{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T01:04:16Z","timestamp":1772759056894,"version":"3.50.1"},"reference-count":67,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2011,11,1]],"date-time":"2011-11-01T00:00:00Z","timestamp":1320105600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medical Clinics of North America"],"published-print":{"date-parts":[[2011,11]]},"DOI":"10.1016\/j.mcna.2011.08.007","type":"journal-article","created":{"date-parts":[[2011,10,8]],"date-time":"2011-10-08T04:10:29Z","timestamp":1318047029000},"page":"1143-1161","source":"Crossref","is-referenced-by-count":59,"title":["Community-Acquired Pneumonia: An Unfinished Battle"],"prefix":"10.1016","volume":"95","author":[{"given":"Girish B.","family":"Nair","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael S.","family":"Niederman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.mcna.2011.08.007_bib1","doi-asserted-by":"crossref","first-page":"S2","DOI":"10.1086\/511159","article-title":"Infectious Diseases Society of America\/American Thoracic Society consensus guidelines on the management of community-acquired pneumonia in adults","volume":"44","author":"Mandell","year":"2007","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.mcna.2011.08.007_bib2","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1177\/1753465810381518","article-title":"Management of community-acquired pneumonia: a review and update","volume":"5","author":"Brar","year":"2011","journal-title":"Ther Adv Respir Dis"},{"key":"10.1016\/j.mcna.2011.08.007_bib3","unstructured":"Kochanek KD, Xu J, Murphy SL, et\u00a0al. Deaths: Preliminary data for 2009. National Vital Statistics Reports 59, No. 4.CDC 2011. Available at: http:\/\/www.cdc.gov\/nchs\/data\/nvsr\/nvsr59\/nvsr59_04.pdf. Accessed 30, June 2011."},{"key":"10.1016\/j.mcna.2011.08.007_bib4","unstructured":"Heron MP, Hoyert DL, Murphy SL, et\u00a0al. Deaths: Final data for 2006. National Vital Statistics Reports 57. National Center for Health Statistics2009. Available at: http:\/\/www.cdc.gov\/nchs\/fastats\/pneumonia.htm. Accessed 10, July 2011."},{"key":"10.1016\/j.mcna.2011.08.007_bib5","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1001\/jama.275.2.134","article-title":"Prognosis and outcomes of patients with community-acquired pneumonia. A meta-analysis","volume":"275","author":"Fine","year":"1996","journal-title":"JAMA"},{"key":"10.1016\/j.mcna.2011.08.007_bib6","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1055\/s-0029-1202941","article-title":"Global and local epidemiology of community-acquired pneumonia: the experience of the CAPNETZ network","volume":"30","author":"Welte","year":"2009","journal-title":"Semin Respir Crit Care Med"},{"key":"10.1016\/j.mcna.2011.08.007_bib7","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1001\/archinte.163.3.317","article-title":"Pneumonia: still the old man\u2019s friend?","volume":"163","author":"Kaplan","year":"2003","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.mcna.2011.08.007_bib8","doi-asserted-by":"crossref","first-page":"130","DOI":"10.3810\/pgm.2010.03.2130","article-title":"Burden of community-acquired pneumonia in North American adults","volume":"122","author":"File","year":"2010","journal-title":"Postgrad Med"},{"key":"10.1016\/j.mcna.2011.08.007_bib9","first-page":"719","article-title":"Economic benefit of a 1-day reduction in hospital stay for community-acquired pneumonia (CAP)","volume":"13","author":"Kozma","year":"2010","journal-title":"J\u00a0Med Econ"},{"key":"10.1016\/j.mcna.2011.08.007_bib10","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1183\/09031936.06.00062505","article-title":"Validation of a predictive rule for the management of community-acquired pneumonia","volume":"27","author":"Capelastegui","year":"2006","journal-title":"Eur Respir J"},{"key":"10.1016\/j.mcna.2011.08.007_bib11","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1016\/j.amjmed.2005.01.006","article-title":"Prospective comparison of three validated prediction rules for prognosis in community-acquired pneumonia","volume":"118","author":"Aujesky","year":"2005","journal-title":"Am J Med"},{"key":"10.1016\/j.mcna.2011.08.007_bib12","doi-asserted-by":"crossref","first-page":"S127","DOI":"10.1086\/591393","article-title":"Biological markers to determine eligibility in trials for community-acquired pneumonia: a focus on procalcitonin","volume":"47","author":"Niederman","year":"2008","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.mcna.2011.08.007_bib13","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1016\/j.idc.2004.07.004","article-title":"Community-acquired pneumonia: pathophysiology and host factors with focus on possible new approaches to management of lower respiratory tract