{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,6]],"date-time":"2026-09-06T11:10:00Z","timestamp":1788693000463,"version":"build-2803163510"},"reference-count":54,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100004703","name":"Guangxi University for Nationalities","doi-asserted-by":"publisher","award":["YY2026GYZ08"],"award-info":[{"award-number":["YY2026GYZ08"]}],"id":[{"id":"10.13039\/501100004703","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82360292"],"award-info":[{"award-number":["82360292"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004607","name":"Natural Science Foundation of Guangxi Province","doi-asserted-by":"publisher","award":["2025GXNSFAA0692909"],"award-info":[{"award-number":["2025GXNSFAA0692909"]}],"id":[{"id":"10.13039\/501100004607","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Molecular and Cellular Endocrinology"],"published-print":{"date-parts":[[2026,12]]},"DOI":"10.1016\/j.mce.2026.112894","type":"journal-article","created":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T23:26:58Z","timestamp":1786663618000},"page":"112894","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["An N-salicyloyl tryptamine derivative (compound 18) improves spermatogenic impairment in obese mice via regulating insulin resistance and enhancing Sertoli cell glycolysis"],"prefix":"10.1016","volume":"622","author":[{"given":"Zhenhui","family":"Fu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Changlei","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiumei","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongyi","family":"Pan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunqian","family":"Cai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaocan","family":"Lei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fenglian","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linlin","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"10","key":"10.1016\/j.mce.2026.112894_bib1","article-title":"Obesity: a doorway to a molecular path leading to infertility","volume":"14","author":"Ahmad","year":"2022","journal-title":"Cureus"},{"key":"10.1016\/j.mce.2026.112894_bib2","doi-asserted-by":"crossref","DOI":"10.3389\/fvets.2022.992877","article-title":"Effects of Pgam1-mediated glycolysis pathway in Sertoli cells on Spermatogonial stem cells based on transcriptomics and energy metabolomics","volume":"9","author":"An","year":"2022","journal-title":"Front. Vet. Sci."},{"key":"10.1016\/j.mce.2026.112894_bib3","doi-asserted-by":"crossref","DOI":"10.1016\/j.bioorg.2021.105255","article-title":"N-salicyloyl tryptamine derivatives as potential therapeutic agents for Alzheimer's disease with neuroprotective effects","volume":"115","author":"Bai","year":"2021","journal-title":"Bioorg. Chem."},{"issue":"10440","key":"10.1016\/j.mce.2026.112894_bib4","doi-asserted-by":"crossref","first-page":"2057","DOI":"10.1016\/S0140-6736(24)00550-6","article-title":"Global fertility in 204 countries and territories, 1950\u20132021, with forecasts to 2100: a comprehensive demographic analysis for the global Burden of disease study 2021","volume":"403","author":"Bhattacharjee","year":"2024","journal-title":"Lancet"},{"issue":"20","key":"10.1016\/j.mce.2026.112894_bib5","doi-asserted-by":"crossref","DOI":"10.3390\/ijms262010168","article-title":"Differential expression of complement pathway components in unexplained infertility versus Male factor infertility: insights from an exploratory pilot study","volume":"26","author":"Brennan","year":"2025","journal-title":"Int. J. Mol. Sci."},{"issue":"2","key":"10.1016\/j.mce.2026.112894_bib6","doi-asserted-by":"crossref","DOI":"10.3390\/ijms26020788","article-title":"Protection strategies against palmitic acid-induced lipotoxicity in metabolic syndrome and related diseases","volume":"26","author":"Ceja-Galicia","year":"2025","journal-title":"Int. J. Mol. Sci."