{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T01:27:55Z","timestamp":1791163675104,"version":"4.1.0"},"reference-count":167,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2010,3,1]],"date-time":"2010-03-01T00:00:00Z","timestamp":1267401600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecular and Cellular Endocrinology"],"published-print":{"date-parts":[[2010,3]]},"DOI":"10.1016\/j.mce.2009.06.010","type":"journal-article","created":{"date-parts":[[2009,6,28]],"date-time":"2009-06-28T08:12:23Z","timestamp":1246176743000},"page":"120-128","source":"Crossref","is-referenced-by-count":173,"title":["The role of gut hormones in the regulation of body weight and energy homeostasis"],"prefix":"10.1016","volume":"316","author":[{"given":"Efthimia","family":"Karra","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel L.","family":"Batterham","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.mce.2009.06.010_bib1","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/j.brainres.2005.02.065","article-title":"Blockade of the neuropeptide Y Y2 receptor with the specific antagonist BIIE0246 attenuates the effect of endogenous and exogenous peptide YY(3-36) on food intake","volume":"1043","author":"Abbott","year":"2005","journal-title":"Brain Res."},{"key":"10.1016\/j.mce.2009.06.010_bib2","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.brainres.2005.03.011","article-title":"The inhibitory effects of peripheral administration of peptide YY(3-36) and glucagon-like peptide-1 on food intake are attenuated by ablation of the vagal-brainstem-hypothalamic pathway","volume":"1044","author":"Abbott","year":"2005","journal-title":"Brain Res."},{"key":"10.1016\/j.mce.2009.06.010_bib3","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1038\/sj.ijo.0803137","article-title":"The importance of acclimatisation and habituation to experimental conditions when investigating the anorectic effects of gastrointestinal hormones in the rat","volume":"30","author":"Abbott","year":"2006","journal-title":"Int. J. Obes. (Lond.)"},{"key":"10.1016\/j.mce.2009.06.010_bib4","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1093\/jn\/136.1.195","article-title":"PYY[3\u201336] administration decreases the respiratory quotient and reduces adiposity in diet-induced obese mice","volume":"136","author":"Adams","year":"2006","journal-title":"J. Nutr."},{"key":"10.1016\/j.mce.2009.06.010_bib5","doi-asserted-by":"crossref","first-page":"1070","DOI":"10.1016\/0016-5085(85)90211-2","article-title":"Human distribution and release of a putative new gut hormone, peptide YY","volume":"89","author":"Adrian","year":"1985","journal-title":"Gastroenterology"},{"key":"10.1016\/j.mce.2009.06.010_bib6","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1381\/096089202321088084","article-title":"Peptide YY secretion in morbidly obese patients before and after vertical banded gastroplasty","volume":"12","author":"Alvarez Bartolome","year":"2002","journal-title":"Obes. Surg."},{"key":"10.1016\/j.mce.2009.06.010_bib7","doi-asserted-by":"crossref","first-page":"4753","DOI":"10.1210\/jc.86.10.4753","article-title":"Stomach is a major source of circulating ghrelin, and feeding state determines plasma ghrelin-like immunoreactivity levels in humans","volume":"86","author":"Ariyasu","year":"2001","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.mce.2009.06.010_bib8","first-page":"R1654","article-title":"Chronic infusion of islet amyloid polypeptide causes anorexia in rats","volume":"271","author":"Arnelo","year":"1996","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.mce.2009.06.010_bib9","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1159\/000054680","article-title":"A role of ghrelin in neuroendocrine and behavioral responses to stress in mice","volume":"74","author":"Asakawa","year":"2001","journal-title":"Neuroendocrinology"},{"key":"10.1016\/j.mce.2009.06.010_bib10","doi-asserted-by":"crossref","first-page":"1325","DOI":"10.1016\/S0016-5085(03)00216-6","article-title":"Characterization of the effects of pancreatic polypeptide in the regulation of energy balance","volume":"124","author":"Asakawa","year":"2003","journal-title":"Gastroenterology"},{"key":"10.1016\/j.mce.2009.06.010_bib11","doi-asserted-by":"crossref","first-page":"1501","DOI":"10.1111\/j.1440-1746.2006.04338.x","article-title":"Peptide YY3-36 and pancreatic polypeptide suppress food intake","volume":"21","author":"Asakawa","year":"2006","journal-title":"J. Gastroenterol. Hepatol."},{"key":"10.1016\/j.mce.2009.06.010_bib12","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1053\/j.gastro.2004.04.063","article-title":"Oxyntomodulin and glucagon-like peptide-1 differentially regulate murine food intake and energy expenditure","volume":"127","author":"Baggio","year":"2004","journal-title":"Gastroenterology"},{"key":"10.1016\/j.mce.2009.06.010_bib13","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/0014-5793(82)80709-6","article-title":"Isolation of glucagon-37 (bioactive enteroglucagon\/oxyntomodulin) from porcine jejuno-ileum. Characterization of the peptide","volume":"146","author":"Bataille","year":"1982","journal-title":"FEBS Lett."},{"key":"10.1016\/j.mce.2009.06.010_bib14","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1038\/nature00887","article-title":"Gut hormone PYY(3-36) physiologically inhibits food intake","volume":"418","author":"Batterham","year":"2002","journal-title":"Nature"},{"key":"10.1016\/j.mce.2009.06.010_bib15","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1056\/NEJMoa030204","article-title":"Inhibition of food intake in obese subjects by peptide YY3-36","volume":"349","author":"Batterham","year":"2003","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.mce.2009.06.010_bib16","doi-asserted-by":"crossref","first-page":"3989","DOI":"10.1210\/jc.2003-030630","article-title":"Pancreatic polypeptide reduces appetite and food intake in humans","volume":"88","author":"Batterham","year":"2003","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.mce.2009.06.010_bib17","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/j.cmet.2006.08.001","article-title":"Critical role for peptide YY in protein-mediated satiation and body-weight regulation","volume":"4","author":"Batterham","year":"2006","journal-title":"Cell Metab."},{"key":"10.1016\/j.mce.2009.06.010_bib18","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1038\/nature06212","article-title":"PYY modulation of cortical and hypothalamic brain areas predicts feeding behaviour in humans","volume":"450","author":"Batterham","year":"2007","journal-title":"Nature"},{"key":"10.1016\/j.mce.2009.06.010_bib19","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1177\/153537020322800301","article-title":"Recent developments in our understanding of the physiological role of PP-fold peptide receptor subtypes","volume":"228","author":"Berglund","year":"2003","journal-title":"Exp. Biol. Med. (Maywood)"},{"key":"10.1016\/j.mce.2009.06.010_bib20","doi-asserted-by":"crossref","first-page":"1680","DOI":"10.1096\/fj.04-3434fje","article-title":"Post-embryonic ablation of AgRP neurons in mice leads to a lean, hypophagic phenotype","volume":"19","author":"Bewick","year":"2005","journal-title":"FASEB J."