{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T15:58:07Z","timestamp":1791561487440,"version":"4.3.4"},"reference-count":83,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2027,2,1]],"date-time":"2027-02-01T00:00:00Z","timestamp":1801440000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2027,2,1]],"date-time":"2027-02-01T00:00:00Z","timestamp":1801440000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2027,2,1]],"date-time":"2027-02-01T00:00:00Z","timestamp":1801440000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2027,2,1]],"date-time":"2027-02-01T00:00:00Z","timestamp":1801440000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2027,2,1]],"date-time":"2027-02-01T00:00:00Z","timestamp":1801440000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2027,2,1]],"date-time":"2027-02-01T00:00:00Z","timestamp":1801440000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2027,2,1]],"date-time":"2027-02-01T00:00:00Z","timestamp":1801440000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100006668","name":"Fund for Scientific and Technological Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006668","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100021778","name":"Agencia Nacional de Promoci\u00f3n de la Investigaci\u00f3n, el Desarrollo Tecnol\u00f3gico y la Innovaci\u00f3n","doi-asserted-by":"publisher","award":["PICT-2021-I-INVI number 00253"],"award-info":[{"award-number":["PICT-2021-I-INVI number 00253"]}],"id":[{"id":"10.13039\/501100021778","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005746","name":"Universidad Nacional del Litoral","doi-asserted-by":"publisher","award":["CAI +D number 50620190100008LI-2021"],"award-info":[{"award-number":["CAI +D number 50620190100008LI-2021"]}],"id":[{"id":"10.13039\/501100005746","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Molecular and Cellular Endocrinology"],"published-print":{"date-parts":[[2027,2]]},"DOI":"10.1016\/j.mce.2026.112921","type":"journal-article","created":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T06:53:50Z","timestamp":1791269630000},"page":"112921","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Skeletal muscle redox imbalance and fibrosis in rats fed short- and long-term sucrose-rich diet: preventive effects of chia seed (Salvia hispanica L.)"],"prefix":"10.1016","volume":"624","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8491-2458","authenticated-orcid":false,"given":"Paola G.","family":"Illesca","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4368-4102","authenticated-orcid":false,"given":"Mar\u00eda Eugenia","family":"Oliva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1309-6238","authenticated-orcid":false,"given":"Noelia","family":"Villafa\u00f1e","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paola","family":"Ingaramo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6008-5614","authenticated-orcid":false,"given":"Mar\u00eda Eugenia","family":"D'Alessandro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.mce.2026.112921_bib1","doi-asserted-by":"crossref","first-page":"3845","DOI":"10.3390\/ijms21113845","article-title":"Implications of skeletal muscle extracellular matrix remodeling in metabolic disorders: diabetes perspective","volume":"21","author":"Ahmad","year":"2020","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.mce.2026.112921_bib2","doi-asserted-by":"crossref","DOI":"10.3390\/cells7100148","article-title":"Multifaceted interweaving between extracellular matrix, insulin resistance, and skeletal muscle","volume":"7","author":"Ahmad","year":"2018","journal-title":"Cells"},{"key":"10.1016\/j.mce.2026.112921_bib3","doi-asserted-by":"crossref","DOI":"10.1016\/j.mce.2024.112438","article-title":"Salvia hispanica L. (chia) seed have beneficial effects upon visceral adipose tissues extracellular matrix disorders and inflammation developed in a sucrose-rich diet-induced adiposity rodent model","volume":"597","author":"Aiassa","year":"2025","journal-title":"Mol. Cell. Endocrinol."},{"key":"10.1016\/j.mce.2026.112921_bib4","author":"Alberti","year":"2009","journal-title":"Circulation"},{"key":"10.1016\/j.mce.2026.112921_bib5","doi-asserted-by":"crossref","DOI":"10.25122\/jml-2022-0157","article-title":"Lipotoxicity-related sarcopenia: a review","author":"Aldahhan","year":"2022","journal-title":"J. Med. Life."