{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T13:51:47Z","timestamp":1793713907619,"version":"4.6.1"},"reference-count":64,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2009,1,1]],"date-time":"2009-01-01T00:00:00Z","timestamp":1230768000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medical Clinics of North America"],"published-print":{"date-parts":[[2009,1]]},"DOI":"10.1016\/j.mcna.2008.09.006","type":"journal-article","created":{"date-parts":[[2008,12,6]],"date-time":"2008-12-06T09:24:02Z","timestamp":1228555442000},"page":"25-35","source":"Crossref","is-referenced-by-count":118,"title":["Role of Bone in Osteoarthritis Pathogenesis"],"prefix":"10.1016","volume":"93","author":[{"given":"Steven R.","family":"Goldring","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"Suppl A","key":"10.1016\/j.mcna.2008.09.006_bib1","doi-asserted-by":"crossref","first-page":"S10","DOI":"10.1016\/j.joca.2003.09.007","article-title":"Subchondral bone changes in hand and knee osteoarthritis detected by radiography","volume":"12","author":"Buckland-Wright","year":"2004","journal-title":"Osteoarthr Cartil"},{"issue":"Suppl A","key":"10.1016\/j.mcna.2008.09.006_bib2","doi-asserted-by":"crossref","first-page":"S2","DOI":"10.1016\/j.joca.2003.09.010","article-title":"The role of joint architecture in the etiology of arthritis","volume":"12","author":"Bullough","year":"2004","journal-title":"Osteoarthr Cartil"},{"issue":"Suppl A","key":"10.1016\/j.mcna.2008.09.006_bib3","doi-asserted-by":"crossref","first-page":"S20","DOI":"10.1016\/j.joca.2003.09.016","article-title":"Anatomy and physiology of the mineralized tissues: role in the pathogenesis of osteoarthrosis","volume":"12","author":"Burr","year":"2004","journal-title":"Osteoarthr Cartil"},{"issue":"2","key":"10.1016\/j.mcna.2008.09.006_bib4","first-page":"118","article-title":"Perspective: genetic and hormonal roles in bone disorders: insights of an updated bone physiology","volume":"3","author":"Frost","year":"2003","journal-title":"J Musculoskelet Neuronal Interact"},{"issue":"4","key":"10.1016\/j.mcna.2008.09.006_bib5","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1002\/(SICI)1097-0029(19970515)37:4<343::AID-JEMT9>3.0.CO;2-L","article-title":"The involvement of subchondral mineralized tissues in osteoarthrosis: quantitative microscopic evidence","volume":"37","author":"Burr","year":"1997","journal-title":"Microsc Res Tech"},{"issue":"2","key":"10.1016\/j.mcna.2008.09.006_bib6","doi-asserted-by":"crossref","first-page":"427","DOI":"10.2353\/ajpath.2007.060834","article-title":"Osteoclasts: what do they do and how do they do it?","volume":"170","author":"Teitelbaum","year":"2007","journal-title":"Am J Pathol"},{"issue":"8","key":"10.1016\/j.mcna.2008.09.006_bib7","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1038\/nrg1122","article-title":"Genetic regulation of osteoclast development and function","volume":"4","author":"Teitelbaum","year":"2003","journal-title":"Nat Rev Genet"},{"issue":"6","key":"10.1016\/j.mcna.2008.09.006_bib8","doi-asserted-by":"crossref","first-page":"1574","DOI":"10.1016\/j.bone.2007.02.023","article-title":"Targeted bone remodeling involves BMU steering as well as activation","volume":"40","author":"Martin","year":"2007","journal-title":"Bone"},{"issue":"1","key":"10.1016\/j.mcna.2008.09.006_bib9","doi-asserted-by":"crossref","first-page":"507","DOI":"10.4049\/jimmunol.169.1.507","article-title":"Inhibition of endogenous TGF-beta during experimental osteoarthritis prevents osteophyte formation and impairs cartilage repair","volume":"169","author":"Scharstuhl","year":"2002","journal-title":"J Immunol"},{"issue":"12","key":"10.1016\/j.mcna.2008.09.006_bib10","doi-asserted-by":"crossref","first-page":"3442","DOI":"10.1002\/art.11328","article-title":"Reduction of osteophyte formation and synovial thickening by adenoviral overexpression of transforming growth factor beta\/bone morphogenetic protein inhibitors during experimental osteoarthritis","volume":"48","author":"Scharstuhl","year":"2003","journal-title":"Arthritis Rheum"},{"issue":"3","key":"10.1016\/j.mcna.2008.09.006_bib11","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/j.joca.2006.11.006","article-title":"Osteophytes: relevance and biology","volume":"15","author":"van der Kraan","year":"2007","journal-title":"Osteoarthr Cartil"},{"issue":"2","key":"10.1016\/j.mcna.2008.09.006_bib12","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/j.joca.2006.06.020","article-title":"Osteophytes, juxta-articular radiolucencies and cancellous bone