{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,7,5]],"date-time":"2024-07-05T09:48:40Z","timestamp":1720172920813},"reference-count":62,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"FoRum","award":["F735-2011"],"award-info":[{"award-number":["F735-2011"]}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Molecular and Cellular Endocrinology"],"published-print":{"date-parts":[[2015,9]]},"DOI":"10.1016\/j.mce.2015.05.013","type":"journal-article","created":{"date-parts":[[2015,5,18]],"date-time":"2015-05-18T06:05:18Z","timestamp":1431929118000},"page":"272-280","update-policy":"http:\/\/dx.doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["NCI-H295R cell line as in vitro model of hyperaldosteronism lacks functional KCNJ5 (GIRK4; Kir3.4) channels"],"prefix":"10.1016","volume":"412","author":[{"given":"Marie-C\u00e9cile","family":"Kienitz","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Evanthia","family":"Mergia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lutz","family":"Pott","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.mce.2015.05.013_bib0010","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1111\/j.1471-4159.2007.05153.x","article-title":"Cell type-specific subunit composition of G protein-gated potassium channels in the cerebellum","volume":"105","author":"Aguado","year":"2008","journal-title":"J. Neurochem"},{"issue":"8","key":"10.1016\/j.mce.2015.05.013_bib0015","doi-asserted-by":"crossref","first-page":"988","DOI":"10.1038\/nn.2358","article-title":"A discrete alcohol pocket involved in GIRK channel activation","volume":"12","author":"Aryal","year":"2009","journal-title":"Nat. Neurosci"},{"issue":"4","key":"10.1016\/j.mce.2015.05.013_bib0020","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1159\/000129381","article-title":"G protein-activated (GIRK) current in rat ventricular myocytes is masked by constitutive inward rectifier current (IK1)","volume":"21","author":"Beckmann","year":"2008","journal-title":"Cell. Physiol. Biochem"},{"issue":"31","key":"10.1016\/j.mce.2015.05.013_bib0025","doi-asserted-by":"crossref","first-page":"28873","DOI":"10.1074\/jbc.M102328200","article-title":"Overexpression of monomeric and multimeric GIRK4 subunits in rat atrial myocytes removes fast desensitization and reduces inward rectification of muscarinic K+ current (IK(ACh)). Evidence for functional homomeric GIRK4 channels","volume":"276","author":"Bender","year":"2001","journal-title":"J. Biol. Chem"},{"issue":"4","key":"10.1016\/j.mce.2015.05.013_bib0030","doi-asserted-by":"crossref","first-page":"1555","DOI":"10.1210\/endo.133.4.8404594","article-title":"Human NCI-H295 adrenocortical carcinoma cells: a model for angiotensin-II-responsive aldosterone secretion","volume":"133","author":"Bird","year":"1993","journal-title":"Endocrinology"},{"issue":"6","key":"10.1016\/j.mce.2015.05.013_bib0035","doi-asserted-by":"crossref","first-page":"E1480","DOI":"10.1152\/ajpendo.90652.2008","article-title":"Both TASK-3 and TREK-1 two-pore loop K channels are expressed in H295R cells and modulate their membrane potential and aldosterone secretion","volume":"295","author":"Brenner","year":"2008","journal-title":"Am. J. Physiol. Endocrinol. Metab"},{"issue":"Pt 2","key":"10.1016\/j.mce.2015.05.013_bib0040","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1113\/jphysiol.1996.sp021497","article-title":"Downregulation of muscarinic M2 receptors linked to K+ current in cultured guinea-pig atrial myocytes","volume":"494","author":"B\u00fcnemann","year":"1996","journal-title":"J. Physiol"},{"issue":"1","key":"10.1016\/j.mce.2015.05.013_bib0045","doi-asserted-by":"crossref","first-page":"E155","DOI":"10.1210\/jc.2014-3009","article-title":"Novel KCNJ5 mutations in sporadic aldosterone-producing adenoma reduce Kir3.4 membrane