{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T02:54:11Z","timestamp":1790391251915,"version":"4.1.0"},"reference-count":39,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2020,5,1]],"date-time":"2020-05-01T00:00:00Z","timestamp":1588291200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,5,1]],"date-time":"2020-05-01T00:00:00Z","timestamp":1588291200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","theclinics.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Medical Clinics of North America"],"published-print":{"date-parts":[[2020,5]]},"DOI":"10.1016\/j.mcna.2020.01.004","type":"journal-article","created":{"date-parts":[[2020,4,17]],"date-time":"2020-04-17T18:32:49Z","timestamp":1587148369000},"page":"471-489","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":17,"title":["Cannabis for Symptom Management in Older Adults"],"prefix":"10.1016","volume":"104","author":[{"given":"Cari","family":"Levy","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily","family":"Galenbeck","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kate","family":"Magid","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.mcna.2020.01.004_bib3","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.jamda.2018.11.013","article-title":"Medical cannabis in the skilled nursing facility: a novel approach to improving symptom management and quality of life","volume":"20","author":"Palace","year":"2019","journal-title":"J\u00a0Am Med Dir Assoc"},{"key":"10.1016\/j.mcna.2020.01.004_bib4","series-title":"National survey on drug use and health: summary of national findings, 2014(NSDUH Series H-48, HHS Publication No. (SMA) 14-4863)","author":"Substance Abuse and Mental Health Services Administration","year":"2013"},{"key":"10.1016\/j.mcna.2020.01.004_bib5","doi-asserted-by":"crossref","DOI":"10.1177\/2333721418781668","article-title":"Marijuana use among adults 50 years or older in the 21st century","volume":"4","author":"Lloyd","year":"2018","journal-title":"Gerontol Geriatr Med"},{"key":"10.1016\/j.mcna.2020.01.004_bib6","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.drugalcdep.2016.11.031","article-title":"Trends and correlates of marijuana use among late middle-aged and older adults in the United States, 2002-2014","volume":"171","author":"Salas-Wright","year":"2017","journal-title":"Drug Alcohol Depend"},{"key":"10.1016\/j.mcna.2020.01.004_bib7","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1016\/j.drugalcdep.2018.07.006","article-title":"Marijuana use by middle-aged and older adults in the United States, 2015-2016","volume":"191","author":"Han","year":"2018","journal-title":"Drug Alcohol Depend"},{"issue":"8","key":"10.1016\/j.mcna.2020.01.004_bib8","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1001\/jamainternmed.2019.1529","article-title":"Educating physicians about marijuana","volume":"179","author":"Morris","year":"2019","journal-title":"JAMA Intern Med"},{"issue":"1","key":"10.1016\/j.mcna.2020.01.004_bib9","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1177\/1049909115604669","article-title":"Medicinal Cannabis: a survey among health care providers in Washington State","volume":"34","author":"Carlini","year":"2017","journal-title":"Am J Hosp Palliat Care"},{"issue":"10","key":"10.1016\/j.mcna.2020.01.004_bib10","doi-asserted-by":"crossref","first-page":"1208","DOI":"10.1089\/jpm.2018.0535","article-title":"A\u00a0survey of hospice professionals regarding medical cannabis practices","volume":"22","author":"Costantino","year":"2019","journal-title":"J\u00a0Palliat Med"},{"issue":"12","key":"10.1016\/j.mcna.2020.01.004_bib11","doi-asserted-by":"crossref","first-page":"1291","DOI":"10.1089\/jpm.2011.0113","article-title":"Assessment of hospice health professionals' knowledge, views, and experience with medical marijuana","volume":"14","author":"Uritsky","year":"2011","journal-title":"J\u00a0Palliat Med"},{"issue":"14","key":"10.1016\/j.mcna.2020.01.004_bib12","doi-asserted-by":"crossref","first-page":"2587","DOI":"10.1007\/s00213-015-3889-y","article-title":"Safety, pharmacodynamics, and pharmacokinetics of multiple oral doses of delta-9-tetrahydrocannabinol in older persons with dementia","volume":"232","author":"Ahmed","year":"2015","journal-title":"Psychopharmacology"},{"issue":"9","key":"10.1016\/j.mcna.2020.01.004_bib13","doi-asserted-by":"crossref","first-page":"2086","DOI":"10.1093\/annonc\/mdq727","article-title":"Delta-9-tetrahydrocannabinol may palliate altered chemosensory perception in cancer patients: results of a randomized, double-blind, placebo-controlled pilot trial","volume":"22","author":"Brisbois","year":"2011","journal-title":"Ann Oncol"},{"issue":"11","key":"10.1016\/j.mcna.2020.01.004_bib14","doi-asserted-by":"crossref","first-page":"1088","DOI":"10.1177\/0269881114550355","article-title":"Effects of cannabidiol in the treatment of patients with Parkinson's disease: an exploratory double-blind