{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T18:28:58Z","timestamp":1790620138712,"version":"4.1.0"},"reference-count":59,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,6,25]],"date-time":"2025-06-25T00:00:00Z","timestamp":1750809600000},"content-version":"am","delay-in-days":267,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100000071","name":"National Institute of Child Health and Human Development","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000071","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009633","name":"NICHD","doi-asserted-by":"publisher","award":["HD065138"],"award-info":[{"award-number":["HD065138"]}],"id":[{"id":"10.13039\/100009633","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009633","name":"NICHD","doi-asserted-by":"publisher","award":["HD066248"],"award-info":[{"award-number":["HD066248"]}],"id":[{"id":"10.13039\/100009633","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009633","name":"NICHD","doi-asserted-by":"publisher","award":["HD079625"],"award-info":[{"award-number":["HD079625"]}],"id":[{"id":"10.13039\/100009633","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Molecular and Cellular Endocrinology"],"published-print":{"date-parts":[[2024,10]]},"DOI":"10.1016\/j.mce.2024.112290","type":"journal-article","created":{"date-parts":[[2024,5,31]],"date-time":"2024-05-31T11:30:24Z","timestamp":1717155024000},"page":"112290","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"special_numbering":"C","title":["Dual inhibition of AKT and ERK1\/2 pathways restores the expression of progesterone Receptor-B in endometriotic lesions through epigenetic mechanisms"],"prefix":"10.1016","volume":"592","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5272-288X","authenticated-orcid":false,"given":"Sudipta","family":"Dutta","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"JeHoon","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sakhila K.","family":"Banu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joe A.","family":"Arosh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.mce.2024.112290_bib1","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1159\/000235871","article-title":"Apoptosis in endometriosis","volume":"68","author":"Agic","year":"2009","journal-title":"Gynecol. Obstet. Invest."},{"issue":"4","key":"10.1016\/j.mce.2024.112290_bib2","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1210\/me.2006-0244","article-title":"Dynamic histone acetylation\/deacetylation with progesterone receptor-mediated transcription","volume":"21","author":"Aoyagi","year":"2007","journal-title":"Mol. Endocrinol."},{"key":"10.1016\/j.mce.2024.112290_bib3","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/j.mce.2018.12.011","article-title":"Dual inhibition of ERK1\/2 and AKT pathways is required to suppress the growth and survival of endometriotic cells and lesions","volume":"484","author":"Arosh","year":"2019","journal-title":"Mol. Cell. Endocrinol."},{"issue":"7","key":"10.1016\/j.mce.2024.112290_bib4","doi-asserted-by":"crossref","first-page":"3076","DOI":"10.1210\/en.2002-0088","article-title":"Molecular cloning and characterization of bovine prostaglandin E2 receptors EP2 and EP4: expression and regulation in endometrium and myometrium during the estrous cycle and early pregnancy","volume":"144","author":"Arosh","year":"2003","journal-title":"Endocrinology"},{"issue":"31","key":"10.1016\/j.mce.2024.112290_bib5","doi-asserted-by":"crossref","first-page":"9716","DOI":"10.1073\/pnas.1507931112","article-title":"Molecular and preclinical basis to inhibit PGE2 receptors EP2 and EP4 as a novel nonsteroidal therapy for endometriosis","volume":"112","author":"Arosh","year":"2015","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.mce.2024.112290_bib6","doi-asserted-by":"crossref","DOI":"10.1016\/j.mce.2021.111446","article-title":"Effects of dual inhibition of AKT and ERK1\/2 pathways on endometrial pro-inflammatory, hormonal, and epigenetic microenvironment in endometriosis","volume":"539","author":"Arosh","year":"2022","journal-title":"Mol. Cell. Endocrinol."