},{"key":"10.1016\/j.mce.2009.06.010_bib21","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.peptides.2007.11.003","article-title":"PYY(3-36) induces Fos in the arcuate nucleus and in both catecholaminergic and non-catecholaminergic neurons in the nucleus tractus solitarius of rats","volume":"29","author":"Blevins","year":"2008","journal-title":"Peptides"},{"key":"10.1016\/j.mce.2009.06.010_bib22","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.npep.2007.11.003","article-title":"PYY transgenic mice are protected against diet-induced and genetic obesity","volume":"42","author":"Boey","year":"2008","journal-title":"Neuropeptides"},{"issue":"1","key":"10.1016\/j.mce.2009.06.010_bib23","doi-asserted-by":"crossref","first-page":"R29","DOI":"10.1152\/ajpregu.90706.2008","article-title":"Influence of resistance and aerobic exercise on hunger, circulating levels of acylated ghrelin, and peptide YY in healthy males","volume":"296","author":"Broom","year":"2008","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"10.1016\/j.mce.2009.06.010_bib24","doi-asserted-by":"crossref","first-page":"2534S","DOI":"10.1093\/jn\/137.11.2534S","article-title":"Glucagon-like peptide-1 and energy homeostasis","volume":"137","author":"Burcelin","year":"2007","journal-title":"J. Nutr."},{"key":"10.1016\/j.mce.2009.06.010_bib25","doi-asserted-by":"crossref","first-page":"752","DOI":"10.2337\/diabetes.39.6.752","article-title":"Effects of meal ingestion on plasma amylin concentration in NIDDM and nondiabetic humans","volume":"39","author":"Butler","year":"1990","journal-title":"Diabetes"},{"key":"10.1016\/j.mce.2009.06.010_bib26","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1002\/(SICI)1099-1387(200003)6:3<97::AID-PSC236>3.0.CO;2-E","article-title":"Molecular characterization of the ligand-receptor interaction of the neuropeptide Y family","volume":"6","author":"Cabrele","year":"2000","journal-title":"J. Pept. Sci."},{"key":"10.1016\/j.mce.2009.06.010_bib27","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1016\/j.bbrc.2003.10.089","article-title":"Acute effects of PYY3-36 on food intake and hypothalamic neuropeptide expression in the mouse","volume":"311","author":"Challis","year":"2003","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.mce.2009.06.010_bib28","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1038\/oby.2006.25","article-title":"Peptide YY levels are elevated after gastric bypass surgery","volume":"14","author":"Chan","year":"2006","journal-title":"Obesity (Silver Spring)"},{"issue":"7","key":"10.1016\/j.mce.2009.06.010_bib29","doi-asserted-by":"crossref","first-page":"2115","DOI":"10.1053\/j.gastro.2009.02.047","article-title":"Subject standardization, acclimatization, and sample processing affect gut hormone levels and appetite in humans","volume":"136","author":"Chandarana","year":"2009","journal-title":"Gastroenterology"},{"key":"10.1016\/j.mce.2009.06.010_bib30","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1007\/s00125-005-1732-4","article-title":"Effect of pramlintide on satiety and food intake in obese subjects and subjects with type 2 diabetes","volume":"48","author":"Chapman","year":"2005","journal-title":"Diabetologia"},{"key":"10.1016\/j.mce.2009.06.010_bib31","doi-asserted-by":"crossref","first-page":"R1064","DOI":"10.1152\/ajpregu.00376.2004","article-title":"Comparison of the inhibitory effects of PYY(3-36) and PYY(1-36) on gastric emptying in rats","volume":"287","author":"Chelikani","year":"2004","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"10.1016\/j.mce.2009.06.010_bib32","doi-asserted-by":"crossref","first-page":"R39","DOI":"10.1152\/ajpregu.00164.2007","article-title":"Intermittent intraperitoneal infusion of peptide YY(3-36) reduces daily food intake and adiposity in obese rats","volume":"293","author":"Chelikani","year":"2007","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"10.1016\/j.mce.2009.06.010_bib33","doi-asserted-by":"crossref","first-page":"2607","DOI":"10.1210\/en.2003-1596","article-title":"Orexigenic action of peripheral ghrelin is mediated by neuropeptide Y and agouti-related protein","volume":"145","author":"Chen","year":"2004","journal-title":"Endocrinology"},{"key":"10.1016\/j.mce.2009.06.010_bib34","doi-asserted-by":"crossref","first-page":"4696","DOI":"10.1210\/jc.2003-030421","article-title":"Oxyntomodulin suppresses appetite and reduces food intake in humans","volume":"88","author":"Cohen","year":"2003","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.mce.2009.06.010_bib35","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1210\/edrv-15-2-163","article-title":"Amylin compared with calcitonin gene-related peptide: structure, biology, and relevance to metabolic disease","volume":"15","author":"Cooper","year":"1994","journal-title":"Endocr. Rev."},{"key":"10.1016\/j.mce.2009.06.010_bib36","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1016\/S0896-6273(03)00063-1","article-title":"The distribution and mechanism of action of ghrelin in the CNS demonstrates a novel hypothalamic circuit regulating energy homeostasis","volume":"37","author":"Cowley","year":"2003","journal-title":"Neuron"},{"key":"10.1016\/j.mce.2009.06.010_bib37","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.physbeh.2006.05.022","article-title":"Ghrelin and the short- and long-term regulation of appetite and body weight","volume":"89","author":"Cummings","year":"2006","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.mce.2009.06.010_bib38","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1172\/JCI30227","article-title":"Gastrointestinal regulation of food intake","volume":"117","author":"Cummings","year":"2007","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.mce.2009.06.010_bib39","doi-asserted-by":"crossref","first-page":"1714","DOI":"10.2337\/diabetes.50.8.1714","article-title":"A preprandial rise in plasma ghrelin levels suggests a role in meal initiation in humans","volume":"50","author":"Cummings","year":"2001","journal-title":"Diabetes"},{"key":"10.1016\/j.mce.2009.06.010_bib40","doi-asserted-by":"crossref","first-page":"1623","DOI":"10.1056\/NEJMoa012908","article-title":"Plasma ghrelin levels after diet-induced weight loss or gastric bypass surgery","volume":"346","author":"Cummings","year":"2002","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.mce.2009.06.010_bib41","doi-asserted-by":"crossref","first-page":"E297","DOI":"10.1152\/ajpendo.00582.2003","article-title":"Plasma ghrelin levels and hunger scores in humans initiating meals voluntarily without time- and food-related cues","volume":"287","author":"Cummings","year":"2004","journal-title":"Am. J. Physiol. Endocrinol. Metab."