{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,5,26]],"date-time":"2023-05-26T23:10:18Z","timestamp":1685142618966},"reference-count":66,"publisher":"Elsevier BV","issue":"13","license":[{"start":{"date-parts":[[2009,10,1]],"date-time":"2009-10-01T00:00:00Z","timestamp":1254355200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicina Cl\u00ednica"],"published-print":{"date-parts":[[2009,10]]},"DOI":"10.1016\/j.medcli.2009.09.002","type":"journal-article","created":{"date-parts":[[2009,9,26]],"date-time":"2009-09-26T08:37:56Z","timestamp":1253954276000},"page":"513-521","source":"Crossref","is-referenced-by-count":11,"title":["Principales caracter\u00edsticas de la pandemia por el nuevo virus influenza A (H1N1)"],"prefix":"10.1016","volume":"133","author":[{"given":"Josep","family":"Vaqu\u00e9 Rafart","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julita","family":"Gil Cuesta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda","family":"Brotons Agull\u00f3","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.medcli.2009.09.002_bib1","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1157\/13084540","article-title":"La amenaza de una pandemia humana por gripe aviar","volume":"126","author":"Vaqu\u00e9","year":"2006","journal-title":"Med Clin (Barc)"},{"key":"10.1016\/j.medcli.2009.09.002_bib2","unstructured":"WHO. World now at the start of 2009 influenza pandemic. Statement to the press by WHO Director-General Dr Margaret Chan. 11 June 2009 [consultado 18\/6\/2009]. Disponible en: http:\/\/www.who.int\/mediacentre\/news\/statements\/2009\/h1n1_pandemic_phase6_20090611\/en\/index.html"},{"key":"10.1016\/j.medcli.2009.09.002_bib3","doi-asserted-by":"crossref","first-page":"15","DOI":"10.3201\/eid1209.05-0979","article-title":"1918 influenza: the mother of all pandemics","volume":"12","author":"Taubenberger","year":"2006","journal-title":"Emerg Infect Dis"},{"key":"10.1016\/j.medcli.2009.09.002_bib4","doi-asserted-by":"crossref","first-page":"2209","DOI":"10.1056\/NEJMp058281","article-title":"The origins of pandemic influenza-lessons from the 1918 virus","volume":"353","author":"Belshe","year":"2005","journal-title":"N Engl J Med"},{"key":"10.1016\/j.medcli.2009.09.002_bib5","series-title":"Control of communicable diseases manual","author":"Heyman","year":"2008"},{"key":"10.1016\/j.medcli.2009.09.002_bib6","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1086\/515616","article-title":"Pandemic versus epidemic influenza mortality: a pattern on changing age distribution","volume":"178","author":"Simonsen","year":"1998","journal-title":"J Infect Dis"},{"key":"10.1016\/j.medcli.2009.09.002_bib7","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1093\/oxfordjournals.epirev.a017917","article-title":"Emerging infections: Pandemic influenza","volume":"18","author":"Glezen","year":"1996","journal-title":"Epidemiol Rev"},{"key":"10.1016\/j.medcli.2009.09.002_bib8","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1126\/science.1176225","article-title":"Antigenic and genetic characteristics of swine-origin 2009 A (H1N1) influenza viruses circulating in humans","volume":"325","author":"Garten","year":"2009","journal-title":"Science"},{"key":"10.1016\/j.medcli.2009.09.002_bib9","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1016\/j.cell.2009.01.029","article-title":"The influenza virus enigma","volume":"136","author":"Salomon","year":"2009","journal-title":"Cell"},{"key":"10.1016\/j.medcli.2009.09.002_bib10","first-page":"400","article-title":"Swine influenza A (H1N1) infection in two children\u2013Southern California, March\u2013April 2009","volume":"58","year":"2009","journal-title":"MMWR"},{"key":"10.1016\/j.medcli.2009.09.002_bib11","doi-asserted-by":"crossref","first-page":"2605","DOI":"10.1056\/NEJMoa0903810","article-title":"Emergence of a novel swine-origin influenza A (N1N1) virus in humans","volume":"360","year":"2009","journal-title":"N Engl J Med"},{"key":"10.1016\/j.medcli.2009.09.002_bib12","first-page":"435","article-title":"Update: Swine influenza A (H1N1) infections\u2013California and Texas, April 2009","volume":"58","year":"2009","journal-title":"MMWR"},{"key":"10.1016\/j.medcli.2009.09.002_bib13","unstructured":"WHO. Influenza-like illness in the United States and Mexico. 