},{"issue":"8","key":"10.1016\/j.mce.2024.112290_bib7","first-page":"2897","article-title":"Progesterone receptor isoform A but not B is expressed in endometriosis","volume":"85","author":"Attia","year":"2000","journal-title":"J. Clin. Endocrinol. Metab."},{"issue":"1","key":"10.1016\/j.mce.2024.112290_bib8","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1210\/en.2007-1087","article-title":"Molecular cloning and characterization of prostaglandin transporter in ovine endometrium: role of mitogen activated protein kinase pathways in release of prostaglandin F2 alpha","volume":"149","author":"Banu","year":"2008","journal-title":"Endocrinology"},{"issue":"8","key":"10.1016\/j.mce.2024.112290_bib9","doi-asserted-by":"crossref","first-page":"1291","DOI":"10.1210\/me.2009-0017","article-title":"Selective inhibition of prostaglandin E2 receptors EP2 and EP4 induces apoptosis of human endometriotic cells through suppression of ERK1\/2, AKT, NFkB and b-catenin pathways and activation of intrinsic apoptotic mechanisms","volume":"23","author":"Banu","year":"2009","journal-title":"Mol. Endocrinol."},{"issue":"9","key":"10.1016\/j.mce.2024.112290_bib10","doi-asserted-by":"crossref","first-page":"1153","DOI":"10.1177\/1933719115585145","article-title":"Abundance and localization of progesterone receptor isoforms in endometrium in women with and without endometriosis and in peritoneal and ovarian endometriotic implants","volume":"22","author":"Bedaiwy","year":"2015","journal-title":"Reprod. Sci."},{"issue":"1","key":"10.1016\/j.mce.2024.112290_bib11","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/S0015-0282(16)56037-3","article-title":"Estrogen and progesterone receptors in endometriotic tissue and endometrium: comparison according to localization and recurrence","volume":"60","author":"Bergqvist","year":"1993","journal-title":"Fertil. Steril."},{"issue":"11","key":"10.1016\/j.mce.2024.112290_bib12","doi-asserted-by":"crossref","first-page":"1915","DOI":"10.1093\/oxfordjournals.humrep.a137960","article-title":"Immunohistochemical analysis of oestrogen and progesterone receptors in endometriotic tissue and endometrium","volume":"8","author":"Bergqvist","year":"1993","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.mce.2024.112290_bib13","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/0003-2697(76)90527-3","article-title":"A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding","volume":"72","author":"Bradford","year":"1976","journal-title":"Anal. Biochem."},{"issue":"3","key":"10.1016\/j.mce.2024.112290_bib14","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1056\/NEJMra0804690","article-title":"Endometriosis","volume":"360","author":"Bulun","year":"2009","journal-title":"N. Engl. J. Med."},{"issue":"4","key":"10.1016\/j.mce.2024.112290_bib15","doi-asserted-by":"crossref","first-page":"1048","DOI":"10.1210\/er.2018-00242","volume":"40","author":"Bulun","year":"2019","journal-title":"Endometriosis. Endocr Rev."},{"issue":"11","key":"10.1016\/j.mce.2024.112290_bib16","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1038\/s41574-019-0245-z","article-title":"Rethinking mechanisms, diagnosis and management of endometriosis","volume":"15","author":"Chapron","year":"2019","journal-title":"Nat. Rev. Endocrinol."},{"issue":"8","key":"10.1016\/j.mce.2024.112290_bib17","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1016\/j.jfma.2013.04.007","article-title":"Baicalin ameliorates neuropathic pain by suppressing HDAC1 expression in the spinal cord of spinal nerve ligation rats","volume":"113","author":"Cherng","year":"2014","journal-title":"J. Formos. Med. Assoc."