},{"issue":"8","key":"10.1016\/j.mce.2026.112894_bib7","doi-asserted-by":"crossref","DOI":"10.1111\/and.13323","article-title":"Melatonin appears to protect against steroidogenic collapse in both mice fed with high\u2010fat diet and H2O2\u2010treated TM3 cells","volume":"51","author":"Chen","year":"2019","journal-title":"Andrologia"},{"issue":"22","key":"10.1016\/j.mce.2026.112894_bib8","doi-asserted-by":"crossref","DOI":"10.1002\/advs.202310110","article-title":"Gut\u2010derived exosomes mediate the microbiota dysbiosis\u2010induced spermatogenesis impairment by targeting meioc in mice","volume":"11","author":"Chen","year":"2024","journal-title":"Adv. Sci."},{"issue":"3","key":"10.1016\/j.mce.2026.112894_bib9","article-title":"Ablating astrocyte insulin receptors leads to delayed puberty and hypogonadism in mice","volume":"17","author":"Daneman","year":"2019","journal-title":"PLoS Biol."},{"key":"10.1016\/j.mce.2026.112894_bib10","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2013\/970370","article-title":"Insulin deprivation decreases caspase-dependent apoptotic signaling in cultured rat sertoli cells","volume":"2013","author":"Dias","year":"2013","journal-title":"ISRN Urology."},{"issue":"4","key":"10.1016\/j.mce.2026.112894_bib11","article-title":"Perinatal overnutrition exacerbates adipose tissue inflammation caused by high-fat feeding in C57BL\/6J mice","volume":"10","author":"Dileepan","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.mce.2026.112894_bib12","first-page":"193","article-title":"Design, synthesis and bioactivity study of N-salicyloyl tryptamine derivatives as multifunctional agents for the treatment of neuroinflammation","author":"Fan","year":"2020","journal-title":"Eur. J. Med. Chem."},{"issue":"2","key":"10.1016\/j.mce.2026.112894_bib13","doi-asserted-by":"crossref","DOI":"10.3390\/nu17020241","article-title":"Pathophysiological role of neutrophil extracellular traps in diet-induced obesity and metabolic syndrome in animal models","volume":"17","author":"Feje\u0161","year":"2025","journal-title":"Nutrients"},{"key":"10.1016\/j.mce.2026.112894_bib14","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2022.102380","article-title":"Protein palmitoylation-mediated palmitic acid sensing causes blood-testis barrier damage via inducing ER stress","volume":"54","author":"Ge","year":"2022","journal-title":"Redox Biol."},{"key":"10.1016\/j.mce.2026.112894_bib15","doi-asserted-by":"crossref","DOI":"10.1016\/j.taap.2024.116929","article-title":"Exposure to toxicologically relevant atrazine concentrations impair the glycolytic function of mouse sertoli cells through the downregulation of lactate dehydrogenase","volume":"486","author":"Gomes-Andrade","year":"2024","journal-title":"Toxicol. Appl. Pharmacol."},{"issue":"1","key":"10.1016\/j.mce.2026.112894_bib16","doi-asserted-by":"crossref","DOI":"10.1186\/s12958-020-00625-9","article-title":"Down regulating PHGDH affects the lactate production of sertoli cells in varicocele","volume":"18","author":"Guo","year":"2020","journal-title":"Reprod. Biol. Endocrinol."},{"key":"10.1016\/j.mce.2026.112894_bib17","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2023.115063","article-title":"Enhanced autophagy reversed aflatoxin B1-induced decrease in lactate secretion of dairy goat sertoli cells","volume":"259","author":"Han","year":"2023","journal-title":"Ecotoxicol. Environ. Saf."},{"issue":"6","key":"10.1016\/j.mce.2026.112894_bib18","doi-asserted-by":"crossref","first-page":"2781","DOI":"10.1007\/s10787-023-01242-9","article-title":"Salsalate: a pleotropic anti-inflammatory drug in the treatment of diabetes, obesity, and metabolic diseases","volume":"31","author":"Hasan","year":"2023","journal-title":"Inflammopharmacology"},{"issue":"1","key":"10.1016\/j.mce.2026.112894_bib19","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.yexcr.2003.11.012","article-title":"HST-1\/FGF-4 protects male germ cells from apoptosis under heat-stress condition","volume":"294","author":"Hirai","year":"2004","journal-title":"Exp. Cell Res."},{"issue":"1","key":"10.1016\/j.mce.2026.112894_bib20","doi-asserted-by":"crossref","DOI":"10.1186\/s12894-018-0360-5","article-title":"Obesity impairs male fertility through long-term effects on spermatogenesis","volume":"18","author":"Jia","year":"2018","journal-title":"BMC Urol."