abundance","volume":"100","author":"Cheng","year":"2015","journal-title":"J. Clin. Endocrinol. Metab"},{"issue":"6018","key":"10.1016\/j.mce.2015.05.013_bib0050","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1126\/science.1198785","article-title":"K+ channel mutations in adrenal aldosterone-producing adenomas and hereditary hypertension","volume":"331","author":"Choi","year":"2011","journal-title":"Science"},{"issue":"1","key":"10.1016\/j.mce.2015.05.013_bib0055","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1007\/s002329900340","article-title":"Activation by angiotensin II of Ca2+-dependent K+ and Cl- currents in zona fasciculata cells of bovine adrenal gland","volume":"162","author":"Chorvatova","year":"1998","journal-title":"J. Membr. Biol"},{"issue":"42","key":"10.1016\/j.mce.2015.05.013_bib0060","doi-asserted-by":"crossref","first-page":"27499","DOI":"10.1074\/jbc.273.42.27499","article-title":"Identification of native atrial G-protein-regulated inwardly rectifying K+ (GIRK4) channel homomultimers","volume":"273","author":"Corey","year":"1998","journal-title":"J. Biol. Chem"},{"issue":"9","key":"10.1016\/j.mce.2015.05.013_bib0065","doi-asserted-by":"crossref","first-page":"5271","DOI":"10.1074\/jbc.273.9.5271","article-title":"Number and stoichiometry of subunits in the native atrial G-protein-gated K+ channel, IKACh","volume":"273","author":"Corey","year":"1998","journal-title":"J. Biol. Chem"},{"issue":"3","key":"10.1016\/j.mce.2015.05.013_bib0070","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1210\/mend.16.3.0788","article-title":"TASK-3 dominates the background potassium conductance in rat adrenal glomerulosa cells","volume":"16","author":"Czirj\u00e1k","year":"2002","journal-title":"Mol. Endocrinol"},{"issue":"6","key":"10.1016\/j.mce.2015.05.013_bib0075","first-page":"863","article-title":"TASK (TWIK-related acid-sensitive K+ channel) is expressed in glomerulosa cells of rat adrenal cortex and inhibited by angiotensin II","volume":"14","author":"Czirj\u00e1k","year":"2000","journal-title":"Mol. Endocrinol"},{"issue":"6","key":"10.1016\/j.mce.2015.05.013_bib0080","doi-asserted-by":"crossref","first-page":"2203","DOI":"10.1073\/pnas.0712000105","article-title":"TASK channel deletion in mice causes primary hyperaldosteronism","volume":"105","author":"Davies","year":"2008","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"issue":"5360","key":"10.1016\/j.mce.2015.05.013_bib0085","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1126\/science.280.5360.69","article-title":"The structure of the potassium channel: molecular basis of K+ conduction and selectivity","volume":"280","author":"Doyle","year":"1998","journal-title":"Science"},{"issue":"3","key":"10.1016\/j.mce.2015.05.013_bib0090","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1124\/mol.109.061861","article-title":"cAMP analogs and their metabolites enhance TREK-1 mRNA and K+ current expression in adrenocortical cells","volume":"77","author":"Enyeart","year":"2010","journal-title":"Mol. Pharmacol"},{"issue":"51","key":"10.1016\/j.mce.2015.05.013_bib0095","doi-asserted-by":"crossref","first-page":"49186","DOI":"10.1074\/jbc.M207233200","article-title":"An ACTH- and ATP-regulated background K+ channel in adrenocortical cells is TREK-1","volume":"277","author":"Enyeart","year":"2002","journal-title":"J. Biol. Chem"},{"issue":"3","key":"10.1016\/j.mce.2015.05.013_bib0100","doi-asserted-by":"crossref","first-page":"C619","DOI":"10.1152\/ajpcell.00117.2011","article-title":"Calcium-dependent inhibition of adrenal TREK-1 channels by angiotensin II and ionomycin","volume":"301","author":"Enyeart","year":"2011","journal-title":"Am. J. Physiol. Cell Physiol"},{"issue":"33","key":"10.1016\/j.mce.2015.05.013_bib0105","doi-asserted-by":"crossref","first-page":"10129","DOI":"10.1021\/bi060509s","article-title":"Characterization of Kir1.1 channels with the use of a radiolabeled derivative of