{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T22:07:59Z","timestamp":1758924479321},"reference-count":48,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2004,2,1]],"date-time":"2004-02-01T00:00:00Z","timestamp":1075593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecular and Cellular Neuroscience"],"published-print":{"date-parts":[[2004,2]]},"DOI":"10.1016\/j.mcn.2003.10.017","type":"journal-article","created":{"date-parts":[[2003,12,30]],"date-time":"2003-12-30T12:05:34Z","timestamp":1072785934000},"page":"334-344","source":"Crossref","is-referenced-by-count":6,"title":["Ca 2+ -independent spine dynamics in cultured hippocampal neurons"],"prefix":"10.1016","volume":"25","author":[{"given":"Shengxiang","family":"Zhang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Timothy H.","family":"Murphy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.mcn.2003.10.017_BIB1","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1074\/jbc.273.2.805","article-title":"The small GTP-binding protein Rac promotes the dissociation of gelsolin from actin filaments in neutrophils","volume":"273","author":"Arcaro","year":"1998","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.mcn.2003.10.017_BIB2","doi-asserted-by":"crossref","first-page":"1362","DOI":"10.1093\/emboj\/17.5.1362","article-title":"Gelsolin is a downstream effector of rac for fibroblast motility","volume":"17","author":"Azuma","year":"1998","journal-title":"EMBO J."},{"key":"10.1016\/j.mcn.2003.10.017_BIB3","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1016\/S0896-6273(02)00906-6","article-title":"Spine motility. Phenomenology, mechanisms, and function","volume":"35","author":"Bonhoeffer","year":"2002","journal-title":"Neuron"},{"key":"10.1016\/j.mcn.2003.10.017_BIB4","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1016\/S0022-2836(02)01131-2","article-title":"The calcium activation of gelsolin: insights from the 3A structure of the G4-G6\/actin complex","volume":"324","author":"Choe","year":"2002","journal-title":"J. Mol. Biol."},{"key":"10.1016\/j.mcn.2003.10.017_BIB5","doi-asserted-by":"crossref","first-page":"1614","DOI":"10.1152\/jn.1997.77.3.1614","article-title":"Dendritic spine density and LTP induction in cultured hippocampal slices","volume":"77","author":"Collin","year":"1997","journal-title":"J. Neurophysiol."},{"key":"10.1016\/j.mcn.2003.10.017_BIB8","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/S0166-2236(03)00028-6","article-title":"Spine motility: a means towards an end?","volume":"26","author":"Dunaevsky","year":"2003","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.mcn.2003.10.017_BIB6","doi-asserted-by":"crossref","first-page":"13438","DOI":"10.1073\/pnas.96.23.13438","article-title":"Developmental regulation of spine motility in the mammalian central nervous system","volume":"96","author":"Dunaevsky","year":"1999","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.mcn.2003.10.017_BIB7","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1038\/89460","article-title":"Spine motility with synaptic contact","volume":"4","author":"Dunaevsky","year":"2001","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.mcn.2003.10.017_BIB9","doi-asserted-by":"crossref","first-page":"1387","DOI":"10.1016\/S0960-9822(00)00777-6","article-title":"The novel Rho-family GTPase rif regulates coordinated actin-based membrane rearrangements","volume":"10","author":"Ellis","year":"2000","journal-title":"Curr. Biol."