-title":"Endocrinol. Rev."},{"key":"10.1016\/j.mce.2008.12.012_bib14","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/S0960-0760(01)00187-X","article-title":"Signaling pathways regulating aromatase and cyclooxygenases in normal and malignant breast cells","volume":"80","author":"Richards","year":"2002","journal-title":"J. Steroid Biochem."},{"key":"10.1016\/j.mce.2008.12.012_bib15","first-page":"642","article-title":"Isolation, characterization, and comparison of human endometrial and endometriosis cells in vitro","volume":"78","author":"Ryan","year":"1994","journal-title":"J. Clin. Endo. Metab."},{"key":"10.1016\/j.mce.2008.12.012_bib16","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1097\/00006254-199706000-00021","article-title":"Endometriosis and infertility: new concepts","volume":"52","author":"Ryan","year":"1997","journal-title":"Obstet. Gynecol. Surv."},{"key":"10.1016\/j.mce.2008.12.012_bib17","doi-asserted-by":"crossref","first-page":"4600","DOI":"10.1210\/jcem.86.10.7947","article-title":"A highly complex organization of the regulatory region of the human CYP19 (aromatase) gene revealed by the human genome project","volume":"86","author":"Sebastian","year":"2001","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.mce.2008.12.012_bib18","doi-asserted-by":"crossref","first-page":"26208","DOI":"10.1074\/jbc.M201347200","article-title":"Up-regulation of cyclooxygenase-2 expression and prostaglandin synthesis in endometrial stromal cells by malignant endometrial epithelial cells. A paracrine effect mediated by prostaglandin E2 and nuclear factor-kappa B","volume":"277","author":"Tamura","year":"2002","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.mce.2008.12.012_bib19","first-page":"3263","article-title":"Interleukin-1beta elevates cyclooxygenase-2 protein level and enzyme activity via increasing its mRNA stability in human endometrial stromal cells: an effect mediated by extracellularly regulated kinase 1 and 2","volume":"87","author":"Tamura","year":"2002","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.mce.2008.12.012_bib20","doi-asserted-by":"crossref","first-page":"3504","DOI":"10.1210\/jcem.87.7.8796","article-title":"Vascular endothelial growth factor upregulates cyclooxygenase-2 expression in human endothelial cells","volume":"87","author":"Tamura","year":"2002","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.mce.2008.12.012_bib21","doi-asserted-by":"crossref","first-page":"5765","DOI":"10.1210\/jcem.86.12.8082","article-title":"Regulation of steroidogenic acute regulatory protein expression and progesterone production in endometriotic stromal cells","volume":"86","author":"Tsai","year":"2001","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.mce.2008.12.012_bib22","doi-asserted-by":"crossref","first-page":"904","DOI":"10.1210\/me.2006-0302","article-title":"Upstream stimulatory factor-2 regulates steroidogenic factor-1 expression in endometriosis","volume":"22","author":"Utsunomiya","year":"2008","journal-title":"Mol. Endocrinol."},{"key":"10.1016\/j.mce.2008.12.012_bib23","doi-asserted-by":"crossref","first-page":"3261","DOI":"10.1210\/jc.2007-0494","article-title":"Transcriptional activation of steroidogenic factor-1 by hypomethylation of the 5\u2032 CpG island in endometriosis","volume":"92","author":"Xue","year":"2007","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.mce.2008.12.012_bib24","first-page":"2336","article-title":"Regulation of aromatase P450 expression in endometriotic and endometrial stromal cells by CCAT\/enhancer binding proteins: decreased C\/EBPbeta in endometriosis is associated with over expression of aromatase","volume":"87","author":"Yang","year":"2002","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.mce.2008.12.012_bib25","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1016\/S0015-0282(99)00393-3","article-title":"Aromatase: a key molecule in the pathophysiology of endometriosis and a therapeutic target","volume":"72","author":"Zeitoun","year":"1999","journal-title":"Fertil Steril"},{"key":"10.1016\/j.mce.2008.12.012_bib26","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1210\/mend.13.2.0229","article-title":"Stimulation of aromatase P450 promoter (II) activity in endometriosis and its inhibition in endometrium are regulated by competitive binding of SF-1 and COUP-TF to the same cis-acting element","volume":"13","author":"Zeitoun","year":"1999","journal-title":"Mol. Endocrinol."},{"key":"10.1016\/j.mce.2008.12.012_bib27","first-page":"2328","article-title":"Malignant breast epithelial cells stimulate aromatase expression via promoter II in human adipose fibroblasts: an epithelial-stromal interaction in breast tumors mediated by CCAAT\/enhancer binding protein beta","volume":"61","author":"Zhou","year":"2001","journal-title":"Cancer Res."}],"container-title":["Molecular and Cellular Endocrinology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0303720708005649?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0303720708005649?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,12,23]],"date-time":"2018-12-23T09:55:11Z","timestamp":1545558911000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0303720708005649"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,3]]},"references-count":27,"journal-issue":{"issue":"1-2","published-print":{"date-parts":[[2009,3]]}},"alternative-id":["S0303720708005649"],"URL":"https:\/\/doi.org\/10.1016\/j.mce.2008.12.012","relation":{},"ISSN":["0303-7207"],"issn-type":[{"value":"0303-7207","type":"print"}],"subject":[],"published":{"date-parts":[[2009,3]]}}}