},{"key":"10.1016\/j.mce.2009.06.010_bib42","doi-asserted-by":"crossref","first-page":"153","DOI":"10.2174\/1389450053174569","article-title":"Ghrelin and energy balance: focus on current controversies","volume":"6","author":"Cummings","year":"2005","journal-title":"Curr. Drug Targets"},{"key":"10.1016\/j.mce.2009.06.010_bib43","doi-asserted-by":"crossref","first-page":"4244","DOI":"10.1210\/en.142.10.4244","article-title":"Oxyntomodulin inhibits food intake in the rat","volume":"142","author":"Dakin","year":"2001","journal-title":"Endocrinology"},{"key":"10.1016\/j.mce.2009.06.010_bib44","doi-asserted-by":"crossref","first-page":"E1173","DOI":"10.1152\/ajpendo.00233.2002","article-title":"Repeated ICV administration of oxyntomodulin causes a greater reduction in body weight gain than in pair-fed rats","volume":"283","author":"Dakin","year":"2002","journal-title":"Am. J. Physiol. Endocrinol. Metab."},{"key":"10.1016\/j.mce.2009.06.010_bib45","doi-asserted-by":"crossref","first-page":"2687","DOI":"10.1210\/en.2003-1338","article-title":"Peripheral oxyntomodulin reduces food intake and body weight gain in rats","volume":"145","author":"Dakin","year":"2004","journal-title":"Endocrinology"},{"key":"10.1016\/j.mce.2009.06.010_bib46","doi-asserted-by":"crossref","first-page":"4255","DOI":"10.1210\/en.141.11.4255","article-title":"Ghrelin, a novel growth hormone-releasing acylated peptide, is synthesized in a distinct endocrine cell type in the gastrointestinal tracts of rats and humans","volume":"141","author":"Date","year":"2000","journal-title":"Endocrinology"},{"key":"10.1016\/j.mce.2009.06.010_bib47","doi-asserted-by":"crossref","first-page":"1120","DOI":"10.1053\/gast.2002.35954","article-title":"The role of the gastric afferent vagal nerve in ghrelin-induced feeding and growth hormone secretion in rats","volume":"123","author":"Date","year":"2002","journal-title":"Gastroenterology"},{"key":"10.1016\/j.mce.2009.06.010_bib48","doi-asserted-by":"crossref","first-page":"1430","DOI":"10.1053\/j.gastro.2005.09.001","article-title":"Effect of peptide YY3-36 on food intake in humans","volume":"129","author":"Degen","year":"2005","journal-title":"Gastroenterology"},{"key":"10.1016\/j.mce.2009.06.010_bib49","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1210\/en.138.2.771","article-title":"Induction of c-fos messenger ribonucleic acid in neuropeptide Y and growth hormone (GH)-releasing factor neurons in the rat arcuate nucleus following systemic injection of the GH secretagogue, GH-releasing peptide-6","volume":"138","author":"Dickson","year":"1997","journal-title":"Endocrinology"},{"key":"10.1016\/j.mce.2009.06.010_bib50","doi-asserted-by":"crossref","first-page":"1458","DOI":"10.1016\/j.metabol.2008.05.017","article-title":"Total peptide YY is a correlate of postprandial energy expenditure but not of appetite or energy intake in healthy women","volume":"57","author":"Doucet","year":"2008","journal-title":"Metabolism"},{"key":"10.1016\/j.mce.2009.06.010_bib51","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/S0196-9781(01)00601-5","article-title":"Distribution of pancreatic polypeptide and peptide YY","volume":"23","author":"Ekblad","year":"2002","journal-title":"Peptides"},{"key":"10.1016\/j.mce.2009.06.010_bib52","doi-asserted-by":"crossref","first-page":"4052","DOI":"10.1210\/jc.2006-2273","article-title":"Effect of macronutrient composition on postprandial peptide YY levels","volume":"92","author":"Essah","year":"2007","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.mce.2009.06.010_bib53","doi-asserted-by":"crossref","first-page":"1754","DOI":"10.1210\/jc.2006-1806","article-title":"Efficacy and safety of intranasal peptide YY3-36 for weight reduction in obese adults","volume":"92","author":"Gantz","year":"2007","journal-title":"J. Clin. Endocrinol. Metab."},{"issue":"Suppl. 2","key":"10.1016\/j.mce.2009.06.010_bib54","doi-asserted-by":"crossref","first-page":"S65","DOI":"10.1016\/S1262-3636(08)73397-4","article-title":"Physiology of incretins (GIP and GLP-1) and abnormalities in type 2 diabetes","volume":"34","author":"Gautier","year":"2008","journal-title":"Diabetes Metab."},{"key":"10.1016\/j.mce.2009.06.010_bib55","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1210\/jcem-57-3-488","article-title":"Molecular forms of human enteroglucagon in tissue and plasma: plasma responses to nutrient stimuli in health and in disorders of the upper gastrointestinal tract","volume":"57","author":"Ghatei","year":"1983","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.mce.2009.06.010_bib56","doi-asserted-by":"crossref","first-page":"11522","DOI":"10.1523\/JNEUROSCI.5405-06.2007","article-title":"Peptide YY3-36 decreases reinstatement of high-fat food seeking during dieting in a rat relapse model","volume":"27","author":"Ghitza","year":"2007","journal-title":"J. Neurosci."},{"key":"10.1016\/j.mce.2009.06.010_bib57","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.1016\/0026-0495(79)90129-X","article-title":"Effect of endurance exercise training on plasma pancreatic polypeptide concentration during exercise","volume":"28","author":"Gingerich","year":"1979","journal-title":"Metabolism"},{"key":"10.1016\/j.mce.2009.06.010_bib58","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1016\/j.diabet.2008.09.001","article-title":"The incretins: from the concept to their use in the treatment of type 2 diabetes. Part A: Incretins: concept and physiological functions","volume":"34","author":"Girard","year":"2008","journal-title":"Diabetes Metab."},{"key":"10.1016\/j.mce.2009.06.010_bib59","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1055\/s-2007-1010817","article-title":"Pancreatic polypeptide response to secretin in obesity: effects of glucose intolerance","volume":"20","author":"Glaser","year":"1988","journal-title":"Horm. Metab. Res."},{"key":"10.1016\/j.mce.2009.06.010_bib60","doi-asserted-by":"crossref","first-page":"2988","DOI":"10.1210\/jc.87.6.2988","article-title":"The tissue distribution of the mRNA of ghrelin and subtypes of its receptor, GHS-R, in humans","volume":"87","author":"Gnanapavan","year":"2002","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.mce.2009.06.010_bib61","doi-asserted-by":"crossref","first-page":"2811","DOI":"10.1016\/j.peptides.2006.07.012","article-title":"Lack of interaction between peripheral injection of CCK and obestatin in the regulation of gastric satiety signaling in rodents","volume":"27","author":"Gourcerol","year":"2006","journal-title":"Peptides"},{"key":"10.1016\/j.mce.2009.06.010_bib62","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/0167-0115(94)90204-6","article-title":"Two molecular forms of peptide YY (PYY) are abundant in human blood: characterization of a radioimmunoassay recognizing PYY 1-36 and PYY 3-36","volume":"51","author":"Grandt","year":"1994","journal-title":"Regul. Pept."