changes in the proximal tibia of patients with knee osteoarthritis","volume":"15","author":"Messent","year":"2007","journal-title":"Osteoarthr Cartil"},{"issue":"3","key":"10.1016\/j.mcna.2008.09.006_bib13","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1016\/j.bone.2005.08.020","article-title":"Role of endochondral ossification of articular cartilage and functional adaptation of the subchondral plate in the development of fatigue microcracking of joints","volume":"38","author":"Muir","year":"2006","journal-title":"Bone"},{"issue":"6","key":"10.1016\/j.mcna.2008.09.006_bib14","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1053\/joca.1999.0268","article-title":"Advancement in the zone of calcified cartilage in osteoarthritic hands of patients detected by high definition macroradiography","volume":"7","author":"Patel","year":"1999","journal-title":"Osteoarthr Cartil"},{"issue":"3","key":"10.1016\/j.mcna.2008.09.006_bib15","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1302\/0301-620X.59B3.893504","article-title":"The vascularity and remodelling of subchondrial bone and calcified cartilage in adult human femoral and humeral heads. An age- and stress-related phenomenon","volume":"59","author":"Lane","year":"1977","journal-title":"J Bone Joint Surg Br"},{"issue":"5","key":"10.1016\/j.mcna.2008.09.006_bib16","doi-asserted-by":"crossref","first-page":"914","DOI":"10.1016\/S0736-0266(01)00012-2","article-title":"A decreased subchondral trabecular bone tissue elastic modulus is associated with pre-arthritic cartilage damage","volume":"19","author":"Day","year":"2001","journal-title":"J\u00a0Orthop Res"},{"key":"10.1016\/j.mcna.2008.09.006_bib17","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1097\/01.blo.0000200241.14684.4e","article-title":"Mineral changes in osteoporosis: a review","volume":"443","author":"Faibish","year":"2006","journal-title":"Clin Orthop Relat Res"},{"issue":"5","key":"10.1016\/j.mcna.2008.09.006_bib18","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/S8756-3282(97)00170-1","article-title":"Bonse mineral density reflects bone mass but also the degree of mineralization of bone: therapeutic implications","volume":"21","author":"Meunier","year":"1997","journal-title":"Bone"},{"issue":"4","key":"10.1016\/j.mcna.2008.09.006_bib19","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1136\/ard.56.4.247","article-title":"Mechanical and material properties of the subchondral bone plate from the femoral head of patients with osteoarthritis or osteoporosis","volume":"56","author":"Li","year":"1997","journal-title":"Ann Rheum Dis"},{"issue":"3\u20134","key":"10.1016\/j.mcna.2008.09.006_bib20","first-page":"359","article-title":"Adaptation of subchondral bone in osteoarthritis","volume":"41","author":"Day","year":"2004","journal-title":"Biorheology"},{"issue":"12","key":"10.1016\/j.mcna.2008.09.006_bib21","doi-asserted-by":"crossref","first-page":"1302","DOI":"10.1016\/j.joca.2006.07.012","article-title":"Differences in trabecular structure between knees with and without osteoarthritis quantified by macro and standard radiography, respectively","volume":"14","author":"Messent","year":"2006","journal-title":"Osteoarthr Cartil"},{"key":"10.1016\/j.mcna.2008.09.006_bib22","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1097\/00003086-198612000-00005","article-title":"Role of subchondral bone in the initiation and progression of cartilage damage","volume":"213","author":"Radin","year":"1986","journal-title":"Clin Orthop Relat Res"},{"issue":"Suppl","key":"10.1016\/j.mcna.2008.09.006_bib23","doi-asserted-by":"crossref","first-page":"S27","DOI":"10.1097\/01.blo.0000144854.66565.8f","article-title":"The role of cytokines in cartilage matrix degeneration in osteoarthritis","volume":"427","author":"Goldring","year":"2004","journal-title":"Clin Orthop"},{"issue":"6","key":"10.1016\/j.mcna.2008.09.006_bib24","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1053\/joca.2002.0801","article-title":"Articular cartilage repair: basic science and clinical progress. A review of the current status and prospects","volume":"10","author":"Hunziker","year":"2002","journal-title":"Osteoarthr Cartil"},{"issue":"1","key":"10.1016\/j.mcna.2008.09.006_bib25","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1006\/abbi.1997.0492","article-title":"Aggrecan turnover in human articular cartilage: use of aspartic acid racemization as a marker of molecular age","volume":"350","author":"Maroudas","year":"1998","journal-title":"Arch Biochem