{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T17:20:36Z","timestamp":1785864036821,"version":"3.56.0"},"reference-count":44,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100016112","name":"Xi'an Science and Technology Association","doi-asserted-by":"publisher","award":["095920201312"],"award-info":[{"award-number":["095920201312"]}],"id":[{"id":"10.13039\/501100016112","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100017596","name":"Natural Science Basic Research Program of Shaanxi Province","doi-asserted-by":"publisher","award":["2021JQ-071"],"award-info":[{"award-number":["2021JQ-071"]}],"id":[{"id":"10.13039\/501100017596","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81600679"],"award-info":[{"award-number":["81600679"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81800017"],"award-info":[{"award-number":["81800017"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Molecular and Cellular Endocrinology"],"published-print":{"date-parts":[[2022,4]]},"DOI":"10.1016\/j.mce.2022.111562","type":"journal-article","created":{"date-parts":[[2022,1,17]],"date-time":"2022-01-17T11:06:32Z","timestamp":1642417592000},"page":"111562","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"special_numbering":"C","title":["Pdcd4 promotes lipid deposition by attenuating PPAR\u03b1-mediated fatty acid oxidation in hepatocytes"],"prefix":"10.1016","volume":"545","author":[{"given":"Xiaojuan","family":"Du","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ezra Kombo","family":"Osoro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qian","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaofei","family":"Yan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dan","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Litao","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiajun","family":"Ren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lina","family":"Feng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nan","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaikai","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8144-919X","authenticated-orcid":false,"given":"Xudong","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo","family":"Zhong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fujun","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dongmin","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7114-6494","authenticated-orcid":false,"given":"Xi","family":"Lan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shemin","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.mce.2022.111562_bib1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/j.2040-4603.2018.tb00008.x","article-title":"Triglyceride metabolism in the liver","volume":"8","author":"Alves-Bezerra","year":"2017","journal-title":"Compr. Physiol."},{"issue":"4","key":"10.1016\/j.mce.2022.111562_bib2","doi-asserted-by":"crossref","first-page":"904","DOI":"10.1016\/j.bpj.2017.12.042","article-title":"The chemical potential of plasma membrane cholesterol: implications for cell biology","volume":"114","author":"Ayuyan","year":"2018","journal-title":"Biophys. J."},{"issue":"5","key":"10.1016\/j.mce.2022.111562_bib3","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1210\/er.2018-00064","article-title":"Molecular actions of PPAR\u03b1 in lipid metabolism and inflammation","volume":"39","author":"Bougarne","year":"2018","journal-title":"Endocr. Rev."},{"issue":"11","key":"10.1016\/j.mce.2022.111562_bib4","doi-asserted-by":"crossref","first-page":"2140","DOI":"10.1194\/jlr.M088419","article-title":"Extrahepatic PPAR\u03b1 modulates fatty acid oxidation and attenuates fasting-induced hepatosteatosis in mice","volume":"59","author":"Brocker","year":"2018","journal-title":"J. Lipid Res."},{"issue":"3","key":"10.1016\/j.mce.2022.111562_bib5","doi-asserted-by":"crossref","first-page":"810","DOI":"10.1002\/hep.24127","article-title":"Nonalcoholic fatty liver disease (NAFLD) activity score and the histopathologic diagnosis in NAFLD: distinct clinicopathologic meanings","volume":"53","author":"Brunt","year":"2011","journal-title":"Hepatology"},{"issue":"5","key":"10.1016\/j.mce.2022.111562_bib6","doi-asserted-by":"crossref","first-page":"1330","DOI":"10.1016\/j.fertnstert.2016.01.020","article-title":"Higher PDCD4 expression is associated with obesity, insulin resistance, lipid metabolism disorders, and granulosa cell apoptosis in polycystic ovary syndrome","volume":"105","author":"Ding","year":"2016","journal-title":"Fertil. Steril."