},{"key":"10.1016\/j.mce.2026.112921_bib6","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1172\/JCI37048","article-title":"Mitochondrial H2O2 emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans","volume":"119","author":"Anderson","year":"2009","journal-title":"J. Clin. Investig."},{"key":"10.1016\/j.mce.2026.112921_bib7","doi-asserted-by":"crossref","DOI":"10.3389\/fphys.2019.00372","article-title":"A short-term high-fat diet alters glutathione levels and IL-6 gene expression in oxidative skeletal muscles of young rats","volume":"10","author":"Andrich","year":"2019","journal-title":"Front. Physiol."},{"key":"10.1016\/j.mce.2026.112921_bib8","series-title":"Molecular Aspects of Medicine","first-page":"219","article-title":"Role of 4-hydroxynonenal in stress-mediated apoptosis signaling","author":"Awasthi","year":"2003"},{"key":"10.1016\/j.mce.2026.112921_bib9","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1152\/ajpendo.00202.2005","article-title":"Increased collagen content in insulin-resistant skeletal muscle","volume":"290","author":"Berria","year":"2006","journal-title":"Am. J. Physiol. Endocrinol. Metab."},{"key":"10.1016\/j.mce.2026.112921_bib10","first-page":"789","article-title":"Mitochondrial dysfunction results from oxidative stress in the skeletal muscle of diet-induced insulin-resistant mice","volume":"118","author":"Bonnard","year":"2008","journal-title":"J. Clin. Investig."},{"key":"10.1016\/j.mce.2026.112921_bib11","doi-asserted-by":"crossref","first-page":"2677","DOI":"10.1210\/en.2011-2147","article-title":"Early mitochondrial adaptations in skeletal muscle to diet-induced obesity are strain dependent and determine oxidative stress and energy expenditure but not insulin sensitivity","volume":"153","author":"Boudina","year":"2012","journal-title":"Endocrinology"},{"key":"10.1016\/j.mce.2026.112921_bib12","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/0003-2697(76)90527-3","article-title":"A rapid and sensitive method for the quantitation microgram quantities of protein utilizing the principle of protein-dye binding","volume":"72","author":"Bradford","year":"1976","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.mce.2026.112921_bib13","doi-asserted-by":"crossref","first-page":"648","DOI":"10.3945\/jn.109.111179","article-title":"The developmental origins , mechanisms , and implications of metabolic syndrome 1 \u2013 3","volume":"140","author":"Bruce","year":"2010","journal-title":"J. Nutr."},{"key":"10.1016\/j.mce.2026.112921_bib14","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1016\/j.cmet.2023.02.003","article-title":"The global burden of metabolic disease: data from 2000 to 2019","volume":"35","author":"Chew","year":"2023","journal-title":"Cell Metab."},{"key":"10.1016\/j.mce.2026.112921_bib15","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1093\/jn\/133.1.127","article-title":"Muscle lipid metabolism and insulin secretion are altered in Insulin- resistant rats fed a high sucrose diet","volume":"133","author":"Chicco","year":"2003","journal-title":"J. Nutr."},{"key":"10.1016\/j.mce.2026.112921_bib16","doi-asserted-by":"crossref","DOI":"10.1155\/omcl\/5709962","article-title":"Passiflora edulis f. flavicarpa extract prevents muscle atrophy and insulin resistance in high-fat diet\u2013induced Obese rats via regulating the Nrf2, NF-\u03baB, and IRS-1\/PI3K\/AKT signaling pathways","volume":"2026","author":"Chobsuay","year":"2026","journal-title":"Oxid. Med. Cell. Longev."},{"key":"10.1016\/j.mce.2026.112921_bib17","article-title":"Extrapancreatic effects of incretin hormones: evidence for weight-independent changes in morphological aspects and oxidative status in insulin-sensitive organs of the obese nondiabetic Zucker rat (ZFR)","volume":"4","author":"Colin","year":"2016","journal-title":"Phys. Rep."