Biophys"},{"issue":"7","key":"10.1016\/j.mcna.2008.09.006_bib26","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1016\/j.joca.2006.12.008","article-title":"Aggrecanolysis in human osteoarthritis: confocal localization and biochemical characterization of ADAMTS5-hyaluronan complexes in articular cartilages","volume":"15","author":"Plaas","year":"2007","journal-title":"Osteoarthr Cartil"},{"issue":"2","key":"10.1016\/j.mcna.2008.09.006_bib27","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1186\/ar148","article-title":"Articular cartilage and changes in arthritis. An introduction: cell biology of osteoarthritis","volume":"3","author":"Sandell","year":"2001","journal-title":"Arthritis Res"},{"issue":"3","key":"10.1016\/j.mcna.2008.09.006_bib28","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1002\/jcp.21258","article-title":"Osteoarthritis","volume":"213","author":"Goldring","year":"2007","journal-title":"J Cell Physiol"},{"key":"10.1016\/j.mcna.2008.09.006_bib29","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.1016\/j.joca.2008.02.011","article-title":"Dual proline labeling protocol for individual \u201cbaseline\u201d and \u201cresponse\u201d biosynthesis measurements in human articular cartilage","volume":"16","author":"Goodwin","year":"2008","journal-title":"Osteoarthr Cartil"},{"issue":"1","key":"10.1016\/j.mcna.2008.09.006_bib30","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1007\/BF00177678","article-title":"Technetium 99m methylene diphosphonate bone scanning in osteoarthritic hands","volume":"18","author":"Buckland-Wright","year":"1991","journal-title":"Eur J Nucl Med"},{"issue":"8","key":"10.1016\/j.mcna.2008.09.006_bib31","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1136\/ard.45.8.617","article-title":"99mTc HMDP bone scanning in generalised nodal osteoarthritis. I. Comparison of the standard radiograph and four hour bone scan image of the hand","volume":"45","author":"Hutton","year":"1986","journal-title":"Ann Rheum Dis"},{"issue":"8","key":"10.1016\/j.mcna.2008.09.006_bib32","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1136\/ard.45.8.622","article-title":"99mTc HMDP bone scanning in generalised nodal osteoarthritis. II. The four hour bone scan image predicts radiographic change","volume":"45","author":"Hutton","year":"1986","journal-title":"Ann Rheum Dis"},{"issue":"9","key":"10.1016\/j.mcna.2008.09.006_bib33","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1136\/ard.50.9.623","article-title":"Comparison of clinical, radionuclide, and radiographic features of osteoarthritis of the hands","volume":"50","author":"Macfarlane","year":"1991","journal-title":"Ann Rheum Dis"},{"issue":"8","key":"10.1016\/j.mcna.2008.09.006_bib34","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1136\/ard.52.8.557","article-title":"Prediction of the progression of joint space narrowing in osteoarthritis of the knee by bone scintigraphy","volume":"52","author":"Dieppe","year":"1993","journal-title":"Ann Rheum Dis"},{"issue":"8","key":"10.1016\/j.mcna.2008.09.006_bib35","doi-asserted-by":"crossref","first-page":"938","DOI":"10.1136\/ard.51.8.938","article-title":"Scintigraphic assessment of osteoarthritis of the knee joint","volume":"51","author":"McCrae","year":"1992","journal-title":"Ann Rheum Dis"},{"issue":"8","key":"10.1016\/j.mcna.2008.09.006_bib36","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1136\/ard.59.8.641","article-title":"Early radiographic features in patients with anterior cruciate ligament rupture","volume":"59","author":"Buckland-Wright","year":"2000","journal-title":"Ann Rheum Dis"},{"issue":"10","key":"10.1016\/j.mcna.2008.09.006_bib37","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1136\/ard.55.10.749","article-title":"Fractal signature analysis measures cancellous bone organisation in macroradiographs of patients with knee osteoarthritis","volume":"55","author":"Buckland-Wright","year":"1996","journal-title":"Ann Rheum Dis"},{"issue":"9","key":"10.1016\/j.mcna.2008.09.006_bib38","first-page":"1734","article-title":"Quantitative microfocal radiographic assessment of osteoarthritis of the knee from weight bearing tunnel and semiflexed standing views","volume":"21","author":"Buckland-Wright","year":"1994","journal-title":"J Rheumatol"},{"issue":"5","key":"10.1016\/j.mcna.2008.09.006_bib39","first-page":"788","article-title":"Relationship between joint space width and subchondral sclerosis in the osteoarthritic hand: a quantitative microfocal radiographic study","volume":"19","author":"Buckland-Wright","year":"1992","journal-title":"J