},{"issue":"6","key":"10.1016\/j.mce.2024.112290_bib18","doi-asserted-by":"crossref","first-page":"864","DOI":"10.1016\/j.rbmo.2009.10.001","article-title":"Differential regulation of Akt phosphorylation in endometriosis","volume":"19","author":"Cinar","year":"2009","journal-title":"Reprod. Biomed. Online"},{"issue":"12","key":"10.1016\/j.mce.2024.112290_bib19","doi-asserted-by":"crossref","first-page":"E1871","DOI":"10.1210\/jc.2013-1661","article-title":"Increased AKT or MEK1\/2 activity influences progesterone receptor levels and localization in endometriosis","volume":"98","author":"Eaton","year":"2013","journal-title":"J. Clin. Endocrinol. Metab."},{"issue":"12","key":"10.1016\/j.mce.2024.112290_bib20","doi-asserted-by":"crossref","first-page":"4561","DOI":"10.1210\/jc.2018-01227","article-title":"Progesterone receptor status predicts response to progestin therapy in endometriosis","volume":"103","author":"Flores","year":"2018","journal-title":"J. Clin. Endocrinol. Metab."},{"issue":"5","key":"10.1016\/j.mce.2024.112290_bib21","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1016\/j.gde.2005.08.002","article-title":"DNA methylation and histone modifications: teaming up to silence genes","volume":"15","author":"Fuks","year":"2005","journal-title":"Curr. Opin. Genet. Dev."},{"issue":"9","key":"10.1016\/j.mce.2024.112290_bib22","doi-asserted-by":"crossref","first-page":"2305","DOI":"10.1093\/nar\/gkg332","article-title":"The DNA methyltransferases associate with HP1 and the SUV39H1 histone methyltransferase","volume":"31","author":"Fuks","year":"2003","journal-title":"Nucleic Acids Res."},{"issue":"9447","key":"10.1016\/j.mce.2024.112290_bib23","first-page":"1789","article-title":"Endometriosis","volume":"364","author":"Giudice","year":"2004","journal-title":"Lancet (North Am. Ed.)"},{"issue":"2","key":"10.1016\/j.mce.2024.112290_bib24","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1159\/000096047","article-title":"Nuclear factor-kappab (NF-kappaB): an unsuspected major culprit in the pathogenesis of endometriosis that is still at large?","volume":"63","author":"Guo","year":"2007","journal-title":"Gynecol. Obstet. Invest."},{"issue":"3","key":"10.1016\/j.mce.2024.112290_bib25","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1095\/biolreprod.104.027235","article-title":"In vivo and in vitro regulation of Akt activation in human endometrial cells is estrogen dependent","volume":"71","author":"Guzeloglu","year":"2004","journal-title":"Biol. Reprod."},{"issue":"1","key":"10.1016\/j.mce.2024.112290_bib26","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1093\/humupd\/dmh007","article-title":"Apoptosis in human endometrium and endometriosis","volume":"10","author":"Harada","year":"2004","journal-title":"Hum. Reprod. Update"},{"key":"10.1016\/j.mce.2024.112290_bib27","doi-asserted-by":"crossref","first-page":"3140","DOI":"10.2741\/2302","article-title":"Apoptosis and endometriosis","volume":"12","author":"Harada","year":"2007","journal-title":"Front. Biosci."},{"issue":"2","key":"10.1016\/j.mce.2024.112290_bib28","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1097\/j.pain.0000000000001100","article-title":"TLR4 deficiency abrogated widespread tactile allodynia, but not widespread thermal hyperalgesia and trigeminal neuropathic pain after partial infraorbital nerve transection","volume":"159","author":"Hu","year":"2018","journal-title":"Pain"},{"issue":"3","key":"10.1016\/j.mce.2024.112290_bib29","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1093\/humrep\/dei372","article-title":"Drug-induced apoptosis was markedly attenuated in endometriotic stromal cells","volume":"21","author":"Izawa","year":"2006","journal-title":"Hum. Reprod."