{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T07:05:07Z","timestamp":1790665507698,"version":"4.1.0"},"reference-count":45,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100014370","name":"Simons Foundation Autism Research Initiative","doi-asserted-by":"crossref","award":["SFARI-177037"],"award-info":[{"award-number":["SFARI-177037"]}],"id":[{"id":"10.13039\/100014370","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["NS050356"],"award-info":[{"award-number":["NS050356"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Zachry Foundation"},{"name":"University of Texas Health Science Center, San Antonio"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Molecular and Cellular Neuroscience"],"published-print":{"date-parts":[[2017,1]]},"DOI":"10.1016\/j.mcn.2016.11.004","type":"journal-article","created":{"date-parts":[[2016,11,10]],"date-time":"2016-11-10T00:47:48Z","timestamp":1478738868000},"page":"9-24","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":35,"special_numbering":"C","title":["Neurexin, Neuroligin and Wishful Thinking coordinate synaptic cytoarchitecture and growth at neuromuscular junctions"],"prefix":"10.1016","volume":"78","author":[{"given":"Swati","family":"Banerjee","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anandakrishnan","family":"Venkatesan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manzoor A.","family":"Bhat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.mcn.2016.11.004_bb0005","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1016\/S0896-6273(02)00589-5","article-title":"Wishful thinking encodes a BMP type II receptor that regulates synaptic growth in Drosophila","volume":"33","author":"Aberle","year":"2002","journal-title":"Neuron"},{"key":"10.1016\/j.mcn.2016.11.004_bb0010","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1038\/nn.4037","article-title":"Distinct circuit-dependent functions of presynaptic neurexin-3 at GABAergic and glutamatergic synapses","volume":"18","author":"Aoto","year":"2015","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.mcn.2016.11.004_bb0015","doi-asserted-by":"crossref","first-page":"5943","DOI":"10.1523\/JNEUROSCI.1144-05.2005","article-title":"Fasciclin II signals new synapse formation through amyloid precursor protein and scaffolding protein dX11\/Mint","volume":"25","author":"Ashley","year":"2005","journal-title":"J. Neurosci."},{"key":"10.1016\/j.mcn.2016.11.004_bb0020","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1016\/j.neuron.2010.04.011","article-title":"Retrograde BMP signaling controls synaptic growth at the NMJ by regulating trio expression in motor neurons","volume":"66","author":"Ball","year":"2010","journal-title":"Neuron"},{"key":"10.1016\/j.mcn.2016.11.004_bb0025","doi-asserted-by":"crossref","first-page":"3319","DOI":"10.1523\/JNEUROSCI.5383-05.2006","article-title":"Axonal ensheathment and septate junction formation in the peripheral nervous system of Drosophila","volume":"26","author":"Banerjee","year":"2006","journal-title":"J. Neurosci. Off. J. Soc. Neurosci."},{"key":"10.1016\/j.mcn.2016.11.004_bb0030","doi-asserted-by":"crossref","first-page":"58","DOI":"10.3389\/fncel.2014.00058","article-title":"Genetic aspects of autism spectrum disorders: insights from animal models","volume":"8","author":"Banerjee","year":"2014","journal-title":"Front. Cell. Neurosci."},{"key":"10.1016\/j.mcn.2016.11.004_bb0035","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1016\/j.neuron.2010.05.020","article-title":"Drosophila neuroligin 1 promotes growth and postsynaptic differentiation at glutamatergic neuromuscular junctions","volume":"66","author":"Banovic","year":"2010","journal-title":"Neuron"},{"key":"10.1016\/j.mcn.2016.11.004_bb0040","doi-asserted-by":"crossref","first-page":"17937","DOI":"10.1523\/JNEUROSCI.6075-11.2013","article-title":"Retrograde BMP signaling at the synapse: a permissive signal for synapse maturation and activity-dependent plasticity","volume":"33","author":"Berke","year":"2013","journal-title":"J. Neurosci."