},{"key":"10.1016\/j.mcn.2003.10.017_BIB10","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/S0896-6273(01)00190-8","article-title":"Calcium stores in hippocampal synaptic boutons mediate short-term plasticity, store-operated Ca2+ entry, and spontaneous transmitter release","volume":"29","author":"Emptage","year":"2001","journal-title":"Neuron"},{"key":"10.1016\/j.mcn.2003.10.017_BIB11","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1016\/S0896-6273(01)00440-8","article-title":"EphB\/syndecan-2 signaling in dendritic spine morphogenesis","volume":"31","author":"Ethell","year":"2001","journal-title":"Neuron"},{"key":"10.1016\/j.mcn.2003.10.017_BIB12","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1016\/S0896-6273(00)80467-5","article-title":"Rapid actin-based plasticity in dendritic spines","volume":"20","author":"Fischer","year":"1998","journal-title":"Neuron"},{"key":"10.1016\/j.mcn.2003.10.017_BIB13","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1038\/78791","article-title":"Glutamate receptors regulate actin-based plasticity in dendritic spines","volume":"3","author":"Fischer","year":"2000","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.mcn.2003.10.017_BIB14","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1038\/16927","article-title":"In vivo regulation of axon extension and pathfinding by growth-cone calcium transients","volume":"397","author":"Gomez","year":"1999","journal-title":"Nature"},{"key":"10.1016\/j.mcn.2003.10.017_BIB15","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1002\/1097-4695(200008)44:2<174::AID-NEU7>3.0.CO;2-R","article-title":"Regulation of growth cone behavior by calcium: new dynamics to earlier perspectives","volume":"44","author":"Gomez","year":"2000","journal-title":"J. Neurobiol."},{"key":"10.1016\/j.mcn.2003.10.017_BIB16","doi-asserted-by":"crossref","first-page":"1983","DOI":"10.1126\/science.1056490","article-title":"Filopodial calcium transients promote substrate-dependent growth cone turning","volume":"291","author":"Gomez","year":"2001","journal-title":"Science"},{"key":"10.1016\/j.mcn.2003.10.017_BIB17","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/S0896-6273(00)80785-0","article-title":"Destabilization of cortical dendrites and spines by BDNF","volume":"23","author":"Horch","year":"1999","journal-title":"Neuron"},{"key":"10.1016\/j.mcn.2003.10.017_BIB18","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1124\/mol.53.4.742","article-title":"Reverse Na+\/Ca2+ exchange contributes to glutamate-induced intracellular Ca2+ concentration increases in cultured rat forebrain neurons","volume":"53","author":"Hoyt","year":"1998","journal-title":"Mol. Pharmacol."},{"key":"10.1016\/j.mcn.2003.10.017_BIB19","doi-asserted-by":"crossref","first-page":"878","DOI":"10.1038\/13178","article-title":"Dendrites are more spiny on mature hippocampal neurons when synapses are inactivated","volume":"2","author":"Kirov","year":"1999","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.mcn.2003.10.017_BIB20","doi-asserted-by":"crossref","first-page":"6115","DOI":"10.1523\/JNEUROSCI.21-16-06115.2001","article-title":"Regulation of dendritic spine motility in cultured hippocampal neurons","volume":"21","author":"Korkotian","year":"2001","journal-title":"J. Neurosci."},{"key":"10.1016\/j.mcn.2003.10.017_BIB21","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1016\/S0896-6273(01)00314-2","article-title":"Spike-associated fast contraction of dendritic spines in cultured hippocampal neurons","volume":"30","author":"Korkotian","year":"2001","journal-title":"Neuron"},{"key":"10.1016\/j.mcn.2003.10.017_BIB22","doi-asserted-by":"crossref","first-page":"876","DOI":"10.1038\/35009107","article-title":"Experience-dependent plasticity of dendritic spines in the developing rat barrel cortex in vivo","volume":"404","author":"Lendvai","year":"2000","journal-title":"Nature"},{"key":"10.1016\/j.mcn.2003.10.017_BIB23","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1038\/nature00850","article-title":"Transmitter-evoked local calcium release stabilizes developing dendrites","volume":"418","author":"Lohmann","year":"2002","journal-title":"Nature"},{"key":"10.1016\/j.mcn.2003.10.017_BIB24","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1016\/S0896-6273(00)80098-7","article-title":"Ca2+ imaging of CNS axons in culture indicates reliable coupling between single action potentials and distal functional release sites","volume":"16","author":"Mackenzie","year":"1996","journal-title":"Neuron"},{"key":"10.1016\/j.mcn.2003.10.017_BIB25","doi-asserted-by":"crossref","first-page":"1923","DOI":"10.1126\/science.283.5409.1923","article-title":"Rapid dendritic morphogenesis in CA1 hippocampal dendrites induced by synaptic activity","volume":"283","author":"Maletic-Savatic","year":"1999","journal-title":"Science"},{"key":"10.1016\/j.mcn.2003.10.017_BIB26","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1046\/j.1471-4159.2002.01185.x","article-title":"Signaling mechanisms that regulate actin-based motility processes in the nervous system","volume":"83","author":"Meyer","year":"2002","journal-title":"J. Neurochem."