},{"key":"10.1016\/j.mce.2009.06.010_bib63","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/S0169-328X(97)00071-5","article-title":"Distribution of mRNA encoding the growth hormone secretagogue receptor in brain and peripheral tissues","volume":"48","author":"Guan","year":"1997","journal-title":"Brain Res. Mol. Brain Res."},{"key":"10.1016\/j.mce.2009.06.010_bib64","doi-asserted-by":"crossref","first-page":"1562","DOI":"10.1038\/oby.2006.180","article-title":"Physiological evidence for the involvement of peptide YY in the regulation of energy homeostasis in humans","volume":"14","author":"Guo","year":"2006","journal-title":"Obesity (Silver Spring)"},{"key":"10.1016\/j.mce.2009.06.010_bib65","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.cmet.2005.02.003","article-title":"Peripheral administration of PYY(3-36) produces conditioned taste aversion in mice","volume":"1","author":"Halatchev","year":"2005","journal-title":"Cell Metab."},{"key":"10.1016\/j.mce.2009.06.010_bib66","doi-asserted-by":"crossref","first-page":"2585","DOI":"10.1210\/en.2003-1754","article-title":"Peptide YY3-36 inhibits food intake in mice through a melanocortin-4 receptor-independent mechanism","volume":"145","author":"Halatchev","year":"2004","journal-title":"Endocrinology"},{"key":"10.1016\/j.mce.2009.06.010_bib67","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1046\/j.0300-0664.2001.01456.x","article-title":"Weight loss increases circulating levels of ghrelin in human obesity","volume":"56","author":"Hansen","year":"2002","journal-title":"Clin. Endocrinol. (Oxf.)"},{"key":"10.1016\/j.mce.2009.06.010_bib68","doi-asserted-by":"crossref","first-page":"2225","DOI":"10.1210\/en.130.4.2225","article-title":"Autonomic nervous system mediation of the pancreatic polypeptide response to insulin-induced hypoglycemia in conscious rats","volume":"130","author":"Havel","year":"1992","journal-title":"Endocrinology"},{"key":"10.1016\/j.mce.2009.06.010_bib69","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1159\/000138122","article-title":"Variation of postprandial PYY 3-36 response following ingestion of differing macronutrient meals in obese females","volume":"52","author":"Helou","year":"2008","journal-title":"Ann. Nutr. Metab."},{"key":"10.1016\/j.mce.2009.06.010_bib70","doi-asserted-by":"crossref","first-page":"784","DOI":"10.2337\/diacare.26.3.784","article-title":"Pramlintide as an adjunct to insulin therapy improves long-term glycemic and weight control in patients with type 2 diabetes: a 1-year randomized controlled trial","volume":"26","author":"Hollander","year":"2003","journal-title":"Diabetes Care"},{"key":"10.1016\/j.mce.2009.06.010_bib71","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1038\/oby.2004.76","article-title":"Effect of pramlintide on weight in overweight and obese insulin-treated type 2 diabetes patients","volume":"12","author":"Hollander","year":"2004","journal-title":"Obes. Res."},{"key":"10.1016\/j.mce.2009.06.010_bib72","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1210\/en.2006-0933","article-title":"GPR39 signaling is stimulated by zinc ions but not by obestatin","volume":"148","author":"Holst","year":"2007","journal-title":"Endocrinology"},{"key":"10.1016\/j.mce.2009.06.010_bib73","doi-asserted-by":"crossref","first-page":"974","DOI":"10.1126\/science.273.5277.974","article-title":"A receptor in pituitary and hypothalamus that functions in growth hormone release","volume":"273","author":"Howard","year":"1996","journal-title":"Science"},{"key":"10.1016\/j.mce.2009.06.010_bib74","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1017\/S0007114507336799","article-title":"Low-dose pancreatic polypeptide inhibits food intake in man","volume":"97","author":"Jesudason","year":"2007","journal-title":"Br. J. Nutr."},{"key":"10.1016\/j.mce.2009.06.010_bib75","first-page":"393","article-title":"Fasting and postprandial plasma pancreatic polypeptide (PP) levels in obesity","volume":"8","author":"Jorde","year":"1984","journal-title":"Int. J. Obes."},{"key":"10.1016\/j.mce.2009.06.010_bib76","doi-asserted-by":"crossref","first-page":"4797","DOI":"10.1210\/en.141.12.4797","article-title":"Central effect of ghrelin, an endogenous growth hormone secretagogue, on hypothalamic peptide gene expression","volume":"141","author":"Kamegai","year":"2000","journal-title":"Endocrinology"},{"key":"10.1016\/j.mce.2009.06.010_bib77","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.1016\/0140-6736(92)90785-2","article-title":"Amylin concentrations and glucose control","volume":"339","author":"Koda","year":"1992","journal-title":"Lancet"},{"key":"10.1016\/j.mce.2009.06.010_bib78","doi-asserted-by":"crossref","first-page":"2369","DOI":"10.1210\/en.2004-1266","article-title":"The role of the vagal nerve in peripheral PYY3-36-induced feeding reduction in rats","volume":"146","author":"Koda","year":"2005","journal-title":"Endocrinology"},{"key":"10.1016\/j.mce.2009.06.010_bib79","doi-asserted-by":"crossref","first-page":"3198","DOI":"10.2337\/diabetes.54.11.3198","article-title":"Peptide YY(3-36) inhibits morning, but not evening, food intake and decreases body weight in rhesus macaques","volume":"54","author":"Koegler","year":"2005","journal-title":"Diabetes"},{"key":"10.1016\/j.mce.2009.06.010_bib80","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1152\/physrev.00012.2004","article-title":"Ghrelin: structure and function","volume":"85","author":"Kojima","year":"2005","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.mce.2009.06.010_bib81","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1038\/45230","article-title":"Ghrelin is a growth-hormone-releasing acylated peptide from stomach","volume":"402","author":"Kojima","year":"1999","journal-title":"Nature"},{"key":"10.1016\/j.mce.2009.06.010_bib82","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1016\/j.peptides.2006.09.024","article-title":"A role for pancreatic polypeptide in feeding and body weight regulation","volume":"28","author":"Kojima","year":"2007","journal-title":"Peptides"},{"key":"10.1016\/j.mce.2009.06.010_bib83","first-page":"G109","article-title":"Studies on the inhibition of pancreatic secretion by luminal somatostatin","volume":"241","author":"Konturek","year":"1981","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.mce.2009.06.010_bib84","doi-asserted-by":"crossref","first-page":"1553","DOI":"10.1038\/oby.2006.179","article-title":"Differential effects of gastric bypass and banding on circulating gut hormone and leptin levels","volume":"14","author":"Korner","year":"2006","journal-title":"Obesity (Silver Spring)"},{"key":"10.1016\/j.mce.2009.06.010_bib85","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/0167-0115(96)00110-3","article-title":"Structural diversity of receptors for neuropeptide Y, peptide YY and pancreatic polypeptide","volume":"65","author":"Larhammar","year":"1996","journal-title":"Regul. Pept."