tertiapin","volume":"45","author":"Felix","year":"2006","journal-title":"Biochemistry"},{"key":"10.1016\/j.mce.2015.05.013_bib0110","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1016\/j.mce.2015.01.020","article-title":"Functional histopathological markers of aldosterone producing adenoma and somatic KCNJ5 mutations","volume":"408","author":"Fernandes-Rosa","year":"2015","journal-title":"Mol. Cell. Endocrinol"},{"issue":"9","key":"10.1016\/j.mce.2015.05.013_bib0115","doi-asserted-by":"crossref","first-page":"3266","DOI":"10.1210\/jc.2008-0104","article-title":"Case detection, diagnosis, and treatment of patients with primary aldosteronism: an endocrine society clinical practice guideline","volume":"93","author":"Funder","year":"2008","journal-title":"J. Clin. Endocrinol. Metab"},{"issue":"1","key":"10.1016\/j.mce.2015.05.013_bib0120","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1210\/en.2013-1733","article-title":"Minireview: potassium channels and aldosterone dysregulation: is primary aldosteronism a potassium channelopathy?","volume":"155","author":"Gomez-Sanchez","year":"2014","journal-title":"Endocrinology"},{"issue":"10","key":"10.1016\/j.mce.2015.05.013_bib0125","doi-asserted-by":"crossref","first-page":"987","DOI":"10.2174\/1389201015666141031111916","article-title":"G protein-coupled receptor signaling to Kir channels in Xenopus oocytes","volume":"15","author":"Hatcher-Solis","year":"2014","journal-title":"Curr. Pharm. Biotechnol"},{"issue":"2","key":"10.1016\/j.mce.2015.05.013_bib0130","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.mce.2011.07.034","article-title":"Acute and chronic regulation of aldosterone production","volume":"350","author":"Hattangady","year":"2012","journal-title":"Mol. Cell. Endocrinol"},{"issue":"1","key":"10.1016\/j.mce.2015.05.013_bib0135","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1152\/physrev.00021.2009","article-title":"Inwardly rectifying potassium channels: their structure, function, and physiological roles","volume":"90","author":"Hibino","year":"2010","journal-title":"Physiol. Rev"},{"issue":"3","key":"10.1016\/j.mce.2015.05.013_bib0140","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1007\/s10529-008-9882-3","article-title":"Generation of a stable mammalian cell line for simultaneous expression of multiple genes by using 2A peptide-based lentiviral vector","volume":"31","author":"Hu","year":"2009","journal-title":"Biotechnol. Lett"},{"issue":"1","key":"10.1016\/j.mce.2015.05.013_bib0145","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1113\/jphysiol.1994.sp020111","article-title":"Background conductance attributable to spontaneous opening of muscarinic K+ channels in rabbit sino-atrial node cells","volume":"476","author":"Ito","year":"1994","journal-title":"J. Physiol"},{"issue":"43","key":"10.1016\/j.mce.2015.05.013_bib0150","doi-asserted-by":"crossref","first-page":"14286","DOI":"10.1021\/bi991205r","article-title":"Synthesis of a stable form of tertiapin: a high-affinity inhibitor for inward-rectifier K+ channels","volume":"38","author":"Jin","year":"1999","journal-title":"Biochemistry"},{"issue":"Pt 24","key":"10.1016\/j.mce.2015.05.013_bib0155","doi-asserted-by":"crossref","first-page":"5373","DOI":"10.1113\/jphysiol.2014.283218","article-title":"Recruitment of G\u03b2\u03b3 controls the basal activity of G-protein coupled inwardly rectifying potassium (GIRK) channels: crucial role of distal C terminus of GIRK1","volume":"592","author":"Kahanovitch","year":"2014","journal-title":"J. Physiol"},{"issue":"4","key":"10.1016\/j.mce.2015.05.013_bib0160","doi-asserted-by":"crossref","first-page":"2571","DOI":"10.1074\/jbc.274.4.2571","article-title":"GIRK4 confers appropriate processing and cell surface localization to G-protein-gated potassium channels","volume":"274","author":"Kennedy","year":"1999","journal-title":"J. Biol. Chem"},{"issue":"6","key":"10.1016\/j.mce.2015.05.013_bib0165","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1007\/s00395-011-0193-9","article-title":"Remodeling