},{"issue":"11","key":"10.1016\/j.mce.2024.112290_bib30","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1177\/1933719110377118","article-title":"Promoter hypermethylation of progesterone receptor isoform B (PR-B) in adenomyosis and its rectification by a histone deacetylase inhibitor and a demethylation agent","volume":"17","author":"Jichan","year":"2010","journal-title":"Reprod. Sci."},{"issue":"12","key":"10.1016\/j.mce.2024.112290_bib31","doi-asserted-by":"crossref","first-page":"3272","DOI":"10.1093\/oxfordjournals.humrep.a135901","article-title":"Immunohistochemical characterization of proliferation, oestrogen receptor and progesterone receptor expression in endometriosis: comparison of eutopic and ectopic endometrium with normal cycling endometrium","volume":"10","author":"Jones","year":"1995","journal-title":"Hum. Reprod."},{"issue":"5","key":"10.1016\/j.mce.2024.112290_bib32","doi-asserted-by":"crossref","first-page":"1921","DOI":"10.1210\/en.2013-1951","article-title":"Activated AKT pathway promotes establishment of endometriosis","volume":"155","author":"Kim","year":"2014","journal-title":"Endocrinology"},{"issue":"2","key":"10.1016\/j.mce.2024.112290_bib33","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.tibs.2005.12.008","article-title":"Genomic DNA methylation: the mark and its mediators","volume":"31","author":"Klose","year":"2006","journal-title":"Trends Biochem. Sci."},{"issue":"3","key":"10.1016\/j.mce.2024.112290_bib34","doi-asserted-by":"crossref","first-page":"1126","DOI":"10.1016\/j.neuroimage.2009.12.045","article-title":"Genetics of primary cerebral gyrification: heritability of length, depth and area of primary sulci in an extended pedigree of Papio baboons","volume":"53","author":"Kochunov","year":"2010","journal-title":"Neuroimage"},{"issue":"4","key":"10.1016\/j.mce.2024.112290_bib35","doi-asserted-by":"crossref","first-page":"455","DOI":"10.3349\/ymj.2009.50.4.455","article-title":"Epigenetic cross-talk between DNA methylation and histone modifications in human cancers","volume":"50","author":"Kondo","year":"2009","journal-title":"Yonsei Med. J."},{"issue":"3","key":"10.1016\/j.mce.2024.112290_bib36","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1095\/biolreprod.114.119255","article-title":"Influence of AKT on progesterone action in endometrial diseases","volume":"91","author":"Lee","year":"2014","journal-title":"Biol. Reprod."},{"issue":"1\u20132","key":"10.1016\/j.mce.2024.112290_bib37","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1016\/j.mce.2010.11.022","article-title":"Selective inhibition of prostaglandin E2 receptors EP2 and EP4 inhibits invasion of human immortalized endometriotic epithelial and stromal cells through suppression of metalloproteinases","volume":"332","author":"Lee","year":"2011","journal-title":"Mol. Cell. Endocrinol."},{"issue":"14","key":"10.1016\/j.mce.2024.112290_bib38","doi-asserted-by":"crossref","first-page":"1192","DOI":"10.1016\/S0960-9822(03)00432-9","article-title":"Suv39h-mediated histone H3 lysine 9 methylation directs DNA methylation to major satellite repeats at pericentric heterochromatin","volume":"13","author":"Lehnertz","year":"2003","journal-title":"Curr. Biol."},{"issue":"6","key":"10.1016\/j.mce.2024.112290_bib39","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1210\/mend.13.6.0284","article-title":"Hoxa-10 regulates uterine stromal cell responsiveness to progesterone during implantation and decidualization in the mouse","volume":"13","author":"Lim","year":"1999","journal-title":"Mol. Endocrinol."},{"issue":"7","key":"10.1016\/j.mce.2024.112290_bib40","doi-asserted-by":"crossref","first-page":"625","DOI":"10.3109\/00016348709022068","article-title":"Altered progesterone\/estrogen receptor ratios in endometriosis. A comparative study of steroid receptors and morphology in endometriosis and endometrium","volume":"66","author":"Lyndrup","year":"1987","journal-title":"Acta Obstet. Gynecol. Scand."