},{"key":"10.1016\/j.mce.2009.06.010_bib86","doi-asserted-by":"crossref","first-page":"428","DOI":"10.2337\/diabetes.29.6.428","article-title":"Low plasma levels of pancreatic polypeptide in obesity","volume":"29","author":"Lassmann","year":"1980","journal-title":"Diabetes"},{"key":"10.1016\/j.mce.2009.06.010_bib87","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1055\/s-2007-1013638","article-title":"Impaired pancreatic polypeptide response to insulin hypoglycemia in obese subjects","volume":"17","author":"Lassmann","year":"1985","journal-title":"Horm. Metab. Res."},{"key":"10.1016\/j.mce.2009.06.010_bib88","doi-asserted-by":"crossref","first-page":"1405","DOI":"10.1210\/jc.74.6.1405","article-title":"Oxyntomodulin-like immunoreactivity: diurnal profile of a new potential enterogastrone","volume":"74","author":"Le Quellec","year":"1992","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.mce.2009.06.010_bib89","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1097\/01.sla.0000183349.16877.84","article-title":"Gut hormone profiles following bariatric surgery favor an anorectic state, facilitate weight loss, and improve metabolic parameters","volume":"243","author":"le Roux","year":"2006","journal-title":"Ann. Surg."},{"key":"10.1016\/j.mce.2009.06.010_bib90","doi-asserted-by":"crossref","first-page":"385","DOI":"10.3109\/00365528309181611","article-title":"Pancreatic polypeptide release stimulated by food, secretin and cholecystokinin in chronic pancreatitis","volume":"18","author":"Linnestad","year":"1983","journal-title":"Scand. J. Gastroenterol."},{"key":"10.1016\/j.mce.2009.06.010_bib91","doi-asserted-by":"crossref","first-page":"1712","DOI":"10.1038\/ijo.2008.160","article-title":"The effects of pancreatic polypeptide on locomotor activity and food intake in mice","volume":"32","author":"Liu","year":"2008","journal-title":"Int. J. Obes. (Lond.)"},{"issue":"4","key":"10.1016\/j.mce.2009.06.010_bib92","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1016\/j.physbeh.2006.04.001","article-title":"Amylinergic control of food intake","volume":"89","author":"Lutz","year":"2006","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.mce.2009.06.010_bib93","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.1016\/0031-9384(95)02067-5","article-title":"Amylin decreases meal size in rats","volume":"58","author":"Lutz","year":"1995","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.mce.2009.06.010_bib94","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/S0196-9781(97)00292-1","article-title":"Lesion of the area postrema\/nucleus of the solitary tract (AP\/NTS) attenuates the anorectic effects of amylin and calcitonin gene-related peptide (CGRP) in rats","volume":"19","author":"Lutz","year":"1998","journal-title":"Peptides"},{"key":"10.1016\/j.mce.2009.06.010_bib95","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1038\/sj.ijo.0801664","article-title":"The anorectic effect of a chronic peripheral infusion of amylin is abolished in area postrema\/nucleus of the solitary tract (AP\/NTS) lesioned rats","volume":"25","author":"Lutz","year":"2001","journal-title":"Int. J. Obes. Relat. Metab. Disord."},{"key":"10.1016\/j.mce.2009.06.010_bib96","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1007\/BF01951279","article-title":"Pancreatic polypeptide: a possible role in the regulation of food intake in the mouse. Hypothesis","volume":"33","author":"Malaisse-Lagae","year":"1977","journal-title":"Experientia"},{"key":"10.1016\/j.mce.2009.06.010_bib97","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1016\/j.cmet.2008.03.007","article-title":"Ghrelin modulates brain activity in areas that control appetitive behavior","volume":"7","author":"Malik","year":"2008","journal-title":"Cell Metab."},{"key":"10.1016\/j.mce.2009.06.010_bib98","first-page":"173","article-title":"Changes in food preference, fat mass and energy expenditure with long term amylin treatment in rats","volume":"7","author":"Mark","year":"2006","journal-title":"Obes. Rev."},{"key":"10.1016\/j.mce.2009.06.010_bib99","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/0167-0115(93)90435-B","article-title":"Proteolytic processing of neuropeptide Y and peptide YY by dipeptidyl peptidase IV","volume":"49","author":"Mentlein","year":"1993","journal-title":"Regul. Pept."},{"key":"10.1016\/j.mce.2009.06.010_bib100","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1210\/jc.2005-1878","article-title":"Elevated peptide YY levels in adolescent girls with anorexia nervosa","volume":"91","author":"Misra","year":"2006","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.mce.2009.06.010_bib101","doi-asserted-by":"crossref","first-page":"1735","DOI":"10.1210\/jc.2005-0904","article-title":"Glucagon-like peptide-1, peptide YY, hunger, and satiety after gastric bypass surgery in morbidly obese subjects","volume":"91","author":"Morinigo","year":"2006","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.mce.2009.06.010_bib102","doi-asserted-by":"crossref","first-page":"1693","DOI":"10.1136\/gut.2005.069088","article-title":"Ghrelin enhances gastric emptying in diabetic gastroparesis: a double blind, placebo controlled, crossover study","volume":"54","author":"Murray","year":"2005","journal-title":"Gut"},{"key":"10.1016\/j.mce.2009.06.010_bib103","doi-asserted-by":"crossref","first-page":"2034","DOI":"10.1161\/hc4201.097836","article-title":"Elevated circulating level of ghrelin in cachexia associated with chronic heart failure: relationships between ghrelin and anabolic\/catabolic factors","volume":"104","author":"Nagaya","year":"2001","journal-title":"Circulation"},{"key":"10.1016\/j.mce.2009.06.010_bib104","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1016\/j.jpsychires.2006.07.021","article-title":"Incomplete restoration of the secretion of ghrelin and PYY compared to insulin after food ingestion following weight gain in anorexia nervosa","volume":"41","author":"Nakahara","year":"2007","journal-title":"J. Psychiatr. Res."},{"key":"10.1016\/j.mce.2009.06.010_bib105","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1038\/35051587","article-title":"A role for ghrelin in the central regulation of feeding","volume":"409","author":"Nakazato","year":"2001","journal-title":"Nature"},{"key":"10.1016\/j.mce.2009.06.010_bib106","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1038\/sj.ijo.0800418","article-title":"Gastrointestinal hormones and gastric emptying 20 years after jejunoileal bypass for massive obesity","volume":"21","author":"Naslund","year":"1997","journal-title":"Int. J. Obes. Relat. Metab. Disord."