},{"key":"10.1016\/j.mcn.2016.11.004_bb0045","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1016\/S0896-6273(00)80196-8","article-title":"Regulation of synapse structure and function by the Drosophila tumor suppressor gene dlg","volume":"17","author":"Budnik","year":"1996","journal-title":"Neuron"},{"key":"10.1016\/j.mcn.2016.11.004_bb0050","doi-asserted-by":"crossref","first-page":"10773","DOI":"10.1038\/ncomms10773","article-title":"Mapping the dynamics and nanoscale organization of synaptic adhesion proteins using monomeric streptavidin","volume":"7","author":"Chamma","year":"2016","journal-title":"Nat. Commun."},{"key":"10.1016\/j.mcn.2016.11.004_bb0055","doi-asserted-by":"crossref","first-page":"16018","DOI":"10.1523\/JNEUROSCI.1685-12.2012","article-title":"Drosophila neuroligin 2 is required presynaptically and postsynaptically for proper synaptic differentiation and synaptic transmission","volume":"32","author":"Chen","year":"2012","journal-title":"J. Neurosci. Off. J. Soc. Neurosci."},{"key":"10.1016\/j.mcn.2016.11.004_bb0060","doi-asserted-by":"crossref","first-page":"1324","DOI":"10.1126\/science.1107470","article-title":"Control of excitatory and inhibitory synapse formation by neuroligins","volume":"307","author":"Chih","year":"2005","journal-title":"Science"},{"key":"10.1016\/j.mcn.2016.11.004_bb0065","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1016\/j.neuron.2007.05.029","article-title":"Activity-dependent validation of excitatory versus inhibitory synapses by neuroligin-1 versus neuroligin-2","volume":"54","author":"Chubykin","year":"2007","journal-title":"Neuron"},{"key":"10.1016\/j.mcn.2016.11.004_bb0070","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1016\/j.cub.2006.02.061","article-title":"Postsynaptic mad signaling at the Drosophila neuromuscular junction","volume":"16","author":"Dudu","year":"2006","journal-title":"Curr. Biol."},{"key":"10.1016\/j.mcn.2016.11.004_bb0075","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1016\/S0896-6273(02)00721-3","article-title":"Dynactin is necessary for synapse stabilization","volume":"34","author":"Eaton","year":"2002","journal-title":"Neuron"},{"key":"10.1016\/j.mcn.2016.11.004_bb0080","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1016\/j.cell.2004.11.035","article-title":"Neurexins induce differentiation of GABA and glutamate postsynaptic specializations via neuroligins","volume":"119","author":"Graf","year":"2004","journal-title":"Cell"},{"key":"10.1016\/j.mcn.2016.11.004_bb0085","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1016\/0092-8674(95)90396-8","article-title":"Neuroligin 1: a splice site-specific ligand for beta-neurexins","volume":"81","author":"Ichtchenko","year":"1995","journal-title":"Cell"},{"key":"10.1016\/j.mcn.2016.11.004_bb0090","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1016\/0896-6273(94)90249-6","article-title":"The Drosophila tumor suppressor gene dlg is required for normal synaptic bouton structure","volume":"13","author":"Lahey","year":"1994","journal-title":"Neuron"},{"key":"10.1016\/j.mcn.2016.11.004_bb0095","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1016\/j.neuron.2007.08.002","article-title":"Crucial role of Drosophila neurexin in proper active zone apposition to postsynaptic densities, synaptic growth, and synaptic transmission","volume":"55","author":"Li","year":"2007","journal-title":"Neuron"},{"key":"10.1016\/j.mcn.2016.11.004_bb2000","doi-asserted-by":"crossref","first-page":"15545","DOI":"10.1523\/JNEUROSCI.0819-13.2013","article-title":"Drosophila Neuroligin 4 regulates sleep through modulating GABA transmission","volume":"33","author":"Li","year":"2013","journal-title":"J. Neurosci."