{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T03:54:40Z","timestamp":1791431680841,"version":"4.3.3"},"reference-count":189,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,12,1]],"date-time":"2019-12-01T00:00:00Z","timestamp":1575158400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,12,1]],"date-time":"2019-12-01T00:00:00Z","timestamp":1575158400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001839","name":"University Grants Committee","doi-asserted-by":"publisher","award":["247"],"award-info":[{"award-number":["247"]}],"id":[{"id":"10.13039\/501100001839","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001407","name":"Department of Biotechnology, Ministry of Science and Technology, India","doi-asserted-by":"publisher","award":["BT\/PR16164\/NER\/95\/88\/2015"],"award-info":[{"award-number":["BT\/PR16164\/NER\/95\/88\/2015"]}],"id":[{"id":"10.13039\/501100001407","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001407","name":"Department of Biotechnology, Ministry of Science and Technology, India","doi-asserted-by":"publisher","award":["PAC-JNU-DST-PURSE-462"],"award-info":[{"award-number":["PAC-JNU-DST-PURSE-462"]}],"id":[{"id":"10.13039\/501100001407","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006755","name":"School of Life Sciences, Arizona State University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006755","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Molecular and Cellular Neuroscience"],"published-print":{"date-parts":[[2019,12]]},"DOI":"10.1016\/j.mcn.2019.103414","type":"journal-article","created":{"date-parts":[[2019,10,23]],"date-time":"2019-10-23T12:52:52Z","timestamp":1571835172000},"page":"103414","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":49,"special_numbering":"C","title":["Role of GPCR signaling and calcium dysregulation in Alzheimer's disease"],"prefix":"10.1016","volume":"101","author":[{"family":"Sushma","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amal Chandra","family":"Mondal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"7","key":"10.1016\/j.mcn.2019.103414_bb0005","doi-asserted-by":"crossref","first-page":"992","DOI":"10.1016\/j.neurobiolaging.2007.01.003","article-title":"A\u03b21\u201342 modulation of Akt phosphorylation via \u03b17 nAChR and NMDA receptors","volume":"29","author":"Abbott","year":"2008","journal-title":"Neurobiol. Aging"},{"issue":"12","key":"10.1016\/j.mcn.2019.103414_bb0010","doi-asserted-by":"crossref","first-page":"1584","DOI":"10.1016\/j.bbadis.2011.08.013","article-title":"Calcium channel blocking as a therapeutic strategy for Alzheimer's disease: the case for isradipine","volume":"1812","author":"Anekonda","year":"2011","journal-title":"Biochimica Et Biophysica Acta (BBA)-Molecular Basis of Disease"},{"issue":"1","key":"10.1016\/j.mcn.2019.103414_bb0015","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.nbd.2010.08.020","article-title":"L-type voltage-gated calcium channel blockade with isradipine as a therapeutic strategy for Alzheimer\u2019s disease","volume":"41","author":"Anekonda","year":"2011","journal-title":"Neurobiol. Dis."},{"issue":"1","key":"10.1016\/j.mcn.2019.103414_bb0020","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.neurobiolaging.2014.08.004","article-title":"Deregulation of purine metabolism in Alzheimer\u2019s disease","volume":"36","author":"Ansoleaga","year":"2015","journal-title":"Neurobiol. Aging"},{"issue":"4","key":"10.1016\/j.mcn.2019.103414_bb0025","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1016\/j.neuroscience.2006.07.021","article-title":"Caffeine protects Alzheimer\u2019s mice against cognitive impairment and reduces brain beta-amyloid production","volume":"142","author":"Arendash","year":"2006","journal-title":"Neuroscience"},{"issue":"3","key":"10.1016\/j.mcn.2019.103414_bb0030","doi-asserted-by":"crossref","first-page":"661","DOI":"10.3233\/JAD-2009-1087","article-title":"Caffeine reverses cognitive impairment and decreases brain amyloid-beta levels in aged Alzheimer\u2019s disease mice","volume":"17","author":"Arendash","year":"2009","journal-title":"J. Alzheimers Dis."},{"issue":"3","key":"10.1016\/j.mcn.2019.103414_bb0035","first-page":"367","article-title":"Alzheimer\u2019s disease facts and figures","volume":"14","author":"Association, A.s","year":"2018","journal-title":"Alzheimers Dement."},{"key":"10.1016\/j.mcn.2019.103414_bb0040","doi-asserted-by":"crossref","unstructured":"Bading, H., Therapeutic targeting of the pathological triad of extrasynaptic NMDA receptor signaling in neurodegenerations. J. Exp. Med.. 214(3): p. 569-578.","DOI":"10.1084\/jem.20161673"},{"issue":"4","key":"10.1016\/j.mcn.2019.103414_bb0045","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1016\/j.cell.2005.02.001","article-title":"Mitochondria, oxidants, and aging","volume":"120","author":"Balaban","year":"2005","journal-title":"cell"},{"key":"10.1016\/j.mcn.2019.103414_bb0050","series-title":"Protein Trafficking in Neurons","first-page":"203","article-title":"Subunit-specific NMDA receptor trafficking to synapses","author":"Barria","year":"2007"},{"issue":"31","key":"10.1016\/j.mcn.2019.103414_bb0055","doi-asserted-by":"crossref","first-page":"20796","DOI":"10.1074\/jbc.M109.025353","article-title":"Calcium elevation in mitochondria is the main Ca2+ requirement for mitochondrial permeability transition pore (mPTP) opening","volume":"284","author":"Baumgartner","year":"2009","journal-title":"J. Biol. Chem."},{"issue":"7","key":"10.1016\/j.mcn.2019.103414_bb0060","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1038\/nrm1155","article-title":"Calcium: calcium signalling: dynamics, homeostasis and remodelling","volume":"4","author":"Berridge","year":"2003","journal-title":"Nat. Rev. Mol. Cell Biol."},{"issue":"3","key":"10.1016\/j.mcn.2019.103414_bb0065","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.molmed.2009.01.001","article-title":"Calcium signaling and neurodegenerative diseases","volume":"15","author":"Bezprozvanny","year":"2009","journal-title":"Trends Mol. Med."},{"issue":"1","key":"10.1016\/j.mcn.2019.103414_bb0070","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1186\/1750-1326-8-23","article-title":"The synaptic maintenance problem: membrane recycling, Ca 2+ homeostasis and late onset degeneration","volume":"8","author":"Bezprozvanny","year":"2013","journal-title":"Mol. Neurodegener."},{"key":"10.1016\/j.mcn.2019.103414_bb0075","doi-asserted-by":"crossref","DOI":"10.1002\/14651858.CD001191.pub3","article-title":"Rivastigmine for Alzheimer\u2019s disease","volume":"4","author":"Birks","year":"2015","journal-title":"Cochrane Database Syst. Rev."},{"issue":"1\u20134","key":"10.1016\/j.mcn.2019.103414_bb0080","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1159\/000149798","article-title":"Memantine potentiates agonist-induced Ca2+ responses in HEK 293 cells","volume":"22","author":"Blanchard","year":"2008","journal-title":"Cell. Physiol. Biochem."},{"issue":"243","key":"10.1016\/j.mcn.2019.103414_bb0085","first-page":"pe34","article-title":"Store-operated channels: diversity and activation mechanisms","volume":"2004","author":"Bolotina","year":"2004","journal-title":"Sci. Signal."},{"key":"10.1016\/j.mcn.2019.103414_bb0090","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1100\/tsw.2001.489","article-title":"Extracellular and intracellular regulation of calcium homeostasis","volume":"1","author":"Bronner","year":"2001","journal-title":"Sci. World J."},{"issue":"4","key":"10.1016\/j.mcn.2019.103414_bb0095","first-page":"C817","article-title":"Calcium, ATP, and ROS: a mitochondrial love-hate triangle","volume":"287","author":"Brookes","year":"2004","journal-title":"Am. J. Phys. Cell Phys."},{"issue":"3","key":"10.1016\/j.mcn.2019.103414_bb0100","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1016\/j.jalz.2007.04.381","article-title":"Forecasting the global burden of Alzheimer\u2019s disease","volume":"3","author":"Brookmeyer","year":"2007","journal-title":"Alzheimers Dement."