{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T10:58:58Z","timestamp":1776855538001,"version":"3.51.2"},"reference-count":57,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,11,1]],"date-time":"2018-11-01T00:00:00Z","timestamp":1541030400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,11,1]],"date-time":"2018-11-01T00:00:00Z","timestamp":1541030400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100006310","name":"Swedish Research Council","doi-asserted-by":"publisher","award":["521-2012-2119"],"award-info":[{"award-number":["521-2012-2119"]}],"id":[{"id":"10.13039\/501100006310","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006310","name":"Swedish Research Council","doi-asserted-by":"publisher","award":["522-2008-4216"],"award-info":[{"award-number":["522-2008-4216"]}],"id":[{"id":"10.13039\/501100006310","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006310","name":"Swedish Research Council","doi-asserted-by":"publisher","award":["K2009-55X 21111-01-4"],"award-info":[{"award-number":["K2009-55X 21111-01-4"]}],"id":[{"id":"10.13039\/501100006310","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006310","name":"Swedish Research Council","doi-asserted-by":"publisher","award":["2017-00862"],"award-info":[{"award-number":["2017-00862"]}],"id":[{"id":"10.13039\/501100006310","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Lund University Diabetes Centre","award":["349-2008-6589"],"award-info":[{"award-number":["349-2008-6589"]}]},{"name":"The Novo Nordisk Foundation"},{"name":"The Royal Physiographic Society in Lund"},{"DOI":"10.13039\/501100004817","name":"The medical faculty at Lund University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004817","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006189","name":"Crafoord and Albert P\u00e5hlsson Foundations","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006189","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Molecular and Cellular Endocrinology"],"published-print":{"date-parts":[[2018,11]]},"DOI":"10.1016\/j.mce.2018.04.002","type":"journal-article","created":{"date-parts":[[2018,4,6]],"date-time":"2018-04-06T07:54:24Z","timestamp":1523001264000},"page":"8-16","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":11,"special_numbering":"C","title":["Intestinal CART is a regulator of GIP and GLP-1 secretion and expression"],"prefix":"10.1016","volume":"476","author":[{"given":"L.","family":"Shcherbina","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Lindqvist","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.-H.","family":"Thor\u00e9n Fischer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Ahlqvist","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.E.","family":"Falkmer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Renstr\u00f6m","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Koffert","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Honka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.","family":"Wierup","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.mce.2018.04.002_bib1","series-title":"51st Annual Meeting of the European-association-for-the-study-of-diabetes (EASD), SEP 14-18, 2015, Stockholm, Sweden, Diabetologia","first-page":"S279","article-title":"CART is a novel glucose-dependent peptide with antidiabetic actions in humans","author":"Abels","year":"2015"},{"key":"10.1016\/j.mce.2018.04.002_bib2","doi-asserted-by":"crossref","first-page":"1928","DOI":"10.1007\/s00125-016-4020-6","article-title":"CART is overexpressed in human type 2 diabetic islets and inhibits glucagon secretion and increases insulin secretion","volume":"59","author":"Abels","year":"2016","journal-title":"Diabetologia"},{"key":"10.1016\/j.mce.2018.04.002_bib3","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1111\/j.1439-0264.2008.00893.x","article-title":"Immunodetection of cocaine- and amphetamine-regulated transcript in the rumen, reticulum, omasum and abomasum of the sheep","volume":"38","author":"Arciszewski","year":"2009","journal-title":"Anat. Histol. Embryol."