},{"issue":"11","key":"10.1016\/j.mce.2026.112894_bib21","doi-asserted-by":"crossref","DOI":"10.3390\/jcm14113930","article-title":"Male infertility and reduced life expectancy: epidemiology, mechanisms, and clinical implications","volume":"14","author":"Kaltsas","year":"2025","journal-title":"J. Clin. Med."},{"issue":"9","key":"10.1016\/j.mce.2026.112894_bib22","doi-asserted-by":"crossref","DOI":"10.3390\/biomedicines13092054","article-title":"Progress in investigating the impact of obesity on Male reproductive function","volume":"13","author":"Kang","year":"2025","journal-title":"Biomedicines"},{"issue":"1","key":"10.1016\/j.mce.2026.112894_bib23","doi-asserted-by":"crossref","DOI":"10.1186\/s13287-025-04532-x","article-title":"Human embryonic stem cell-derived Sertoli cells as an immune modulator of cell transplantation therapy in a diabetic mice model","volume":"16","author":"Lee","year":"2025","journal-title":"Stem Cell Res. Ther."},{"issue":"1","key":"10.1016\/j.mce.2026.112894_bib24","doi-asserted-by":"crossref","DOI":"10.1186\/s12944-025-02768-3","article-title":"Imidazole propionate ameliorates lipid metabolism in adipocytes to attenuate high-fat diet-induced obesity via PPAR signaling pathway","volume":"24","author":"Lin","year":"2025","journal-title":"Lipids Health Dis."},{"key":"10.1016\/j.mce.2026.112894_bib25","first-page":"229","article-title":"Design, synthesis, and biological evaluation of carbamate derivatives of N-salicyloyl tryptamine as multifunctional agents for the treatment of Alzheimer's disease","author":"Liu","year":"2022","journal-title":"Eur. J. Med. Chem."},{"issue":"1","key":"10.1016\/j.mce.2026.112894_bib27","doi-asserted-by":"crossref","DOI":"10.1038\/s42003-025-09094-5","article-title":"Nicotinamide mononucleotide treatment improves spermatogenesis in obese mice by reducing lysine acetylation of lactate dehydrogenase C","volume":"8","author":"Liu","year":"2025","journal-title":"Commun. Biol."},{"issue":"1","key":"10.1016\/j.mce.2026.112894_bib26","doi-asserted-by":"crossref","DOI":"10.1186\/s13287-024-03893-z","article-title":"Microenvironment of spermatogonial stem cells: a key factor in the regulation of spermatogenesis","volume":"15","author":"Liu","year":"2024","journal-title":"Stem Cell Res. Ther."},{"issue":"13","key":"10.1016\/j.mce.2026.112894_bib29","doi-asserted-by":"crossref","DOI":"10.1002\/mnfr.202200524","article-title":"Icariin ameliorates spermatogenesis disorder in Obese mice induced by high-fat diet through regulating the glycolytic pathway","volume":"67","author":"Luo","year":"2023","journal-title":"Mol. Nutr. Food Res."},{"issue":"16","key":"10.1016\/j.mce.2026.112894_bib28","doi-asserted-by":"crossref","DOI":"10.3390\/molecules24162966","article-title":"Soy isoflavones improve the spermatogenic defects in diet-induced obesity rats through Nrf2\/HO-1 pathway","volume":"24","author":"Luo","year":"2019","journal-title":"Molecules"},{"key":"10.1016\/j.mce.2026.112894_bib30","article-title":"Therapeutic mechanisms of Lycii Fructus in male infertility: a comprehensive review","volume":"16","author":"Ma","year":"2025","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.mce.2026.112894_bib31","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2025.1702791","article-title":"Beyond body mass index: the role of fat distribution in male sperm quality","volume":"16","author":"Ma","year":"2025","journal-title":"Front. Endocrinol."},{"issue":"1","key":"10.1016\/j.mce.2026.112894_bib32","doi-asserted-by":"crossref","DOI":"10.1186\/s41232-022-00203-z","article-title":"Diet-induced obesity impairs spermatogenesis: the critical role of NLRP3 in Sertoli cells","volume":"42","author":"Mu","year":"2022","journal-title":"Inflamm. Regen."