},{"issue":"1","key":"10.1016\/j.mcn.2019.103414_bb0105","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1097\/01.wad.0000201847.29836.a5","article-title":"Efficacy and safety of memantine in moderate-to-severe Alzheimer disease: the evidence to date","volume":"20","author":"Bullock","year":"2006","journal-title":"Alzheimer Dis. Assoc. Disord."},{"issue":"7","key":"10.1016\/j.mcn.2019.103414_bb0110","doi-asserted-by":"crossref","first-page":"1530","DOI":"10.1016\/j.bbamem.2012.08.028","article-title":"Structure and function of the \u03b2 subunit of voltage-gated Ca2+ channels","volume":"1828","author":"Buraei","year":"2013","journal-title":"Biochimica et Biophysica Acta (BBA)-Biomembranes"},{"key":"10.1016\/j.mcn.2019.103414_bb0115","doi-asserted-by":"crossref","first-page":"a035154","DOI":"10.1101\/cshperspect.a035154","article-title":"Calcium sensors in neuronal function and dysfunction","author":"Burgoyne","year":"2019","journal-title":"Cold Spring Harb. Perspect. Biol."},{"issue":"2","key":"10.1016\/j.mcn.2019.103414_bb0120","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/j.pneurobio.2011.08.006","article-title":"Purinergic signalling: from normal behaviour to pathological brain function","volume":"95","author":"Burnstock","year":"2011","journal-title":"Prog. Neurobiol."},{"issue":"24","key":"10.1016\/j.mcn.2019.103414_bb0125","doi-asserted-by":"crossref","first-page":"10153","DOI":"10.1074\/jbc.M116.743070","article-title":"Amyloid \u03b2 production is regulated by \u03b22-adrenergic signaling-mediated post-translational modifications of the ryanodine receptor","volume":"292","author":"Bussiere","year":"2017","journal-title":"J. Biol. Chem."},{"issue":"3","key":"10.1016\/j.mcn.2019.103414_bb0130","first-page":"303","article-title":"Donepezil in Alzheimer\u2019s disease: from conventional trials to pharmacogenetics","volume":"3","author":"Cacabelos","year":"2007","journal-title":"Neuropsychiatr. Dis. Treat."},{"issue":"5","key":"10.1016\/j.mcn.2019.103414_bb0135","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1016\/j.neuron.2006.01.020","article-title":"M1 receptors play a central role in modulating AD-like pathology in transgenic mice","volume":"49","author":"Caccamo","year":"2006","journal-title":"Neuron"},{"issue":"37","key":"10.1016\/j.mcn.2019.103414_bb0140","doi-asserted-by":"crossref","first-page":"13272","DOI":"10.1523\/JNEUROSCI.3337-11.2011","article-title":"Adenosine receptor signaling modulates permeability of the blood\u2013brain barrier","volume":"31","author":"Carman","year":"2011","journal-title":"J. Neurosci."},{"key":"10.1016\/j.mcn.2019.103414_bb0145","doi-asserted-by":"crossref","DOI":"10.1155\/2016\/2701526","article-title":"Role of NMDA receptor-mediated glutamatergic signaling in chronic and acute neuropathologies","volume":"2016","author":"Carvajal","year":"2016","journal-title":"Neural plasticity"},{"key":"10.1016\/j.mcn.2019.103414_bb0150","series-title":"Impact of Mitochondrial Dysfunction on Neurodegenerative Diseases: A Key Step on Alzheimer\u2019s Disease","author":"Celis-Mu\u00f1oz","year":"2016"},{"issue":"5","key":"10.1016\/j.mcn.2019.103414_bb0155","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/j.bbabio.2009.02.021","article-title":"Mitochondria, calcium and cell death: a deadly triad in neurodegeneration","volume":"1787","author":"Celsi","year":"2009","journal-title":"Biochimica et Biophysica Acta (BBA)-Bioenergetics"},{"issue":"8","key":"10.1016\/j.mcn.2019.103414_bb0160","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1007\/s11427-011-4205-7","article-title":"Early calcium dysregulation in Alzheimer\u2019s disease: setting the stage for synaptic dysfunction","volume":"54","author":"Chakroborty","year":"2011","journal-title":"Sci. China Life Sci."},{"issue":"24","key":"10.1016\/j.mcn.2019.103414_bb0165","doi-asserted-by":"crossref","first-page":"18195","DOI":"10.1074\/jbc.M000040200","article-title":"Presenilin-1 mutations increase levels of ryanodine receptors and calcium release in PC12 cells and cortical neurons","volume":"275","author":"Chan","year":"2000","journal-title":"J. Biol. Chem."},{"issue":"6","key":"10.1016\/j.mcn.2019.103414_bb0170","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1016\/j.neuron.2008.04.015","article-title":"Mechanism of Ca2+ disruption in Alzheimer's disease by presenilin regulation of InsP3 receptor channel gating","volume":"58","author":"Cheung","year":"2008","journal-title":"Neuron"},{"issue":"114","key":"10.1016\/j.mcn.2019.103414_bb0175","doi-asserted-by":"crossref","first-page":"ra22","DOI":"10.1126\/scisignal.2000818","article-title":"Gain-of-function enhancement of IP3 receptor modal gating by familial Alzheimer\u2019s disease\u2013linked presenilin mutants in human cells and mouse neurons","volume":"3","author":"Cheung","year":"2010","journal-title":"Sci. Signal."},{"issue":"2","key":"10.1016\/j.mcn.2019.103414_bb0180","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1111\/j.1474-9726.2007.00360.x","article-title":"Disrupted intracellular calcium regulates BACE1 gene expression via nuclear factor of activated T cells 1 (NFAT 1) signaling","volume":"7","author":"Cho","year":"2008","journal-title":"Aging Cell"},{"issue":"5","key":"10.1016\/j.mcn.2019.103414_bb0185","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1007\/s10571-017-0574-1","article-title":"Tau proteins and tauopathies in Alzheimer\u2019s disease","volume":"38","author":"Chong","year":"2018","journal-title":"Cell. Mol. Neurobiol."},{"issue":"4","key":"10.1016\/j.mcn.2019.103414_bb0190","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1007\/s11302-018-9629-0","article-title":"Role of purinergic receptors in the Alzheimer\u2019s disease","volume":"14","author":"Cie\u015blak","year":"2018","journal-title":"Purinergic signalling"},{"issue":"1","key":"10.1016\/j.mcn.2019.103414_bb0195","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1038\/nm0197-67","article-title":"Mutant presenilins of Alzheimer\u2019s disease increase production of 42-residue amyloid \u03b2-protein in both transfected cells and transgenic mice","volume":"3","author":"Citron","year":"1997","journal-title":"Nat. Med."},{"issue":"6","key":"10.1016\/j.mcn.2019.103414_bb0200","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.1016\/j.cell.2007.11.028","article-title":"Calcium signaling","volume":"131","author":"Clapham","year":"2007","journal-title":"Cell"},{"key":"10.1016\/j.mcn.2019.103414_bb0205","first-page":"1","article-title":"The amyloid-\u03b2 oligomer hypothesis: beginning of the third decade","author":"Cline","year":"2018","journal-title":"J. Alzheimers Dis."},{"key":"10.1016\/j.mcn.2019.103414_bb0210","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1186\/1750-1326-2-22","article-title":"The Alzheimer\u2019s disease beta-secretase enzyme, BACE1","volume":"2","author":"Cole","year":"2007","journal-title":"Mol. Neurodegener."},{"issue":"4","key":"10.1016\/j.mcn.2019.103414_bb0215","doi-asserted-by":"crossref","first-page":"2313","DOI":"10.1074\/jbc.R000024200","article-title":"Calcium, calcineurin, and the control of transcription","volume":"276","author":"Crabtree","year":"2001","journal-title":"J. Biol. Chem."},{"issue":"5","key":"10.1016\/j.mcn.2019.103414_bb0220","doi-asserted-by":"crossref","first-page":"515","DOI":"10.3892\/br.2016.625","article-title":"Nicotinic acetylcholine receptors and cancer","volume":"4","author":"Dang","year":"2016","journal-title":"Biomedical reports"},{"issue":"25","key":"10.1016\/j.mcn.2019.103414_bb0225","doi-asserted-by":"crossref","first-page":"22446","DOI":"10.1074\/jbc.M101740200","article-title":"Astrocytes regulate N-methyl-D-aspartate receptor subunit composition increasing neuronal sensitivity to excitotoxicity","volume":"276","author":"Daniels","year":"2001","journal-title":"J. Biol. Chem."