},{"key":"10.1016\/j.mce.2026.112921_bib18","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/srep37278","article-title":"A high-fat high-sucrose diet rapidly Alters muscle integrity, inflammation and gut microbiota in Male rats","volume":"6","author":"Collins","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.mce.2026.112921_bib19","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.plefa.2017.06.002","article-title":"Dietary Salba (Salvia hispanica L) improves the altered metabolic fate of glucose and reduces increased collagen deposition in the heart of insulin- resistant rats","volume":"121","author":"Creus","year":"2017","journal-title":"Prostaglandins Leukot. Essent. Fatty Acids"},{"key":"10.1016\/j.mce.2026.112921_bib20","article-title":"Dietary Salvia hispanica L . reduces cardiac oxidative stress of dyslipemic insulin-resistant rats","volume":"45","author":"Creus","year":"2020","journal-title":"Am. Physiol. Nutr. Metab."},{"key":"10.1016\/j.mce.2026.112921_bib21","article-title":"Dietary Salvia hispanica L. seed counteracted kidney failure in experimental metabolic syndrome","author":"Creus","year":"2022","journal-title":"J. Food Nutr. Metab."},{"key":"10.1016\/j.mce.2026.112921_bib22","doi-asserted-by":"crossref","DOI":"10.3390\/ijms26115151","article-title":"Quercetin, kaempferol and Capsaicin counteract the TGF-\u03b21-Induced upregulation of \u03b1SMA and Collagen in myoblasts","volume":"26","author":"Cuijpers","year":"2025","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.mce.2026.112921_bib24","doi-asserted-by":"crossref","first-page":"1299","DOI":"10.1039\/C4FO00903G","article-title":"Time course of adipose tissue dysfunction associated with antioxidant defense, inflammatory cytokines and oxidative stress in dyslipemic insulin resistant rats","volume":"6","author":"D'Alessandro","year":"2015","journal-title":"Food Funct."},{"key":"10.1016\/j.mce.2026.112921_bib23","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1007\/s12192-015-0642-8","article-title":"Omega-3 fatty acids differentially modulate enzymatic anti-oxidant systems in skeletal muscle cells","volume":"21","author":"da Silva","year":"2016","journal-title":"Cell Stress Chaperones"},{"key":"10.1016\/j.mce.2026.112921_bib25","doi-asserted-by":"crossref","DOI":"10.3390\/ijms22052639","article-title":"Adipokines, myokines, and hepatokines: crosstalk and metabolic repercussions","author":"de Oliveira dos Santos","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.mce.2026.112921_bib26","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1159\/000534610","article-title":"Effects of full-spectrum cannabis oil with a cannabidiol:tetrahydrocannabinol 2:1 ratio on the mechanisms involved in hepatic steatosis and oxidative stress in rats fed a sucrose-rich diet","volume":"6","author":"Degrave","year":"2023","journal-title":"Med. Cannabis Cannabinoids"},{"key":"10.1016\/j.mce.2026.112921_bib27","doi-asserted-by":"crossref","DOI":"10.1530\/JOE-16-0598","article-title":"Skeletal muscle insulin resistance : role of mitochondria and other ROS sources","author":"Di Meo","year":"2017","journal-title":"J. Endocrinol."},{"key":"10.1016\/j.mce.2026.112921_bib28","doi-asserted-by":"crossref","DOI":"10.1007\/s11130-025-01331-w","article-title":"Unlocking the potential of Chia intake in the management of metabolic syndrome and its risk conditions: a narrative review","author":"Egea","year":"2025","journal-title":"Plant Foods Hum. Nutr."},{"key":"10.1016\/j.mce.2026.112921_bib29","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/0003-9861(59)90090-6","article-title":"Tissue sufhydry groups","volume":"82","author":"Ellman","year":"1959","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.mce.2026.112921_bib30","doi-asserted-by":"crossref","first-page":"15740","DOI":"10.3390\/ijms140815740","article-title":"Insulin-dependent H2O2 production is higher in muscle fibers of mice fed with a high-fat diet","volume":"14","author":"Espinosa","year":"2013","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.mce.2026.112921_bib31","doi-asserted-by":"crossref","first-page":"1789","DOI":"10.1017\/S0007114513001311","article-title":"Effects of long-term administration of saturated and n-3 fatty acid-rich diets on lipid utilisation and oxidative stress in rat liver and muscle tissues","volume":"110","author":"Feillet-Coudray","year":"2013","journal-title":"Br. J. Nutr."