},{"key":"10.1016\/j.mce.2009.06.010_bib107","doi-asserted-by":"crossref","first-page":"2832","DOI":"10.1210\/jc.2003-031768","article-title":"Ghrelin increases energy intake in cancer patients with impaired appetite: acute, randomized, placebo-controlled trial","volume":"89","author":"Neary","year":"2004","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.mce.2009.06.010_bib108","doi-asserted-by":"crossref","first-page":"5120","DOI":"10.1210\/en.2005-0237","article-title":"Peptide YY3-36 and glucagon-like peptide-17-36 inhibit food intake additively","volume":"146","author":"Neary","year":"2005","journal-title":"Endocrinology"},{"key":"10.1016\/j.mce.2009.06.010_bib109","doi-asserted-by":"crossref","first-page":"1438","DOI":"10.1038\/ijo.2008.95","article-title":"No evidence of an additive inhibitory feeding effect following PP and PYY 3-36 administration","volume":"32","author":"Neary","year":"2008","journal-title":"Int. J. Obes. (Lond.)"},{"key":"10.1016\/j.mce.2009.06.010_bib110","doi-asserted-by":"crossref","first-page":"2255","DOI":"10.1210\/en.2004-0695","article-title":"Ingested medium-chain fatty acids are directly utilized for the acyl modification of ghrelin","volume":"146","author":"Nishi","year":"2005","journal-title":"Endocrinology"},{"key":"10.1016\/j.mce.2009.06.010_bib111","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1210\/en.2006-0915","article-title":"Effects of obestatin on energy balance and growth hormone secretion in rodents","volume":"148","author":"Nogueiras","year":"2007","journal-title":"Endocrinology"},{"key":"10.1016\/j.mce.2009.06.010_bib112","doi-asserted-by":"crossref","first-page":"948","DOI":"10.1124\/jpet.103.051821","article-title":"Characterization of blood\u2013brain barrier permeability to PYY3-36 in the mouse","volume":"306","author":"Nonaka","year":"2003","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.mce.2009.06.010_bib113","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1530\/EJE-1450669","article-title":"Weight gain decreases elevated plasma ghrelin concentrations of patients with anorexia nervosa","volume":"145","author":"Otto","year":"2001","journal-title":"Eur. J. Endocrinol."},{"key":"10.1016\/j.mce.2009.06.010_bib114","doi-asserted-by":"crossref","first-page":"1431","DOI":"10.1046\/j.1460-9568.1999.00553.x","article-title":"Regional distribution of Y-receptor subtype mRNAs in rat brain","volume":"11","author":"Parker","year":"1999","journal-title":"Eur. J. Neurosci."},{"issue":"3","key":"10.1016\/j.mce.2009.06.010_bib115","doi-asserted-by":"crossref","first-page":"1022","DOI":"10.1016\/j.neuroimage.2008.09.047","article-title":"Differential patterns of neuronal activation in the brainstem and hypothalamus following peripheral injection of GLP-1, oxyntomodulin and lithium chloride in mice detected by manganese-enhanced magnetic resonance imaging (MEMRI)","volume":"44","author":"Parkinson","year":"2008","journal-title":"Neuroimage"},{"key":"10.1016\/j.mce.2009.06.010_bib116","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1056\/NEJM199402033300503","article-title":"Islet amyloid polypeptide in patients with pancreatic cancer and diabetes","volume":"330","author":"Permert","year":"1994","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.mce.2009.06.010_bib117","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1210\/jc.2006-1425","article-title":"Effect of human body weight changes on circulating levels of peptide YY and peptide YY3-36","volume":"92","author":"Pfluger","year":"2007","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.mce.2009.06.010_bib118","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1038\/sj.ijo.0802696","article-title":"Effects of PYY[3\u201336] in rodent models of diabetes and obesity","volume":"28","author":"Pittner","year":"2004","journal-title":"Int. J. Obes. Relat. Metab. Disord."},{"key":"10.1016\/j.mce.2009.06.010_bib119","doi-asserted-by":"crossref","first-page":"4704","DOI":"10.1210\/en.2007-0107","article-title":"Decreased plasma peptide YY accompanied by elevated peptide YY and Y2 receptor binding densities in the medulla oblongata of diet-induced obese mice","volume":"148","author":"Rahardjo","year":"2007","journal-title":"Endocrinology"},{"key":"10.1016\/j.mce.2009.06.010_bib120","doi-asserted-by":"crossref","first-page":"4547","DOI":"10.1210\/jc.86.9.4547","article-title":"Plasma ghrelin concentration and energy balance: overfeeding and negative energy balance studies in twins","volume":"86","author":"Ravussin","year":"2001","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.mce.2009.06.010_bib121","doi-asserted-by":"crossref","first-page":"R114","DOI":"10.1152\/ajpregu.00333.2003","article-title":"The anorectic hormone amylin contributes to feeding-related changes of neuronal activity in key structures of the gut\u2013brain axis","volume":"286","author":"Riediger","year":"2004","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"10.1016\/j.mce.2009.06.010_bib122","doi-asserted-by":"crossref","first-page":"6386","DOI":"10.1210\/jc.2005-1357","article-title":"Peptide YY is a regulator of energy homeostasis in obese children before and after weight loss","volume":"90","author":"Roth","year":"2005","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.mce.2009.06.010_bib123","doi-asserted-by":"crossref","first-page":"6054","DOI":"10.1210\/en.2007-0898","article-title":"Combination therapy with amylin and peptide YY[3\u201336] in obese rodents: anorexigenic synergy and weight loss additivity","volume":"148","author":"Roth","year":"2007","journal-title":"Endocrinology"},{"key":"10.1016\/j.mce.2009.06.010_bib124","doi-asserted-by":"crossref","first-page":"7257","DOI":"10.1073\/pnas.0706473105","article-title":"Leptin responsiveness restored by amylin agonism in diet-induced obesity: evidence from nonclinical and clinical studies","volume":"105","author":"Roth","year":"2008","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.mce.2009.06.010_bib125","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/S0006-8993(98)01348-1","article-title":"Area postrema and the anorectic actions of dexfenfluramine and amylin","volume":"820","author":"Rowland","year":"1999","journal-title":"Brain Res."},{"key":"10.1016\/j.mce.2009.06.010_bib126","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1111\/j.1365-2826.2005.01330.x","article-title":"Intravenous peptide YY3-36 and Y2 receptor antagonism in the rat: effects on feeding behaviour","volume":"17","author":"Scott","year":"2005","journal-title":"J. Neuroendocrinol."