trial","volume":"28","author":"Chagas","year":"2014","journal-title":"J\u00a0Psychopharmacol"},{"issue":"11","key":"10.1016\/j.mcna.2020.01.004_bib15","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.1016\/j.jagp.2019.05.002","article-title":"Randomized placebo-controlled trial of Nabilone for agitation in Alzheimer's disease","volume":"27","author":"Herrmann","year":"2019","journal-title":"Am J Geriatr Psychiatry"},{"issue":"2","key":"10.1016\/j.mcna.2020.01.004_bib16","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1177\/1479972310391283","article-title":"Cannabinoid effects on ventilation and breathlessness: a pilot study of efficacy and safety","volume":"8","author":"Pickering","year":"2011","journal-title":"Chron Respir Dis"},{"issue":"23","key":"10.1016\/j.mcna.2020.01.004_bib17","doi-asserted-by":"crossref","first-page":"2338","DOI":"10.1212\/WNL.0000000000001675","article-title":"Tetrahydrocannabinol for neuropsychiatric symptoms in dementia: a randomized controlled trial","volume":"84","author":"van den Elsen","year":"2015","journal-title":"Neurology"},{"issue":"2","key":"10.1016\/j.mcna.2020.01.004_bib18","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1177\/0269881116665357","article-title":"Effects of tetrahydrocannabinol on balance and gait in patients with dementia: a randomised controlled crossover trial","volume":"31","author":"van den Elsen","year":"2017","journal-title":"J\u00a0Psychopharmacol"},{"issue":"12","key":"10.1016\/j.mcna.2020.01.004_bib19","doi-asserted-by":"crossref","first-page":"1214","DOI":"10.1016\/j.jagp.2015.07.011","article-title":"Tetrahydrocannabinol in behavioral disturbances in dementia: a crossover randomized controlled trial","volume":"23","author":"van den Elsen","year":"2015","journal-title":"Am J Geriatr Psychiatry"},{"issue":"1","key":"10.1016\/j.mcna.2020.01.004_bib20","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1007\/s40266-018-0616-5","article-title":"Medical cannabis for older patients","volume":"36","author":"Minerbi","year":"2019","journal-title":"Drugs Aging"},{"issue":"11","key":"10.1016\/j.mcna.2020.01.004_bib21","doi-asserted-by":"crossref","first-page":"754","DOI":"10.1038\/nrc3829","article-title":"Cancer cachexia: understanding the molecular basis","volume":"14","author":"Argiles","year":"2014","journal-title":"Nat Rev Cancer"},{"issue":"1","key":"10.1016\/j.mcna.2020.01.004_bib22","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/j.jpainsymman.2013.02.016","article-title":"Prevalence of symptoms in older cancer patients receiving palliative care: a systematic review and meta-analysis","volume":"47","author":"Van Lancker","year":"2014","journal-title":"J\u00a0Pain Symptom Manage"},{"issue":"5","key":"10.1016\/j.mcna.2020.01.004_bib23","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1007\/s00482-019-0373-3","article-title":"Efficacy, tolerability and safety of cannabis-based medicines for cancer pain: a systematic review with meta-analysis of randomised controlled trials","volume":"33","author":"Hauser","year":"2019","journal-title":"Schmerz"},{"issue":"2","key":"10.1016\/j.mcna.2020.01.004_bib24","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1002\/jcsm.12273","article-title":"Systematic review and meta-analysis of cannabinoids in palliative medicine","volume":"9","author":"Mucke","year":"2018","journal-title":"J\u00a0Cachexia Sarcopenia Muscle"},{"issue":"2","key":"10.1016\/j.mcna.2020.01.004_bib25","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1002\/2327-6924.12422","article-title":"State of the evidence: Cannabinoids and cancer pain-A systematic review","volume":"29","author":"Tateo","year":"2017","journal-title":"J\u00a0Am Assoc Nurse Pract"},{"issue":"3","key":"10.1016\/j.mcna.2020.01.004_bib26","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1177\/2049463717710042","article-title":"Sativex oromucosal spray as adjunctive therapy in advanced cancer patients with chronic pain unalleviated by optimized opioid therapy: two double-blind, randomized, placebo-controlled phase 3 studies","volume":"11","author":"Fallon","year":"2017","journal-title":"Br J Pain"},{"issue":"5","key":"10.1016\/j.mcna.2020.01.004_bib27","first-page":"438","article-title":"Nabiximols for opioid-treated cancer patients with poorly-controlled chronic pain: a randomized, placebo-controlled, graded-dose trial","volume":"13","author":"Portenoy","year":"2012","journal-title":"J\u00a0Pain"},{"key":"10.1016\/j.mcna.2020.01.004_bib28","first-page":"2864384","article-title":"Medical cannabinoids for cancer cachexia: a systematic review and meta-analysis","volume":"2019","author":"Wang","year":"2019","journal-title":"Biomed Res Int"},{"issue":"2","key":"10.1016\/j.mcna.2020.01.004_bib29","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.jpainsymman.2009.06.008","article-title":"Multicenter, double-blind, randomized, placebo-controlled, parallel-group study of the efficacy, safety, and tolerability of THC:CBD extract and THC extract in