},{"key":"10.1016\/j.mcn.2016.11.004_bb0100","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1016\/S0896-6273(02)00595-0","article-title":"The Drosophila BMP type II receptor wishful thinking regulates neuromuscular synapse morphology and function","volume":"33","author":"Marques","year":"2002","journal-title":"Neuron"},{"key":"10.1016\/j.mcn.2016.11.004_bb0105","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/S0896-6273(03)00426-4","article-title":"The BMP homolog Gbb provides a retrograde signal that regulates synaptic growth at the Drosophila neuromuscular junction","volume":"39","author":"McCabe","year":"2003","journal-title":"Neuron"},{"key":"10.1016\/j.mcn.2016.11.004_bb0110","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1083\/jcb.200809127","article-title":"Nemo kinase interacts with Mad to coordinate synaptic growth at the Drosophila neuromuscular junction","volume":"185","author":"Merino","year":"2009","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.mcn.2016.11.004_bb0115","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1038\/nature01755","article-title":"Alpha-neurexins couple Ca2+ channels to synaptic vesicle exocytosis","volume":"423","author":"Missler","year":"2003","journal-title":"Nature"},{"key":"10.1016\/j.mcn.2016.11.004_bb0120","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.mcn.2012.08.010","article-title":"Drosophila neuroligin 1 regulates synaptic growth and function in response to activity and phosphoinositide-3-kinase","volume":"51","author":"Mozer","year":"2012","journal-title":"Mol. Cell. Neurosci."},{"key":"10.1016\/j.mcn.2016.11.004_bb0125","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1016\/j.neuron.2012.12.015","article-title":"Spartin regulates synaptic growth and neuronal survival by inhibiting BMP-mediated microtubule stabilization","volume":"77","author":"Nahm","year":"2013","journal-title":"Neuron"},{"key":"10.1016\/j.mcn.2016.11.004_bb0130","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/S0925-4773(01)00503-2","article-title":"BMP growth factors and Phox2 transcription factors can induce synaptotagmin I and neurexin I during sympathetic neuron development","volume":"108","author":"Patzke","year":"2001","journal-title":"Mech. Dev."},{"key":"10.1016\/j.mcn.2016.11.004_bb0135","doi-asserted-by":"crossref","first-page":"918","DOI":"10.1016\/j.cub.2005.04.030","article-title":"Presynaptic spectrin is essential for synapse stabilization","volume":"15","author":"Pielage","year":"2005","journal-title":"Curr. Biol."},{"key":"10.1016\/j.mcn.2016.11.004_bb0140","doi-asserted-by":"crossref","first-page":"13915","DOI":"10.1073\/pnas.0405939101","article-title":"A balance between excitatory and inhibitory synapses is controlled by PSD-95 and neuroligin","volume":"101","author":"Prange","year":"2004","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.mcn.2016.11.004_bb0145","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1002\/neu.10189","article-title":"Drosophila neuromuscular synapse assembly and function require the TGF-beta type I receptor saxophone and the transcription factor Mad","volume":"55","author":"Rawson","year":"2003","journal-title":"J. Neurobiol."},{"key":"10.1016\/j.mcn.2016.11.004_bb0150","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1016\/j.cell.2014.04.045","article-title":"Autism-associated neuroligin-3 mutations commonly impair striatal circuits to boost repetitive behaviors","volume":"158","author":"Rothwell","year":"2014","journal-title":"Cell"},{"key":"10.1016\/j.mcn.2016.11.004_bb0155","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1016\/S0092-8674(00)80877-6","article-title":"Neuroligin expressed in nonneuronal cells triggers presynaptic development in contacting axons","volume":"101","author":"Scheiffele","year":"2000","journal-title":"Cell"},{"key":"10.1016\/j.mcn.2016.11.004_bb0160","doi-asserted-by":"crossref","first-page":"11267","DOI":"10.1523\/JNEUROSCI.2722-06.2006","article-title":"Non-NMDA-type glutamate receptors are essential for maturation but not for initial assembly at Drosophila neuromuscular junctions","volume":"26","author":"Schmid","year":"2006","journal-title":"J. Neurosci."},{"key":"10.1016\/j.mcn.2016.11.004_bb0165","doi-asserted-by":"crossref","first-page":"1100","DOI":"10.1073\/pnas.96.3.1100","article-title":"Neuroligin 1 is a postsynaptic cell-adhesion molecule of excitatory synapses","volume":"96","author":"Song","year":"1999","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.mcn.2016.11.004_bb0170","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1038\/nature07456","article-title":"Neuroligins and neurexins link synaptic function to cognitive disease","volume":"455","author":"Sudhof","year":"2008","journal-title":"Nature"},{"issue":"1","key":"10.1016\/j.mcn.2016.11.004_bb2005","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1005810","article-title":"A novel, noncanonical BMP pathway modulates synapse maturation at the Drosophila neuromuscular junction","volume":"12","author":"Sulkowski","year":"2016","journal-title":"PLoS Genet."