},{"key":"10.1016\/j.mce.2018.04.002_bib4","doi-asserted-by":"crossref","first-page":"4394","DOI":"10.1210\/endo.142.10.8416","article-title":"Absence of cocaine- and amphetamine-regulated transcript results in obesity in mice fed a high caloric diet","volume":"142","author":"Asnicar","year":"2001","journal-title":"Endocrinology"},{"key":"10.1016\/j.mce.2018.04.002_bib5","doi-asserted-by":"crossref","first-page":"2131","DOI":"10.1053\/j.gastro.2007.03.054","article-title":"Biology of incretins: GLP-1 and GIP","volume":"132","author":"Baggio","year":"2007","journal-title":"Gastroenterology"},{"key":"10.1016\/j.mce.2018.04.002_bib6","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.regpep.2012.12.011","article-title":"Cocaine- and amphetamine-regulated transcript is expressed in adipocytes and regulate lipid- and glucose homeostasis","volume":"182","author":"Banke","year":"2013","journal-title":"Regul. Pept."},{"key":"10.1016\/j.mce.2018.04.002_bib7","doi-asserted-by":"crossref","first-page":"1246","DOI":"10.1210\/jc.2007-1946","article-title":"Elevated cocaine- and amphetamine-regulated transcript immunoreactivity in the circulation of patients with neuroendocrine malignancy","volume":"93","author":"Bech","year":"2008","journal-title":"J. Clin. Endocrinol. Metabol."},{"key":"10.1016\/j.mce.2018.04.002_bib8","doi-asserted-by":"crossref","first-page":"17438","DOI":"10.1074\/jbc.272.28.17438","article-title":"Cell-specific expression of the glucose-dependent insulinotropic polypeptide gene in a mouse neuroendocrine tumor cell line","volume":"272","author":"Boylan","year":"1997","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.mce.2018.04.002_bib9","doi-asserted-by":"crossref","first-page":"15007","DOI":"10.1074\/jbc.M212128200","article-title":"Biological processing of the cocaine and amphetamine-regulated transcript precursors by prohormone convertases, PC2 and PC1\/3","volume":"278","author":"Dey","year":"2003","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.mce.2018.04.002_bib10","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.cmet.2006.01.004","article-title":"The biology of incretin hormones","volume":"3","author":"Drucker","year":"2006","journal-title":"Cell Metabol."},{"key":"10.1016\/j.mce.2018.04.002_bib11","doi-asserted-by":"crossref","first-page":"1926","DOI":"10.1016\/j.peptides.2005.10.025","article-title":"The activity of CART peptide fragments","volume":"27","author":"Dylag","year":"2006","journal-title":"Peptides"},{"key":"10.1016\/j.mce.2018.04.002_bib12","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1046\/j.1365-2982.2003.00437.x","article-title":"Cocaine- and amphetamine-regulated transcript: distribution and function in rat gastrointestinal tract","volume":"15","author":"Ekblad","year":"2003","journal-title":"Neuro Gastroenterol. Motil."},{"key":"10.1016\/j.mce.2018.04.002_bib13","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1007\/s00441-002-0678-9","article-title":"Distribution and chemical coding of cocaine- and amphetamine-regulated transcript peptide (CART)-immunoreactive neurons in the Guinea pig bowel","volume":"312","author":"Ellis","year":"2003","journal-title":"Cell Tissue Res."},{"key":"10.1016\/j.mce.2018.04.002_bib14","doi-asserted-by":"crossref","first-page":"1966","DOI":"10.1053\/j.gastro.2010.01.049","article-title":"Glucose-dependent insulinotropic polypeptide is expressed in pancreatic islet alpha-cells and promotes insulin secretion","volume":"138","author":"Fujita","year":"2010","journal-title":"Gastroenterology"},{"key":"10.1016\/j.mce.2018.04.002_bib15","doi-asserted-by":"crossref","first-page":"S251","DOI":"10.2337\/dc11-s227","article-title":"Loss of incretin effect is a specific, important, and early characteristic of type 2 diabetes","volume":"34","author":"Holst","year":"2011","journal-title":"Diabetes Care"},{"key":"10.1016\/j.mce.2018.04.002_bib16","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1677\/JOE-08-0085","article-title":"Mechanisms underlying proglucagon gene expression","volume":"198","author":"Jin","year":"2008","journal-title":"J. Endocrinol."},{"key":"10.1016\/j.mce.2018.04.002_bib17","first-page":"419","article-title":"Cocaine- and amphetamine-regulated transcript : identification and distribution in human gastrointestinal tract","volume":"26","author":"Kasacka","year":"2012","journal-title":"J. Biol. Regul. Homeost. Agents"},{"key":"10.1016\/j.mce.2018.04.002_bib18","first-page":"E316","article-title":"Gastric inhibitory polypeptide release from a tumor-derived cell line","volume":"269","author":"Kieffer","year":"1995","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.mce.2018.04.002_bib19","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1046\/j.1365-2826.1997.00651.x","article-title":"Immunohistochemical localization of novel CART peptides in rat hypothalamus, pituitary and adrenal gland","volume":"9","author":"Koylu","year":"1997","journal-title":"J. Neuroendocrinol."