},{"issue":"1","key":"10.1016\/j.mcn.2019.103414_bb0230","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1111\/j.1749-6632.1999.tb11281.x","article-title":"Molecular and functional diversity of voltage-gated calcium channels","volume":"868","author":"Davila","year":"1999","journal-title":"Ann. N. Y. Acad. Sci."},{"issue":"3","key":"10.1016\/j.mcn.2019.103414_bb0235","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1007\/s00221-003-1567-5","article-title":"A peptide derived from acetylcholinesterase induces neuronal cell death: characterisation of possible mechanisms","volume":"153","author":"Day","year":"2003","journal-title":"Exp. Brain Res."},{"issue":"1","key":"10.1016\/j.mcn.2019.103414_bb0240","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1186\/1750-1326-9-21","article-title":"Ryanodine receptors: physiological function and deregulation in Alzheimer disease","volume":"9","author":"Del Prete","year":"2014","journal-title":"Mol. Neurodegener."},{"issue":"9","key":"10.1016\/j.mcn.2019.103414_bb0245","doi-asserted-by":"crossref","first-page":"3824","DOI":"10.1523\/JNEUROSCI.4367-12.2013","article-title":"Cytotoxicity of intracellular a\u03b242 amyloid oligomers involves Ca2+ release from the endoplasmic reticulum by stimulated production of inositol trisphosphate","volume":"33","author":"Demuro","year":"2013","journal-title":"J. Neurosci."},{"issue":"17","key":"10.1016\/j.mcn.2019.103414_bb0250","doi-asserted-by":"crossref","first-page":"17294","DOI":"10.1074\/jbc.M500997200","article-title":"Calcium dysregulation and membrane disruption as a ubiquitous neurotoxic mechanism of soluble amyloid oligomers","volume":"280","author":"Demuro","year":"2005","journal-title":"J. Biol. Chem."},{"issue":"17","key":"10.1016\/j.mcn.2019.103414_bb0255","doi-asserted-by":"crossref","first-page":"12463","DOI":"10.1074\/jbc.R109.080895","article-title":"Calcium signaling and amyloid toxicity in Alzheimer disease","volume":"285","author":"Demuro","year":"2010","journal-title":"J. Biol. Chem."},{"issue":"8","key":"10.1016\/j.mcn.2019.103414_bb0260","doi-asserted-by":"crossref","first-page":"1816","DOI":"10.1016\/j.neurobiolaging.2011.09.040","article-title":"In vivo P2X7 inhibition reduces amyloid plaques in Alzheimer\u2019s disease through GSK3\u03b2 and secretases","volume":"33","author":"Diaz-Hernandez","year":"2012","journal-title":"Neurobiol. Aging"},{"issue":"2","key":"10.1016\/j.mcn.2019.103414_bb0265","doi-asserted-by":"crossref","first-page":"e34","DOI":"10.1371\/journal.pbio.0060034","article-title":"Caldendrin\u2013Jacob: a protein liaison that couples NMDA receptor signalling to the nucleus","volume":"6","author":"Dieterich","year":"2008","journal-title":"PLoS Biol."},{"key":"10.1016\/j.mcn.2019.103414_bb0270","doi-asserted-by":"crossref","first-page":"1232","DOI":"10.1016\/j.cell.2019.04.022","article-title":"Assembly of a GPCR-G protein complex","volume":"177","author":"Du","year":"2019","journal-title":"Cell"},{"key":"10.1016\/j.mcn.2019.103414_bb0275","series-title":"Seminars in Cell & Developmental Biology","article-title":"Disturbed calcium signaling in spinocerebellar ataxias and Alzheimer\u2019s disease","author":"Egorova","year":"2015"},{"issue":"6","key":"10.1016\/j.mcn.2019.103414_bb0280","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1016\/j.it.2016.04.004","article-title":"Purinergic signaling during immune cell trafficking","volume":"37","author":"Ferrari","year":"2016","journal-title":"Trends Immunol."},{"issue":"6","key":"10.1016\/j.mcn.2019.103414_bb0285","doi-asserted-by":"crossref","first-page":"872","DOI":"10.1002\/jnr.20135","article-title":"Involvement of endoplasmic reticulum Ca2+ release through ryanodine and inositol 1, 4, 5-triphosphate receptors in the neurotoxic effects induced by the amyloid-\u03b2 peptide","volume":"76","author":"Ferreiro","year":"2004","journal-title":"J. Neurosci. Res."},{"issue":"4","key":"10.1016\/j.mcn.2019.103414_bb0290","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1152\/physrev.00013.2002","article-title":"Ryanodine receptor calcium release channels","volume":"82","author":"Fill","year":"2002","journal-title":"Physiol. Rev."},{"issue":"3","key":"10.1016\/j.mcn.2019.103414_bb0295","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1111\/j.1474-9726.2007.00283.x","article-title":"Calcium homeostasis and modulation of synaptic plasticity in the aged brain","volume":"6","author":"Foster","year":"2007","journal-title":"Aging Cell"},{"key":"10.1016\/j.mcn.2019.103414_bb0300","doi-asserted-by":"crossref","unstructured":"Ghosh, A. and K.P. Giese, Calcium\/calmodulin-dependent kinase II and Alzheimer\u00e2\u20ac\u2122s disease. Molecular brain. 8(1): p. 78.","DOI":"10.1186\/s13041-015-0166-2"},{"issue":"S1","key":"10.1016\/j.mcn.2019.103414_bb0305","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1002\/gps.935","article-title":"Cholinergic function and Alzheimer\u2019s disease","volume":"18","author":"Giacobini","year":"2003","journal-title":"International journal of geriatric psychiatry"},{"issue":"4","key":"10.1016\/j.mcn.2019.103414_bb0310","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1016\/j.mcn.2007.12.010","article-title":"Extracellular tau promotes intracellular calcium increase through M1 and M3 muscarinic receptors in neuronal cells","volume":"37","author":"Gomez-Ramos","year":"2008","journal-title":"Mol. Cell. Neurosci."},{"key":"10.1016\/j.mcn.2019.103414_bb0315","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1016\/j.redox.2015.08.010","article-title":"Calcium and ROS: a mutual interplay","volume":"6","author":"G\u00f6rlach","year":"2015","journal-title":"Redox Biol."},{"issue":"2","key":"10.1016\/j.mcn.2019.103414_bb0320","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1016\/j.neuron.2008.07.013","article-title":"Linking calcium to A\u03b2 and Alzheimer's disease","volume":"59","author":"Green","year":"2008","journal-title":"Neuron"},{"issue":"7","key":"10.1016\/j.mcn.2019.103414_bb0325","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1083\/jcb.200706171","article-title":"SERCA pump activity is physiologically regulated by presenilin and regulates amyloid \u03b2 production","volume":"181","author":"Green","year":"2008","journal-title":"J. Cell Biol."},{"issue":"33","key":"10.1016\/j.mcn.2019.103414_bb0330","doi-asserted-by":"crossref","first-page":"17112","DOI":"10.1074\/jbc.M116.720664","article-title":"Oligomers of amyloid \u03b2 prevent physiological activation of the cellular prion protein-metabotropic glutamate receptor 5 complex by glutamate in Alzheimer disease","volume":"291","author":"Haas","year":"2016","journal-title":"J. Biol. Chem."},{"issue":"1_supplement","key":"10.1016\/j.mcn.2019.103414_bb0335","article-title":"Alteration of calcium and electrical dynamics in cerebrovascular endothelium during development of Alzheimer\u2019s disease","volume":"33","author":"Hakim","year":"2019","journal-title":"FASEB J."},{"issue":"9","key":"10.1016\/j.mcn.2019.103414_bb0340","doi-asserted-by":"crossref","first-page":"1859","DOI":"10.1016\/j.celrep.2016.04.077","article-title":"Chronic pharmacological mGluR5 inhibition prevents cognitive impairment and reduces pathogenesis in an Alzheimer disease mouse model","volume":"15","author":"Hamilton","year":"2016","journal-title":"Cell Rep."