},{"key":"10.1016\/j.mcn.2016.11.004_bb0175","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1242\/dev.097758","article-title":"Postsynaptic glutamate receptors regulate local BMP signaling at the Drosophila neuromuscular junction","volume":"141","author":"Sulkowski","year":"2014","journal-title":"Development"},{"key":"10.1016\/j.mcn.2016.11.004_bb0180","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1016\/S0896-6273(00)80961-7","article-title":"Synaptic clustering of the cell adhesion molecule fasciclin II by discs-large and its role in the regulation of presynaptic structure","volume":"19","author":"Thomas","year":"1997","journal-title":"Neuron"},{"key":"10.1016\/j.mcn.2016.11.004_bb0185","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/j.neuron.2012.11.012","article-title":"Neurexin regulates visual function via mediating retinoid transport to promote rhodopsin maturation","volume":"77","author":"Tian","year":"2013","journal-title":"Neuron"},{"key":"10.1016\/j.mcn.2016.11.004_bb0190","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1126\/science.1621094","article-title":"Neurexins: synaptic cell surface proteins related to the alpha-latrotoxin receptor and laminin","volume":"257","author":"Ushkaryov","year":"1992","journal-title":"Science"},{"key":"10.1016\/j.mcn.2016.11.004_bb0195","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1016\/j.neuron.2006.09.003","article-title":"Neuroligins determine synapse maturation and function","volume":"51","author":"Varoqueaux","year":"2006","journal-title":"Neuron"},{"key":"10.1016\/j.mcn.2016.11.004_bb0200","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1016\/j.neuron.2006.02.008","article-title":"Bruchpilot, a protein with homology to ELKS\/CAST, is required for structural integrity and function of synaptic active zones in Drosophila","volume":"49","author":"Wagh","year":"2006","journal-title":"Neuron"},{"key":"10.1016\/j.mcn.2016.11.004_bb0205","doi-asserted-by":"crossref","first-page":"13564","DOI":"10.1073\/pnas.0905819106","article-title":"Postsynaptic Neuroligin1 regulates presynaptic maturation","volume":"106","author":"Wittenmayer","year":"2009","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.mcn.2016.11.004_bb0210","doi-asserted-by":"crossref","first-page":"31867","DOI":"10.1074\/jbc.M114.574897","article-title":"Drosophila neuroligin 3 regulates neuromuscular junction development and synaptic differentiation. J","volume":"289","author":"Xing","year":"2014","journal-title":"Biol. Chem."},{"key":"10.1016\/j.mcn.2016.11.004_bb0215","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1016\/j.neuron.2015.07.020","article-title":"Neuroligins sculpt cerebellar Purkinje-cell circuits by differential control of distinct classes of synapses","volume":"87","author":"Zhang","year":"2015","journal-title":"Neuron"}],"container-title":["Molecular and Cellular Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1044743116302354?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1044743116302354?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,5,17]],"date-time":"2020-05-17T05:14:06Z","timestamp":1589692446000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1044743116302354"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,1]]},"references-count":45,"alternative-id":["S1044743116302354"],"URL":"https:\/\/doi.org\/10.1016\/j.mcn.2016.11.004","relation":{},"ISSN":["1044-7431"],"issn-type":[{"value":"1044-7431","type":"print"}],"subject":[],"published":{"date-parts":[[2017,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Neurexin, Neuroligin and Wishful Thinking coordinate synaptic cytoarchitecture and growth at neuromuscular junctions","name":"articletitle","label":"Article Title"},{"value":"Molecular and Cellular Neuroscience","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.mcn.2016.11.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}