Rheumatol"},{"issue":"11","key":"10.1016\/j.mcna.2008.09.006_bib40","doi-asserted-by":"crossref","first-page":"3494","DOI":"10.1002\/art.22160","volume":"54","author":"Bingham","year":"2006","journal-title":"Arthritis Rheum"},{"issue":"2","key":"10.1016\/j.mcna.2008.09.006_bib41","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1093\/rheumatology\/kel213","article-title":"A 2 yr longitudinal radiographic study examining the effect of a bisphosphonate (risedronate) upon subchondral bone loss in osteoarthritic knee patients","volume":"46","author":"Buckland-Wright","year":"2007","journal-title":"Rheumatology (Oxford)"},{"issue":"11","key":"10.1016\/j.mcna.2008.09.006_bib42","first-page":"2187","article-title":"Periarticular osteoporosis in osteoarthritis of the knee","volume":"25","author":"Karvonen","year":"1998","journal-title":"J Rheumatol"},{"issue":"6","key":"10.1016\/j.mcna.2008.09.006_bib43","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1007\/s00223-004-0160-7","article-title":"Fractal analysis of trabecular bone in knee osteoarthritis (OA) is a more sensitive marker of disease status than bone mineral density (BMD)","volume":"76","author":"Messent","year":"2005","journal-title":"Calcif Tissue Int"},{"issue":"1","key":"10.1016\/j.mcna.2008.09.006_bib44","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.joca.2004.10.009","article-title":"Cancellous bone differences between knees with early, definite and advanced joint space loss; a comparative quantitative macroradiographic study","volume":"13","author":"Messent","year":"2005","journal-title":"Osteoarthr Cartil"},{"issue":"6","key":"10.1016\/j.mcna.2008.09.006_bib45","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1016\/j.joca.2005.01.007","article-title":"Tibial cancellous bone changes in patients with knee osteoarthritis. A short-term longitudinal study using Fractal Signature Analysis","volume":"13","author":"Messent","year":"2005","journal-title":"Osteoarthr Cartil"},{"issue":"Suppl","key":"10.1016\/j.mcna.2008.09.006_bib46","doi-asserted-by":"crossref","first-page":"S138","DOI":"10.1097\/01.blo.0000143838.53434.b8","article-title":"Functional genomics of osteoarthritis: on the way to evaluate disease hypotheses","volume":"427","author":"Aigner","year":"2004","journal-title":"Clin Orthop Relat Res"},{"issue":"11","key":"10.1016\/j.mcna.2008.09.006_bib47","doi-asserted-by":"crossref","first-page":"3533","DOI":"10.1002\/art.22174","article-title":"Large-scale gene expression profiling reveals major pathogenetic pathways of cartilage degeneration in osteoarthritis","volume":"54","author":"Aigner","year":"2006","journal-title":"Arthritis Rheum"},{"issue":"3","key":"10.1016\/j.mcna.2008.09.006_bib48","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1148\/radiology.167.3.3363136","article-title":"Transient osteoporosis: transient bone marrow edema?","volume":"167","author":"Wilson","year":"1988","journal-title":"Radiology"},{"issue":"9","key":"10.1016\/j.mcna.2008.09.006_bib49","doi-asserted-by":"crossref","first-page":"2986","DOI":"10.1002\/art.22851","article-title":"Correlation of the development of knee pain with enlarging bone marrow lesions on magnetic resonance imaging","volume":"56","author":"Felson","year":"2007","journal-title":"Arthritis Rheum"},{"issue":"1","key":"10.1016\/j.mcna.2008.09.006_bib50","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1002\/art.23173","article-title":"Central bone marrow lesions in symptomatic knee osteoarthritis and their relationship to anterior cruciate ligament tears and cartilage loss","volume":"58","author":"Hernandez-Molina","year":"2008","journal-title":"Arthritis Rheum"},{"issue":"5","key":"10.1016\/j.mcna.2008.09.006_bib51","doi-asserted-by":"crossref","first-page":"1529","DOI":"10.1002\/art.21789","article-title":"Increase in bone marrow lesions associated with cartilage loss: a longitudinal magnetic resonance imaging study of knee osteoarthritis","volume":"54","author":"Hunter","year":"2006","journal-title":"Arthritis Rheum"},{"issue":"9","key":"10.1016\/j.mcna.2008.09.006_bib52","doi-asserted-by":"crossref","first-page":"2814","DOI":"10.1002\/art.21290","article-title":"Bone marrow lesions in the knee are associated with increased local bone density","volume":"52","author":"Lo","year":"2005","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.mcna.2008.09.006_bib53","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1016\/j.joca.2008.02.001","article-title":"Prevalence of bone attrition on knee radiographs and MRI in a community-based