},{"key":"10.1016\/j.mcn.2019.103414_bb0345","doi-asserted-by":"crossref","first-page":"1264","DOI":"10.1002\/gps.1851","article-title":"Nilvadipine prevents cognitive decline in patients with mild cognitive impairment","volume":"22","author":"Hanyu","year":"2007","journal-title":"Intl J Geriatr Psychiatry"},{"issue":"9","key":"10.1016\/j.mcn.2019.103414_bb0350","doi-asserted-by":"crossref","first-page":"1933","DOI":"10.1016\/j.bbamem.2009.05.015","article-title":"Calcium enhances the proteolytic activity of BACE1: an in vitro biophysical and biochemical characterization of the BACE1-calcium interaction","volume":"1788","author":"Hayley","year":"2009","journal-title":"Biochim. Biophys. Acta"},{"issue":"5","key":"10.1016\/j.mcn.2019.103414_bb0355","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1016\/j.ceca.2008.03.004","article-title":"The N-terminus of presenilin-2 increases single channel activity of brain ryanodine receptors through direct protein\u2013protein interaction","volume":"44","author":"Hayrapetyan","year":"2008","journal-title":"Cell Calcium"},{"issue":"13","key":"10.1016\/j.mcn.2019.103414_bb0360","doi-asserted-by":"crossref","first-page":"6058","DOI":"10.1073\/pnas.0909586107","article-title":"Locus ceruleus controls Alzheimer\u2019s disease pathology by modulating microglial functions through norepinephrine","volume":"107","author":"Heneka","year":"2010","journal-title":"Proc. Natl. Acad. Sci."},{"issue":"4","key":"10.1016\/j.mcn.2019.103414_bb0365","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1016\/S1474-4422(15)70016-5","article-title":"Neuroinflammation in Alzheimer's disease","volume":"14","author":"Heneka","year":"2015","journal-title":"The Lancet Neurology"},{"issue":"1","key":"10.1016\/j.mcn.2019.103414_bb0370","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1007\/s00259-007-0699-4","article-title":"Acetylcholine esterase activity in mild cognitive impairment and Alzheimer\u2019s disease","volume":"35","author":"Herholz","year":"2008","journal-title":"Eur. J. Nucl. Med. Mol. Imaging"},{"issue":"11","key":"10.1016\/j.mcn.2019.103414_bb0375","doi-asserted-by":"crossref","first-page":"3008","DOI":"10.1111\/j.1460-9568.2006.05189.x","article-title":"Glutamate-mediated excitotoxicity in neonatal hippocampal neurons is mediated by mGluR-induced release of Ca++ from intracellular stores and is prevented by estradiol","volume":"24","author":"Hilton","year":"2006","journal-title":"Eur. J. Neurosci."},{"issue":"3","key":"10.1016\/j.mcn.2019.103414_bb0380","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1093\/ntr\/nty116","article-title":"Nicotinic acetylcholine receptor agonists for the treatment of Alzheimer\u2019s dementia: an update","volume":"21","author":"Hoskin","year":"2018","journal-title":"Nicotine Tob. Res."},{"issue":"3","key":"10.1016\/j.mcn.2019.103414_bb0385","doi-asserted-by":"crossref","first-page":"e2717","DOI":"10.1038\/cddis.2017.140","article-title":"Overexpression of EphB2 in hippocampus rescues impaired NMDA receptors trafficking and cognitive dysfunction in Alzheimer model","volume":"8","author":"Hu","year":"2017","journal-title":"Cell Death Dis."},{"issue":"5","key":"10.1016\/j.mcn.2019.103414_bb0390","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1016\/j.neuint.2004.03.007","article-title":"Glutamate-mediated excitotoxicity and neurodegeneration in Alzheimer\u2019s disease","volume":"45","author":"Hynd","year":"2004","journal-title":"Neurochem. Int."},{"issue":"2","key":"10.1016\/j.mcn.2019.103414_bb0395","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.neulet.2012.03.026","article-title":"M1 muscarinic acetylcholine receptor interacts with BACE1 and regulates its proteosomal degradation","volume":"515","author":"Jiang","year":"2012","journal-title":"Neurosci. Lett."},{"issue":"3","key":"10.1016\/j.mcn.2019.103414_bb0400","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1007\/s12035-013-8469-8","article-title":"\u03b2-Arrestins as potential therapeutic targets for Alzheimer\u2019s disease","volume":"48","author":"Jiang","year":"2013","journal-title":"Mol. Neurobiol."},{"key":"10.1016\/j.mcn.2019.103414_bb0405","series-title":"Progress in Molecular Biology and Translational Science","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1016\/B978-0-12-394440-5.00014-0","article-title":"\u03b2-Arrestins in the immune system","author":"Jiang","year":"2013"},{"issue":"2","key":"10.1016\/j.mcn.2019.103414_bb0410","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1007\/s12264-013-1406-z","article-title":"M1 muscarinic acetylcholine receptor in Alzheimer\u2019s disease","volume":"30","author":"Jiang","year":"2014","journal-title":"Neurosci. Bull."},{"key":"10.1016\/j.mcn.2019.103414_bb0415","doi-asserted-by":"crossref","unstructured":"Jiang, X., et al., Spatial training preserves associative memory capacity with augmentation of dendrite ramification and spine generation in Tg2576 mice. Sci. Rep.. 5: p. 9488.","DOI":"10.1038\/srep09488"},{"issue":"1","key":"10.1016\/j.mcn.2019.103414_bb0420","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.jaci.2005.11.012","article-title":"Molecular mechanisms of \u03b22-adrenergic receptor function, response, and regulation","volume":"117","author":"Johnson","year":"2006","journal-title":"J. Allergy Clin. Immunol."},{"issue":"1","key":"10.1016\/j.mcn.2019.103414_bb0425","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.coph.2005.09.007","article-title":"Mechanism of action of memantine","volume":"6","author":"Johnson","year":"2006","journal-title":"Curr. Opin. Pharmacol."},{"issue":"12","key":"10.1016\/j.mcn.2019.103414_bb0430","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1002\/bies.201300082","article-title":"Are nicotinic acetylcholine receptors coupled to G proteins?","volume":"35","author":"Kabbani","year":"2013","journal-title":"Bioessays"},{"issue":"24","key":"10.1016\/j.mcn.2019.103414_bb0435","doi-asserted-by":"crossref","first-page":"4803","DOI":"10.1007\/s00018-014-1706-0","article-title":"Amyloid beta receptors responsible for neurotoxicity and cellular defects in Alzheimer\u2019s disease","volume":"71","author":"Kam","year":"2014","journal-title":"Cell. Mol. Life Sci."},{"issue":"6","key":"10.1016\/j.mcn.2019.103414_bb0440","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1016\/S0092-8674(01)00497-4","article-title":"An important role of neural activity-dependent CaMKIV signaling in the consolidation of long-term memory","volume":"106","author":"Kang","year":"2001","journal-title":"Cell"},{"issue":"2","key":"10.1016\/j.mcn.2019.103414_bb0445","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/S1474-4422(10)70277-5","article-title":"Disrupted energy metabolism and neuronal circuit dysfunction in cognitive impairment and Alzheimer's disease","volume":"10","author":"Kapogiannis","year":"2011","journal-title":"The Lancet Neurology"},{"issue":"33","key":"10.1016\/j.mcn.2019.103414_bb0450","doi-asserted-by":"crossref","first-page":"20060","DOI":"10.1074\/jbc.M115.647040","article-title":"Identification and characterization of a G protein-binding cluster in \u03b17 nicotinic acetylcholine receptors","volume":"290","author":"King","year":"2015","journal-title":"J. Biol. Chem."},{"issue":"6972","key":"10.1016\/j.mcn.2019.103414_bb0455","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1038\/nature02246","article-title":"The mitochondrial calcium uniporter is a highly selective ion channel","volume":"427","author":"Kirichok","year":"2004","journal-title":"Nature"},{"key":"10.1016\/j.mcn.2019.103414_bb0460","doi-asserted-by":"crossref","DOI":"10.1038\/cddiscovery.2017.45","article-title":"DS16570511 is a small-molecule inhibitor of the mitochondrial calcium uniporter","volume":"3","author":"Kon","year":"2017","journal-title":"Cell death discovery"},{"issue":"1","key":"10.1016\/j.mcn.2019.103414_bb0465","doi-asserted-by":"crossref","first-page":"3864","DOI":"10.1038\/s41598-017-03651-7","article-title":"A small-molecule DS44170716 inhibits Ca 2+-induced mitochondrial permeability transition","volume":"7","author":"Kon","year":"2017","journal-title":"Sci. Rep."},{"issue":"1","key":"10.1016\/j.mcn.2019.103414_bb0470","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.bbrc.2015.02.004","article-title":"Ca2+ homeostasis and endoplasmic reticulum (ER) stress: an integrated view of calcium signaling","volume":"460","author":"Krebs","year":"2015","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"4","key":"10.1016\/j.mcn.2019.103414_bb0475","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1038\/icb.2015.15","article-title":"Chemokine and chemokine receptor structure and interactions: implications for therapeutic strategies","volume":"93","author":"Kufareva","year":"2015","journal-title":"Immunol. Cell Biol."