{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T05:01:11Z","timestamp":1789707671797,"version":"4.0.1"},"reference-count":47,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100004263","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado do Rio Grande do Sul","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004263","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004909","name":"Universidade Federal do Rio Grande do Sul","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004909","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Molecular and Cellular Endocrinology"],"published-print":{"date-parts":[[2024,9]]},"DOI":"10.1016\/j.mce.2024.112279","type":"journal-article","created":{"date-parts":[[2024,5,24]],"date-time":"2024-05-24T06:27:42Z","timestamp":1716532062000},"page":"112279","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"special_numbering":"C","title":["Melatonin improves nitric oxide bioavailability in isoproterenol induced myocardial injury"],"prefix":"10.1016","volume":"591","author":[{"given":"Ramison","family":"Santos","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick","family":"Turck","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8853-0270","authenticated-orcid":false,"given":"Victor","family":"de Mello Palma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4033-8431","authenticated-orcid":false,"given":"Fernanda","family":"Visioli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vanessa Duarte","family":"Ortiz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabel Cristina Teixeira","family":"Proen\u00e7a","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T\u00e2nia Regina G.","family":"Fernandes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elissa","family":"Fernandes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvio","family":"Tasca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristina Campos","family":"Carraro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adriane","family":"Bell\u00f3-Klein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alex Sander","family":"da Rosa Araujo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neelam","family":"Khaper","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandre Luz","family":"de Castro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.mce.2024.112279_bib1","first-page":"3217","article-title":"Simvastatin prevents isoproterenol-induced cardiac hypertrophy through modulation of the JAK\/STAT pathway","volume":"9","author":"Al-Rasheed","year":"2015","journal-title":"Drug Des. Dev. Ther."},{"key":"10.1016\/j.mce.2024.112279_bib2","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2022.112900","article-title":"Umbelliferone prevents isoproterenol-induced myocardial injury by upregulating Nrf2\/HO-1 signaling, and attenuating oxidative stress, inflammation, and cell death in rats","volume":"149","author":"Althunibat","year":"2022","journal-title":"Biomed. Pharmacother."},{"issue":"18","key":"10.1016\/j.mce.2024.112279_bib3","doi-asserted-by":"crossref","first-page":"4342","DOI":"10.3390\/ijms20184342","article-title":"Cardioprotective melatonin: translating from proof-of-concept studies to therapeutic use","volume":"20","author":"Baltatu","year":"2019","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.mce.2024.112279_bib4","doi-asserted-by":"crossref","first-page":"3955","DOI":"10.1007\/s00018-017-2613-y","article-title":"Melatonin, mitochondria and hypertension","volume":"74","author":"Baltatu","year":"2017","journal-title":"Cell. Mol. Life Sci."},{"issue":"62","key":"10.1016\/j.mce.2024.112279_bib5","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.niox.2016.12.001","article-title":"Melatonin influences NO\/NOS pathway and reduces oxidative and nitrosative stress in a model of hypoxic-ischemic brain damage","volume":"30","author":"Blanco","year":"2017","journal-title":"Nitric Oxide"},{"issue":"52","key":"10.1016\/j.mce.2024.112279_bib6","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1016\/S0076-6879(78)52032-6","article-title":"Microsomal lipid peroxidation","volume":"978","author":"Buege","year":"1978","journal-title":"Methods Enzymol."},{"issue":"2","key":"10.1016\/j.mce.2024.112279_bib7","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1385\/ENDO:27:2:189","article-title":"A review of the multiple actions of melatonin on the immune system","volume":"27","author":"Carrillo-Vico","year":"2005","journal-title":"Endocrine"},{"key":"10.1016\/j.mce.2024.112279_bib8","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1161\/CIRCRESAHA.111.243196","article-title":"The fire within: cardiac inflammatory signaling in health and disease","volume":"110","author":"Coggins","year":"2012","journal-title":"Circ. Res."