infections","volume":"18","author":"Wunderink","year":"2004","journal-title":"Infect Dis Clin North Am"},{"key":"10.1016\/j.mcna.2011.08.007_bib14","doi-asserted-by":"crossref","first-page":"391","DOI":"10.7326\/0003-4819-149-6-200809160-00005","article-title":"Proton-pump inhibitor use and the risk for community-acquired pneumonia","volume":"149","author":"Sarkar","year":"2008","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.mcna.2011.08.007_bib15","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1586\/ers.10.13","article-title":"Genetic risk of acute pulmonary infections and sepsis","volume":"4","author":"Waterer","year":"2010","journal-title":"Expert Rev Respir Med"},{"key":"10.1016\/j.mcna.2011.08.007_bib16","doi-asserted-by":"crossref","first-page":"2030","DOI":"10.1097\/00003246-199909000-00056","article-title":"Inflammation in severe pneumonia: act locally, not globally","volume":"27","author":"Niederman","year":"1999","journal-title":"Crit Care Med"},{"key":"10.1016\/j.mcna.2011.08.007_bib17","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/S0272-5231(05)70230-6","article-title":"Atypical pathogens in community-acquired pneumonia","volume":"20","author":"Lieberman","year":"1999","journal-title":"Clin Chest Med"},{"key":"10.1016\/j.mcna.2011.08.007_bib18","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1183\/09031936.04.00119503","article-title":"Severe community-acquired pneumonia: assessment of microbial aetiology as mortality factor","volume":"24","author":"Paganin","year":"2004","journal-title":"Eur Respir J"},{"key":"10.1016\/j.mcna.2011.08.007_bib19","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1007\/s10096-008-0485-7","article-title":"Asian Network for Surveillance of Resistant Pathogens (ANSORP) Study Group. Clinical outcomes and risk factors of community-acquired pneumonia caused by gram-negative bacilli","volume":"27","author":"Kang","year":"2008","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"10.1016\/j.mcna.2011.08.007_bib20","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1186\/1471-2334-11-120","article-title":"Severe community-acquired Enterobacter pneumonia: a plea for greater awareness of the concept of health-care-associated pneumonia","volume":"11","author":"Boyer","year":"2011","journal-title":"BMC Infect Dis"},{"key":"10.1016\/j.mcna.2011.08.007_bib21","doi-asserted-by":"crossref","first-page":"1849","DOI":"10.1001\/archinte.162.16.1849","article-title":"Community-acquired pneumonia due to gram-negative bacteria and Pseudomonas aeruginosa: incidence, risk, and prognosis","volume":"162","author":"Arancibia","year":"2002","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.mcna.2011.08.007_bib22","doi-asserted-by":"crossref","first-page":"1343","DOI":"10.1378\/chest.125.4.1343","article-title":"Viral community-acquired pneumonia in non immunocompromised adults","volume":"125","author":"de Roux","year":"2004","journal-title":"Chest"},{"key":"10.1016\/j.mcna.2011.08.007_bib23","doi-asserted-by":"crossref","DOI":"10.7326\/0003-4819-151-7-200910060-01004","article-title":"In the clinic - community-acquired pneumonia","volume":"151","author":"Niederman","year":"2009","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.mcna.2011.08.007_bib24","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1378\/chest.09-1562","article-title":"Expanded clinical presentation of community-acquired methicillin-resistant Staphylococcus aureus pneumonia","volume":"138","author":"Lobo","year":"2010","journal-title":"Chest"},{"key":"10.1016\/j.mcna.2011.08.007_bib25","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1086\/427148","article-title":"Severe community-onset pneumonia in healthy adults caused by methicillin-resistant Staphylococcus aureus carrying the Panton-Valentine leukocidin genes","volume":"40","author":"Francis","year":"2005","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.mcna.2011.08.007_bib26","doi-asserted-by":"crossref","first-page":"249","DOI":"10.7326\/0003-4819-148-4-200802190-00204","article-title":"Emergence of multidrug-resistant, community associated, methicillin-resistant Staphylococcus aureus clone USA300 in men who have sex with men","volume":"148","author":"Diep","year":"2008","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.mcna.2011.08.007_bib27","series-title":"Murray and Nadel\u2019s Textbook of Respiratory Medicine. [Chapter: Pyogenic Bacterial Pneumonia and Lung Abscess] vol. 1","first-page":"699","article-title":"Infectious disease of lung","author":"Torres","year":"2010"},{"key":"10.1016\/j.mcna.2011.08.007_bib28","doi-asserted-by":"crossref","first-page":"1440","DOI":"10.1001\/jama.278.17.1440","article-title":"Does this patient have community-acquired pneumonia? Diagnosing pneumonia