patients with intractable cancer-related pain","volume":"39","author":"Johnson","year":"2010","journal-title":"J\u00a0Pain Symptom Manage"},{"issue":"21","key":"10.1016\/j.mcna.2020.01.004_bib30","doi-asserted-by":"crossref","first-page":"3394","DOI":"10.1200\/JCO.2005.05.1847","volume":"24","author":"Strasser","year":"2006","journal-title":"J\u00a0Clin Oncol"},{"issue":"24","key":"10.1016\/j.mcna.2020.01.004_bib31","doi-asserted-by":"crossref","first-page":"2456","DOI":"10.1001\/jama.2015.6358","article-title":"Cannabinoids for medical use: a systematic review and meta-analysis","volume":"313","author":"Whiting","year":"2015","journal-title":"JAMA"},{"issue":"1","key":"10.1016\/j.mcna.2020.01.004_bib32","doi-asserted-by":"crossref","first-page":"1","DOI":"10.15585\/mmwr.rr6501e1","article-title":"CDC guideline for prescribing opioids for chronic pain - United States, 2016","volume":"65","author":"Dowell","year":"2016","journal-title":"MMWR Recomm Rep"},{"issue":"7","key":"10.1016\/j.mcna.2020.01.004_bib34","doi-asserted-by":"crossref","first-page":"1230","DOI":"10.1377\/hlthaff.2015.1661","article-title":"Medical marijuana laws reduce prescription medication use in medicare part D","volume":"35","author":"Bradford","year":"2016","journal-title":"Health Aff (Millwood)"},{"issue":"10","key":"10.1016\/j.mcna.2020.01.004_bib35","doi-asserted-by":"crossref","first-page":"1932","DOI":"10.1097\/j.pain.0000000000001293","article-title":"Cannabis and cannabinoids for the treatment of people with chronic noncancer pain conditions: a systematic review and meta-analysis of controlled and observational studies","volume":"159","author":"Stockings","year":"2018","journal-title":"Pain"},{"issue":"6","key":"10.1016\/j.mcna.2020.01.004_bib36","doi-asserted-by":"crossref","first-page":"e755","DOI":"10.36076\/ppj.20.5.E755","article-title":"Efficacy of Cannabis-based medicines for pain management: a systematic review and meta-analysis of randomized controlled trials","volume":"20","author":"Aviram","year":"2017","journal-title":"Pain Physician"},{"issue":"3","key":"10.1016\/j.mcna.2020.01.004_bib37","article-title":"Cannabis-based medicines for chronic neuropathic pain in adults","author":"Mucke","year":"2018","journal-title":"Cochrane Database Syst Rev"},{"issue":"5","key":"10.1016\/j.mcna.2020.01.004_bib38","doi-asserted-by":"crossref","first-page":"319","DOI":"10.7326\/M17-0155","article-title":"The effects of cannabis among adults with chronic pain and an overview of general harms: a systematic review","volume":"167","author":"Nugent","year":"2017","journal-title":"Ann Intern Med"},{"issue":"9","key":"10.1016\/j.mcna.2020.01.004_bib39","first-page":"982","article-title":"An exploratory human laboratory experiment evaluating vaporized cannabis in the treatment of neuropathic pain from spinal cord injury and disease","volume":"17","author":"Wilsey","year":"2016","journal-title":"J\u00a0Pain"},{"issue":"7","key":"10.1016\/j.mcna.2020.01.004_bib40","doi-asserted-by":"crossref","first-page":"999","DOI":"10.1002\/j.1532-2149.2013.00445.x","article-title":"A\u00a0double-blind, randomized, placebo-controlled, parallel group study of THC\/CBD spray in peripheral neuropathic pain treatment","volume":"18","author":"Serpell","year":"2014","journal-title":"Eur J Pain"},{"key":"10.1016\/j.mcna.2020.01.004_bib41","doi-asserted-by":"crossref","DOI":"10.1177\/2042098619846993","article-title":"Safety and effectiveness of cannabinoids for the treatment of neuropsychiatric symptoms in dementia: a systematic review","volume":"10","author":"Hillen","year":"2019","journal-title":"Ther Adv Drug Saf"},{"issue":"13","key":"10.1016\/j.mcna.2020.01.004_bib42","doi-asserted-by":"crossref","first-page":"1669","DOI":"10.1503\/cmaj.071178","article-title":"Adverse effects of medical cannabinoids: a systematic review","volume":"178","author":"Wang","year":"2008","journal-title":"CMAJ"}],"container-title":["Medical Clinics of North America"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0025712520300043?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0025712520300043?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,21]],"date-time":"2025-09-21T01:45:04Z","timestamp":1758419104000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0025712520300043"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,5]]},"references-count":39,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2020,5]]}},"alternative-id":["S0025712520300043"],"URL":"https:\/\/doi.org\/10.1016\/j.mcna.2020.01.004","relation":{},"ISSN":["0025-7125"],"issn-type":[{"value":"0025-7125","type":"print"}],"subject":[],"published":{"date-parts":[[2020,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cannabis for Symptom Management in Older Adults","name":"articletitle","label":"Article Title"},{"value":"Medical Clinics of North America","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.mcna.2020.01.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}