{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T14:55:03Z","timestamp":1770994503400,"version":"3.50.1"},"reference-count":24,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Molecular and Cellular Probes"],"published-print":{"date-parts":[[2020,12]]},"DOI":"10.1016\/j.mcp.2020.101653","type":"journal-article","created":{"date-parts":[[2020,8,28]],"date-time":"2020-08-28T11:27:08Z","timestamp":1598614028000},"page":"101653","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":15,"special_numbering":"C","title":["miR-708 affords protective efficacy in anoxia\/reoxygenation-stimulated cardiomyocytes by blocking the TLR4 signaling via targeting HMGB1"],"prefix":"10.1016","volume":"54","author":[{"given":"Shuping","family":"Zhang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ping","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jin","family":"Xuan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.mcp.2020.101653_bib1","doi-asserted-by":"crossref","first-page":"e56","DOI":"10.1161\/CIR.0000000000000659","article-title":"Heart disease and stroke statistics-2019 update: a report from the American heart association","volume":"139","author":"Benjamin","year":"2019","journal-title":"Circulation"},{"key":"10.1016\/j.mcp.2020.101653_bib2","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1093\/ehjqcco\/qcw041","article-title":"Increasing mortality from ischaemic heart disease in China from 2004 to 2010: disproportionate rise in rural areas and elderly subjects. 438 million person-years follow-up","volume":"3","author":"Zhang","year":"2017","journal-title":"Eur Heart J Qual Care Clin Outcomes"},{"key":"10.1016\/j.mcp.2020.101653_bib3","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0117446","article-title":"Recent trends in economic burden of acute myocardial infarction in South Korea","volume":"10","author":"Seo","year":"2015","journal-title":"PloS One"},{"key":"10.1016\/j.mcp.2020.101653_bib4","doi-asserted-by":"crossref","DOI":"10.1155\/2013\/864962","article-title":"The Economic Burden of HIV\/AIDS and myocardial infarction treatment in Brazil","volume":"2013","author":"Araujo","year":"2013","journal-title":"Scientific World J"},{"key":"10.1016\/j.mcp.2020.101653_bib5","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/j.ijcard.2017.11.038","article-title":"Ethyl pyruvate attenuates myocardial ischemia-reperfusion injury exacerbated by hyperglycemia via retained inhibitory effect on HMGB1","volume":"252","author":"Soh","year":"2018","journal-title":"Int. J. Cardiol."},{"key":"10.1016\/j.mcp.2020.101653_bib6","doi-asserted-by":"crossref","DOI":"10.1155\/2016\/1656450","article-title":"The role of oxidative stress in myocardial ischemia and reperfusion injury and remodeling: revisited","volume":"2016","author":"Kurian","year":"2016","journal-title":"Oxid Med Cell Longev"},{"key":"10.1016\/j.mcp.2020.101653_bib7","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.intimp.2019.01.002","article-title":"Glycyrrhizin attenuates hepatic ischemia-reperfusion injury by suppressing HMGB1-dependent GSDMD-mediated kupffer cells pyroptosis","volume":"68","author":"Hua","year":"2019","journal-title":"Int. Immunopharm."},{"key":"10.1016\/j.mcp.2020.101653_bib8","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1007\/s00392-011-0409-x","article-title":"HMGB1 is an independent predictor of death and heart transplantation in heart failure","volume":"101","author":"Volz","year":"2012","journal-title":"Clin. Res. Cardiol."},{"key":"10.1016\/j.mcp.2020.101653_bib9","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1080\/01616412.2018.1497254","article-title":"Association of circulating blood HMGB1 levels with ischemic stroke: a systematic review and meta-analysis","volume":"40","author":"Le","year":"2018","journal-title":"Neurol. Res."},{"key":"10.1016\/j.mcp.2020.101653_bib10","first-page":"1273","article-title":"Quercetin attenuates myocardial ischemia-reperfusion injury via downregulation of the HMGB1-TLR4-NF-kappaB signaling pathway","volume":"10","author":"Dong","year":"2018","journal-title":"Am J Transl Res"},{"key":"10.1016\/j.mcp.2020.101653_bib11","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1152\/physiolgenomics.00130.2010","article-title":"The role of microRNA in modulating myocardial ischemia-reperfusion injury","volume":"43","author":"Ye","year":"2011","journal-title":"Physiol. Genom."},{"key":"10.1016\/j.mcp.2020.101653_bib12","doi-asserted-by":"crossref","first-page":"782","DOI":"10.1002\/ejhf.323","article-title":"Up-regulation of micro-RNA765 in human failing hearts is associated with post-transcriptional regulation of protein phosphatase inhibitor-1 and depressed contractility","volume":"17","author":"Cai","year":"2015","journal-title":"Eur. J. Heart Fail."