},{"key":"10.1016\/j.mcn.2003.10.017_BIB27","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1016\/S0896-6273(02)01020-6","article-title":"Roles of neurotransmitter in synapse formation: development of neuromuscular junctions lacking choline acetyltransferase","volume":"36","author":"Misgeld","year":"2002","journal-title":"Neuron"},{"key":"10.1016\/j.mcn.2003.10.017_BIB28","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1126\/science.7904774","article-title":"Visualization of quantal synaptic transmission by dendritic calcium imaging","volume":"263","author":"Murphy","year":"1994","journal-title":"Science"},{"key":"10.1016\/j.mcn.2003.10.017_BIB29","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1007\/BF03160356","article-title":"Phosphoinositide turnover and calcium ion mobilization in receptor activation","volume":"9","author":"Nozawa","year":"1988","journal-title":"Neurochem. Pathol."},{"key":"10.1016\/j.mcn.2003.10.017_BIB30","doi-asserted-by":"crossref","first-page":"9920","DOI":"10.1074\/jbc.M208872200","article-title":"RICS, a novel GTPase-activating protein for Cdc42 and Rac1, is involved in the beta-catenin-N-cadherin and N-methyl-d-aspartate receptor signaling","volume":"278","author":"Okabe","year":"2003","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.mcn.2003.10.017_BIB31","series-title":"Handbook of Biological Confocal Microscopy","author":"Pawley","year":"1995"},{"key":"10.1016\/j.mcn.2003.10.017_BIB32","doi-asserted-by":"crossref","first-page":"7129","DOI":"10.1523\/JNEUROSCI.23-18-07129.2003","article-title":"Activity-regulated dynamic behavior of early dendritic protrusions: evidence for different types of dendritic filopodia","volume":"23","author":"Portera-Cailliau","year":"2003","journal-title":"J. Neurosci."},{"key":"10.1016\/j.mcn.2003.10.017_BIB33","doi-asserted-by":"crossref","first-page":"9325","DOI":"10.1523\/JNEUROSCI.21-23-09325.2001","article-title":"Modular transport of postsynaptic density-95 clusters and association with stable spine precursors during early development of cortical neurons","volume":"21","author":"Prange","year":"2001","journal-title":"J. Neurosci."},{"key":"10.1016\/j.mcn.2003.10.017_BIB34","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/S0165-3806(00)00148-6","article-title":"The role of calcium signaling in early axonal and dendritic morphogenesis of rat cerebral cortex neurons under non-stimulated growth conditions","volume":"126","author":"Ramakers","year":"2001","journal-title":"Brain Res. Dev. Brain Res."},{"key":"10.1016\/j.mcn.2003.10.017_BIB35","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1002\/1098-1063(2000)10:5<527::AID-HIPO3>3.0.CO;2-B","article-title":"Signaling between the actin cytoskeleton and the postsynaptic density of dendritic spines","volume":"10","author":"Rao","year":"2000","journal-title":"Hippocampus"},{"key":"10.1016\/j.mcn.2003.10.017_BIB36","doi-asserted-by":"crossref","first-page":"3550","DOI":"10.1073\/pnas.97.7.3550","article-title":"Colocalization of integrin receptors and reelin in dendritic spine postsynaptic densities of adult nonhuman primate cortex","volume":"97","author":"Rodriguez","year":"2000","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.mcn.2003.10.017_BIB37","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1038\/nature00987","article-title":"Dendrite growth increased by visual activity requires NMDA receptor and Rho GTPases","volume":"419","author":"Sin","year":"2002","journal-title":"Nature"},{"key":"10.1016\/j.mcn.2003.10.017_BIB38","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1038\/nn811","article-title":"Rapid turnover of actin in dendritic spines and its regulation by activity","volume":"5","author":"Star","year":"2002","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.mcn.2003.10.017_BIB39","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1016\/0165-3806(93)90217-X","article-title":"Gelsolin is localized in neuronal growth cones","volume":"76","author":"Tanaka","year":"1993","journal-title":"Brain Res. Dev. Brain Res."