},{"key":"10.1016\/j.mcn.2019.103414_bb0480","doi-asserted-by":"crossref","first-page":"215","DOI":"10.3389\/fnins.2015.00215","article-title":"Therapeutic potential of mGluR5 targeting in Alzheimer\u2019s disease","volume":"9","author":"Kumar","year":"2015","journal-title":"Front. Neurosci."},{"issue":"5","key":"10.1016\/j.mcn.2019.103414_bb0485","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1007\/s00401-017-1733-7","article-title":"Post-translational remodeling of ryanodine receptor induces calcium leak leading to Alzheimer\u2019s disease-like pathologies and cognitive deficits","volume":"134","author":"Lacampagne","year":"2017","journal-title":"Acta Neuropathol."},{"issue":"47","key":"10.1016\/j.mcn.2019.103414_bb0490","doi-asserted-by":"crossref","first-page":"16857","DOI":"10.1523\/JNEUROSCI.1858-12.2012","article-title":"The complex PrPc-Fyn couples human oligomeric A\u03b2 with pathological Tau changes in Alzheimer\u2019s disease","volume":"32","author":"Larson","year":"2012","journal-title":"J. Neurosci."},{"issue":"4","key":"10.1016\/j.mcn.2019.103414_bb0495","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1083\/jcb.149.4.793","article-title":"Capacitative calcium entry deficits and elevated luminal calcium content in mutant presenilin-1 knockin mice","volume":"149","author":"Leissring","year":"2000","journal-title":"J. Cell Biol."},{"issue":"8","key":"10.1016\/j.mcn.2019.103414_bb0500","doi-asserted-by":"crossref","DOI":"10.1111\/jne.12588","article-title":"Purinergic receptor types in the hypothalamic-neurohypophysial system","volume":"30","author":"Lemos","year":"2018","journal-title":"J. Neuroendocrinol."},{"issue":"6","key":"10.1016\/j.mcn.2019.103414_bb0505","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1038\/sj.bjp.0701021","article-title":"Metabotropic glutamate receptor subtypes mediating slow inward tail current (IADP) induction and inhibition of synaptic transmission in olfactory cortical neurones","volume":"120","author":"Libri","year":"1997","journal-title":"Br. J. Pharmacol."},{"issue":"3","key":"10.1016\/j.mcn.2019.103414_bb0510","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1038\/nrn753","article-title":"The molecular basis of CaMKII function in synaptic and behavioural memory","volume":"3","author":"Lisman","year":"2002","journal-title":"Nat. Rev. Neurosci."},{"issue":"5","key":"10.1016\/j.mcn.2019.103414_bb0515","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.1016\/j.cell.2012.06.052","article-title":"Role of leaky neuronal ryanodine receptors in stress-induced cognitive dysfunction","volume":"150","author":"Liu","year":"2012","journal-title":"Cell"},{"issue":"3","key":"10.1016\/j.mcn.2019.103414_bb0520","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1038\/cr.2012.167","article-title":"\u03b2-arrestin1 regulates \u03b3-secretase complex assembly and modulates amyloid-\u03b2 pathology","volume":"23","author":"Liu","year":"2013","journal-title":"Cell Res."},{"key":"10.1016\/j.mcn.2019.103414_bb0525","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.neulet.2016.07.039","article-title":"Down-regulation of purinergic P2X7 receptor expression and intracellular calcium dysregulation in peripheral blood mononuclear cells of patients with amyotrophic lateral sclerosis","volume":"630","author":"Liu","year":"2016","journal-title":"Neurosci. Lett."},{"issue":"1","key":"10.1016\/j.mcn.2019.103414_bb0530","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1515\/revneuro-2015-0016","article-title":"CXCL12\/CXCR4 axis: an emerging neuromodulator in pathological pain","volume":"27","author":"Luo","year":"2016","journal-title":"Rev. Neurosci."},{"issue":"4","key":"10.1016\/j.mcn.2019.103414_bb0535","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1016\/j.neuron.2010.01.016","article-title":"Group 1 mGluR-dependent synaptic long-term depression: mechanisms and implications for circuitry and disease","volume":"65","author":"L\u00fcscher","year":"2010","journal-title":"Neuron"},{"issue":"6","key":"10.1016\/j.mcn.2019.103414_bb0540","doi-asserted-by":"crossref","first-page":"a005710","DOI":"10.1101\/cshperspect.a005710","article-title":"NMDA receptor-dependent long-term potentiation and long-term depression (LTP\/LTD)","volume":"4","author":"L\u00fcscher","year":"2012","journal-title":"Cold Spring Harb. Perspect. Biol."},{"issue":"3","key":"10.1016\/j.mcn.2019.103414_bb0545","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1242\/jcs.115.3.455","article-title":"The role of \u03b2-arrestins in the termination and transduction of G-protein-coupled receptor signals","volume":"115","author":"Luttrell","year":"2002","journal-title":"J. Cell Sci."},{"issue":"1","key":"10.1016\/j.mcn.2019.103414_bb0550","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1038\/s41380-018-0108-3","article-title":"New role of P2X7 receptor in an Alzheimer\u2019s disease mouse model","volume":"24","author":"Martin","year":"2019","journal-title":"Mol. Psychiatry"},{"issue":"8","key":"10.1016\/j.mcn.2019.103414_bb0555","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1002\/bies.1103","article-title":"Presenilin mutations and calcium signaling defects in the nervous and immune systems","volume":"23","author":"Mattson","year":"2001","journal-title":"Bioessays"},{"issue":"9","key":"10.1016\/j.mcn.2019.103414_bb0560","doi-asserted-by":"crossref","first-page":"1640","DOI":"10.1039\/C001975E","article-title":"Using a genetically targeted sensor to investigate the role of presenilin-1 in ER Ca 2+ levels and dynamics","volume":"6","author":"McCombs","year":"2010","journal-title":"Mol. BioSyst."},{"issue":"49","key":"10.1016\/j.mcn.2019.103414_bb0565","doi-asserted-by":"crossref","first-page":"40892","DOI":"10.1074\/jbc.M506623200","article-title":"The type III inositol 1, 4, 5-trisphosphate receptor preferentially transmits apoptotic Ca2+ signals into mitochondria","volume":"280","author":"Mendes","year":"2005","journal-title":"J. Biol. Chem."},{"issue":"1","key":"10.1016\/j.mcn.2019.103414_bb0570","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1002\/jcp.24695","article-title":"CXCR4\/CXCR7 molecular involvement in neuronal and neural progenitor migration: focus in CNS repair","volume":"230","author":"Merino","year":"2015","journal-title":"J. Cell. Physiol."},{"issue":"6765","key":"10.1016\/j.mcn.2019.103414_bb0575","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1038\/47513","article-title":"Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-\u03b2","volume":"403","author":"Nakagawa","year":"2000","journal-title":"Nature"},{"issue":"4","key":"10.1016\/j.mcn.2019.103414_bb0580","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1046\/j.1471-4159.2001.00478.x","article-title":"Deficiency of presenilin-1 increases calcium-dependent vulnerability of neurons to oxidative stress in vitro","volume":"78","author":"Nakajima","year":"2001","journal-title":"J. Neurochem."},{"issue":"10","key":"10.1016\/j.mcn.2019.103414_bb0585","doi-asserted-by":"crossref","first-page":"2047","DOI":"10.1016\/j.febslet.2007.04.041","article-title":"Brain-derived neurotrophic factor regulates AMPA receptor trafficking to post-synaptic densities via IP3R and TRPC calcium signaling","volume":"581","author":"Nakata","year":"2007","journal-title":"FEBS Lett."},{"issue":"9","key":"10.1016\/j.mcn.2019.103414_bb0590","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0074680","article-title":"Gpr3 stimulates A\u03b2 production via interactions with APP and \u03b2-arrestin2","volume":"8","author":"Nelson","year":"2013","journal-title":"PLoS One"},{"issue":"12","key":"10.1016\/j.mcn.2019.103414_bb0595","doi-asserted-by":"crossref","first-page":"1390","DOI":"10.1038\/nm1485","article-title":"Activation of \u00ce2 2-adrenergic receptor stimulates \u00ce3-secretase activity and accelerates amyloid plaque formation","volume":"12","author":"Ni","year":"2006","journal-title":"Nat. Med."