},{"key":"10.1016\/j.mce.2026.112921_bib32","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1016\/j.freeradbiomed.2008.11.020","article-title":"Oxidative stress in rats fed a high-fat high-sucrose diet and preventive effect of polyphenols: involvement of mitochondrial and NAD(P)H oxidase systems","volume":"46","author":"Feillet-Coudray","year":"2009","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.mce.2026.112921_bib35","doi-asserted-by":"crossref","DOI":"10.1016\/j.physbeh.2024.114776","article-title":"Changes in cerebral cortex redox status and cognitive performance in short- and long-term high-sucrose diet fed rats","volume":"290","author":"Ferreira","year":"2025","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.mce.2026.112921_bib33","doi-asserted-by":"crossref","DOI":"10.1016\/j.jff.2019.103775","article-title":"Salvia hispanica L. (chia) seed improves skeletal muscle lipotoxicity and insulin sensitivity in rats fed a sucrose-rich diet by modulating intramuscular lipid metabolism","volume":"66","author":"Ferreira","year":"2020","journal-title":"J. Funct.Foods"},{"key":"10.1016\/j.mce.2026.112921_bib36","article-title":"Dietary Salba (Salvia hispanica L.) ameliorates the adipose tissue dysfunction of dyslipemic insulin-resistant rats through mechanisms involving oxidative stress, inflammatory cytokines and peroxisome proliferator-activated receptor \u03b3","author":"Ferreira","year":"2016","journal-title":"Eur. J. Nutr."},{"key":"10.1016\/j.mce.2026.112921_bib37","doi-asserted-by":"crossref","DOI":"10.3390\/antiox12020299","article-title":"Age-dependent skeletal muscle mitochondrial response to short-term increased dietary fructose","volume":"12","author":"Gatto","year":"2023","journal-title":"Antioxidants"},{"key":"10.1016\/j.mce.2026.112921_bib38","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.mam.2018.03.005","article-title":"More than a syllable in fib-ROS-is: the role of ROS on the fibrotic extracellular matrix and on cellular contacts","volume":"63","author":"Grosche","year":"2018","journal-title":"Mol. Aspect. Med."},{"key":"10.1016\/j.mce.2026.112921_bib39","doi-asserted-by":"crossref","DOI":"10.1016\/j.tcm.2015.10.004","article-title":"Metabolic syndrome update","author":"Grundy","year":"2016","journal-title":"Trends Cardiovasc. Med."},{"key":"10.1016\/j.mce.2026.112921_bib40","doi-asserted-by":"crossref","first-page":"94","DOI":"10.4239\/wjd.v3.i5.94","article-title":"Curcumin attenuates Nrf2 signaling defect, oxidative stress in muscle and glucose intolerance in high fat diet-fed mice","volume":"3","author":"He","year":"2012","journal-title":"World J. Diabetes"},{"key":"10.1016\/j.mce.2026.112921_bib41","doi-asserted-by":"crossref","DOI":"10.1002\/biof.2087","article-title":"Salvia hispanica L. (chia) seed improves redox state and reverts extracellular matrix collagen deposition in skeletal muscle of sucrose-rich diet-fed rats","volume":"51","author":"Illesca","year":"2025","journal-title":"Biofactors"},{"key":"10.1016\/j.mce.2026.112921_bib42","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2021.118729","article-title":"Altered uterine angiogenesis in rats treated with a glyphosate-based herbicide","volume":"296","author":"Ingaramo","year":"2022","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.mce.2026.112921_bib43","doi-asserted-by":"crossref","DOI":"10.1016\/j.fct.2019.110832","article-title":"Acute uterine effects and long-term reproductive alterations in postnatally exposed female rats to a mixture of commercial formulations of endosulfan and glyphosate","volume":"134","author":"Ingaramo","year":"2019","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.mce.2026.112921_bib44","doi-asserted-by":"crossref","first-page":"416","DOI":"10.2337\/db10-1116","article-title":"Diet-induced muscle insulin resistance is associated with extracellular matrix remodeling and interaction with integrin \u03b12\u03b2 1in mice","volume":"60","author":"Kang","year":"2011","journal-title":"Diabetes"},{"key":"10.1016\/j.mce.2026.112921_bib45","article-title":"The impact of a short-term high-fat diet on mitochondrial respiration, reactive oxygen species production, and dynamics in oxidative and glycolytic skeletal muscles of young rats","volume":"6","author":"Leduc-Gaudet","year":"2018","journal-title":"Phys. Rep."