},{"key":"10.1016\/j.mce.2009.06.010_bib127","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1016\/0306-4522(94)90388-3","article-title":"In vitro autoradiographic localization of amylin binding sites in rat brain","volume":"62","author":"Sexton","year":"1994","journal-title":"Neuroscience"},{"key":"10.1016\/j.mce.2009.06.010_bib128","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1210\/jc.87.1.240","article-title":"Plasma ghrelin levels in lean and obese humans and the effect of glucose on ghrelin secretion","volume":"87","author":"Shiiya","year":"2002","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.mce.2009.06.010_bib129","first-page":"774","article-title":"Increased plasma ghrelin level in lung cancer cachexia","volume":"9","author":"Shimizu","year":"2003","journal-title":"Clin. Cancer Res."},{"key":"10.1016\/j.mce.2009.06.010_bib130","doi-asserted-by":"crossref","first-page":"2131","DOI":"10.1373\/clinchem.2005.054908","article-title":"Circulating peptide YY concentrations are higher in preterm than full-term infants and correlate negatively with body weight and positively with serum ghrelin concentrations","volume":"51","author":"Siahanidou","year":"2005","journal-title":"Clin. Chem."},{"key":"10.1016\/j.mce.2009.06.010_bib131","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1056\/NEJMoa066254","article-title":"Effects of bariatric surgery on mortality in Swedish obese subjects","volume":"357","author":"Sjostrom","year":"2007","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.mce.2009.06.010_bib132","doi-asserted-by":"crossref","first-page":"E1062","DOI":"10.1152\/ajpendo.00450.2006","article-title":"Effects of PYY1-36 and PYY3-36 on appetite, energy intake, energy expenditure, glucose and fat metabolism in obese and lean subjects","volume":"292","author":"Sloth","year":"2007","journal-title":"Am. J. Physiol. Endocrinol. Metab."},{"key":"10.1016\/j.mce.2009.06.010_bib133","doi-asserted-by":"crossref","first-page":"E620","DOI":"10.1152\/ajpendo.00217.2007","article-title":"Pramlintide treatment reduces 24-h caloric intake and meal sizes and improves control of eating in obese subjects: a 6-wk translational research study","volume":"293","author":"Smith","year":"2007","journal-title":"Am. J. Physiol. Endocrinol. Metab."},{"issue":"Suppl. 1","key":"10.1016\/j.mce.2009.06.010_bib134","first-page":"37","article-title":"Basal and postprandial gut peptides affecting food intake in lean and obese pregnant women","volume":"58","author":"Sodowski","year":"2007","journal-title":"J. Physiol. Pharmacol."},{"key":"10.1016\/j.mce.2009.06.010_bib135","doi-asserted-by":"crossref","first-page":"R962","DOI":"10.1152\/ajpregu.00405.2006","article-title":"Oxyntomodulin increases intrinsic heart rate in mice independent of the glucagon-like peptide-1 receptor","volume":"292","author":"Sowden","year":"2007","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"10.1016\/j.mce.2009.06.010_bib136","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/j.physbeh.2007.08.018","article-title":"Peptide YY levels are associated with appetite suppression in response to long-chain fatty acids","volume":"93","author":"Stoeckel","year":"2008","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.mce.2009.06.010_bib137","doi-asserted-by":"crossref","first-page":"4679","DOI":"10.1073\/pnas.0305930101","article-title":"Ghrelin stimulation of growth hormone release and appetite is mediated through the growth hormone secretagogue receptor","volume":"101","author":"Sun","year":"2004","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.mce.2009.06.010_bib138","doi-asserted-by":"crossref","first-page":"3748","DOI":"10.1210\/en.2005-0473","article-title":"Peripheral exendin-4 and peptide YY(3-36) synergistically reduce food intake through different mechanisms in mice","volume":"146","author":"Talsania","year":"2005","journal-title":"Endocrinology"},{"key":"10.1016\/j.mce.2009.06.010_bib139","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1038\/285417a0","article-title":"Isolation of two novel candidate hormones using a chemical method for finding naturally occurring polypeptides","volume":"285","author":"Tatemoto","year":"1980","journal-title":"Nature"},{"key":"10.1016\/j.mce.2009.06.010_bib140","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1210\/en.2003-0899","article-title":"Ghrelin and des-octanoyl ghrelin promote adipogenesis directly in vivo by a mechanism independent of the type 1a growth hormone secretagogue receptor","volume":"145","author":"Thompson","year":"2004","journal-title":"Endocrinology"},{"key":"10.1016\/j.mce.2009.06.010_bib141","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1210\/jc.2002-020645","article-title":"Balance in ghrelin and leptin plasma levels in anorexia nervosa patients and constitutionally thin women","volume":"88","author":"Tolle","year":"2003","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.mce.2009.06.010_bib142","doi-asserted-by":"crossref","first-page":"1484","DOI":"10.1139\/y80-223","article-title":"Human pancreatic polypeptide: studies of fasting and postprandial plasma concentrations","volume":"58","author":"Track","year":"1980","journal-title":"Can. J. Physiol. Pharmacol."},{"key":"10.1016\/j.mce.2009.06.010_bib143","doi-asserted-by":"crossref","first-page":"5679","DOI":"10.1210\/en.2008-0770","article-title":"Amylin-mediated restoration of leptin responsiveness in diet-induced obesity: magnitude and mechanisms","volume":"149","author":"Trevaskis","year":"2008","journal-title":"Endocrinology"},{"key":"10.1016\/j.mce.2009.06.010_bib144","doi-asserted-by":"crossref","first-page":"908","DOI":"10.1038\/35038090","article-title":"Ghrelin induces adiposity in rodents","volume":"407","author":"Tschop","year":"2000","journal-title":"Nature"},{"key":"10.1016\/j.mce.2009.06.010_bib145","doi-asserted-by":"crossref","first-page":"707","DOI":"10.2337\/diabetes.50.4.707","article-title":"Circulating ghrelin levels are decreased in human obesity","volume":"50","author":"Tschop","year":"2001","journal-title":"Diabetes"},{"key":"10.1016\/j.mce.2009.06.010_bib146","doi-asserted-by":"crossref","first-page":"3739","DOI":"10.1210\/jc.2003-032118","article-title":"Malignant gastric ghrelinoma with hyperghrelinemia","volume":"89","author":"Tsolakis","year":"2004","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.mce.2009.06.010_bib147","doi-asserted-by":"crossref","first-page":"1427","DOI":"10.1016\/S0016-5085(99)70293-3","article-title":"Decreased food intake and body weight in pancreatic polypeptide-overexpressing mice","volume":"117","author":"Ueno","year":"1999","journal-title":"Gastroenterology"},{"key":"10.1016\/j.mce.2009.06.010_bib148","doi-asserted-by":"crossref","first-page":"R51","DOI":"10.1152\/ajpregu.00234.2007","article-title":"Leptin extends the anorectic effects of chronic PYY(3-36) administration in ad libitum-fed rats","volume":"295","author":"Unniappan","year":"2008","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"10.1016\/j.mce.2009.06.010_bib149","doi-asserted-by":"crossref","first-page":"1915","DOI":"10.1007\/s00125-006-0310-8","article-title":"Effects of dipeptidyl peptidase IV on the satiety actions of peptide YY","volume":"49","author":"Unniappan","year":"2006","journal-title":"Diabetologia"},{"key":"10.1016\/j.mce.2009.06.010_bib150","doi-asserted-by":"crossref","first-page":"E238","DOI":"10.1152\/ajpendo.00239.2006","article-title":"Chronic PYY3-36 treatment promotes fat oxidation and ameliorates insulin resistance in C57BL6 mice","volume":"292","author":"van den Hoek","year":"2007","journal-title":"Am. J. Physiol. Endocrinol. Metab."