{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T06:14:04Z","timestamp":1791008044761,"version":"4.1.0"},"reference-count":18,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2004,4,1]],"date-time":"2004-04-01T00:00:00Z","timestamp":1080777600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecular and Cellular Probes"],"published-print":{"date-parts":[[2004,4]]},"DOI":"10.1016\/j.mcp.2003.10.003","type":"journal-article","created":{"date-parts":[[2003,12,23]],"date-time":"2003-12-23T10:47:38Z","timestamp":1072176458000},"page":"117-122","source":"Crossref","is-referenced-by-count":51,"title":["Short PNA molecular beacons for real-time PCR allelic discrimination of single nucleotide polymorphisms"],"prefix":"10.1016","volume":"18","author":[{"given":"Kenneth","family":"Petersen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ulla","family":"Vogel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eszter","family":"Rockenbauer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kirsten","family":"Vang Nielsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steen","family":"K\u00f8lvraa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lars","family":"Bolund","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bj\u00f8rn","family":"Nex\u00f8","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.mcp.2003.10.003_BIB1","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1101\/gr.8.8.769","article-title":"Reading bits of genetic information: methods for single-nucleotide polymorphism analysis","volume":"8","author":"Landegren","year":"1998","journal-title":"Genome Res"},{"key":"10.1016\/j.mcp.2003.10.003_BIB2","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1586\/14737159.3.1.17","article-title":"Single-nucleotide polymorphism detection using peptide nucleic acids","volume":"3","author":"Igloi","year":"2003","journal-title":"Expert Rev Mol Diagn"},{"key":"10.1016\/j.mcp.2003.10.003_BIB3","doi-asserted-by":"crossref","first-page":"130","DOI":"10.2144\/97221bi01","article-title":"Continuos fluorescence monitoring of rapid cycle DNA amplification","volume":"22","author":"Wittwer","year":"1997","journal-title":"Biotechniques"},{"key":"10.1016\/j.mcp.2003.10.003_BIB4","doi-asserted-by":"crossref","first-page":"1141","DOI":"10.1093\/clinchem\/45.8.1141","article-title":"Rapid, homogeneous genotyping of the 4G\/5G polymorphism in the promoter region of the PAII gene by fluorescence resonance energy transfer and probe melting curvesr","volume":"45","author":"Nauck","year":"1999","journal-title":"Clin Chem"},{"key":"10.1016\/j.mcp.2003.10.003_BIB5","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1006\/abio.2000.4534","article-title":"Light-up probes: thiazole orange-conjugated peptide nucleic acid for detection of target nucleic acid in homogeneous solution","volume":"281","author":"Svanvik","year":"2000","journal-title":"Anal Biochem"},{"key":"10.1016\/j.mcp.2003.10.003_BIB6","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1038\/nbt0396-303","article-title":"Molecular beacons: probes that fluoresce upon hybridization","volume":"14","author":"Tyagi","year":"1996","journal-title":"Nat Biotechnol"},{"key":"10.1016\/j.mcp.2003.10.003_BIB7","doi-asserted-by":"crossref","first-page":"804","DOI":"10.1038\/11751","article-title":"Detection of PCR products using self-probing amplicons and fluorescence","volume":"17","author":"Whitcombe","year":"1999","journal-title":"Nat Biotechnol"},{"key":"10.1016\/j.mcp.2003.10.003_BIB8","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1101\/gr.170401","article-title":"Self-reporting PNA\/DNA primers for PCR analysis","volume":"11","author":"Fiandaca","year":"2001","journal-title":"Genome Res"},{"key":"10.1016\/j.mcp.2003.10.003_BIB9","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1101\/gr.4.6.357","article-title":"Oligonucleotides with fluorescent dyes at opposite ends provide a quenched probe system useful for detecting PCR product and nucleic acid hybridization","volume":"4","author":"Livak","year":"1995","journal-title":"PCR Meth Appl"},{"key":"10.1016\/j.mcp.2003.10.003_BIB10","doi-asserted-by":"crossref","first-page":"7276","DOI":"10.1073\/pnas.88.16.7276","article-title":"Detection of specific polymerase chain reaction product by utilizing the 5\u2032\u20133\u2032 exonuclease activity of Thermus aquaticus DNA polymerase","volume":"88","author":"Holland","year":"1991","journal-title":"Proc Natl Acad Sci"},{"key":"10.1016\/j.mcp.2003.10.003_BIB11","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1021\/ja0041324","article-title":"Hybridization of DNA and PNA molecular beacons to single-stranded and double-stranded DNA targets","volume":"124","author":"Kuhn","year":"2002","journal-title":"J Am Chem Soc"},{"key":"10.1016\/j.mcp.2003.10.003_BIB12_1","doi-asserted-by":"crossref","first-page":"3249","DOI":"10.1002\/1521-3773(20000915)39:18<3249::AID-ANIE3249>3.0.CO;2-M","article-title":"Solid-phase synthesis of doubly labeled peptide nucleic acids as probes for the real-time detection of hybridization","volume":"39","author":"Seitz","year":"2000","journal-title":"Angew Chem\u2014Int Ed"},{"key":"10.1016\/j.mcp.2003.10.003_BIB12_2","unstructured":"Coull JM, Gildea BD, Hyldig-Nielsen JJ. WO-A9922018; 1999."},{"key":"10.1016\/j.mcp.2003.10.003_BIB12_3","unstructured":"Gildea BD, Coull JM, Hyldig-Nielsen JJ, Fiandaca MJ. WO-A9921881; 1999."},{"key":"10.1016\/j.mcp.2003.10.003_BIB13","doi-asserted-by":"crossref","first-page":"7255","DOI":"10.1016\/S0040-4039(98)01581-0","article-title":"PNA solubility enhancers","volume":"39","author":"Gildea","year":"1998","journal-title":"Tetrahedron Lett"},{"key":"10.1016\/j.mcp.2003.10.003_BIB14","first-page":"77","article-title":"Polymorphisms in the DNA repair gene XPD: correlations with risk and age at onset of basal cell carcinoma","volume":"8","author":"Dybdahl","year":"1999","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"10.1016\/j.mcp.2003.10.003_BIB15","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1111\/j.1399-3011.1997.tb01124.x","article-title":"Improvements in automated PNA synthesis using Boc\/Z monomers","volume":"49","author":"Koch","year":"1997","journal-title":"J Pept Res"},{"key":"10.1016\/j.mcp.2003.10.003_BIB16","doi-asserted-by":"crossref","first-page":"5332","DOI":"10.1093\/nar\/21.23.5332","article-title":"Single base pair mutation analysis by PNA directed PCR clamping","volume":"21","author":"\u00d8rum","year":"1993","journal-title":"Nucleic Acids Res"}],"container-title":["Molecular and Cellular Probes"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0890850803001105?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0890850803001105?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,3,28]],"date-time":"2020-03-28T10:10:33Z","timestamp":1585390233000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0890850803001105"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,4]]},"references-count":18,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2004,4]]}},"alternative-id":["S0890850803001105"],"URL":"https:\/\/doi.org\/10.1016\/j.mcp.2003.10.003","relation":{},"ISSN":["0890-8508"],"issn-type":[{"value":"0890-8508","type":"print"}],"subject":[],"published":{"date-parts":[[2004,4]]}}}