{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T20:29:57Z","timestamp":1791232197261,"version":"4.1.0"},"reference-count":31,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,8,2]],"date-time":"2024-08-02T00:00:00Z","timestamp":1722556800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002597","name":"Kyung Hee University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002597","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003710","name":"Korea Health Industry Development Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003710","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003625","name":"Ministry of Health and Welfare","doi-asserted-by":"publisher","award":["HI17C0778"],"award-info":[{"award-number":["HI17C0778"]}],"id":[{"id":"10.13039\/501100003625","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003625","name":"Ministry of Health and Welfare","doi-asserted-by":"publisher","award":["HR22C1605"],"award-info":[{"award-number":["HR22C1605"]}],"id":[{"id":"10.13039\/501100003625","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["mcponline.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Molecular & Cellular Proteomics"],"published-print":{"date-parts":[[2024,9]]},"DOI":"10.1016\/j.mcpro.2024.100826","type":"journal-article","created":{"date-parts":[[2024,8,5]],"date-time":"2024-08-05T18:14:35Z","timestamp":1722881675000},"page":"100826","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":11,"title":["Systematic Proteome Profiling of Maternal Plasma for Development of Preeclampsia Biomarkers"],"prefix":"10.1016","volume":"23","author":[{"given":"Ji Hyae","family":"Lim","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jae Min","family":"Lim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyeong Min","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyun Jung","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong Wook","family":"Kwak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"You Jung","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Moon Young","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sang Hee","family":"Jung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Young Ran","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyun Mee","family":"Ryu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0095-3787","authenticated-orcid":false,"given":"Kwang Pyo","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.mcpro.2024.100826_bib1","doi-asserted-by":"crossref","first-page":"e237","DOI":"10.1097\/AOG.0000000000003891","article-title":"Gestational hypertension and preeclampsia: ACOG Practice Bulletin, Number 222","volume":"135","year":"2020","journal-title":"Obstet. Gynecol."},{"key":"10.1016\/j.mcpro.2024.100826_bib2","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1002\/uog.23640","article-title":"Stratification of pregnancy care based on risk of pre-eclampsia derived from biophysical and biochemical markers at 19-24 weeks' gestation","volume":"58","author":"Litwinska","year":"2021","journal-title":"Ultrasound Obstet. Gynecol."},{"key":"10.1016\/j.mcpro.2024.100826_bib3","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1161\/HYPERTENSIONAHA.121.18021","article-title":"Prospective evaluation of international prediction of pregnancy complications collaborative network models for prediction of preeclampsia: role of Serum sFlt-1 at 11-13 Weeks' Gestation","volume":"79","author":"Chaiyasit","year":"2021","journal-title":"Hypertension"},{"key":"10.1016\/j.mcpro.2024.100826_bib4","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1002\/ijgo.13763","volume":"154","author":"Poon","year":"2021","journal-title":"Int. J. Gynaecol. Obstet."},{"key":"10.1016\/j.mcpro.2024.100826_bib5","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/j.placenta.2021.07.297","article-title":"Placenta morphology and biomarkers in pregnancies with congenital heart disease - a systematic review","volume":"112","author":"Snoep","year":"2021","journal-title":"Placenta"},{"key":"10.1016\/j.mcpro.2024.100826_bib6","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1161\/HYPERTENSIONAHA.119.13348","article-title":"Soluble endoglin as a marker for preeclampsia, its severity, and the occurrence of adverse outcomes","volume":"74","author":"Lea\u00f1os-Miranda","year":"2019","journal-title":"Hypertension"},{"key":"10.1016\/j.mcpro.2024.100826_bib7","doi-asserted-by":"crossref","first-page":"1403","DOI":"10.1097\/AOG.0b013e3181719b7a","article-title":"Effective prediction of preeclampsia by a combined ratio of angiogenesis-related factors","volume":"111","author":"Lim","year":"2008","journal-title":"Obstet. Gynecol."