},{"issue":"15","key":"10.1016\/j.mce.2024.112290_bib41","doi-asserted-by":"crossref","DOI":"10.3390\/ijms20153822","article-title":"Progesterone and estrogen signaling in the endometrium: what goes wrong in endometriosis?","volume":"20","author":"Marquardt","year":"2019","journal-title":"Int. J. Mol. Sci."},{"issue":"7","key":"10.1016\/j.mce.2024.112290_bib42","doi-asserted-by":"crossref","first-page":"1606","DOI":"10.1093\/humrep\/dev108","article-title":"Co-operation between the AKT and ERK signaling pathways may support growth of deep endometriosis in a fibrotic microenvironment in vitro","volume":"30","author":"Matsuzaki","year":"2015","journal-title":"Hum. Reprod."},{"issue":"4","key":"10.1016\/j.mce.2024.112290_bib43","doi-asserted-by":"crossref","first-page":"897","DOI":"10.3892\/ijmm.2014.1637","article-title":"DNA methylation patterns of steroid receptor genes ESR1, ESR2 and PGR in deep endometriosis compromising the rectum","volume":"33","author":"Meyer","year":"2014","journal-title":"Int. J. Mol. Med."},{"issue":"11","key":"10.1016\/j.mce.2024.112290_bib44","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1093\/molehr\/gah249","article-title":"Bufalin induces apoptosis and the G0\/G1 cell cycle arrest of endometriotic stromal cells: a promising agent for the treatment of endometriosis","volume":"11","author":"Nasu","year":"2005","journal-title":"Mol. Hum. Reprod."},{"issue":"9","key":"10.1016\/j.mce.2024.112290_bib45","first-page":"1181","article-title":"Involvement of resistance to apoptosis in the pathogenesis of endometriosis","volume":"24","author":"Nasu","year":"2009","journal-title":"Histol. Histopathol."},{"issue":"6","key":"10.1016\/j.mce.2024.112290_bib46","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1111\/aogs.13156","article-title":"Progesterone resistance in endometriosis: origins, consequences and interventions","volume":"96","author":"Patel","year":"2017","journal-title":"Acta Obstet. Gynecol. Scand."},{"issue":"4","key":"10.1016\/j.mce.2024.112290_bib47","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1093\/humupd\/dmaa009","article-title":"Progesterone receptor ligands for the treatment of endometriosis: the mechanisms behind therapeutic success and failure","volume":"26","author":"Reis","year":"2020","journal-title":"Hum. Reprod. Update"},{"key":"10.1016\/j.mce.2024.112290_bib48","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1016\/S0002-9378(15)30003-X","article-title":"Peritoneal endometritis due to menstrual dissemination of endometrial tissu into the peritoneal cavity","volume":"14","author":"Sampson","year":"1927","journal-title":"Am. J. Obstet. Gynecol."},{"issue":"5","key":"10.1016\/j.mce.2024.112290_bib49","doi-asserted-by":"crossref","first-page":"1328","DOI":"10.1093\/humrep\/14.5.1328","article-title":"HOX gene expression is altered in the endometrium of women with endometriosis","volume":"14","author":"Taylor","year":"1999","journal-title":"Hum. Reprod."},{"issue":"10","key":"10.1016\/j.mce.2024.112290_bib50","doi-asserted-by":"crossref","first-page":"4701","DOI":"10.1210\/en.2009-0389","article-title":"Increased mitogen-activated protein kinase kinase\/extracellularly regulated kinase activity in human endometrial stromal fibroblasts of women with endometriosis reduces 3',5'-cyclic adenosine 5'-monophosphate inhibition of cyclin D1","volume":"150","author":"Velarde","year":"2009","journal-title":"Endocrinology"},{"issue":"7078","key":"10.1016\/j.mce.2024.112290_bib51","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1038\/nature04431","article-title":"The Polycomb group protein EZH2 directly controls DNA methylation","volume":"439","author":"Vire","year":"2006","journal-title":"Nature"},{"issue":"12","key":"10.1016\/j.mce.2024.112290_bib52","doi-asserted-by":"crossref","first-page":"6441","DOI":"10.1210\/jc.2005-0972","article-title":"Sulindac suppresses nuclear factor-kappaB activation and RANTES gene and protein expression in endometrial stromal cells from women with endometriosis","volume":"90","author":"Wieser","year":"2005","journal-title":"J. Clin. Endocrinol. Metab."