},{"issue":"1","key":"10.1016\/j.mce.2022.111562_bib7","doi-asserted-by":"crossref","first-page":"e107","DOI":"10.11607\/jomi.te49","article-title":"Sp1-dependent regulation of PPAR\u03b1 in bone metabolism","volume":"29","author":"Duttenhoefer","year":"2014","journal-title":"Int. J. Oral Maxillofac. Implants"},{"issue":"8","key":"10.1016\/j.mce.2022.111562_bib8","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1016\/j.metabol.2016.01.012","article-title":"Epidemiology and natural history of non-alcoholic fatty liver disease","volume":"65","author":"Fazel","year":"2016","journal-title":"Metab. Clin. Exp."},{"key":"10.1016\/j.mce.2022.111562_bib9","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/0076-6879(83)98152-1","article-title":"Receptor-mediated endocytosis of low-density lipoprotein in cultured cells","volume":"98","author":"Goldstein","year":"1983","journal-title":"Methods Enzymol."},{"issue":"7","key":"10.1016\/j.mce.2022.111562_bib10","doi-asserted-by":"crossref","first-page":"1469","DOI":"10.1093\/carcin\/bgu008","article-title":"Tumor suppressor PDCD4 inhibits NF-\u03baB-dependent transcription in human glioblastoma cells by direct interaction with p65","volume":"35","author":"Hwang","year":"2014","journal-title":"Carcinogenesis"},{"issue":"18","key":"10.1016\/j.mce.2022.111562_bib11","doi-asserted-by":"crossref","first-page":"3313","DOI":"10.1007\/s00018-018-2860-6","article-title":"Molecular mechanisms of hepatic lipid accumulation in non-alcoholic fatty liver disease","volume":"75","author":"Ipsen","year":"2018","journal-title":"Cell. Mol. Life Sci. : CMLS"},{"issue":"6","key":"10.1016\/j.mce.2022.111562_bib12","doi-asserted-by":"crossref","first-page":"1313","DOI":"10.1002\/hep.20701","article-title":"Design and validation of a histological scoring system for nonalcoholic fatty liver disease","volume":"41","author":"Kleiner","year":"2005","journal-title":"Hepatology"},{"issue":"2","key":"10.1016\/j.mce.2022.111562_bib13","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1177\/1535370214554531","article-title":"Identification of differentially expressed genes related to metabolic syndrome induced with high-fat diet in E3 rats","volume":"240","author":"Lan","year":"2015","journal-title":"Exp. Biol. Med."},{"issue":"1","key":"10.1016\/j.mce.2022.111562_bib14","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1002\/hep.28391","article-title":"A novel long noncoding RNA Lnc-HC binds hnRNPA2B1 to regulate expressions of Cyp7a1 and Abca1 in hepatocytic cholesterol metabolism","volume":"64","author":"Lan","year":"2016","journal-title":"Hepatology"},{"key":"10.1016\/j.mce.2022.111562_bib15","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1016\/j.omtn.2019.10.018","article-title":"Long noncoding RNA lnc-HC regulates PPAR\u03b3-mediated hepatic lipid metabolism through miR-130b-3p","volume":"18","author":"Lan","year":"2019","journal-title":"Mol. Ther. Nucleic Acids"},{"issue":"31","key":"10.1016\/j.mce.2022.111562_bib16","doi-asserted-by":"crossref","first-page":"4550","DOI":"10.1038\/sj.onc.1210234","article-title":"Tumor suppressor Pdcd4 inhibits invasion\/intravasation and regulates urokinase receptor (u-PAR) gene expression via Sp-transcription factors","volume":"26","author":"Leupold","year":"2007","journal-title":"Oncogene"},{"issue":"1\u20132","key":"10.1016\/j.mce.2022.111562_bib17","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.mce.2011.06.028","article-title":"High expression of liver histone deacetylase 3 contributes to high-fat-diet-induced metabolic syndrome by suppressing the PPAR-\u03b3 and LXR-\u03b1-pathways in E3 rats","volume":"344","author":"Li","year":"2011","journal-title":"Mol. Cell. Endocrinol."},{"issue":"3","key":"10.1016\/j.mce.2022.111562_bib18","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1016\/j.jhep.2014.10.039","article-title":"Molecular mechanism of PPAR\u03b1 action and its impact on lipid metabolism, inflammation and fibrosis in non-alcoholic fatty liver disease","volume":"62","author":"Pawlak","year":"2015","journal-title":"J. Hepatol."},{"issue":"1","key":"10.1016\/j.mce.2022.111562_bib19","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1097\/TP.0000000000002480","article-title":"Nonalcoholic fatty liver disease: basic pathogenetic mechanisms in the progression from NAFLD to NASH","volume":"103","author":"Pierantonelli","year":"2019","journal-title":"Transplantation"},{"issue":"4","key":"10.1016\/j.mce.2022.111562_bib20","doi-asserted-by":"crossref","first-page":"1193","DOI":"10.1172\/JCI88893","article-title":"Nutrient-sensing nuclear receptors PPAR\u03b1 and FXR control liver energy balance","volume":"127","author":"Preidis","year":"2017","journal-title":"J. Clin. Invest."