24 April 2009 [consultado 19\/6\/2009]. Disponible en: http:\/\/www.who.int\/csr\/don\/2009_04_24\/en\/index.html"},{"key":"10.1016\/j.medcli.2009.09.002_bib14","first-page":"467","article-title":"Outbreak of swine-origin influenza A (H1N1) virus infection\u2013Mexico, March\u2013April 2009","volume":"58","year":"2009","journal-title":"MMWR"},{"key":"10.1016\/j.medcli.2009.09.002_bib15","first-page":"585","article-title":"Update: Novel influenza A (H1N1) virus infection\u2013Mexico, March\u2013May 2009","volume":"58","year":"2009","journal-title":"MMWR"},{"key":"10.1016\/j.medcli.2009.09.002_bib16","first-page":"431","article-title":"Update: Infections with a swine-origin influenza A (H1N1) virus\u2013United States and other countries, April 28, 2009","volume":"58","year":"2009","journal-title":"MMWR"},{"key":"10.1016\/j.medcli.2009.09.002_bib17","first-page":"453","article-title":"Update: Novel Influenza A (H1N1) virus infections\u2013Worldwide, May 6, 2009","volume":"58","year":"2009","journal-title":"MMWR"},{"key":"10.1016\/j.medcli.2009.09.002_bib18","first-page":"173","article-title":"New influenza A (H1N1) virus infections: global surveillance summary, May 2009","volume":"84","year":"2009","journal-title":"WER"},{"key":"10.1016\/j.medcli.2009.09.002_bib19","unstructured":"WHO. Swine influenza. Statement by WHO Director-General Dr Margaret Chan. 27 April 2009 [consultado 18\/6\/2009]. Disponible en: http:\/\/www.who.int\/mediacentre\/news\/statements\/2009\/h1n1_20090427\/en\/index.html."},{"key":"10.1016\/j.medcli.2009.09.002_bib20","unstructured":"WHO. Epidemic and Pandemic Alert and Response. Situation updates. 28 April 2009. Swine influenza-update 4 [consultado 18\/6\/2009]. Disponible en: http:\/\/www.who.int\/csr\/disease\/swineflu\/updates\/en\/index.html."},{"key":"10.1016\/j.medcli.2009.09.002_bib21","unstructured":"WHO. Influenza H1N1. Statement by WHO Director-General Dr Margaret Chan. 29 April 2009 [consultado 18\/6\/2009]. Disponible en: http:\/\/www.who.int\/mediacentre\/news\/statements\/2009\/h1n1_20090427\/en\/index.html."},{"key":"10.1016\/j.medcli.2009.09.002_bib22","first-page":"213","article-title":"Human infection with new influenza A (H1N1) virus: Mexico, update, March\u2013May 2009","volume":"84","year":"2009","journal-title":"WER"},{"key":"10.1016\/j.medcli.2009.09.002_bib23","unstructured":"WHO. Epidemic and Pandemic Alert and Response. Situation updates. 6 May 2009. Swine influenza-update 18 [consultado 22\/6\/2009]. Disponible en: http:\/\/www.who.int\/csr\/disease\/swineflu\/updates\/en\/index.html."},{"key":"10.1016\/j.medcli.2009.09.002_bib24","unstructured":"WHO. Epidemic and Pandemic Alert and Response. Situation updates. 1 June 2009. Swine influenza-update 42 [consultado 22\/6\/2009]. Disponible en: http:\/\/www.who.int\/csr\/disease\/swineflu\/updates\/en\/index.html."},{"key":"10.1016\/j.medcli.2009.09.002_bib25","unstructured":"WHO. Epidemic and Pandemic Alert and Response. Situation updates. 1 July 2009. Swine influenza-update 56 [consultado 6\/7\/2009]. Disponible en: http:\/\/www.who.int\/csr\/disease\/swineflu\/updates\/en\/index.html."},{"key":"10.1016\/j.medcli.2009.09.002_bib26","unstructured":"M\u00e9xico. Situaci\u00f3n actual de la epidemia, 11 de julio de 2009. Estados Unidos Mexicanos, 2009 [consultado 14\/7\/2009]. Disponible en: http:\/\/portal.salud.gob.mx\/contenidos\/sala_prensa\/sala_prensa_prensa\/sala_prensa_boletines.html."