},{"key":"10.1016\/j.mce.2026.112921_bib46","article-title":"Skeletal muscle metabolism in health and disease: mechanisms, interventions, and clinical perspectives","author":"Lin","year":"2026","journal-title":"iScience"},{"key":"10.1016\/j.mce.2026.112921_bib47","article-title":"The role and mechanism of Nrf2 in ameliorating oxidative stress and inflammation in IR mice by aerobic exercise","volume":"27","author":"Liu","year":"2026","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.mce.2026.112921_bib48","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1093\/nutrit\/nuv111","article-title":"Uric acid and transforming growth factor in fructose-induced production of reactive oxygen species in skeletal muscle","volume":"74","author":"Madlala","year":"2016","journal-title":"Nutr. Rev."},{"key":"10.1016\/j.mce.2026.112921_bib49","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1016\/j.foodres.2015.07.039","article-title":"Antioxidant potential of dietary chia seed and oil (Salvia hispanica L.) in diet-induced obese rats","volume":"76","author":"Marineli","year":"2015","journal-title":"Food Res. Int."},{"key":"10.1016\/j.mce.2026.112921_bib50","doi-asserted-by":"crossref","first-page":"740","DOI":"10.1016\/j.nut.2014.11.009","article-title":"Chia (Salvia hispanica L.) enhances HSP, PGC-1\u03b1 expressions and improves glucose tolerance in diet-induced obese rats","volume":"31","author":"Marineli","year":"2015","journal-title":"Nutrition"},{"key":"10.1016\/j.mce.2026.112921_bib51","doi-asserted-by":"crossref","DOI":"10.3390\/ijms24097898","article-title":"Mechanisms of oxidative stress in Metabolic syndrome","author":"Masenga","year":"2023","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.mce.2026.112921_bib52","author":"Matravadia"},{"key":"10.1016\/j.mce.2026.112921_bib53","doi-asserted-by":"crossref","DOI":"10.1016\/j.jff.2023.105480","article-title":"Health-promoting approaches of the use of chia seeds","author":"Motyka","year":"2023","journal-title":"J. Funct.Foods"},{"key":"10.1016\/j.mce.2026.112921_bib54","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0079356","article-title":"Conditional expression of TGF-\u03b21 in skeletal muscles causes endomysial fibrosis and myofibers atrophy","volume":"8","author":"Narola","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.mce.2026.112921_bib55","doi-asserted-by":"crossref","first-page":"259","DOI":"10.33549\/physiolres.930792","article-title":"Comparison of the phospholipid and triacylglycerol fatty acid profile of Rat Serum, skeletal muscle and heart","volume":"55","author":"Nikolaidis","year":"2006","journal-title":"Physiol. Res."},{"key":"10.1016\/j.mce.2026.112921_bib56","doi-asserted-by":"crossref","DOI":"10.1258\/002367707779399518","article-title":"Anthropometrical parameters and markers of obesity in rats","volume":"41","author":"Novelli","year":"2007","journal-title":"Lab. Anim."},{"key":"10.1016\/j.mce.2026.112921_bib57","article-title":"Metabolic adaptation in obesity and type ii diabetes: myokines, adipokines and hepatokines","volume":"18","author":"Oh","year":"2017","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.mce.2026.112921_bib58","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.bbrc.2022.05.033","article-title":"Quercetin attenuates adipogenesis and fibrosis in human skeletal muscle","volume":"615","author":"Ohmae","year":"2022","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.mce.2026.112921_bib59","doi-asserted-by":"crossref","first-page":"4851","DOI":"10.1039\/D5FO02156A","article-title":"Effects of astaxanthin on the mechanisms involved in skeletal muscle lipid metabolism and oxidative stress in an experimental model of metabolic syndrome","volume":"16","author":"Oliva","year":"2025","journal-title":"Food Funct."},{"key":"10.1016\/j.mce.2026.112921_bib60","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodres.2020.109842","article-title":"Salvia hispanica L. (chia) seed promotes body fat depletion and modulates adipocyte lipid handling in sucrose-rich diet-fed rats","volume":"139","author":"Oliva","year":"2021","journal-title":"Food Res. Int."