},{"issue":"4","key":"10.1016\/j.mce.2022.111562_bib21","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1002\/hep.21763","article-title":"A lipidomic analysis of nonalcoholic fatty liver disease","volume":"46","author":"Puri","year":"2007","journal-title":"Hepatology"},{"issue":"27","key":"10.1016\/j.mce.2022.111562_bib22","doi-asserted-by":"crossref","first-page":"3296","DOI":"10.1038\/onc.2013.150","article-title":"HBx-mediated miR-21 upregulation represses tumor-suppressor function of PDCD4 in hepatocellular carcinoma","volume":"32","author":"Qiu","year":"2013","journal-title":"Oncogene"},{"key":"10.1016\/j.mce.2022.111562_bib23","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1186\/1476-4598-9-238","article-title":"Programmed cell death 4 loss increases tumor cell invasion and is regulated by miR-21 in oral squamous cell carcinoma","volume":"9","author":"Reis","year":"2010","journal-title":"Mol. Cancer"},{"issue":"29","key":"10.1016\/j.mce.2022.111562_bib24","doi-asserted-by":"crossref","first-page":"12030","DOI":"10.1073\/pnas.1101450108","article-title":"The microRNA-21-PDCD4 axis prevents type 1 diabetes by blocking pancreatic beta cell death","volume":"108","author":"Ruan","year":"2011","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"issue":"2","key":"10.1016\/j.mce.2022.111562_bib25","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/0378-1119(95)00607-9","article-title":"Isolation of a novel mouse gene MA-3 that is induced upon programmed cell death","volume":"166","author":"Shibahara","year":"1995","journal-title":"Gene"},{"issue":"7","key":"10.1016\/j.mce.2022.111562_bib26","doi-asserted-by":"crossref","first-page":"3148","DOI":"10.1158\/0008-5472.CAN-08-2334","article-title":"Programmed cell death protein 4 down-regulates Y-box binding protein-1 expression via a direct interaction with Twist1 to suppress cancer cell growth","volume":"69","author":"Shiota","year":"2009","journal-title":"Cancer Res."},{"issue":"42","key":"10.1016\/j.mce.2022.111562_bib27","doi-asserted-by":"crossref","first-page":"3758","DOI":"10.1038\/onc.2009.239","article-title":"Disruption of the Pdcd4 tumor suppressor gene in chicken DT40 cells reveals its role in the DNA-damage response","volume":"28","author":"Singh","year":"2009","journal-title":"Oncogene"},{"issue":"7242","key":"10.1016\/j.mce.2022.111562_bib28","doi-asserted-by":"crossref","first-page":"1131","DOI":"10.1038\/nature07976","article-title":"Autophagy regulates lipid metabolism","volume":"458","author":"Singh","year":"2009","journal-title":"Nature"},{"issue":"49","key":"10.1016\/j.mce.2022.111562_bib29","doi-asserted-by":"crossref","first-page":"4864","DOI":"10.1038\/onc.2011.202","article-title":"Pdcd4 directly binds the coding region of c-myb mRNA and suppresses its translation","volume":"30","author":"Singh","year":"2011","journal-title":"Oncogene"},{"issue":"8","key":"10.1016\/j.mce.2022.111562_bib30","doi-asserted-by":"crossref","first-page":"1455","DOI":"10.1080\/15548627.2019.1609847","article-title":"Lysosomal inhibition attenuates peroxisomal gene transcription via suppression of PPARA and PPARGC1A levels","volume":"15","author":"Tan","year":"2019","journal-title":"Autophagy"},{"issue":"11","key":"10.1016\/j.mce.2022.111562_bib31","doi-asserted-by":"crossref","first-page":"1527","DOI":"10.1038\/sj.onc.1210793","article-title":"Downregulation of tumor suppressor Pdcd4 promotes invasion and activates both beta-catenin\/Tcf and AP-1-dependent transcription in colon carcinoma cells","volume":"27","author":"Wang","year":"2008","journal-title":"Oncogene"},{"issue":"3","key":"10.1016\/j.mce.2022.111562_bib32","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1038\/labinvest.2012.174","article-title":"The inhibitory action of PDCD4 in lipopolysaccharide\/D-galactosamine-induced acute liver injury","volume":"93","author":"Wang","year":"2013","journal-title":"Lab. Invest. J. Techn. Method Pathol."},{"issue":"12","key":"10.1016\/j.mce.2022.111562_bib33","doi-asserted-by":"crossref","first-page":"4132","DOI":"10.2337\/db13-0097","article-title":"Programmed cell death-4 deficiency prevents diet-induced obesity, adipose tissue inflammation, and insulin resistance","volume":"62","author":"Wang","year":"2013","journal-title":"Diabetes"},{"issue":"1","key":"10.1016\/j.mce.2022.111562_bib34","doi-asserted-by":"crossref","DOI":"10.1038\/cddis.2015.416","article-title":"Pdcd4 deficiency enhances macrophage lipoautophagy and attenuates foam cell formation and atherosclerosis in mice","volume":"7","author":"Wang","year":"2016","journal-title":"Cell Death Dis."