},{"key":"10.1016\/j.mce.2018.04.002_bib20","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1038\/29993","article-title":"Hypothalamic CART is a new anorectic peptide regulated by leptin","volume":"393","author":"Kristensen","year":"1998","journal-title":"Nature"},{"key":"10.1016\/j.mce.2018.04.002_bib21","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0167-0115(00)00096-3","article-title":"CART peptides","volume":"89","author":"Kuhar","year":"2000","journal-title":"Regul. Pept."},{"key":"10.1016\/j.mce.2018.04.002_bib22","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1016\/j.neulet.2005.04.072","article-title":"Cocaine- and amphetamine-regulated transcript (CART) peptide activates the extracellular signal-regulated kinase (ERK) pathway in AtT20 cells via putative G-protein coupled receptors","volume":"384","author":"Lakatos","year":"2005","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.mce.2018.04.002_bib23","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1159\/000329044","article-title":"Cocaine- and amphetamine-regulated transcript in neuroendocrine tumors","volume":"94","author":"Landerholm","year":"2011","journal-title":"Neuroendocrinology"},{"key":"10.1016\/j.mce.2018.04.002_bib24","doi-asserted-by":"crossref","first-page":"10705","DOI":"10.1016\/S0021-9258(19)50075-8","article-title":"Glucagon gene 5'-flanking sequences direct expression of simian virus 40 large T antigen to the intestine, producing carcinoma of the large bowel in transgenic mice","volume":"267","author":"Lee","year":"1992","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.mce.2018.04.002_bib25","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/S0167-0115(03)00125-3","article-title":"GLP-1 and GIP are colocalized in a subset of endocrine cells in the small intestine","volume":"114","author":"Mortensen","year":"2003","journal-title":"Regul. Pept."},{"key":"10.1016\/j.mce.2018.04.002_bib26","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1172\/JCI116186","article-title":"Preserved incretin activity of glucagon-like peptide 1 [7-36 amide] but not of synthetic human gastric inhibitory polypeptide in patients with type-2 diabetes mellitus","volume":"91","author":"Nauck","year":"1993","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.mce.2018.04.002_bib27","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1007\/BF00401145","article-title":"Normalization of fasting hyperglycaemia by exogenous glucagon-like peptide 1 (7-36 amide) in type 2 (non-insulin-dependent) diabetic patients","volume":"36","author":"Nauck","year":"1993","journal-title":"Diabetologia"},{"key":"10.1016\/j.mce.2018.04.002_bib28","doi-asserted-by":"crossref","first-page":"1237","DOI":"10.1016\/j.soard.2015.03.021","article-title":"Mucosal glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide cell numbers in the super-obese human foregut after gastric bypass","volume":"11","author":"Nerg\u00e5rd","year":"2015","journal-title":"Surg. Obes. Relat. Dis."},{"key":"10.1016\/j.mce.2018.04.002_bib29","doi-asserted-by":"crossref","first-page":"548","DOI":"10.2337\/db09-0035","article-title":"The expression and function of glucose-dependent insulinotropic polypeptide in the embryonic mouse pancreas","volume":"60","author":"Prasadan","year":"2011","journal-title":"Diabetes"},{"key":"10.1016\/j.mce.2018.04.002_bib30","doi-asserted-by":"crossref","first-page":"1520","DOI":"10.1210\/jc.2014-3640","article-title":"Comparison of the utility of Cocaine- and Amphetamine-Regulated Transcript (CART), chromogranin A, and chromogranin B in neuroendocrine tumor diagnosis and assessment of disease progression","volume":"100","author":"Ramachandran","year":"2015","journal-title":"J. Clin. Endocrinol. Metabol."},{"key":"10.1016\/j.mce.2018.04.002_bib31","doi-asserted-by":"crossref","first-page":"1640","DOI":"10.2337\/diacare.24.9.1640","article-title":"T. Northern Sweden Monitoring of, D. Determinants in Cardiovascular, Impaired incretin response after a mixed meal is associated with insulin resistance in nondiabetic men","volume":"24","author":"Rask","year":"2001","journal-title":"Diabetes Care"},{"key":"10.1016\/j.mce.2018.04.002_bib32","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1016\/j.cmet.2008.11.002","article-title":"Glucose sensing in L cells: a primary cell study","volume":"8","author":"Reimann","year":"2008","journal-title":"Cell Metabol."