cohort","volume":"16","author":"Reichenbach","year":"2008","journal-title":"Osteoarthr Cartil"},{"issue":"5","key":"10.1016\/j.mcna.2008.09.006_bib54","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1007\/s00256-008-0446-3","article-title":"Bone marrow edema pattern in advanced hip osteoarthritis: quantitative assessment with magnetic resonance imaging and correlation with clinical examination, radiographic findings, and histopathology","volume":"37","author":"Taljanovic","year":"2008","journal-title":"Skeletal Radiol"},{"issue":"1","key":"10.1016\/j.mcna.2008.09.006_bib55","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/S0033-8389(03)00165-9","article-title":"Cysts, geodes, and erosions","volume":"42","author":"Bancroft","year":"2004","journal-title":"Radiol Clin North Am"},{"issue":"10","key":"10.1016\/j.mcna.2008.09.006_bib56","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1016\/j.joca.2006.05.011","article-title":"MRI of bone marrow edema-like signal in the pathogenesis of subchondral cysts","volume":"14","author":"Carrino","year":"2006","journal-title":"Osteoarthr Cartil"},{"issue":"2","key":"10.1016\/j.mcna.2008.09.006_bib57","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1302\/0301-620X.75B2.8444939","article-title":"Bone-marrow oedema syndrome and transient osteoporosis of the hip. An MRI-controlled study of treatment by core decompression","volume":"75","author":"Hofmann","year":"1993","journal-title":"J Bone Joint Surg Br"},{"issue":"3","key":"10.1016\/j.mcna.2008.09.006_bib58","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1148\/radiology.215.3.r00jn05835","article-title":"Bone marrow edema pattern in osteoarthritic knees: correlation between MR imaging and histologic findings","volume":"215","author":"Zanetti","year":"2000","journal-title":"Radiology"},{"issue":"Pt 3","key":"10.1016\/j.mcna.2008.09.006_bib59","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1046\/j.1469-7580.2003.00158.x","article-title":"Expression of bone morphogenetic proteins and cartilage-derived morphogenetic proteins during osteophyte formation in humans","volume":"202","author":"Zoricic","year":"2003","journal-title":"J Anat"},{"issue":"6","key":"10.1016\/j.mcna.2008.09.006_bib60","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1016\/j.joca.2007.02.005","article-title":"TGF-beta and osteoarthritis","volume":"15","author":"Blaney Davidson","year":"2007","journal-title":"Osteoarthr Cartil"},{"issue":"5","key":"10.1016\/j.mcna.2008.09.006_bib61","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1053\/joca.1998.0129","article-title":"Differential effects of local application of BMP-2 or TGF-beta 1 on both articular cartilage composition and osteophyte formation","volume":"6","author":"van Beuningen","year":"1998","journal-title":"Osteoarthr Cartil"},{"issue":"1","key":"10.1016\/j.mcna.2008.09.006_bib62","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1053\/joca.1999.0267","article-title":"Osteoarthritis-like changes in the murine knee joint resulting from intra-articular transforming growth factor-beta injections","volume":"8","author":"van Beuningen","year":"2000","journal-title":"Osteoarthr Cartil"},{"issue":"2","key":"10.1016\/j.mcna.2008.09.006_bib63","first-page":"279","article-title":"Transforming growth factor-beta 1 stimulates articular chondrocyte proteoglycan synthesis and induces osteophyte formation in the murine knee joint","volume":"71","author":"van Beuningen","year":"1994","journal-title":"Lab Invest"},{"issue":"6","key":"10.1016\/j.mcna.2008.09.006_bib64","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1002\/art.1780330612","article-title":"The effect of marginal osteophytes on reduction of varus-valgus instability in osteoarthritic knees","volume":"33","author":"Pottenger","year":"1990","journal-title":"Arthritis Rheum"}],"container-title":["Medical Clinics of North America"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S002571250800134X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S002571250800134X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,5,22]],"date-time":"2023-05-22T10:35:17Z","timestamp":1684751717000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S002571250800134X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,1]]},"references-count":64,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2009,1]]}},"alternative-id":["S002571250800134X"],"URL":"https:\/\/doi.org\/10.1016\/j.mcna.2008.09.006","relation":{},"ISSN":["0025-7125"],"issn-type":[{"value":"0025-7125","type":"print"}],"subject":[],"published":{"date-parts":[[2009,1]]}}}