},{"issue":"2","key":"10.1016\/j.mce.2024.112290_bib53","doi-asserted-by":"crossref","first-page":"106","DOI":"10.4161\/epi.1.2.2766","article-title":"Promoter hypermethylation of progesterone receptor isoform B (PR-B) in endometriosis","volume":"1","author":"Wu","year":"2006","journal-title":"Epigenetics"},{"issue":"1","key":"10.1016\/j.mce.2024.112290_bib54","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.fertnstert.2006.05.077","article-title":"Aberrant expression of deoxyribonucleic acid methyltransferases DNMT1, DNMT3A, and DNMT3B in women with endometriosis","volume":"87","author":"Wu","year":"2007","journal-title":"Fertil. Steril."},{"issue":"1","key":"10.1016\/j.mce.2024.112290_bib55","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/j.fertnstert.2007.06.008","article-title":"Prolonged stimulation with tumor necrosis factor-alpha induced partial methylation at PR-B promoter in immortalized epithelial-like endometriotic cells","volume":"90","author":"Wu","year":"2008","journal-title":"Fertil. Steril."},{"issue":"4","key":"10.1016\/j.mce.2024.112290_bib56","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1093\/humupd\/dmz005","article-title":"Endometriosis and nuclear receptors","volume":"25","author":"Yilmaz","year":"2019","journal-title":"Hum. Reprod. Update"},{"issue":"1","key":"10.1016\/j.mce.2024.112290_bib57","doi-asserted-by":"crossref","first-page":"E35","DOI":"10.1210\/jc.2011-1527","article-title":"Increased activation of the PI3K\/AKT pathway compromises decidualization of stromal cells from endometriosis","volume":"97","author":"Yin","year":"2012","journal-title":"J. Clin. Endocrinol. Metab."},{"issue":"5","key":"10.1016\/j.mce.2024.112290_bib58","doi-asserted-by":"crossref","first-page":"1839","DOI":"10.1016\/S0002-9440(10)63030-1","article-title":"Identification of an invasive, N-cadherin-expressing epithelial cell type in endometriosis using a new cell culture model","volume":"159","author":"Zeitvogel","year":"2001","journal-title":"Am. J. Pathol."},{"issue":"8","key":"10.1016\/j.mce.2024.112290_bib59","doi-asserted-by":"crossref","DOI":"10.3390\/ijms24086992","article-title":"Progesterone resistance in endometriosis: current evidence and putative mechanisms","volume":"24","author":"Zhang","year":"2023","journal-title":"Int. J. Mol. Sci."}],"container-title":["Molecular and Cellular Endocrinology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0303720724001461?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0303720724001461?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,9,7]],"date-time":"2024-09-07T07:34:48Z","timestamp":1725694488000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0303720724001461"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10]]},"references-count":59,"alternative-id":["S0303720724001461"],"URL":"https:\/\/doi.org\/10.1016\/j.mce.2024.112290","relation":{},"ISSN":["0303-7207"],"issn-type":[{"value":"0303-7207","type":"print"}],"subject":[],"published":{"date-parts":[[2024,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Dual inhibition of AKT and ERK1\/2 pathways restores the expression of progesterone Receptor-B in endometriotic lesions through epigenetic mechanisms","name":"articletitle","label":"Article Title"},{"value":"Molecular and Cellular Endocrinology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.mce.2024.112290","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"112290"}}