},{"key":"10.1016\/j.mce.2009.06.010_bib151","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1210\/er.2002-0029","article-title":"Biological, physiological, pathophysiological, and pharmacological aspects of ghrelin","volume":"25","author":"van der Lely","year":"2004","journal-title":"Endocr. Rev."},{"key":"10.1016\/j.mce.2009.06.010_bib152","doi-asserted-by":"crossref","first-page":"R367","DOI":"10.1152\/ajpregu.00726.2005","article-title":"PYY(3-36) reduces food intake and body weight and improves insulin sensitivity in rodent models of diet-induced obesity","volume":"291","author":"Vrang","year":"2006","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"10.1016\/j.mce.2009.06.010_bib153","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1111\/j.1463-1326.2007.00807.x","article-title":"Co-administration of SR141716 with peptide YY3-36 or oxyntomodulin has additive effects on food intake in mice","volume":"10","author":"White","year":"2008","journal-title":"Diabetes Obes. Metab."},{"key":"10.1016\/j.mce.2009.06.010_bib154","doi-asserted-by":"crossref","first-page":"3573","DOI":"10.1172\/JCI26003","article-title":"Absence of ghrelin protects against early-onset obesity","volume":"115","author":"Wortley","year":"2005","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.mce.2009.06.010_bib155","doi-asserted-by":"crossref","first-page":"1534","DOI":"10.1053\/j.gastro.2007.08.024","article-title":"Peptide YY regulates bone turnover in rodents","volume":"133","author":"Wortley","year":"2007","journal-title":"Gastroenterology"},{"key":"10.1016\/j.mce.2009.06.010_bib156","doi-asserted-by":"crossref","first-page":"4325","DOI":"10.1210\/en.141.11.4325","article-title":"The novel hypothalamic peptide ghrelin stimulates food intake and growth hormone secretion","volume":"141","author":"Wren","year":"2000","journal-title":"Endocrinology"},{"key":"10.1016\/j.mce.2009.06.010_bib157","doi-asserted-by":"crossref","first-page":"2540","DOI":"10.2337\/diabetes.50.11.2540","article-title":"Ghrelin causes hyperphagia and obesity in rats","volume":"50","author":"Wren","year":"2001","journal-title":"Diabetes"},{"key":"10.1016\/j.mce.2009.06.010_bib158","doi-asserted-by":"crossref","first-page":"2390","DOI":"10.2337\/diabetes.54.8.2390","article-title":"Subcutaneous oxyntomodulin reduces body weight in overweight and obese subjects: a double-blind, randomized, controlled trial","volume":"54","author":"Wynne","year":"2005","journal-title":"Diabetes"},{"key":"10.1016\/j.mce.2009.06.010_bib159","doi-asserted-by":"crossref","first-page":"2111","DOI":"10.1681\/ASN.2005010039","article-title":"Subcutaneous ghrelin enhances acute food intake in malnourished patients who receive maintenance peritoneal dialysis: a randomized, placebo-controlled trial","volume":"16","author":"Wynne","year":"2005","journal-title":"J. Am. Soc. Nephrol."},{"key":"10.1016\/j.mce.2009.06.010_bib160","doi-asserted-by":"crossref","first-page":"1729","DOI":"10.1038\/sj.ijo.0803344","article-title":"Oxyntomodulin increases energy expenditure in addition to decreasing energy intake in overweight and obese humans: a randomised controlled trial","volume":"30","author":"Wynne","year":"2006","journal-title":"Int. J. Obes. (Lond.)"},{"key":"10.1016\/j.mce.2009.06.010_bib161","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1007\/BF02828131","article-title":"Interaction of dietary composition and PYY gene expression in diet-induced obesity in rats","volume":"25","author":"Yang","year":"2005","journal-title":"J. Huazhong Univ. Sci. Technol. Med. Sci."},{"key":"10.1016\/j.mce.2009.06.010_bib162","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1002\/(SICI)1098-2299(199604)37:4<231::AID-DDR5>3.0.CO;2-M","article-title":"Preclinical pharmacology of pramlitidine in the rat:comparisons with human and rat amylin","volume":"37","author":"Young","year":"1996","journal-title":"Drug Dev. Res."},{"key":"10.1016\/j.mce.2009.06.010_bib163","doi-asserted-by":"crossref","first-page":"996","DOI":"10.1126\/science.1117255","article-title":"Obestatin, a peptide encoded by the ghrelin gene, opposes ghrelin's effects on food intake","volume":"310","author":"Zhang","year":"2005","journal-title":"Science"},{"key":"10.1016\/j.mce.2009.06.010_bib164","doi-asserted-by":"crossref","first-page":"3564","DOI":"10.1172\/JCI26002","article-title":"Mice lacking ghrelin receptors resist the development of diet-induced obesity","volume":"115","author":"Zigman","year":"2005","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.mce.2009.06.010_bib165","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1002\/cne.20823","article-title":"Expression of ghrelin receptor mRNA in the rat and the mouse brain","volume":"494","author":"Zigman","year":"2006","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.mce.2009.06.010_bib166","doi-asserted-by":"crossref","first-page":"1264","DOI":"10.1210\/jcem-52-6-1264","article-title":"Blunted pancreatic polypeptide responses in children with obesity of Prader-Willi syndrome","volume":"52","author":"Zipf","year":"1981","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.mce.2009.06.010_bib167","doi-asserted-by":"crossref","first-page":"13226","DOI":"10.1073\/pnas.0605376103","article-title":"Vaccination against weight gain","volume":"103","author":"Zorrilla","year":"2006","journal-title":"Proc. Natl. Acad. Sci. U.S.A."}],"container-title":["Molecular and Cellular Endocrinology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0303720709003463?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0303720709003463?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,3,14]],"date-time":"2024-03-14T22:39:35Z","timestamp":1710455975000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0303720709003463"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,3]]},"references-count":167,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2010,3]]}},"alternative-id":["S0303720709003463"],"URL":"https:\/\/doi.org\/10.1016\/j.mce.2009.06.010","relation":{},"ISSN":["0303-7207"],"issn-type":[{"value":"0303-7207","type":"print"}],"subject":[],"published":{"date-parts":[[2010,3]]}}}