},{"key":"10.1016\/j.mcpro.2024.100826_bib8","doi-asserted-by":"crossref","DOI":"10.1093\/database\/baab065","article-title":"HBFP: a new repository for human body fluid proteome","volume":"2021","author":"Shao","year":"2021","journal-title":"Database (Oxford)"},{"key":"10.1016\/j.mcpro.2024.100826_bib9","doi-asserted-by":"crossref","first-page":"3890","DOI":"10.3390\/cancers13153890","article-title":"Mass spectrometry-based proteomic discovery of prognostic biomarkers in adrenal cortical carcinoma","volume":"13","author":"Jang","year":"2021","journal-title":"Cancers (Basel)"},{"key":"10.1016\/j.mcpro.2024.100826_bib10","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1038\/s41585-021-00500-1","article-title":"Proteomic discovery of non-invasive biomarkers of localized prostate cancer using mass spectrometry","volume":"18","author":"Khoo","year":"2021","journal-title":"Nat. Rev. Urol."},{"key":"10.1016\/j.mcpro.2024.100826_bib11","doi-asserted-by":"crossref","first-page":"8021","DOI":"10.3390\/ijms22158021","article-title":"Clinical proteomics of biofluids in haematological malignancies","volume":"22","author":"Dunphy","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.mcpro.2024.100826_bib12","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0065571","article-title":"Peptidomic identification of serum peptides diagnosing preeclampsia","volume":"8","author":"Wen","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.mcpro.2024.100826_bib13","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1186\/s13148-020-00918-1","article-title":"Epigenome-wide DNA methylation profiling of preeclamptic placenta according to severe features","volume":"12","author":"Lim","year":"2020","journal-title":"Clin. Epigenet."},{"key":"10.1016\/j.mcpro.2024.100826_bib14","doi-asserted-by":"crossref","first-page":"1342","DOI":"10.1158\/0008-5472.CAN-19-2288","article-title":"Breast cancer cell-derived soluble CD44 promotes tumor progression by triggering macrophage IL1\u03b2 production","volume":"80","author":"Jang","year":"2020","journal-title":"Cancer Res."},{"key":"10.1016\/j.mcpro.2024.100826_bib15","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1016\/j.jmoldx.2015.12.002","article-title":"Novel epigenetic markers on chromosome 21 for noninvasive prenatal testing of fetal trisomy 21","volume":"18","author":"Lee","year":"2016","journal-title":"J.\u00a0Mol. Diagn."},{"key":"10.1016\/j.mcpro.2024.100826_bib16","doi-asserted-by":"crossref","first-page":"427","DOI":"10.3858\/emm.2011.43.7.047","article-title":"Discovery of the serum biomarker proteins in severe preeclampsia by proteomic analysis","volume":"43","author":"Park","year":"2011","journal-title":"Exp. Mol. Med."},{"key":"10.1016\/j.mcpro.2024.100826_bib17","doi-asserted-by":"crossref","first-page":"1581","DOI":"10.1002\/pmic.201500381","article-title":"Expression changes of proteins associated with the development of preeclampsia in maternal plasma: a case-control study","volume":"16","author":"Kim","year":"2016","journal-title":"Proteomics"},{"key":"10.1016\/j.mcpro.2024.100826_bib18","doi-asserted-by":"crossref","first-page":"2383","DOI":"10.1056\/NEJMoa1409065","article-title":"HDL cholesterol efflux capacity and incident cardiovascular events","volume":"371","author":"Rohatgi","year":"2014","journal-title":"N.\u00a0Engl. J. Med."},{"key":"10.1016\/j.mcpro.2024.100826_bib19","doi-asserted-by":"crossref","first-page":"1186","DOI":"10.1194\/jlr.M071985","article-title":"Increased maternal and fetal cholesterol efflux capacity and placental CYP27A1 expression in preeclampsia","volume":"58","author":"Mistry","year":"2017","journal-title":"J.\u00a0Lipid Res."},{"key":"10.1016\/j.mcpro.2024.100826_bib20","doi-asserted-by":"crossref","first-page":"1895","DOI":"10.3109\/14767058.2014.972926","article-title":"Relationship of neutrophil gelatinase-associated lipocalin (NGAL) and procalcitonin levels with the presence and severity of the preeclampsia","volume":"28","author":"Artunc-Ulkumen","year":"2015","journal-title":"J.\u00a0Matern. Fetal Neonatal. Med."},{"key":"10.1016\/j.mcpro.2024.100826_bib21","doi-asserted-by":"crossref","first-page":"291","DOI":"10.3109\/14767058.2010.487138","article-title":"Plasma lipocalin-2 levels in pregnant women with pre-eclampsia, and their relation with severity of disease","volume":"24","author":"Cemgil Arikan","year":"2011","journal-title":"J.