},{"key":"10.1016\/j.mce.2018.04.002_bib33","first-page":"1349","article-title":"Development of neuroendocrine tumors in the gastrointestinal tract of transgenic mice. Heterogeneity of hormone expression","volume":"136","author":"Rindi","year":"1990","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.mce.2018.04.002_bib34","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1038\/nrn2493","article-title":"CART peptides: regulators of body weight, reward and other functions","volume":"9","author":"Rogge","year":"2008","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.mce.2018.04.002_bib35","doi-asserted-by":"crossref","first-page":"3208","DOI":"10.1074\/jbc.M112.437145","article-title":"Cocaine- and amphetamine-regulated transcript (CART) protects beta cells against glucotoxicity and increases cell proliferation","volume":"288","author":"Sathanoori","year":"2013","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.mce.2018.04.002_bib36","doi-asserted-by":"crossref","first-page":"789","DOI":"10.2337\/db12-0365","article-title":"The Wnt signaling pathway effector TCF7L2 controls gut and brain proglucagon gene expression and glucose homeostasis","volume":"62","author":"Shao","year":"2013","journal-title":"Diabetes"},{"key":"10.1016\/j.mce.2018.04.002_bib37","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/j.mce.2017.02.027","article-title":"Endogenous beta-cell CART regulates insulin secretion and transcription of beta-cell genes","volume":"447","author":"Shcherbina","year":"2017","journal-title":"Mol. Cell. Endocrinol."},{"key":"10.1016\/j.mce.2018.04.002_bib38","doi-asserted-by":"crossref","first-page":"G979","DOI":"10.1152\/ajpgi.00390.2013","article-title":"Impaired enteroendocrine development in intestinal-specific Islet1 mouse mutants causes impaired glucose homeostasis","volume":"307","author":"Terry","year":"2014","journal-title":"Am. J. Physiol. Gastrointest. Liver Physiol."},{"key":"10.1016\/j.mce.2018.04.002_bib39","doi-asserted-by":"crossref","first-page":"E550","DOI":"10.1152\/ajpendo.00326.2004","article-title":"Human duodenal enteroendocrine cells: source of both incretin peptides, GLP-1 and GIP","volume":"290","author":"Theodorakis","year":"2006","journal-title":"Am. J. Physiol. Endocrinol. Metab."},{"key":"10.1016\/j.mce.2018.04.002_bib40","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/S0014-5793(98)00543-2","article-title":"Purification and characterisation of a new hypothalamic satiety peptide, cocaine and amphetamine regulated transcript (CART), produced in yeast","volume":"428","author":"Thim","year":"1998","journal-title":"FEBS Lett."},{"key":"10.1016\/j.mce.2018.04.002_bib41","doi-asserted-by":"crossref","first-page":"2722","DOI":"10.1073\/pnas.96.6.2722","article-title":"Tissue-specific processing of cocaine- and amphetamine-regulated transcript peptides in the rat","volume":"96","author":"Thim","year":"1999","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.mce.2018.04.002_bib42","doi-asserted-by":"crossref","first-page":"4119","DOI":"10.1210\/en.2003-1648","article-title":"Cocaine- and amphetamine-regulated transcript peptide levels in blood exhibit a diurnal rhythm: regulation by glucocorticoids","volume":"145","author":"Vicentic","year":"2004","journal-title":"Endocrinology"},{"key":"10.1016\/j.mce.2018.04.002_bib43","doi-asserted-by":"crossref","first-page":"1934","DOI":"10.1016\/j.peptides.2006.03.031","article-title":"The CART receptors: background and recent advances","volume":"27","author":"Vicentic","year":"2006","journal-title":"Peptides"},{"key":"10.1016\/j.mce.2018.04.002_bib44","doi-asserted-by":"crossref","first-page":"2706","DOI":"10.1210\/jc.2002-021873","article-title":"Incretin secretion in relation to meal size and body weight in healthy subjects and people with type 1 and type 2 diabetes mellitus","volume":"88","author":"Vilsboll","year":"2003","journal-title":"J. Clin. Endocrinol. Metabol."},{"key":"10.1016\/j.mce.2018.04.002_bib45","doi-asserted-by":"crossref","first-page":"E988","DOI":"10.1152\/ajpendo.00398.2002","article-title":"Studies with GIP\/Ins cells indicate secretion by gut K cells is KATP channel independent","volume":"284","author":"Wang","year":"2003","journal-title":"Am. J. Physiol. Endocrinol. Metab."},{"key":"10.1016\/j.mce.2018.04.002_bib46","doi-asserted-by":"crossref","first-page":"2031","DOI":"10.1016\/j.peptides.2006.02.011","article-title":"CART is a novel islet regulatory peptide","volume":"27","author":"Wierup","year":"2006","journal-title":"Peptides"},{"key":"10.1016\/j.mce.2018.04.002_bib47","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1177\/002215540405200204","article-title":"Cocaine- and amphetamine-regulated transcript (CART) is expressed in several islet cell types during rat development","volume":"52","author":"Wierup","year":"2004","journal-title":"J. Histochem. Cytochem."