},{"issue":"12","key":"10.1016\/j.mcn.2019.103414_bb0600","doi-asserted-by":"crossref","first-page":"1390","DOI":"10.1038\/nm1485","article-title":"Activation of \u03b2 2-adrenergic receptor stimulates \u03b3-secretase activity and accelerates amyloid plaque formation","volume":"12","author":"Ni","year":"2006","journal-title":"Nat. Med."},{"issue":"14","key":"10.1016\/j.mcn.2019.103414_bb0605","doi-asserted-by":"crossref","first-page":"5353","DOI":"10.1523\/JNEUROSCI.0282-11.2011","article-title":"EphB controls NMDA receptor function and synaptic targeting in a subunit-specific manner","volume":"31","author":"Nolt","year":"2011","journal-title":"J. Neurosci."},{"issue":"1\u20132","key":"10.1016\/j.mcn.2019.103414_bb0610","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.neulet.2005.08.024","article-title":"Mechanism of impairment of long-term potentiation by amyloid \u03b2 is independent of NMDA receptors or voltage-dependent calcium channels in hippocampal CA1 pyramidal neurons","volume":"391","author":"Nomura","year":"2005","journal-title":"Neurosci. Lett."},{"issue":"3","key":"10.1016\/j.mcn.2019.103414_bb0615","doi-asserted-by":"crossref","DOI":"10.1002\/14651858.CD001747","article-title":"Galantamine for Alzheimer\u2019s disease","author":"Olin","year":"2002","journal-title":"Cochrane Database Syst. Rev."},{"key":"10.1016\/j.mcn.2019.103414_bb0620","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1016\/j.neuropharm.2015.10.008","article-title":"Purinergic receptors in embryonic and adult neurogenesis","volume":"104","author":"Oliveira","year":"2016","journal-title":"Neuropharmacology"},{"issue":"3","key":"10.1016\/j.mcn.2019.103414_bb0625","doi-asserted-by":"crossref","first-page":"2471","DOI":"10.1111\/ejn.12599","article-title":"Apoptosis induced by A\u03b225\u201335 peptide is Ca2+-IP 3 signaling-dependent in murine astrocytes","volume":"40","author":"Oseki","year":"2014","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.mcn.2019.103414_bb0630","doi-asserted-by":"crossref","DOI":"10.1155\/2013\/185463","article-title":"The role of astrocytes in the regulation of synaptic plasticity and memory formation","volume":"2013","author":"Ota","year":"2013","journal-title":"Neural plasticity"},{"issue":"4","key":"10.1016\/j.mcn.2019.103414_bb0635","doi-asserted-by":"crossref","DOI":"10.1111\/acel.12793","article-title":"Mitochondria and aging: a role for the mitochondrial transition pore?","volume":"17","author":"Panel","year":"2018","journal-title":"Aging Cell"},{"issue":"2","key":"10.1016\/j.mcn.2019.103414_bb0640","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.nbd.2007.07.001","article-title":"Reduced CXCL12\/CXCR4 results in impaired learning and is downregulated in a mouse model of Alzheimer disease","volume":"28","author":"Parachikova","year":"2007","journal-title":"Neurobiol. Dis."},{"key":"10.1016\/j.mcn.2019.103414_bb0645","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.expneurol.2013.09.001","article-title":"Presenilins regulate the cellular activity of ryanodine receptors differentially through isotype-specific N-terminal cysteines","volume":"250","author":"Payne","year":"2013","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.mcn.2019.103414_bb0650","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.ceca.2017.06.008","article-title":"Calcium signaling and molecular mechanisms underlying neurodegenerative diseases","volume":"70","author":"Pchitskaya","year":"2018","journal-title":"Cell Calcium"},{"issue":"4","key":"10.1016\/j.mcn.2019.103414_bb0655","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1002\/mus.20745","article-title":"SERCA pump isoforms: their role in calcium transport and disease","volume":"35","author":"Periasamy","year":"2007","journal-title":"Muscle & Nerve: Official Journal of the American Association of Electrodiagnostic Medicine"},{"issue":"3","key":"10.1016\/j.mcn.2019.103414_bb0660","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1124\/pr.116.013367","article-title":"The diverse roles of arrestin scaffolds in G protein\u2013coupled receptor signaling","volume":"69","author":"Peterson","year":"2017","journal-title":"Pharmacol. Rev."},{"issue":"2","key":"10.1016\/j.mcn.2019.103414_bb0665","doi-asserted-by":"crossref","first-page":"492","DOI":"10.2741\/2695","article-title":"Neuroprotection via nAChRs: the role of nAChRs in neurodegenerative disorders such as Alzheimer\u2019s and Parkinson\u2019s disease","volume":"13","author":"Picciotto","year":"2008","journal-title":"Front. Biosci."},{"issue":"5","key":"10.1016\/j.mcn.2019.103414_bb0670","doi-asserted-by":"crossref","first-page":"1140","DOI":"10.1046\/j.1471-4159.2003.02227.x","article-title":"Intraneuronal amyloid-\u03b21-42 production triggered by sustained increase of cytosolic calcium concentration induces neuronal death","volume":"88","author":"Pierrot","year":"2004","journal-title":"J. Neurochem."},{"key":"10.1016\/j.mcn.2019.103414_bb0675","doi-asserted-by":"crossref","first-page":"29","DOI":"10.3389\/fnmol.2013.00029","article-title":"Role of endoplasmic reticulum Ca2+ signaling in the pathogenesis of Alzheimer disease","volume":"6","author":"Popugaeva","year":"2013","journal-title":"Front. Mol. Neurosci."},{"issue":"1_supplement","key":"10.1016\/j.mcn.2019.103414_bb0680","article-title":"Decreased levels of Beta-Arrestin 1 in brains of patients with Alzheimer\u2019s disease","volume":"32","author":"Potter","year":"2018","journal-title":"FASEB J."},{"issue":"2","key":"10.1016\/j.mcn.2019.103414_bb0685","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0117555","article-title":"Preventing effect of L-type calcium channel blockade on electrophysiological alterations in dentate gyrus granule cells induced by entorhinal amyloid pathology","volume":"10","author":"Pourbadie","year":"2015","journal-title":"PLoS One"},{"issue":"4","key":"10.1016\/j.mcn.2019.103414_bb0690","doi-asserted-by":"crossref","first-page":"1383","DOI":"10.1152\/physrev.00020.2014","article-title":"Store-operated calcium channels","volume":"95","author":"Prakriya","year":"2015","journal-title":"Physiol. Rev."},{"issue":"6226","key":"10.1016\/j.mcn.2019.103414_bb0695","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.1126\/science.1261064","article-title":"Crystal structure of the chemokine receptor CXCR4 in complex with a viral chemokine","volume":"347","author":"Qin","year":"2015","journal-title":"Science"},{"issue":"6","key":"10.1016\/j.mcn.2019.103414_bb0700","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1176\/ajp.2007.164.6.967","article-title":"Preventive effect of \u00ce2-adrenoceptor blockade on glucocorticoid-induced memory retrieval deficits","volume":"164","author":"de Quervain","year":"2007","journal-title":"Am. J. Psychiatr."},{"issue":"7366","key":"10.1016\/j.mcn.2019.103414_bb0705","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1038\/nature10361","article-title":"Crystal structure of the \u03b2 2 adrenergic receptor\u2013Gs protein complex","volume":"477","author":"Rasmussen","year":"2011","journal-title":"Nature"},{"issue":"3","key":"10.1016\/j.mcn.2019.103414_bb0710","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1016\/j.ceca.2011.04.007","article-title":"Mitochondrial permeability transition in Ca2+-dependent apoptosis and necrosis","volume":"50","author":"Rasola","year":"2011","journal-title":"Cell Calcium"},{"key":"10.1016\/j.mcn.2019.103414_bb0715","doi-asserted-by":"crossref","unstructured":"LC. Reese and G. Taglialatela, A role for calcineurin in Alzheimer's disease. Curr. Neuropharmacol.. 