},{"key":"10.1016\/j.mcp.2020.101653_bib13","doi-asserted-by":"crossref","first-page":"3439","DOI":"10.2147\/DDDT.S177128","article-title":"miR-708-5p promotes fibroblast-like synoviocytes' cell apoptosis and ameliorates rheumatoid arthritis by the inhibition of Wnt3a\/beta-catenin pathway","volume":"12","author":"Wu","year":"2018","journal-title":"Drug Des. Dev. Ther."},{"key":"10.1016\/j.mcp.2020.101653_bib14","doi-asserted-by":"crossref","first-page":"22599","DOI":"10.1038\/srep22599","article-title":"MiR-708 promotes steroid-induced osteonecrosis of femoral head, suppresses osteogenic differentiation by targeting SMAD3","volume":"6","author":"Hao","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.mcp.2020.101653_bib15","doi-asserted-by":"crossref","DOI":"10.3390\/ijms17060875","article-title":"Neonatal heart-enriched miR-708 promotes differentiation of cardiac progenitor cells in rats","volume":"17","author":"Deng","year":"2016","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.mcp.2020.101653_bib16","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1016\/j.yexmp.2008.09.002","article-title":"Effects of HMGB1 on PMN apoptosis during LPS-induced acute lung injury","volume":"85","author":"Feng","year":"2008","journal-title":"Exp. Mol. Pathol."},{"key":"10.1016\/j.mcp.2020.101653_bib17","first-page":"8344","article-title":"High-mobility group Box-1 regulates acute myocardial ischemia-induced injury through the toll-like receptor 4-related pathway","volume":"10","author":"Bai","year":"2017","journal-title":"Int. J. Clin. Exp. Pathol."},{"key":"10.1016\/j.mcp.2020.101653_bib18","first-page":"4565630","article-title":"Remote ischemic postconditioning protects against myocardial ischemia-reperfusion injury by inhibition of the RAGE-HMGB1 pathway","volume":"2018","author":"Wang","year":"2018","journal-title":"BioMed Res. Int."},{"key":"10.1016\/j.mcp.2020.101653_bib19","unstructured":"Jingguo Wu, Nan Xun, Yang Yang, Lijin Zeng, Zhenyu Li, Wen Yang, Yanbing Liang, Hao Tang, Zhongfu Ma, Chrysin attenuates myocardial ischemia\u2013reperfusion injury by inhibiting myocardial inflammation, RSC Adv. 8."},{"key":"10.1016\/j.mcp.2020.101653_bib20","doi-asserted-by":"crossref","DOI":"10.3390\/antiox9020167","article-title":"Cocoa flavonoids reduce inflammation and oxidative stress in a myocardial ischemia-reperfusion experimental model","volume":"9","author":"Ahmed","year":"2020","journal-title":"Antioxidants"},{"key":"10.1016\/j.mcp.2020.101653_bib21","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1161\/CIRCRESAHA.116.310266","article-title":"ATF6 decreases myocardial ischemia\/reperfusion damage and links ER stress and oxidative stress signaling pathways in the heart","volume":"120","author":"Jin","year":"2017","journal-title":"Circ. Res."},{"key":"10.1016\/j.mcp.2020.101653_bib22","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.neulet.2017.11.017","article-title":"Inhibition of JAK1 by microRNA-708 promotes SH-SY5Y neuronal cell survival after oxygen and glucose deprivation and reoxygenation","volume":"664","author":"Huang","year":"2018","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.mcp.2020.101653_bib23","doi-asserted-by":"crossref","first-page":"1391","DOI":"10.1038\/nm.2507","article-title":"Ischemia and reperfusion-from mechanism to translation","volume":"17","author":"Eltzschig","year":"2011","journal-title":"Nat. Med."},{"key":"10.1016\/j.mcp.2020.101653_bib24","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.pharmthera.2018.01.001","article-title":"Inflammation following acute myocardial infarction: multiple players, dynamic roles, and novel therapeutic opportunities","volume":"186","author":"Ong","year":"2018","journal-title":"Pharmacol. Ther."}],"container-title":["Molecular and Cellular Probes"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0890850820303455?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0890850820303455?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T14:15:47Z","timestamp":1760192147000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0890850820303455"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,12]]},"references-count":24,"alternative-id":["S0890850820303455"],"URL":"https:\/\/doi.org\/10.1016\/j.mcp.2020.101653","relation":{},"ISSN":["0890-8508"],"issn-type":[{"value":"0890-8508","type":"print"}],"subject":[],"published":{"date-parts":[[2020,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"miR-708 affords protective efficacy in anoxia\/reoxygenation-stimulated cardiomyocytes by blocking the TLR4 signaling via targeting HMGB1","name":"articletitle","label":"Article Title"},{"value":"Molecular and Cellular Probes","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.mcp.2020.101653","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"101653"}}