by history and physical examination","volume":"278","author":"Metlay","year":"1997","journal-title":"JAMA"},{"key":"10.1016\/j.mcna.2011.08.007_bib29","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1086\/313959","article-title":"Canadian guidelines for the initial management of community-acquired pneumonia: an evidence-based update by the Canadian Infectious Diseases Society and the Canadian Thoracic Society","volume":"31","author":"Mandell","year":"2000","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.mcna.2011.08.007_bib30","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1136\/thx.2004.030411","article-title":"Comparison between pathogen directed antibiotic treatment and empirical broad spectrum antibiotic treatment in patients with community acquired pneumonia: a prospective randomised study","volume":"60","author":"van der Eerden","year":"2005","journal-title":"Thorax"},{"key":"10.1016\/j.mcna.2011.08.007_bib31","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1007\/s10096-005-1316-8","article-title":"Value of intensive diagnostic microbiological investigation in low- and high-risk patients with community-acquired pneumonia","volume":"24","author":"van der Eerden","year":"2005","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"10.1016\/j.mcna.2011.08.007_bib32","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1378\/chest.09-0998","article-title":"Thrombocytopenia and thrombocytosis at time of hospitalization predict mortality in patients with community-acquired pneumonia","volume":"137","author":"Mirsaeidi","year":"2010","journal-title":"Chest"},{"key":"10.1016\/j.mcna.2011.08.007_bib33","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1159\/000100866","article-title":"Hyponatremia in community-acquired pneumonia","volume":"27","author":"Nair","year":"2007","journal-title":"Am J Nephrol"},{"key":"10.1016\/j.mcna.2011.08.007_bib34","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1016\/j.crad.2004.01.011","article-title":"Inter-observer variation in the interpretation of chest radiographs for pneumonia in community-acquired lower respiratory tract infections","volume":"59","author":"Hopstaken","year":"2004","journal-title":"Clin Radiol"},{"key":"10.1016\/j.mcna.2011.08.007_bib35","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1086\/514675","article-title":"High-resolution computed tomography for the diagnosis of community-acquired pneumonia","volume":"27","author":"Syrj\u00e4l\u00e4","year":"1998","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.mcna.2011.08.007_bib36","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1164\/rccm.200309-1248OC","article-title":"Predicting bacteremia in patients with community-acquired pneumonia","volume":"169","author":"Metersky","year":"2004","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.mcna.2011.08.007_bib37","doi-asserted-by":"crossref","first-page":"2810","DOI":"10.1128\/JCM.41.7.2810-2813.2003","article-title":"Rapid diagnosis of bacteremic pneumococcal infections in adults by using the Binax NOW Streptococcus pneumoniae urinary antigen test: a prospective, controlled clinical evaluation","volume":"41","author":"Smith","year":"2003","journal-title":"J\u00a0Clin Microbiol"},{"key":"10.1016\/j.mcna.2011.08.007_bib38","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1080\/00365540510027174","article-title":"Utility of a pneumonia severity index in the optimization of the diagnostic and therapeutic effort for community-acquired pneumonia","volume":"37","author":"Ortega","year":"2005","journal-title":"Scand J Infect Dis"},{"key":"10.1016\/j.mcna.2011.08.007_bib39","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1086\/342903","article-title":"Trends in legionnaire\u2019s disease, 1980-1998: declining mortality and new patterns of diagnosis","volume":"35","author":"Benin","year":"2002","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.mcna.2011.08.007_bib40","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1001\/archinternmed.2010.347","article-title":"Current and potential usefulness of pneumococcal urinary antigen detection in hospitalized patients with community-acquired pneumonia to guide antimicrobial therapy","volume":"171","author":"Sord\u00e9","year":"2011","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.mcna.2011.08.007_bib41","doi-asserted-by":"crossref","first-page":"1426","DOI":"10.1164\/rccm.201003-0415OC","article-title":"Cardiovascular and inflammatory biomarkers to predict short- and long-term survival in community-acquired pneumonia: results from the German Competence Network, CAPNETZ","volume":"182","author":"Kr\u00fcger","year":"2010","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.mcna.2011.08.007_bib42","doi-asserted-by":"crossref","DOI":"10.1097\/CCM.0b013e3182257445","article-title":"Inflammatory