},{"key":"10.1016\/j.mce.2018.04.002_bib48","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1177\/002215540405200301","article-title":"Ghrelin is expressed in a novel endocrine cell type in developing rat islets and inhibits insulin secretion from INS-1 (832\/13) cells","volume":"52","author":"Wierup","year":"2004","journal-title":"J. Histochem. Cytochem."},{"key":"10.1016\/j.mce.2018.04.002_bib49","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/j.regpep.2005.02.016","article-title":"CART knock out mice have impaired insulin secretion and glucose intolerance, altered beta cell morphology and increased body weight","volume":"129","author":"Wierup","year":"2005","journal-title":"Regul. Pept."},{"key":"10.1016\/j.mce.2018.04.002_bib50","doi-asserted-by":"crossref","first-page":"305","DOI":"10.2337\/diabetes.55.02.06.db04-1383","article-title":"CART regulates islet hormone secretion and is expressed in the beta-cells of type 2 diabetic rats","volume":"55","author":"Wierup","year":"2006","journal-title":"Diabetes"},{"key":"10.1016\/j.mce.2018.04.002_bib51","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1186\/1471-2202-8-51","article-title":"Characterisation of CART-containing neurons and cells in the porcine pancreas, gastro-intestinal tract, adrenal and thyroid glands","volume":"8","author":"Wierup","year":"2007","journal-title":"BMC Neurosci."},{"key":"10.1016\/j.mce.2018.04.002_bib52","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/j.psychres.2014.08.017","article-title":"Blood serum levels of CART peptide in patients with schizophrenia on clozapine monotherapy","volume":"220","author":"Wysokinski","year":"2014","journal-title":"Psychiatr. Res."},{"key":"10.1016\/j.mce.2018.04.002_bib53","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.bbrc.2016.11.012","article-title":"Glucose enhances rat islet function via stimulating CART expression","volume":"481","author":"Xu","year":"2016","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.mce.2018.04.002_bib54","doi-asserted-by":"crossref","first-page":"7474","DOI":"10.1523\/JNEUROSCI.21-19-07474.2001","article-title":"Cocaine- and amphetamine-regulated transcript peptide modulation of voltage-gated Ca2+ signaling in hippocampal neurons","volume":"21","author":"Yermolaieva","year":"2001","journal-title":"J. Neurosci. : Offic. J. Soc. Neurosci."},{"key":"10.1016\/j.mce.2018.04.002_bib55","doi-asserted-by":"crossref","first-page":"1457","DOI":"10.1074\/jbc.M411487200","article-title":"TCF-4 mediates cell type-specific regulation of proglucagon gene expression by beta-catenin and glycogen synthase kinase-3beta","volume":"280","author":"Yi","year":"2005","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.mce.2018.04.002_bib56","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1055\/s-0034-1383576","article-title":"Lower cocaine- and amphetamine-regulated transcript levels pose a risk for developing PCOS","volume":"46","author":"Yilmaz","year":"2014","journal-title":"Horm. Metab. Res."},{"issue":"24","key":"10.1016\/j.mce.2018.04.002_bib57","doi-asserted-by":"crossref","first-page":"6419","DOI":"10.1093\/hmg\/ddu359","article-title":"TCF7L2 is a master regulator of insulin production and processing","volume":"23","author":"Zhou","year":"2014","journal-title":"Hum. Mol. Genet."}],"container-title":["Molecular and Cellular Endocrinology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0303720718301217?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0303720718301217?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T14:04:50Z","timestamp":1759586690000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0303720718301217"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,11]]},"references-count":57,"alternative-id":["S0303720718301217"],"URL":"https:\/\/doi.org\/10.1016\/j.mce.2018.04.002","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.733013416.793544698","asserted-by":"object"}]},"ISSN":["0303-7207"],"issn-type":[{"value":"0303-7207","type":"print"}],"subject":[],"published":{"date-parts":[[2018,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Intestinal CART is a regulator of GIP and GLP-1 secretion and expression","name":"articletitle","label":"Article Title"},{"value":"Molecular and Cellular Endocrinology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.mce.2018.04.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}