\u00a0Matern. Fetal Neonatal. Med."},{"key":"10.1016\/j.mcpro.2024.100826_bib22","doi-asserted-by":"crossref","first-page":"518","DOI":"10.12816\/0037801","article-title":"A\u00a0study of effect of experimental pre-eclampsia on plasma lipocalin-2 level in rats","volume":"67","author":"Mohamed","year":"2017","journal-title":"Egypt. J Hosp. Med."},{"key":"10.1016\/j.mcpro.2024.100826_bib23","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1177\/1933719113477480","article-title":"Circulating levels of neutrophil gelatinase-associated lipocalin (NGAL) correlate with the presence and severity of preeclampsia","volume":"20","author":"Kim","year":"2013","journal-title":"Reprod. Sci."},{"key":"10.1016\/j.mcpro.2024.100826_bib24","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.ejogrb.2016.08.034","article-title":"Prediction of pre-eclampsia combining NGAL and other biochemical markers with Doppler in the first and\/or second trimester of pregnancy. A pilot study","volume":"205","author":"Karampas","year":"2016","journal-title":"Eur. J. Obstet. Gynecol. Reprod. Biol."},{"key":"10.1016\/j.mcpro.2024.100826_bib25","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1089\/ars.2013.5572","article-title":"The emerging role of QSOX1 in cancer","volume":"21","author":"Lake","year":"2014","journal-title":"Antioxid. Redox Signal."},{"key":"10.1016\/j.mcpro.2024.100826_bib26","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1262\/jrd.2012-053","article-title":"Oxidative stress produced by xanthine oxidase induces apoptosis in human extravillous trophoblast cells","volume":"59","author":"Murata","year":"2013","journal-title":"J.\u00a0Reprod. Dev."},{"key":"10.1016\/j.mcpro.2024.100826_bib27","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1016\/j.arcmed.2014.10.003","article-title":"Early disturbed placental ischemia and hypoxia creates immune alteration and vascular disorder causing preeclampsia","volume":"45","author":"Z\u00e1rate","year":"2014","journal-title":"Arch. Med. Res."},{"key":"10.1016\/j.mcpro.2024.100826_bib28","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/j.mam.2016.12.003","article-title":"Adenosine and preeclampsia","volume":"55","author":"Salsoso","year":"2017","journal-title":"Mol. Aspects Med."},{"key":"10.1016\/j.mcpro.2024.100826_bib29","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1080\/10641955.2016.1259627","article-title":"Relationship between hypoxia and downstream pathogenic pathways in preeclampsia","volume":"36","author":"Korkes","year":"2017","journal-title":"Hypertens. Pregnancy"},{"key":"10.1016\/j.mcpro.2024.100826_bib30","doi-asserted-by":"crossref","first-page":"105","DOI":"10.2174\/1573402115666190119163942","article-title":"The role of oxidative stress, adhesion molecules and antioxidants in preeclampsia","volume":"15","author":"Haram","year":"2019","journal-title":"Curr. Hypertens. Rev."},{"key":"10.1016\/j.mcpro.2024.100826_bib31","doi-asserted-by":"crossref","first-page":"3708","DOI":"10.1080\/14767058.2018.1471459","article-title":"QSOX1 regulates trophoblastic apoptosis in preeclampsia through hydrogen peroxide production","volume":"32","author":"Li","year":"2019","journal-title":"J.\u00a0Matern. Fetal Neonatal. Med."}],"container-title":["Molecular & Cellular Proteomics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1535947624001166?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1535947624001166?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T22:51:44Z","timestamp":1727823104000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1535947624001166"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9]]},"references-count":31,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2024,9]]}},"alternative-id":["S1535947624001166"],"URL":"https:\/\/doi.org\/10.1016\/j.mcpro.2024.100826","relation":{},"ISSN":["1535-9476"],"issn-type":[{"value":"1535-9476","type":"print"}],"subject":[],"published":{"date-parts":[[2024,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Systematic Proteome Profiling of Maternal Plasma for Development of Preeclampsia Biomarkers","name":"articletitle","label":"Article Title"},{"value":"Molecular & Cellular Proteomics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.mcpro.2024.100826","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Authors. Published by Elsevier Inc on behalf of American Society for Biochemistry and Molecular Biology.","name":"copyright","label":"Copyright"}],"article-number":"100826"}}