of inward rectifying K+ currents in rat atrial myocytes by overexpression of A1-adenosine receptors","volume":"106","author":"Kienitz","year":"2011","journal-title":"Basic Res. Cardiol"},{"issue":"6","key":"10.1016\/j.mce.2015.05.013_bib0170","doi-asserted-by":"crossref","first-page":"1182","DOI":"10.1016\/j.cellsig.2014.02.007","article-title":"Differential effects of genetically-encoded G\u03b2\u03b3 scavengers on receptor-activated and basal Kir3.1\/Kir3.4 channel current in rat atrial myocytes","volume":"26","author":"Kienitz","year":"2014","journal-title":"Cell. Signal"},{"issue":"6518","key":"10.1016\/j.mce.2015.05.013_bib0175","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1038\/374135a0","article-title":"The G-protein-gated atrial K+ channel IKACh is a heteromultimer of two inwardly rectifying K+-channel proteins","volume":"374","author":"Krapivinsky","year":"1995","journal-title":"Nature"},{"issue":"3","key":"10.1016\/j.mce.2015.05.013_bib0180","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1007\/BF00585301","article-title":"On the mechanism of activation of muscarinic K+ channels by adenosine in isolated atrial cells: involvement of GTP-binding proteins","volume":"407","author":"Kurachi","year":"1986","journal-title":"Pfl\u00fcgers Arch"},{"issue":"2","key":"10.1016\/j.mce.2015.05.013_bib0185","first-page":"124","article-title":"Characterization of NCI-H295R cells as an in vitro model of hyperaldosteronism","volume":"45","author":"Lichtenauer","year":"2013","journal-title":"Horm. Metab. Res"},{"issue":"10","key":"10.1016\/j.mce.2015.05.013_bib0190","doi-asserted-by":"crossref","first-page":"4167","DOI":"10.1210\/endo.138.10.5463","article-title":"Effects of K+ channel blockers on K+ channels, membrane potential, and aldosterone secretion in rat adrenal zona glomerulosa cells","volume":"138","author":"Lotshaw","year":"1997","journal-title":"Endocrinology"},{"issue":"5","key":"10.1016\/j.mce.2015.05.013_bib0195","doi-asserted-by":"crossref","first-page":"1236","DOI":"10.1038\/nprot.2007.135","article-title":"A protocol for rapid generation of recombinant adenoviruses using the AdEasy system","volume":"2","author":"Luo","year":"2007","journal-title":"Nat. Protoc"},{"issue":"5","key":"10.1016\/j.mce.2015.05.013_bib0200","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1038\/nrn2834","article-title":"Emerging roles for G protein-gated inwardly rectifying potassium (GIRK) channels in health and disease","volume":"11","author":"L\u00fcscher","year":"2010","journal-title":"Nat. Rev. Neurosci"},{"issue":"28","key":"10.1016\/j.mce.2015.05.013_bib0205","doi-asserted-by":"crossref","first-page":"19943","DOI":"10.1074\/jbc.274.28.19943","article-title":"Angiotensin II negatively modulates L-type calcium channels through a pertussis toxin-sensitive G protein in adrenal glomerulosa cells","volume":"274","author":"Maturana","year":"1999","journal-title":"J. Biol. Chem"},{"issue":"Pt 1","key":"10.1016\/j.mce.2015.05.013_bib0210","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1113\/jphysiol.2007.140772","article-title":"Generation of a constitutive Na+-dependent inward-rectifier current in rat adult atrial myocytes by overexpression of Kir3.4","volume":"585","author":"Mintert","year":"2007","journal-title":"J. Physiol"},{"issue":"11","key":"10.1016\/j.mce.2015.05.013_bib0215","doi-asserted-by":"crossref","first-page":"E1861","DOI":"10.1210\/jc.2013-2428","article-title":"a Novel Y152C KCNJ5 mutation responsible for familial hyperaldosteronism type III","volume":"98","author":"Monticone","year":"2013","journal-title":"J. Clin. Endocrinol. Metab"},{"key":"10.1016\/j.mce.2015.05.013_bib0220","first-page":"1","article-title":"Gene mutations that promote adrenal aldosterone production, sodium retention, and