9(4): p. 685-692.","DOI":"10.2174\/157015911798376316"},{"issue":"5","key":"10.1016\/j.mcn.2019.103414_bb0720","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1016\/j.neurobiolaging.2006.03.006","article-title":"Efficacy of MEM 1003, a novel calcium channel blocker, in delay and trace eyeblink conditioning in older rabbits","volume":"28","author":"Rose","year":"2007","journal-title":"Neurobiol. Aging"},{"issue":"7245","key":"10.1016\/j.mcn.2019.103414_bb0725","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1038\/nature08144","article-title":"The structure and function of G-protein-coupled receptors","volume":"459","author":"Rosenbaum","year":"2009","journal-title":"Nature"},{"issue":"1\u20133","key":"10.1016\/j.mcn.2019.103414_bb0730","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1385\/MN:24:1-3:107","article-title":"Molecular mechanisms of glutamate receptor-mediated excitotoxic neuronal cell death","volume":"24","author":"Sattler","year":"2001","journal-title":"Mol. Neurobiol."},{"issue":"2","key":"10.1016\/j.mcn.2019.103414_bb0735","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1152\/physrev.2001.81.2.741","article-title":"Alzheimer\u2019s disease: genes, proteins, and therapy","volume":"81","author":"Selkoe","year":"2001","journal-title":"Physiol. Rev."},{"issue":"6","key":"10.1016\/j.mcn.2019.103414_bb0740","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1038\/aps.2009.64","article-title":"Nicotinic acetylcholine receptor-mediated calcium signaling in the nervous system","volume":"30","author":"Shen","year":"2009","journal-title":"Acta Pharmacol. Sin."},{"issue":"2","key":"10.1016\/j.mcn.2019.103414_bb0745","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1177\/1073858404270899","article-title":"Calcium dysregulation, IP3 signaling, and Alzheimer\u2019s disease","volume":"11","author":"Stutzmann","year":"2005","journal-title":"Neuroscientist"},{"issue":"2","key":"10.1016\/j.mcn.2019.103414_bb0750","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1523\/JNEUROSCI.4386-03.2004","article-title":"Dysregulated IP3 signaling in cortical neurons of knock-in mice expressing an Alzheimer\u2019s-linked mutation in presenilin1 results in exaggerated Ca2+ signals and altered membrane excitability","volume":"24","author":"Stutzmann","year":"2004","journal-title":"J. Neurosci."},{"issue":"1","key":"10.1016\/j.mcn.2019.103414_bb0755","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1196\/annals.1379.025","article-title":"Enhanced ryanodine-mediated calcium release in mutant PS1-expressing Alzheimer\u2019s mouse models","volume":"1097","author":"Stutzmann","year":"2007","journal-title":"Ann. N. Y. Acad. Sci."},{"issue":"4","key":"10.1016\/j.mcn.2019.103414_bb0760","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1038\/s41593-018-0080-x","article-title":"Imbalance between firing homeostasis and synaptic plasticity drives early-phase Alzheimer\u2019s disease","volume":"21","author":"Styr","year":"2018","journal-title":"Nat. Neurosci."},{"issue":"1","key":"10.1016\/j.mcn.2019.103414_bb0765","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.neuron.2014.02.019","article-title":"Reduced synaptic STIM2 expression and impaired store-operated calcium entry cause destabilization of mature spines in mutant presenilin mice","volume":"82","author":"Sun","year":"2014","journal-title":"Neuron"},{"issue":"2","key":"10.1016\/j.mcn.2019.103414_bb0770","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/j.ceca.2009.12.014","article-title":"The dysregulation of intracellular calcium in Alzheimer disease","volume":"47","author":"Supnet","year":"2010","journal-title":"Cell Calcium"},{"key":"10.1016\/j.mcn.2019.103414_bb0775","doi-asserted-by":"crossref","unstructured":"Supnet, C. and I. Bezprozvanny, Neuronal calcium signaling, mitochondrial dysfunction, and Alzheimer's disease. J. Alzheimers Dis.. 20(s2): p. S487-S498.","DOI":"10.3233\/JAD-2010-100306"},{"issue":"50","key":"10.1016\/j.mcn.2019.103414_bb0780","doi-asserted-by":"crossref","first-page":"38440","DOI":"10.1074\/jbc.M606736200","article-title":"Amyloid-\u03b2-(1-42) increases ryanodine receptor-3 expression and function in neurons of TgCRND8 mice","volume":"281","author":"Supnet","year":"2006","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.mcn.2019.103414_bb0785","first-page":"1","article-title":"Age-related shift in LTD is dependent on neuronal adenosine A 2A receptors interplay with mGluR5 and NMDA receptors","author":"Temido-Ferreira","year":"2018","journal-title":"Mol. Psychiatry"},{"issue":"2","key":"10.1016\/j.mcn.2019.103414_bb0790","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1038\/nrn2977","article-title":"The role of G protein-coupled receptors in the pathology of Alzheimer\u2019s disease","volume":"12","author":"Thathiah","year":"2011","journal-title":"Nat. Rev. Neurosci."},{"issue":"1","key":"10.1016\/j.mcn.2019.103414_bb0795","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1038\/nm.3023","article-title":"\u03b2-Arrestin 2 regulates A\u03b2 generation and \u03b3-secretase activity in Alzheimer\u2019s disease","volume":"19","author":"Thathiah","year":"2013","journal-title":"Nat. Med."},{"issue":"3","key":"10.1016\/j.mcn.2019.103414_bb0800","doi-asserted-by":"crossref","first-page":"1727","DOI":"10.1152\/jn.00771.2005","article-title":"Synaptic and extrasynaptic NMDA receptor NR2 subunits in cultured hippocampal neurons","volume":"95","author":"Thomas","year":"2006","journal-title":"J. Neurophysiol."},{"issue":"1","key":"10.1016\/j.mcn.2019.103414_bb0805","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1007\/s12603-014-0511-7","article-title":"Brain metabolism and Alzheimer\u2019s disease: the prospect of a metabolite-based therapy","volume":"19","author":"Thomas","year":"2015","journal-title":"J. Nutr. Health Aging"},{"issue":"5","key":"10.1016\/j.mcn.2019.103414_bb0810","first-page":"4374","article-title":"CXCL12 induces migration of oligodendrocyte precursor cells through the CXCR4-activated MEK\/ERK and PI3K\/AKT pathways","volume":"18","author":"Tian","year":"2018","journal-title":"Mol. Med. Rep."},{"issue":"5","key":"10.1016\/j.mcn.2019.103414_bb0815","doi-asserted-by":"crossref","first-page":"2025","DOI":"10.1073\/pnas.94.5.2025","article-title":"The presenilin 2 mutation (N141I) linked to familial Alzheimer disease (Volga German families) increases the secretion of amyloid \u03b2 protein ending at the 42nd (or 43rd) residue","volume":"94","author":"Tomita","year":"1997","journal-title":"Proc. Natl. Acad. Sci."},{"issue":"5","key":"10.1016\/j.mcn.2019.103414_bb0820","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1016\/j.cell.2006.06.059","article-title":"Presenilins form ER Ca2+ leak channels, a function disrupted by familial Alzheimer's disease-linked mutations","volume":"126","author":"Tu","year":"2006","journal-title":"Cell"},{"issue":"1","key":"10.1016\/j.mcn.2019.103414_bb0825","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1046\/j.1471-4159.1997.68010265.x","article-title":"Amyloid \u03b2 protein potentiates Ca2+ influx through L-type voltage-sensitive Ca2+ channels: a possible involvement of free radicals","volume":"68","author":"Ueda","year":"1997","journal-title":"J. Neurochem."},{"issue":"1","key":"10.1016\/j.mcn.2019.103414_bb0830","doi-asserted-by":"crossref","first-page":"37","DOI":"10.4161\/pri.22212","article-title":"Amyloid-\u03b2 induced signaling by cellular prion protein and Fyn kinase in Alzheimer disease","volume":"7","author":"Um","year":"2013","journal-title":"Prion"},{"issue":"9","key":"10.1016\/j.mcn.2019.103414_bb0835","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.1038\/nn.3178","article-title":"Alzheimer amyloid-\u03b2 oligomer bound to postsynaptic prion protein activates Fyn to impair neurons","volume":"15","author":"Um","year":"2012","journal-title":"Nat. Neurosci."