},{"key":"10.1016\/j.medcli.2009.09.002_bib27","unstructured":"Espa\u00f1a. Ministerio de Sanidad y Pol\u00edtica Social. Casos humanos de infecci\u00f3n por el nuevo virus de la gripe A (H1N1). Evoluci\u00f3n de la infecci\u00f3n en Espa\u00f1a. Datos actualizados a 6 de julio de 2009. Madrid [consultado 9\/7\/2009]. Disponible en: http:\/\/www.msc.es\/profesionales\/saludPublica\/gripeA\/docs\/actualizacion_casos_confirmados_060709_15h.pdf"},{"key":"10.1016\/j.medcli.2009.09.002_bib28","doi-asserted-by":"crossref","first-page":"814","DOI":"10.3201\/eid0808.010474","article-title":"Serologic evidence of H1 swine influenza virus infection in swine farm residents and employees","volume":"8","author":"Olsen","year":"2002","journal-title":"Emerg Infect Dis"},{"issue":"Suppl","key":"10.1016\/j.medcli.2009.09.002_bib29","doi-asserted-by":"crossref","first-page":"S386","DOI":"10.1093\/infdis\/136.Supplement_3.S386","article-title":"Swine influenza virus infections in humans","volume":"136","author":"Dowdle","year":"1977","journal-title":"J Infect Dis"},{"key":"10.1016\/j.medcli.2009.09.002_bib30","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1051\/vetres:2006062","article-title":"Avian and swine influenza viruses: our current understanding of the zoonotic risk","volume":"38","author":"Van Reeth","year":"2007","journal-title":"Vet Res"},{"key":"10.1016\/j.medcli.2009.09.002_bib31","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1086\/512813","article-title":"Cases of swine influenza in humans: a review of the literature","volume":"44","author":"Myers","year":"2007","journal-title":"CID"},{"key":"10.1016\/j.medcli.2009.09.002_bib32","doi-asserted-by":"crossref","first-page":"2616","DOI":"10.1056\/NEJMoa0903812","article-title":"Triple-reassortant swine influenza A (H1) in humans in the United States, 2005\u20132009","volume":"360","author":"Shinde","year":"2009","journal-title":"N Engl J Med"},{"key":"10.1016\/j.medcli.2009.09.002_bib33","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1007\/s11262-007-0097-9","article-title":"Genetic analysis of two influenza A (H1) swine viruses isolated from humans in Thailand and the Philippines","volume":"35","author":"Komadina","year":"2007","journal-title":"Virus Genes"},{"key":"10.1016\/j.medcli.2009.09.002_bib34","doi-asserted-by":"crossref","first-page":"23","DOI":"10.3201\/eid1201.050965","article-title":"Swine influenza A outbreak, Fort Dix, New Jersey, 1976","volume":"12","author":"Gaydos","year":"2006","journal-title":"Emerg Infect Dis"},{"key":"10.1016\/j.medcli.2009.09.002_bib35","doi-asserted-by":"crossref","first-page":"40","DOI":"10.3201\/eid1201.051132","article-title":"The swine flu episode and the fog of epidemics","volume":"12","author":"Krause","year":"2006","journal-title":"Emerg Infect Dis"},{"key":"10.1016\/j.medcli.2009.09.002_bib36","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1093\/oxfordjournals.aje.a112795","article-title":"Guillain-Barre syndrome following vaccination in the National Influenza Immunization Program, United States, 1976\u20131977","volume":"110","author":"Schonberger","year":"1979","journal-title":"Am J Epidemiol"},{"key":"10.1016\/j.medcli.2009.09.002_bib37","doi-asserted-by":"crossref","unstructured":"Adiego Sancho B, Omenaca Teres M, Martinez Cuenca S, Rodrigo Val P, Sanchez Villanueva P, Casas I, et al. Human case of swine influenza A (H1N1), Aragon, Spain, November 2008. Eurosurveillance. 2009;14(7):pii=19120 [consultado 18\/6\/2009]. Disponible en: http:\/\/www.eurosurveillance.org\/Viewarticle.aspx?articleId=19120","DOI":"10.2807\/ese.14.07.19120-en"},{"key":"10.1016\/j.medcli.2009.09.002_bib38","doi-asserted-by":"crossref","first-page":"1122","DOI":"10.1038\/nature08182","article-title":"Origins and evolutionary genomics of the 2009 swine-origin H1N1 influenza A epidemic","volume":"459","author":"Smith","year":"2009","journal-title":"Nature"},{"key":"10.1016\/j.medcli.2009.09.002_bib39","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1038\/nature08157","article-title":"Emergence and pandemic potential of swine-origin H1N1 influenza