},{"issue":"2","key":"10.1016\/j.mce.2024.112279_bib9","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1007\/s10495-015-1204-3","article-title":"Thyroid hormones improve cardiac function and decrease expression of pro-apoptotic proteins in the heart of rats 14 days after infarction","volume":"21","author":"De Castro","year":"2016","journal-title":"Apoptosis"},{"key":"10.1016\/j.mce.2024.112279_bib10","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.mce.2017.09.003","article-title":"Thyroid hormones decrease the proinflammatory TLR4\/NF-\u03ba\u03b2 pathway and improve functional parameters of the left ventricle of infarcted rats","volume":"461","author":"De Castro","year":"2018","journal-title":"Mol. Cell. Endocrinol."},{"key":"10.1016\/j.mce.2024.112279_bib11","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.mce.2014.04.010","article-title":"Cardioprotective effects of thyroid hormones in a rat model of myocardial infarction are associated with oxidative stress reduction","volume":"391","author":"De Castro","year":"2014","journal-title":"Mol. Cell. Endocrinol."},{"key":"10.1016\/j.mce.2024.112279_bib12","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1007\/s11010-015-2501-4","article-title":"T3 and T4 decrease ROS levels and increase endothelial nitric oxide synthase expression in the myocardium of infarcted rats","volume":"408","author":"De Castro","year":"2015","journal-title":"Mol. Cell. Biochem."},{"key":"10.1016\/j.mce.2024.112279_bib13","doi-asserted-by":"crossref","DOI":"10.1016\/j.cbi.2022.110090","article-title":"Thymoquinone regulates nitric oxide synthase enzymes and receptor-interacting serine-threonine kinases in isoproterenol-induced myocardial infarcted rats","volume":"365","author":"Deger","year":"2022","journal-title":"Chem. Biol. Interact."},{"issue":"2","key":"10.1016\/j.mce.2024.112279_bib14","article-title":"Ghrelin ameliorated inflammation and oxidative stress in isoproterenol induced myocardial infarction through the endothelial nitric oxide synthase (eNOS)\/nuclear factor erythroid 2-related factor-2 (NRF2)\/heme oxygenase-1 (HO-1) signaling pathway","volume":"72","author":"El-Shaer","year":"2021","journal-title":"J. Physiol. Pharmacol."},{"key":"10.1016\/j.mce.2024.112279_bib15","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1016\/j.ijcard.2021.09.001","article-title":"Nitric oxide as a fragile switch between cardioprotection and cardiac injury","volume":"343","author":"Fender","year":"2021","journal-title":"Int. J. Cardiol."},{"key":"10.1016\/j.mce.2024.112279_bib16","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/S0076-6879(99)01068-X","article-title":"Measuring nitric oxide production in human clinical studies","volume":"301","author":"Granger","year":"1999","journal-title":"Methods Enzymol."},{"issue":"4","key":"10.1016\/j.mce.2024.112279_bib17","first-page":"469","article-title":"Nitric oxide and superoxide in inflammation and immune regulation","volume":"54","author":"Guzik","year":"2003","journal-title":"J. Physiol. Pharmacol."},{"key":"10.1016\/j.mce.2024.112279_bib18","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1016\/j.omtn.2019.12.002","article-title":"MEL ameliorates post-SAH cerebral vasospasm by affecting the expression of eNOS and HIF1\u03b1 via H19\/miR-138\/eNOS\/NO and H19\/miR-675\/HIF1\u03b1","volume":"19","author":"Hou","year":"2020","journal-title":"Mol. Ther. Nucleic Acids"},{"key":"10.1016\/j.mce.2024.112279_bib19","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1016\/j.hlc.2014.11.018","article-title":"Cardioprotective efect of hydrogen-rich saline on isoproterenol-induced myocardial infarction in rats","volume":"24","author":"Jing","year":"2015","journal-title":"Heart Lung Circ."},{"issue":"10","key":"10.1016\/j.mce.2024.112279_bib20","doi-asserted-by":"crossref","first-page":"1809","DOI":"10.1007\/s00210-020-01860-y","article-title":"Role of nitric oxide in mediating the cardioprotective effect of agomelatine against isoproterenol-induced myocardial injury in rats","volume":"393","author":"Khalaf","year":"2020","journal-title":"Naunyn-Schmiedeberg\u2019s Arch. Pharmacol."},{"key":"10.1016\/j.mce.2024.112279_bib21","first-page":"59","article-title":"A method for quantification and correction of proteins after transfer to immobilization membranes","volume":"36","author":"Klein","year":"1995","journal-title":"Biochem. Mol. Biol. Int."},{"key":"10.1016\/j.mce.2024.112279_bib22","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1093\/eurjhf\/hfn026","article-title":"Isoproterenol induced heart failure in the rat is associated with nitric oxide dependent functional alterations of cardiac function","volume":"11","author":"K\u0159enek","year":"2009","journal-title":"Eur. J. Heart Fail."