},{"key":"10.1016\/j.mcn.2003.10.017_BIB40","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1038\/nature01273","article-title":"Long-term in vivo imaging of experience-dependent synaptic plasticity in adult cortex","volume":"420","author":"Trachtenberg","year":"2002","journal-title":"Nature"},{"key":"10.1016\/j.mcn.2003.10.017_BIB41","doi-asserted-by":"crossref","first-page":"9037","DOI":"10.1073\/pnas.122623799","article-title":"Total arrest of spontaneous and evoked synaptic transmission but normal synaptogenesis in the absence of Munc13-mediated vesicle priming","volume":"99","author":"Varoqueaux","year":"2002","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.mcn.2003.10.017_BIB42","doi-asserted-by":"crossref","first-page":"864","DOI":"10.1126\/science.287.5454.864","article-title":"Synaptic assembly of the brain in the absence of neurotransmitter secretion","volume":"287","author":"Verhage","year":"2000","journal-title":"Science"},{"key":"10.1016\/j.mcn.2003.10.017_BIB43","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1038\/nn783","article-title":"Genetic ablation of the t-SNARE SNAP-25 distinguishes mechanisms of neuroexocytosis","volume":"5","author":"Washbourne","year":"2002","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.mcn.2003.10.017_BIB44","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1038\/85987","article-title":"Changing specificity of neurotransmitter regulation of rapid dendritic remodeling during synaptogenesis","volume":"4","author":"Wong","year":"2001","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.mcn.2003.10.017_BIB45","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1002\/neu.480220704","article-title":"Remodeling of retinal ganglion cell dendrites in the absence of action potential activity","volume":"22","author":"Wong","year":"1991","journal-title":"J. Neurobiol."},{"key":"10.1016\/j.mcn.2003.10.017_BIB46","doi-asserted-by":"crossref","first-page":"1207","DOI":"10.1038\/nn753","article-title":"Electrical activity and development of neural circuits","volume":"4","author":"Zhang","year":"2001","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.mcn.2003.10.017_BIB47","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1002\/(SICI)1096-9861(20000522)421:1<95::AID-CNE6>3.0.CO;2-5","article-title":"Developmental changes in metabotropic glutamate receptor-mediated calcium homeostasis","volume":"421","author":"Zirpel","year":"2000","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.mcn.2003.10.017_BIB48","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/S0896-6273(00)80283-4","article-title":"Evidence for a role of dendritic filopodia in synaptogenesis and spine formation","volume":"17","author":"Ziv","year":"1996","journal-title":"Neuron"}],"container-title":["Molecular and Cellular Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1044743103003397?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1044743103003397?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,4,27]],"date-time":"2023-04-27T17:38:31Z","timestamp":1682617111000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1044743103003397"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,2]]},"references-count":48,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2004,2]]}},"alternative-id":["S1044743103003397"],"URL":"https:\/\/doi.org\/10.1016\/j.mcn.2003.10.017","relation":{},"ISSN":["1044-7431"],"issn-type":[{"value":"1044-7431","type":"print"}],"subject":[],"published":{"date-parts":[[2004,2]]}}}