},{"issue":"5","key":"10.1016\/j.mcn.2019.103414_bb0840","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1016\/j.neuron.2013.06.036","article-title":"Metabotropic glutamate receptor 5 is a coreceptor for Alzheimer a\u03b2 oligomer bound to cellular prion protein","volume":"79","author":"Um","year":"2013","journal-title":"Neuron"},{"issue":"13","key":"10.1016\/j.mcn.2019.103414_bb0845","doi-asserted-by":"crossref","first-page":"7248","DOI":"10.1016\/S0021-9258(19)39106-9","article-title":"Phospholipid synthesis in a membrane fraction associated with mitochondria","volume":"265","author":"Vance","year":"1990","journal-title":"J. Biol. Chem."},{"issue":"4","key":"10.1016\/j.mcn.2019.103414_bb0850","doi-asserted-by":"crossref","first-page":"1041","DOI":"10.3233\/JAD-160763","article-title":"Role of glutamate and NMDA receptors in Alzheimer\u2019s disease","volume":"57","author":"Wang","year":"2017","journal-title":"J. Alzheimers Dis."},{"issue":"3","key":"10.1016\/j.mcn.2019.103414_bb0855","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/S0014-5793(04)00253-4","article-title":"L-type voltage-gated calcium channels: understanding function through structure","volume":"564","author":"Wang","year":"2004","journal-title":"FEBS Lett."},{"issue":"12","key":"10.1016\/j.mcn.2019.103414_bb0860","doi-asserted-by":"crossref","first-page":"2321","DOI":"10.1016\/j.neurobiolaging.2010.05.004","article-title":"Carvedilol as a potential novel agent for the treatment of Alzheimer\u2019s disease","volume":"32","author":"Wang","year":"2011","journal-title":"Neurobiol. Aging"},{"issue":"8","key":"10.1016\/j.mcn.2019.103414_bb0865","doi-asserted-by":"crossref","first-page":"1240","DOI":"10.1016\/j.bbadis.2013.10.015","article-title":"Oxidative stress and mitochondrial dysfunction in Alzheimer's disease","volume":"1842","author":"Wang","year":"2014","journal-title":"Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease"},{"issue":"5","key":"10.1016\/j.mcn.2019.103414_bb0870","doi-asserted-by":"crossref","DOI":"10.4172\/2161-0460.1000374","article-title":"Calcium dysregulation in Alzheimer\u2019s disease: a target for new drug development","volume":"7","author":"Wang","year":"2017","journal-title":"Journal of Alzheimer\u2019s disease & Parkinsonism"},{"key":"10.1016\/j.mcn.2019.103414_bb0875","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1146\/annurev-biochem-060614-033910","article-title":"The molecular basis of G protein\u2013coupled receptor activation","volume":"87","author":"Weis","year":"2018","journal-title":"Annu. Rev. Biochem."},{"issue":"3","key":"10.1016\/j.mcn.2019.103414_bb0880","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1007\/s11302-012-9307-6","article-title":"Neuroprotective roles of the P2Y 2 receptor","volume":"8","author":"Weisman","year":"2012","journal-title":"Purinergic signalling"},{"issue":"26","key":"10.1016\/j.mcn.2019.103414_bb0885","doi-asserted-by":"crossref","first-page":"10479","DOI":"10.1073\/pnas.1300410110","article-title":"Mitochondrial calcium uptake","volume":"110","author":"Williams","year":"2013","journal-title":"Proc. Natl. Acad. Sci."},{"issue":"26","key":"10.1016\/j.mcn.2019.103414_bb0890","doi-asserted-by":"crossref","first-page":"7931","DOI":"10.1021\/bi060799c","article-title":"The \u03b3-secretase complex: membrane-embedded proteolytic ensemble","volume":"45","author":"Wolfe","year":"2006","journal-title":"Biochemistry"},{"issue":"7","key":"10.1016\/j.mcn.2019.103414_bb0895","first-page":"C790","article-title":"P2X7 receptor activation induces inflammatory responses in salivary gland epithelium","volume":"303","author":"Woods","year":"2012","journal-title":"Am. J. Phys. Cell Phys."},{"issue":"9","key":"10.1016\/j.mcn.2019.103414_bb0900","doi-asserted-by":"crossref","first-page":"1499","DOI":"10.4103\/1673-5374.215261","article-title":"Blocking beta 2-adrenergic receptor inhibits dendrite ramification in a mouse model of Alzheimer\u2019s disease","volume":"12","author":"Wu","year":"2017","journal-title":"Neural Regen. Res."},{"issue":"1\u20132","key":"10.1016\/j.mcn.2019.103414_bb0905","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/S0165-5728(00)00285-X","article-title":"Expression of the chemokine receptor CXCR3 on neurons and the elevated expression of its ligand IP-10 in reactive astrocytes: in vitro ERK1\/2 activation and role in Alzheimer\u2019s disease","volume":"108","author":"Xia","year":"2000","journal-title":"J. Neuroimmunol."},{"issue":"6","key":"10.1016\/j.mcn.2019.103414_bb0910","doi-asserted-by":"crossref","first-page":"1153","DOI":"10.1016\/j.bcp.2003.11.005","article-title":"Protective effects of a selective L-type voltage-sensitive calcium channel blocker, S-312-d, on neuronal cell death","volume":"67","author":"Yagami","year":"2004","journal-title":"Biochem. Pharmacol."},{"issue":"3","key":"10.1016\/j.mcn.2019.103414_bb0915","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1016\/j.pneurobio.2009.07.009","article-title":"Calcium dysregulation in Alzheimer\u2019s disease: from mechanisms to therapeutic opportunities","volume":"89","author":"Yu","year":"2009","journal-title":"Prog. Neurobiol."},{"key":"10.1016\/j.mcn.2019.103414_bb0920","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/j.brainres.2009.12.087","article-title":"Blocking \u03b22-adrenergic receptor attenuates acute stress-induced amyloid \u03b2 peptides production","volume":"1317","author":"Yu","year":"2010","journal-title":"Brain Res."},{"issue":"7","key":"10.1016\/j.mcn.2019.103414_bb0925","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1007\/s10072-016-2546-5","article-title":"Dysfunction of NMDA receptors in Alzheimer\u2019s disease","volume":"37","author":"Zhang","year":"2016","journal-title":"Neurol. Sci."},{"key":"10.1016\/j.mcn.2019.103414_bb0930","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/j.isci.2018.07.018","article-title":"Soluble A\u03b2 oligomers impair dipolar heterodendritic plasticity by activation of mGluR in the Hippocampal CA1 region","volume":"6","author":"Zhao","year":"2018","journal-title":"iScience"},{"key":"10.1016\/j.mcn.2019.103414_bb0935","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.brainresbull.2015.04.002","article-title":"NMDA receptor NR2B subunits contribute to PTZ-kindling-induced hippocampal astrocytosis and oxidative stress","volume":"114","author":"Zhu","year":"2015","journal-title":"Brain Res. Bull."},{"issue":"2","key":"10.1016\/j.mcn.2019.103414_bb0940","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1002\/jnr.20152","article-title":"Beta-secretase BACE1 is differentially controlled through muscarinic acetylcholine receptor signaling","volume":"77","author":"Zuchner","year":"2004","journal-title":"J. Neurosci. Res."},{"issue":"7","key":"10.1016\/j.mcn.2019.103414_bb0945","doi-asserted-by":"crossref","first-page":"1275","DOI":"10.1089\/ars.2010.3359","article-title":"Calcium dysregulation and homeostasis of neural calcium in the molecular mechanisms of neurodegenerative diseases provide multiple targets for neuroprotection","volume":"14","author":"Z\u00fcndorf","year":"2011","journal-title":"Antioxid. Redox Signal."}],"container-title":["Molecular and Cellular Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1044743119302192?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1044743119302192?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T10:50:33Z","timestamp":1778583033000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1044743119302192"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,12]]},"references-count":189,"alternative-id":["S1044743119302192"],"URL":"https:\/\/doi.org\/10.1016\/j.mcn.2019.103414","relation":{},"ISSN":["1044-7431"],"issn-type":[{"value":"1044-7431","type":"print"}],"subject":[],"published":{"date-parts":[[2019,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Role of GPCR signaling and calcium dysregulation in Alzheimer's disease","name":"articletitle","label":"Article Title"},{"value":"Molecular and Cellular Neuroscience","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.mcn.2019.103414","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"103414"}}