},{"issue":"7","key":"10.1016\/j.mce.2024.112279_bib23","doi-asserted-by":"crossref","first-page":"2742","DOI":"10.1096\/fj.12-224691","article-title":"Metabolism of melatonin and biological activity of intermediates of melatoninergic pathway in human skin cells","volume":"27","author":"Kim","year":"2013","journal-title":"Faseb. J."},{"key":"10.1016\/j.mce.2024.112279_bib24","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1038\/227680a0","article-title":"Cleavage of structural proteins during the assembly of the head of bacteriophage T4","volume":"227","author":"Laemmli","year":"1970","journal-title":"Nature"},{"key":"10.1016\/j.mce.2024.112279_bib25","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1021\/tx00026a012","article-title":"Evaluation ofthe probe 20 ,70-dichlorofluorescin as an indicator of reactive oxygen species formation and oxidative stress","volume":"5","author":"Lebel","year":"1992","journal-title":"Chem. Res. Toxicol."},{"issue":"1","key":"10.1016\/j.mce.2024.112279_bib27","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1186\/s13568-020-01065-9","article-title":"Cardioprotective effects of garcinol following myocardial infarction in rats with isoproterenol-induced heart failure","volume":"10","author":"Li","year":"2020","journal-title":"Amb. Express"},{"key":"10.1016\/j.mce.2024.112279_bib28","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1177\/030089168507100305","article-title":"Comparison of lipid peroxidation and myocardial damage induced by adramiycin and 4\u2032-epiadramiycin in mice","volume":"71","author":"Llesuy","year":"1985","journal-title":"Tumori"},{"key":"10.1016\/j.mce.2024.112279_bib29","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S0021-9258(19)52451-6","article-title":"Protein measurement with the Folin phenol reagent","volume":"193","author":"Lowry","year":"1951","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.mce.2024.112279_bib30","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1016\/j.bbrc.2004.07.048","article-title":"Activation of nuclear factor-kB and its proinflammatory mediator cascade in the infarcted rat heart","volume":"321","author":"Lu","year":"2004","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.mce.2024.112279_bib31","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2020.153405","article-title":"Nootkatone attenuates myocardial oxidative damage, inflammation, and apoptosis in isoproterenol-induced myocardial infarction in rats","volume":"84","author":"Meeran","year":"2021","journal-title":"Phytomedicine"},{"issue":"2","key":"10.1016\/j.mce.2024.112279_bib32","doi-asserted-by":"crossref","first-page":"141","DOI":"10.4149\/gpb_2012_015","article-title":"Morphological and functional characteristics of models of experimental myocardial injury induced by isoproterenol","volume":"31","author":"Nichtova","year":"2012","journal-title":"Gen. Physiol. Biophys."},{"key":"10.1016\/j.mce.2024.112279_bib33","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1590\/S0100-879X2006000500016","article-title":"Performance of two-dimensional Doppler echocardiography for the assessment of infarct size and left ventricular function in rats","volume":"39","author":"Nozawa","year":"2006","journal-title":"Braz. J. Med. Biol. Res."},{"key":"10.1016\/j.mce.2024.112279_bib34","doi-asserted-by":"crossref","first-page":"H530","DOI":"10.1152\/ajpheart.00549.2006","article-title":"Inhibition of NF-\u03ba\u03b2 improves left ventricular remodeling and cardiac dysfunction after myocardial infarction","volume":"292","author":"Onai","year":"2007","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"issue":"1\u20133","key":"10.1016\/j.mce.2024.112279_bib35","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/j.ejphar.2010.06.065","article-title":"Cardioprotective effect of melatonin against isoproterenol induced myocardial infarction in rats: a biochemical, electrocardiographic and histoarchitectural evaluation","volume":"644","author":"Patel","year":"2010","journal-title":"Eur. J. Pharmacol."},{"issue":"7","key":"10.1016\/j.mce.2024.112279_bib36","doi-asserted-by":"crossref","first-page":"6107","DOI":"10.3390\/ijms24076107","article-title":"Platelets and cardioprotection: the role of nitric oxide and carbon oxide","volume":"24","author":"Russo","year":"2023","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.mce.2024.112279_bib37","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1016\/0003-2697(68)90092-4","article-title":"Estimation of total, protein-bound, and nonprotein sulfhydryl groups in tissue with ellman's reagent","volume":"25","author":"Sedlak","year":"1968","journal-title":"Anal. Biochem."