biomarkers and prediction for intensive care unit admission in severe community-acquired pneumonia","author":"Ram\u00edrez","year":"2011","journal-title":"Crit Care Med"},{"key":"10.1016\/j.mcna.2011.08.007_bib43","doi-asserted-by":"crossref","first-page":"1335","DOI":"10.1378\/chest.125.4.1335","article-title":"Contribution of C-reactive protein to the diagnosis and assessment of severity of community-acquired pneumonia","volume":"125","author":"Almirall","year":"2004","journal-title":"Chest"},{"key":"10.1016\/j.mcna.2011.08.007_bib44","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1183\/09031936.00035610","article-title":"Procalcitonin-Guided Antibiotic Therapy and Hospitalisation in Patients with Lower Respiratory Tract Infections (ProHOSP) Study Group. Prognostic value of procalcitonin in community-acquired pneumonia","volume":"37","author":"Schuetz","year":"2011","journal-title":"Eur Respir J"},{"key":"10.1016\/j.mcna.2011.08.007_bib45","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1378\/chest.09-2920","article-title":"Procalcitonin levels predict bacteremia in patients with community-acquired pneumonia: a prospective cohort trial","volume":"138","author":"M\u00fcller","year":"2010","journal-title":"Chest"},{"key":"10.1016\/j.mcna.2011.08.007_bib46","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1164\/rccm.200512-1922OC","article-title":"Procalcitonin guidance of antibiotic therapy in community- acquired pneumonia: a randomized trial","volume":"174","author":"Christ-Crain","year":"2006","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.mcna.2011.08.007_bib47","doi-asserted-by":"crossref","first-page":"2867","DOI":"10.1097\/CCM.0b013e3181b02dbb","article-title":"Association between timing of intensive care unit admission and outcomes for emergency department patients with community acquired pneumonia","volume":"37","author":"Renaud","year":"2009","journal-title":"Crit Care Med"},{"key":"10.1016\/j.mcna.2011.08.007_bib48","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1378\/chest.09-1547","article-title":"Late admission to the ICU in patients with community-acquired pneumonia is associated with higher mortality","volume":"137","author":"Restrepo","year":"2010","journal-title":"Chest"},{"key":"10.1016\/j.mcna.2011.08.007_bib49","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1086\/644741","article-title":"Reasons why emergency department providers do not rely on the Pneumonia Severity Index to determine the initial site of treatment for patients with pneumonia","volume":"49","author":"Aujesky","year":"2009","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.mcna.2011.08.007_bib50","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1056\/NEJM199701233360402","article-title":"A\u00a0prediction rule to identify low-risk patients with community-acquired pneumonia","volume":"336","author":"Fine","year":"1997","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.mcna.2011.08.007_bib51","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1378\/chest.07-0306","article-title":"Pneumonia severity index class V patients with community-acquired pneumonia: characteristics, outcomes, and value of severity","volume":"132","author":"Valencia","year":"2007","journal-title":"Chest"},{"key":"10.1016\/j.mcna.2011.08.007_bib52","doi-asserted-by":"crossref","first-page":"944","DOI":"10.1136\/thx.2010.138131","article-title":"Predicting mortality in the elderly with community-acquired pneumonia: should we design a new car or set a new \u2019speed limit\u2019?","volume":"65","author":"Brito","year":"2010","journal-title":"Thorax"},{"key":"10.1016\/j.mcna.2011.08.007_bib53","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1111\/j.1365-2796.2006.01657.x","article-title":"CRB-65 predicts death from community-acquired pneumonia","volume":"260","author":"Bauer","year":"2006","journal-title":"J\u00a0Intern Med"},{"key":"10.1016\/j.mcna.2011.08.007_bib54","doi-asserted-by":"crossref","first-page":"2509","DOI":"10.1097\/01.CCM.0000287587.43801.9C","article-title":"Effects of delayed oxygenation assessment on time to antibiotic delivery and mortality in patients with severe community-acquired pneumonia","volume":"35","author":"Blot","year":"2007","journal-title":"Crit Care Med"},{"key":"10.1016\/j.mcna.2011.08.007_bib55","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.annemergmed.2008.01.003","article-title":"Risk prediction with procalcitonin and clinical rules in community-acquired pneumonia","volume":"52","author":"Huang","year":"2008","journal-title":"Ann Emerg Med"},{"key":"10.1016\/j.mcna.2011.08.007_bib56","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1183\/09031936.00054507","article-title":"Procalcitonin