},{"issue":"5","key":"10.1016\/j.mce.2026.112894_bib33","doi-asserted-by":"crossref","DOI":"10.1177\/15579883251380206","article-title":"Correlation of A body shape index and body roundness index as novel anthropometric indices with semen analysis parameters and IVF outcomes","volume":"19","author":"Nikolic","year":"2025","journal-title":"Am. J. Mens Health"},{"key":"10.1016\/j.mce.2026.112894_bib34","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2021.773820","article-title":"Obesity-induced insulin resistance is mediated by high uric acid in Obese children and adolescents","volume":"12","author":"Niu","year":"2021","journal-title":"Front. Endocrinol."},{"issue":"2","key":"10.1016\/j.mce.2026.112894_bib35","doi-asserted-by":"crossref","DOI":"10.1097\/MD.0000000000036898","article-title":"Understanding apoptosis in sickle cell anemia patients: mechanisms and implications","volume":"103","author":"Obeagu","year":"2024","journal-title":"Medicine"},{"key":"10.1016\/j.mce.2026.112894_bib36","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.theriogenology.2022.02.029","article-title":"Melatonin supplementation preserves testicular function by attenuating lactate production and oxidative stress in high fat diet-induced obese rat model","volume":"187","author":"Saidi","year":"2022","journal-title":"Theriogenology"},{"issue":"5","key":"10.1016\/j.mce.2026.112894_bib37","doi-asserted-by":"crossref","DOI":"10.1016\/j.acthis.2023.152046","article-title":"Immunohistochemical analysis of the vimentin filaments in Sertoli cells is a powerful tool for the prediction of spermatogenic dysfunction","volume":"125","author":"Saito","year":"2023","journal-title":"Acta Histochem."},{"key":"10.1016\/j.mce.2026.112894_bib38","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2025.103669","article-title":"Dysregulation of sphingolipid and cholesterol homeostasis imposes oxidative stress in human spermatozoa","volume":"84","author":"Serafini","year":"2025","journal-title":"Redox Biol."},{"issue":"1","key":"10.1016\/j.mce.2026.112894_bib39","doi-asserted-by":"crossref","DOI":"10.1186\/s12610-025-00289-8","article-title":"Obesity induced by a high-fat diet regulates the MYC\u2012PPIL1 network in the mediation of asthenozoospermia","volume":"35","author":"Shi","year":"2025","journal-title":"Basic Clin. Androl."},{"issue":"11","key":"10.1016\/j.mce.2026.112894_bib40","doi-asserted-by":"crossref","first-page":"2146","DOI":"10.1021\/acschemneuro.3c00149","article-title":"Neuroprotective effects of an N-Salicyloyl tryptamine derivative against cerebral Ischemia\/reperfusion injury","volume":"14","author":"Su","year":"2023","journal-title":"ACS Chem. Neurosci."},{"issue":"6","key":"10.1016\/j.mce.2026.112894_bib41","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1097\/MOU.0000000000001339","article-title":"Impact of lifestyle and environmental factors on fertility","volume":"35","author":"Szab\u00f3","year":"2025","journal-title":"Curr. Opin. Urol."},{"issue":"1","key":"10.1016\/j.mce.2026.112894_bib42","doi-asserted-by":"crossref","DOI":"10.1186\/s13578-025-01478-8","article-title":"Ssrp governs germline development independent of the FACT complex in Drosophila spermatogenesis","volume":"15","author":"Tan","year":"2025","journal-title":"Cell Biosci."},{"issue":"11","key":"10.1016\/j.mce.2026.112894_bib44","doi-asserted-by":"crossref","DOI":"10.1038\/s41419-023-06162-8","article-title":"Pyrroloquinoline quinone inhibits PCSK9-NLRP3 mediated pyroptosis of Leydig cells in obese mice","volume":"14","author":"Wang","year":"2023","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.mce.2026.112894_bib43","doi-asserted-by":"crossref","DOI":"10.1016\/j.bioorg.2022.105993","article-title":"Discovery of carbamate-based N-salicyloyl tryptamine derivatives as novel pleiotropic agents for the treatment of Alzheimer's disease","volume":"127","author":"Wang","year":"2022","journal-title":"Bioorg. Chem."},{"key":"10.1016\/j.mce.2026.112894_bib45","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2025.114280","article-title":"Icariin inhibition of NLRP3 mediated Leydig cell pyroptosis and insulin resistance ameliorates spermatogenesis disorders in obese mice","volume":"151","author":"Wei","year":"2025","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.mce.2026.112894_bib46","first-page":"278","article-title":"Design, synthesis and biological evaluation of N-salicyloyl tryptamine derivatives as multifunctional neuroprotectants for the treatment of ischemic stroke","author":"Wu","year":"2024","journal-title":"Eur. J. Med. Chem."