},{"issue":"45","key":"10.1016\/j.mce.2022.111562_bib35","doi-asserted-by":"crossref","first-page":"6225","DOI":"10.1038\/onc.2017.228","article-title":"Tumor suppressor Pdcd4 attenuates Sin1 translation to inhibit invasion in colon carcinoma","volume":"36","author":"Wang","year":"2017","journal-title":"Oncogene"},{"issue":"50","key":"10.1016\/j.mce.2022.111562_bib36","doi-asserted-by":"crossref","first-page":"42855","DOI":"10.1074\/jbc.M111.269456","article-title":"Tumor suppressor protein Pdcd4 inhibits translation of p53 mRNA","volume":"286","author":"Wedeken","year":"2011","journal-title":"J. Biol. Chem."},{"issue":"24","key":"10.1016\/j.mce.2022.111562_bib37","doi-asserted-by":"crossref","first-page":"15925","DOI":"10.1021\/acs.est.0c01073","article-title":"A novel mechanism of monoethylhexyl phthalate in lipid accumulation via inhibiting fatty acid beta-oxidation on hepatic cells","volume":"54","author":"Xu","year":"2020","journal-title":"Environ. Sci. Technol."},{"issue":"2","key":"10.1016\/j.mce.2022.111562_bib38","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1042\/BCJ20180517","article-title":"ZNF300 stimulates fatty acid oxidation and alleviates hepatosteatosis through regulating PPAR\u03b1","volume":"476","author":"Yan","year":"2019","journal-title":"Biochem. J."},{"issue":"1","key":"10.1016\/j.mce.2022.111562_bib39","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1128\/MCB.23.1.26-37.2003","article-title":"The transformation suppressor Pdcd4 is a novel eukaryotic translation initiation factor 4A binding protein that inhibits translation","volume":"23","author":"Yang","year":"2003","journal-title":"Mol. Cell Biol."},{"issue":"9","key":"10.1016\/j.mce.2022.111562_bib40","doi-asserted-by":"crossref","first-page":"3894","DOI":"10.1128\/MCB.24.9.3894-3906.2004","article-title":"A novel function of the MA-3 domains in transformation and translation suppressor Pdcd4 is essential for its binding to eukaryotic translation initiation factor 4A","volume":"24","author":"Yang","year":"2004","journal-title":"Mol. Cell Biol."},{"issue":"1","key":"10.1016\/j.mce.2022.111562_bib41","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1038\/nrgastro.2017.109","article-title":"Global burden of NAFLD and NASH: trends, predictions, risk factors and prevention","volume":"15","author":"Younossi","year":"2018","journal-title":"Nat. Rev. Gastroenterol. Hepatol."},{"issue":"6","key":"10.1016\/j.mce.2022.111562_bib42","doi-asserted-by":"crossref","first-page":"2672","DOI":"10.1002\/hep.30251","article-title":"Global perspectives on nonalcoholic fatty liver disease and nonalcoholic steatohepatitis","volume":"69","author":"Younossi","year":"2019","journal-title":"Hepatology"},{"issue":"1","key":"10.1016\/j.mce.2022.111562_bib43","doi-asserted-by":"crossref","DOI":"10.1136\/bmjdrc-2019-001081","article-title":"PDCD4 deficiency ameliorates left ventricular remodeling and insulin resistance in a rat model of type 2 diabetic cardiomyopathy","volume":"8","author":"Zhang","year":"2020","journal-title":"BMJ Open Diabetes Res. care"},{"issue":"6","key":"10.1016\/j.mce.2022.111562_bib44","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1189\/jlb.3A0313-136RRR","article-title":"Pdcd4 modulates markers of macrophage alternative activation and airway remodeling in antigen-induced pulmonary inflammation","volume":"96","author":"Zhong","year":"2014","journal-title":"J. Leukoc. Biol."}],"container-title":["Molecular and Cellular Endocrinology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0303720722000090?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0303720722000090?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T14:20:29Z","timestamp":1759587629000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0303720722000090"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4]]},"references-count":44,"alternative-id":["S0303720722000090"],"URL":"https:\/\/doi.org\/10.1016\/j.mce.2022.111562","relation":{},"ISSN":["0303-7207"],"issn-type":[{"value":"0303-7207","type":"print"}],"subject":[],"published":{"date-parts":[[2022,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Pdcd4 promotes lipid deposition by attenuating PPAR\u03b1-mediated fatty acid oxidation in hepatocytes","name":"articletitle","label":"Article Title"},{"value":"Molecular and Cellular Endocrinology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.mce.2022.111562","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"111562"}}