},{"key":"10.1016\/j.mce.2026.112921_bib61","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/j.plefa.2013.09.010","article-title":"Dietary salba (salvia hispanica L) seed rich in \u03b1-linolenic acid improves adipose tissue dysfunction and the altered skeletal muscle glucose and lipid metabolism in dyslipidemic insulin-resistant rats","volume":"89","author":"Oliva","year":"2013","journal-title":"Prostaglandins Leukot. Essent. Fatty Acids"},{"key":"10.1016\/j.mce.2026.112921_bib62","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.jare.2023.04.005","article-title":"Potential nutritional strategies to prevent and reverse sarcopenia in aging process: role of fish oil-derived \u03c9-3 polyunsaturated fatty acids, wheat oligopeptide and their combined intervention","volume":"57","author":"Pan","year":"2024","journal-title":"J. Adv. Res."},{"key":"10.1016\/j.mce.2026.112921_bib63","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.cyto.2015.01.013","article-title":"The effects of high fat diet and moderate exercise on TGF\u03b21 and collagen deposition in mouse skeletal muscle","volume":"73","author":"Pincu","year":"2015","journal-title":"Cytokine"},{"key":"10.1016\/j.mce.2026.112921_bib64","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fphys.2015.00426","article-title":"Skeletal muscle mitochondrial bioenergetics and morphology in high fat diet induced obesity and insulin resistance: focus on dietary fat source","volume":"6","author":"Putti","year":"2016","journal-title":"Front. Physiol."},{"key":"10.1016\/j.mce.2026.112921_bib65","doi-asserted-by":"crossref","DOI":"10.1016\/j.orcp.2023.02.002","article-title":"Is obesity-induced ECM remodeling a prelude to the development of various diseases?","author":"Rahimi","year":"2023","journal-title":"Obes. Res. Clin. Pract."},{"key":"10.1016\/j.mce.2026.112921_bib66","article-title":"Effect of L-carnitine on skeletal muscle lipids and oxidative stress in rats fed high-fructose diet","volume":"2007","author":"Rajasekar","year":"2007","journal-title":"Exp. Diabesity Res."},{"key":"10.1016\/j.mce.2026.112921_bib67","doi-asserted-by":"crossref","first-page":"1939","DOI":"10.1093\/jn\/123.11.1939","article-title":"AIN-93 purified diets for laboratory rodents: final report of the American Institute of Nutrition Ad Hoc Writing Committee on the reformulation of the AIN-76A rodent diet","volume":"123","author":"Reeves","year":"1993","journal-title":"J. Nutr."},{"key":"10.1016\/j.mce.2026.112921_bib68","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2022.873699","article-title":"Adipokines, hepatokines and myokines: focus on their role and molecular mechanisms in adipose tissue inflammation","author":"Ren","year":"2022","journal-title":"Front. Endocrinol."},{"key":"10.1016\/j.mce.2026.112921_bib69","doi-asserted-by":"crossref","first-page":"10290","DOI":"10.1074\/jbc.M408985200","article-title":"Lipid infusion decreases the expression of nuclear encoded mitochondrial genes and increases the expression of extracellular matrix genes in human skeletal muscle","volume":"280","author":"Richardson","year":"2005","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.mce.2026.112921_bib70","author":"Richter-Stretton"},{"key":"10.1016\/j.mce.2026.112921_bib71","doi-asserted-by":"crossref","DOI":"10.1016\/j.lfs.2009.02.026","article-title":"Oxidative stress and metabolic syndrome","author":"Roberts","year":"2009","journal-title":"Life Sci."},{"key":"10.1016\/j.mce.2026.112921_bib72","doi-asserted-by":"crossref","first-page":"1617","DOI":"10.1017\/S0007114512003558","article-title":"Dietary chia seed induced changes in hepatic transcription factors and their target lipogenic and oxidative enzyme activities in dyslipidaemic insulin-resistant rats","volume":"109","author":"Rossi","year":"2013","journal-title":"Br. J. Nutr."},{"key":"10.1016\/j.mce.2026.112921_bib73","doi-asserted-by":"crossref","DOI":"10.1210\/endrev\/bnaa016","article-title":"Muscle\u2013organ crosstalk: the emerging roles of myokines","author":"Severinsen","year":"2020","journal-title":"Endocr. Rev."},{"key":"10.1016\/j.mce.2026.112921_bib74","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1016\/j.freeradbiomed.2018.10.422","article-title":"Attenuation of oxidative stress-induced lesions in skeletal muscle in a mouse model of obesity-independent hyperlipidaemia and atherosclerosis through the inhibition of Nox2 activity","volume":"129","author":"Sfyri","year":"2018","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.mce.2026.112921_bib75","doi-asserted-by":"crossref","DOI":"10.1038\/ncomms7693","article-title":"A muscle-liver-fat signalling axis is essential for central control of adaptive adipose remodelling","volume":"6","author":"Shimizu","year":"2015","journal-title":"Nat. Commun."