hypertension","volume":"7","author":"Moraitis","year":"2013","journal-title":"Appl. Clin. Genet"},{"issue":"2","key":"10.1016\/j.mce.2015.05.013_bib0225","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1038\/nrendo.2012.230","article-title":"Role of KCNJ5 in familial and sporadic primary aldosteronism","volume":"9","author":"Mulatero","year":"2013","journal-title":"Nat. Rev. Endocrinol"},{"issue":"9","key":"10.1016\/j.mce.2015.05.013_bib0230","doi-asserted-by":"crossref","first-page":"1827","DOI":"10.1097\/HJH.0b013e328356139f","article-title":"Characterization of a novel somatic KCNJ5 mutation delI157 in an aldosterone-producing adenoma","volume":"30","author":"Murthy","year":"2012","journal-title":"J. Hypertens"},{"issue":"4","key":"10.1016\/j.mce.2015.05.013_bib0235","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1161\/HYPERTENSIONAHA.113.02234","article-title":"Role for germline mutations and a rare coding single nucleotide polymorphism within the KCNJ5 potassium channel in a large cohort of sporadic cases of primary aldosteronism","volume":"63","author":"Murthy","year":"2014","journal-title":"Hypertension"},{"issue":"9","key":"10.1016\/j.mce.2015.05.013_bib0240","doi-asserted-by":"crossref","first-page":"4328","DOI":"10.1210\/en.2012-1241","article-title":"The potassium channel, Kir3.4 participates in angiotensin II-stimulated aldosterone production by a human adrenocortical cell line","volume":"153","author":"Oki","year":"2012","journal-title":"Endocrinology"},{"issue":"10","key":"10.1016\/j.mce.2015.05.013_bib0245","doi-asserted-by":"crossref","first-page":"4740","DOI":"10.1210\/en.2012-1527","article-title":"Task3 potassium channel gene invalidation causes low renin and salt-sensitive arterial hypertension","volume":"153","author":"Penton","year":"2012","journal-title":"Endocrinology"},{"issue":"1\u20132","key":"10.1016\/j.mce.2015.05.013_bib0250","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.mce.2003.12.020","article-title":"Adrenocortical cell lines","volume":"228","author":"Rainey","year":"2004","journal-title":"Mol. Cell. Endocrinol"},{"issue":"6","key":"10.1016\/j.mce.2015.05.013_bib0255","doi-asserted-by":"crossref","first-page":"3840","DOI":"10.1074\/jbc.C200605200","article-title":"Na+ promotes the dissociation between G\u03b1GDP and G\u03b2\u03b3, activating G protein-gated K+ channels","volume":"278","author":"Rishal","year":"2003","journal-title":"J. Biol. Chem"},{"issue":"Pt 14","key":"10.1016\/j.mce.2015.05.013_bib0260","doi-asserted-by":"crossref","first-page":"3473","DOI":"10.1113\/jphysiol.2009.173229","article-title":"Divergent regulation of GIRK1 and GIRK2 subunits of the neuronal G protein gated K+ channel by G\u03b1iGDP and G\u03b2\u03b3","volume":"587","author":"Rubinstein","year":"2009","journal-title":"J. Physiol"},{"issue":"5914","key":"10.1016\/j.mce.2015.05.013_bib0265","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1038\/303250a0","article-title":"Acetylcholine activation of single muscarinic K+ channels in isolated pacemaker cells of the mammalian heart","volume":"303","author":"Sakmann","year":"1983","journal-title":"Nature"},{"issue":"7","key":"10.1016\/j.mce.2015.05.013_bib0270","doi-asserted-by":"crossref","first-page":"2533","DOI":"10.1073\/pnas.1121407109","article-title":"Hypertension with or without adrenal hyperplasia due to different inherited mutations in the potassium channel KCNJ5","volume":"109","author":"Scholl","year":"2012","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"issue":"3","key":"10.1016\/j.mce.2015.05.013_bib0275","doi-asserted-by":"crossref","first-page":"1307","DOI":"10.1073\/pnas.95.3.1307","article-title":"Activation of the atrial KACh channel by the \u03b2\u03b3 subunits of G proteins or intracellular Na+ ions depends on the presence of phosphatidylinositol