predicts patients at low risk of death from community acquired pneumonia across all CRB-65 classes","volume":"31","author":"Kruger","year":"2008","journal-title":"Eur Respir J"},{"key":"10.1016\/j.mcna.2011.08.007_bib57","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1086\/596307","article-title":"Severe community-acquired pneumonia: validation of the Infectious Diseases Society of America\/American Thoracic Society guidelines to predict an intensive care unit admission","volume":"48","author":"Liapikou","year":"2009","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.mcna.2011.08.007_bib58","doi-asserted-by":"crossref","first-page":"3010","DOI":"10.1097\/CCM.0b013e3181b030d9","article-title":"Validation of the Infectious Disease Society of America\/American Thoracic Society 2007 guidelines for severe community-acquired pneumonia","volume":"37","author":"Brown","year":"2009","journal-title":"Crit Care Med"},{"key":"10.1016\/j.mcna.2011.08.007_bib59","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1097\/CCM.0b013e318194b021","article-title":"PIRO score for community-acquired pneumonia: a new prediction rule for assessment of severity in intensive care unit patients with community-acquired pneumonia","volume":"37","author":"Rello","year":"2009","journal-title":"Crit Care Med"},{"key":"10.1016\/j.mcna.2011.08.007_bib60","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1086\/589754","article-title":"SMART-COP: a tool for predicting the need for intensive respiratory or vasopressor support in community-acquired pneumonia","volume":"47","author":"Charles","year":"2008","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.mcna.2011.08.007_bib61","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1001\/archinte.164.6.637","article-title":"Timing of antibiotic administration and outcomes for Medicare patients hospitalized with community-acquired pneumonia","volume":"164","author":"Houck","year":"2004","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.mcna.2011.08.007_bib62","doi-asserted-by":"crossref","first-page":"2080","DOI":"10.1001\/jama.278.23.2080","article-title":"Quality of care, process, and outcomes in elderly patients with pneumonia","volume":"278","author":"Meehan","year":"1997","journal-title":"JAMA"},{"key":"10.1016\/j.mcna.2011.08.007_bib63","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1378\/chest.06-1426","article-title":"Antibiotics for bacteremic pneumonia: improved outcomes with macrolides but not fluoroquinolones","volume":"131","author":"Metersky","year":"2007","journal-title":"Chest"},{"key":"10.1016\/j.mcna.2011.08.007_bib64","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1164\/rccm.200311-1578OC","article-title":"Combination antibiotic therapy lowers mortality among severely ill patients with pneumococcal bacteremia","volume":"170","author":"Baddour","year":"2004","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.mcna.2011.08.007_bib65","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1378\/chest.128.1.172","article-title":"Comparison of levofloxacin and cefotaxime combined with ofloxacin for ICU patients with community-acquired pneumonia who do not require vasopressors","volume":"128","author":"Leroy","year":"2005","journal-title":"Chest"},{"key":"10.1016\/j.mcna.2011.08.007_bib66","doi-asserted-by":"crossref","first-page":"1493","DOI":"10.1097\/01.CCM.0000266755.75844.05","article-title":"Combination antibiotic therapy improves survival in patients with community-acquired pneumonia and shock","volume":"35","author":"Rodr\u00edguez","year":"2007","journal-title":"Crit Care Med"},{"key":"10.1016\/j.mcna.2011.08.007_bib67","doi-asserted-by":"crossref","first-page":"848","DOI":"10.1001\/archinte.161.6.848","article-title":"Early switch from intravenous to oral antibiotics in hospitalized patients with bacteremic community-acquired Streptococcus pneumoniae pneumonia","volume":"161","author":"Ramirez","year":"2001","journal-title":"Arch Intern Med"}],"container-title":["Medical Clinics of North America"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0025712511000927?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0025712511000927?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,11,29]],"date-time":"2018-11-29T11:50:05Z","timestamp":1543492205000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0025712511000927"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,11]]},"references-count":67,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2011,11]]}},"alternative-id":["S0025712511000927"],"URL":"https:\/\/doi.org\/10.1016\/j.mcna.2011.08.007","relation":{},"ISSN":["0025-7125"],"issn-type":[{"value":"0025-7125","type":"print"}],"subject":[],"published":{"date-parts":[[2011,11]]}}}