},{"issue":"1","key":"10.1016\/j.mce.2026.112894_bib47","doi-asserted-by":"crossref","DOI":"10.1186\/s40659-025-00661-y","article-title":"Disrupted inhibin B synthesis due to Sox9 hyper-palmitoylation in Sertoli cells impairs spermatogenesis via paracrine effects","volume":"59","author":"Xiang","year":"2025","journal-title":"Biol. Res."},{"key":"10.1016\/j.mce.2026.112894_bib48","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2022.1021263","article-title":"Atlas of metabolism reveals palmitic acid results in mitochondrial dysfunction and cell apoptosis by inhibiting fatty acid \u03b2-oxidation in Sertoli cells","volume":"13","author":"Xu","year":"2022","journal-title":"Front. Endocrinol."},{"issue":"9","key":"10.1016\/j.mce.2026.112894_bib49","article-title":"miR-1285-3p targets TPI1 to regulate the glycolysis metabolism signaling pathway of Tibetan sheep Sertoli cells","volume":"17","author":"Yenugu","year":"2022","journal-title":"PLoS One"},{"issue":"12","key":"10.1016\/j.mce.2026.112894_bib50","doi-asserted-by":"crossref","first-page":"18","DOI":"10.29063\/ajrh2025\/v29i12.2","article-title":"Impact of insulin resistance on sperm parameters and serum osteocalcin levels: a prospective cross-sectional comparative study","volume":"29","author":"Yilmaz","year":"2025","journal-title":"Afr. J. Reprod. Health"},{"issue":"1","key":"10.1016\/j.mce.2026.112894_bib51","doi-asserted-by":"crossref","DOI":"10.1186\/s12967-025-07251-2","article-title":"Effects of a two-week modified ketogenic diet on circulating lipoprotein subclasses, GDF15, and FGF21 in obese adults","volume":"23","author":"Zhang","year":"2025","journal-title":"J. Transl. Med."},{"issue":"13","key":"10.1016\/j.mce.2026.112894_bib52","doi-asserted-by":"crossref","first-page":"2484","DOI":"10.1021\/acschemneuro.4c00060","article-title":"N-Salicyloyl tryptamine derivatives as potent neuroinflammation inhibitors by constraining microglia activation via a STAT3 pathway","volume":"15","author":"Zhao","year":"2024","journal-title":"ACS Chem. Neurosci."},{"issue":"1","key":"10.1016\/j.mce.2026.112894_bib53","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1530\/REP-13-0299","article-title":"Wt1 deficiency causes undifferentiated spermatogonia accumulation and meiotic progression disruption in neonatal mice","volume":"147","author":"Zheng","year":"2014","journal-title":"Reproduction"},{"issue":"8","key":"10.1016\/j.mce.2026.112894_bib54","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1002\/mrd.23402","article-title":"Characterization of rodent Sertoli cell primary cultures","volume":"87","author":"Zomer","year":"2020","journal-title":"Mol. Reprod. Dev."}],"container-title":["Molecular and Cellular Endocrinology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0303720726001711?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0303720726001711?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,6]],"date-time":"2026-09-06T10:12:15Z","timestamp":1788689535000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0303720726001711"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,12]]},"references-count":54,"alternative-id":["S0303720726001711"],"URL":"https:\/\/doi.org\/10.1016\/j.mce.2026.112894","relation":{},"ISSN":["0303-7207"],"issn-type":[{"value":"0303-7207","type":"print"}],"subject":[],"published":{"date-parts":[[2026,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"An N-salicyloyl tryptamine derivative (compound 18) improves spermatogenic impairment in obese mice via regulating insulin resistance and enhancing Sertoli cell glycolysis","name":"articletitle","label":"Article Title"},{"value":"Molecular and Cellular Endocrinology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.mce.2026.112894","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"112894"}}