},{"key":"10.1016\/j.mce.2026.112921_bib76","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/S0021-9150(00)00523-2","article-title":"Enhanced level of n-3 fatty acid in membrane phospholipids induces lipid peroxidation in rats fed dietary docosahexaenoic acid oil","volume":"155","author":"Song","year":"2001","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.mce.2026.112921_bib77","doi-asserted-by":"crossref","DOI":"10.1080\/07853890600888413","article-title":"The metabolic syndrome: role of skeletal muscle metabolism","author":"Stump","year":"2006","journal-title":"Ann. Med."},{"key":"10.1016\/j.mce.2026.112921_bib78","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.metabol.2016.10.009","article-title":"Skeletal muscle extracellular matrix remodeling after short-term overfeeding in healthy humans","volume":"67","author":"Tam","year":"2017","journal-title":"Metabolism"},{"key":"10.1016\/j.mce.2026.112921_bib79","doi-asserted-by":"crossref","DOI":"10.1089\/ars.2017.7342","article-title":"Transcriptional regulation by Nrf2. Antioxid","author":"Tonelli","year":"2018","journal-title":"Redox Signal"},{"key":"10.1016\/j.mce.2026.112921_bib80","article-title":"Astaxanthin obtained from freshwater crustaceans mitigates visceral adiposity by modulating adipose tissue lipogenesis and ameliorates dyslipidemia in high-sucrose diet fed rats","volume":"142","author":"Vargas","year":"2025","journal-title":"JNB (J. Nutr. Biochem.)"},{"key":"10.1016\/j.mce.2026.112921_bib81","doi-asserted-by":"crossref","first-page":"7333","DOI":"10.1039\/D2FO00642A","article-title":"Salvia hispanica L. (chia) seed ameliorates liver injury and oxidative stress by modulating NrF2 and NF\u03baB expression in sucrose-rich diet-fed rats","volume":"13","author":"Vega Joubert","year":"2022","journal-title":"Food Funct."},{"key":"10.1016\/j.mce.2026.112921_bib82","article-title":"Astaxanthin improves lipotoxicity, lipid peroxidation and oxidative stress in kidney of sucrose-rich diet-fed rats","volume":"135","author":"Vega Joubert","year":"2025","journal-title":"JNB (J. Nutr. Biochem.)"},{"key":"10.1016\/j.mce.2026.112921_bib83","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/j.jnutbio.2018.10.021","article-title":"Long-term follow-up of muscle lipid accumulation, mitochondrial activity and oxidative stress and their relationship with impaired glucose homeostasis in high fat high fructose diet-fed rats","volume":"64","author":"Wang","year":"2019","journal-title":"JNB (J. Nutr. Biochem.)"},{"key":"10.1016\/j.mce.2026.112921_bib84","doi-asserted-by":"crossref","DOI":"10.1152\/ajpcell.00154.2024","article-title":"Obesity and type 2 diabetes mellitus: insights from skeletal muscle extracellular matrix remodeling","author":"Wu","year":"2025","journal-title":"Am. J. Physiol. Cell Physiol."}],"container-title":["Molecular and Cellular Endocrinology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S030372072600198X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S030372072600198X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T15:41:57Z","timestamp":1791560517000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S030372072600198X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2027,2]]},"references-count":83,"alternative-id":["S030372072600198X"],"URL":"https:\/\/doi.org\/10.1016\/j.mce.2026.112921","relation":{},"ISSN":["0303-7207"],"issn-type":[{"value":"0303-7207","type":"print"}],"subject":[],"published":{"date-parts":[[2027,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Skeletal muscle redox imbalance and fibrosis in rats fed short- and long-term sucrose-rich diet: preventive effects of chia seed (Salvia hispanica L.)","name":"articletitle","label":"Article Title"},{"value":"Molecular and Cellular Endocrinology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.mce.2026.112921","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"112921"}}