},{"issue":"2","key":"10.1016\/j.mce.2024.112279_bib38","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1111\/jpi.12154","article-title":"Melatonin reduces cardiac remodeling and improves survival in rats with isoproterenol-induced heart failure","volume":"57","author":"Simko","year":"2014","journal-title":"J. Pineal Res."},{"issue":"21","key":"10.1016\/j.mce.2024.112279_bib39","doi-asserted-by":"crossref","first-page":"3913","DOI":"10.1007\/s00018-017-2617-7","article-title":"Melatonin, mitochondria, and the skin","volume":"74","author":"Slominski","year":"2017","journal-title":"Cell. Mol. Life Sci."},{"issue":"3","key":"10.1016\/j.mce.2024.112279_bib40","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1016\/j.jid.2017.10.025","article-title":"Melatonin: a cutaneous perspective on its production, metabolism, and functions","volume":"138","author":"Slominski","year":"2018","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.mce.2024.112279_bib41","doi-asserted-by":"crossref","DOI":"10.3390\/ijms242015496","article-title":"Melatonin and its metabolites can serve as agonists on the aryl hydrocarbon receptor and peroxisome proliferator-activated receptor gamma","volume":"24","author":"Slominski","year":"2023","journal-title":"Int. J. Mol. Sci."},{"issue":"7","key":"10.1016\/j.mce.2024.112279_bib42","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1111\/exd.13208","article-title":"Metabolism of melatonin in the skin: why is it important?","volume":"26","author":"Slominski","year":"2017","journal-title":"Exp. Dermatol."},{"key":"10.1016\/j.mce.2024.112279_bib43","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1016\/j.lfs.2010.10.008","article-title":"Bone marrow derived cells decrease inflammation but not oxidative stress in an experimental model of acute myocardial infarction","volume":"87","author":"Tavares","year":"2010","journal-title":"Life Sci."},{"issue":"3","key":"10.1016\/j.mce.2024.112279_bib44","doi-asserted-by":"crossref","first-page":"434","DOI":"10.2174\/1570159X14666161228122115","article-title":"Melatonin: pharmacology, functions and therapeutic benefits","volume":"15","author":"Tordjman","year":"2017","journal-title":"Curr. Neuropharmacol."},{"key":"10.1016\/j.mce.2024.112279_bib45","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.1016\/j.biopha.2017.08.009","article-title":"Molecular understanding of the protective role of natural products on isoproterenol-induced myocardial infarction: a review","volume":"94","author":"Wong","year":"2017","journal-title":"Biomed. Pharmacother."},{"issue":"3","key":"10.1016\/j.mce.2024.112279_bib46","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1034\/j.1600-079X.2001.300303.x","article-title":"Melatonin prevents endotoxin-induced circulatory failure in rats","volume":"30","author":"Wu","year":"2001","journal-title":"J. Pineal Res."},{"key":"10.1016\/j.mce.2024.112279_bib47","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1111\/j.1745-7254.2007.00485.x","article-title":"Urotensin II accelerates cardiac fibrosis and hypertrophy of rats induced by isoproterenol","volume":"28","author":"Zhang","year":"2007","journal-title":"Acta Pharmacol. Sin."},{"issue":"1\u20132","key":"10.1016\/j.mce.2024.112279_bib48","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1007\/s11010-019-03652-2","article-title":"Role of inflammation, oxidative stress, and autonomic nervous system activation during the development of right and left cardiac remodeling in experimental pulmonary arterial hypertension","volume":"464","author":"Zimmer","year":"2020","journal-title":"Mol. Cell. Biochem."}],"container-title":["Molecular and Cellular Endocrinology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0303720724001357?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0303720724001357?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,6,13]],"date-time":"2024-06-13T01:28:24Z","timestamp":1718242104000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0303720724001357"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9]]},"references-count":47,"alternative-id":["S0303720724001357"],"URL":"https:\/\/doi.org\/10.1016\/j.mce.2024.112279","relation":{},"ISSN":["0303-7207"],"issn-type":[{"value":"0303-7207","type":"print"}],"subject":[],"published":{"date-parts":[[2024,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Melatonin improves nitric oxide bioavailability in isoproterenol induced myocardial injury","name":"articletitle","label":"Article Title"},{"value":"Molecular and Cellular Endocrinology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.mce.2024.112279","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"112279"}}