phosphates","volume":"95","author":"Sui","year":"1998","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"issue":"4","key":"10.1016\/j.mce.2015.05.013_bib0280","doi-asserted-by":"crossref","first-page":"1353","DOI":"10.1210\/en.2013-1944","article-title":"Pharmacology and pathophysiology of mutated KCNJ5 found in adrenal aldosterone-producing adenomas","volume":"155","author":"Tauber","year":"2014","journal-title":"Endocrinology"},{"issue":"4","key":"10.1016\/j.mce.2015.05.013_bib0285","doi-asserted-by":"crossref","first-page":"1214","DOI":"10.1016\/j.bbamem.2012.12.016","article-title":"Molecular basis of the facilitation of the heterooligomeric GIRK1\/GIRK4 complex by cAMP dependent protein kinase","volume":"1828","author":"Treiber","year":"2013","journal-title":"Biochim. Biophys. Acta"},{"issue":"6","key":"10.1016\/j.mce.2015.05.013_bib0290","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1161\/01.RES.86.6.643","article-title":"Overexpressed A1 adenosine receptors reduce activation of acetylcholine-sensitive K+ current by native muscarinic M2 receptors in rat atrial myocytes","volume":"86","author":"Wellner-Kienitz","year":"2000","journal-title":"Circ. Res"},{"issue":"Pt 2","key":"10.1016\/j.mce.2015.05.013_bib0295","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1113\/jphysiol.2002.023093","article-title":"GABAB receptor activation desensitizes postsynaptic GABAB and A1 adenosine responses in rat hippocampal neurones","volume":"544","author":"Wetherington","year":"2002","journal-title":"J. Physiol"},{"issue":"1","key":"10.1016\/j.mce.2015.05.013_bib0300","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/j.cell.2011.07.046","article-title":"Crystal structure of the mammalian GIRK2 K+ channel and gating regulation by G proteins, PIP2, and sodium","volume":"147","author":"Whorton","year":"2011","journal-title":"Cell"},{"issue":"4","key":"10.1016\/j.mce.2015.05.013_bib0305","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1016\/j.neuron.2006.03.046","article-title":"Modulation of basal and receptor-induced GIRK potassium channel activity and neuronal excitability by the mammalian PINS homolog LGN","volume":"50","author":"Wiser","year":"2006","journal-title":"Neuron"},{"issue":"2","key":"10.1016\/j.mce.2015.05.013_bib0310","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1124\/jpet.300.2.681","article-title":"The role of muscarinic K+ channels in the negative chronotropic effect of a muscarinic agonist","volume":"300","author":"Yamada","year":"2002","journal-title":"J. Pharmacol. Exp. Ther"},{"issue":"1","key":"10.1016\/j.mce.2015.05.013_bib0315","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.neuroscience.2007.01.061","article-title":"Localization of the pannexin1 protein at postsynaptic sites in the cerebral cortex and hippocampus","volume":"146","author":"Zoidl","year":"2007","journal-title":"Neuroscience"}],"container-title":["Molecular and Cellular Endocrinology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0303720715002713?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0303720715002713?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,6,9]],"date-time":"2024-06-09T01:54:00Z","timestamp":1717898040000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0303720715002713"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,9]]},"references-count":62,"alternative-id":["S0303720715002713"],"URL":"https:\/\/doi.org\/10.1016\/j.mce.2015.05.013","relation":{},"ISSN":["0303-7207"],"issn-type":[{"value":"0303-7207","type":"print"}],"subject":[],"published":{"date-parts":[[2015,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"NCI-H295R cell line as in vitro model of hyperaldosteronism lacks functional KCNJ5 (GIRK4; Kir3.4) channels","name":"articletitle","label":"Article Title"},{"value":"Molecular and Cellular Endocrinology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.mce.2015.05.013","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier Ireland Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}