virus","volume":"459","author":"Neumann","year":"2009","journal-title":"Nature"},{"key":"10.1016\/j.medcli.2009.09.002_bib40","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/S0378-1135(00)00164-4","article-title":"The epidemiology and evolution of infuenza viruses in pigs","volume":"74","author":"Brown","year":"2000","journal-title":"Veterinary Microbiology"},{"key":"10.1016\/j.medcli.2009.09.002_bib41","doi-asserted-by":"crossref","first-page":"5485","DOI":"10.1128\/JVI.02565-08","article-title":"Different evolutionary trajectories of European avian-like and classical swine influenza A viruses","volume":"83","author":"Dunham","year":"2009","journal-title":"J Virol"},{"key":"10.1016\/j.medcli.2009.09.002_bib42","first-page":"521","article-title":"Serum cross-reactive antibody response to a novel influenza A (H1N1) virus after vaccination with seasonal influenza vaccine","volume":"58","year":"2009","journal-title":"MMWR"},{"key":"10.1016\/j.medcli.2009.09.002_bib43","doi-asserted-by":"crossref","unstructured":"Nishiura H, Castillo-Chavez C, Safan M, Chowell G. Transmission potential of the new influenza A (H1N1) virus and its age-specificity in Japan. Euro Surveill. 2009;14(22):pii=19227 [consultado 23\/6\/2009]. Disponible en: http:\/\/www.eurosurveillance.org\/ViewArticle.aspx?ArticleId=19227.WHO","DOI":"10.2807\/ese.14.22.19227-en"},{"key":"10.1016\/j.medcli.2009.09.002_bib44","doi-asserted-by":"crossref","first-page":"1557","DOI":"10.1126\/science.1176062","article-title":"Pandemic potential of a strain of Influenza A (H1N1): early findings","volume":"324","author":"Fraser","year":"2009","journal-title":"Science"},{"key":"10.1016\/j.medcli.2009.09.002_bib45","first-page":"470","article-title":"Swine-origin influenza A (H1N1) virus infections in a school\u2013New York City, April 2009","volume":"58","year":"2009","journal-title":"MMWR"},{"key":"10.1016\/j.medcli.2009.09.002_bib46","first-page":"197","article-title":"Considerations for assessing the severity of an influenza pandemic","volume":"84","year":"2009","journal-title":"WER"},{"key":"10.1016\/j.medcli.2009.09.002_bib47","doi-asserted-by":"crossref","unstructured":"Bo\u00eblle PY, Bernillon P, Desenclos JC. A preliminary estimation of the reproduction ratio for new influenza A (H1N1) from the outbreak in Mexico, March\u2013April 2009. Eurosurveillance. 2009;14(19):pii=19205 [consultado 24\/6\/2009]. Disponible en: http:\/\/www.eurosurveillance.org\/ViewArticle.aspx?ArticleId=19205","DOI":"10.2807\/ese.14.19.19205-en"},{"key":"10.1016\/j.medcli.2009.09.002_bib48","doi-asserted-by":"crossref","first-page":"852","DOI":"10.1017\/S0950268807009144","article-title":"Seasonal influenza in the United States, France, and Australia: transmission and prospects for control","volume":"136","author":"Chowell","year":"2008","journal-title":"Epidemiol Infect"},{"key":"10.1016\/j.medcli.2009.09.002_bib49","first-page":"185","article-title":"Human infection with new influenza A (H1N1) virus: clinical observations from Mexico and other affected countries, May 2009","volume":"84","year":"2009","journal-title":"WER"},{"key":"10.1016\/j.medcli.2009.09.002_bib50","doi-asserted-by":"crossref","first-page":"B2840","DOI":"10.1136\/bmj.b2840","article-title":"Assessing the severity of the novel influenza A\/H1N1 pandemic","volume":"339","author":"Garske","year":"2009","journal-title":"BMJ"},{"key":"10.1016\/j.medcli.2009.09.002_bib51","doi-asserted-by":"crossref","DOI":"10.1056\/NEJMoa0904252","article-title":"Pneumonia and respiratory failure from swine-origin influenza A (H1N1) in Mexico","author":"Perez-Padilla","year":"2009","journal-title":"N Engl J Med"},{"key":"10.1016\/j.medcli.2009.09.002_bib52","doi-asserted-by":"crossref","DOI":"10.1056\/NEJMoa0904023","article-title":"Severe respiratory disease concurrent with the circulation of H1N1 influenza","author":"Chowell","year":"2009","journal-title":"N Engl J Med"},{"key":"10.1016\/j.medcli.2009.09.002_bib53","unstructured":"CDC. 2008\u20132009 Influenza Season, Week 22 ending June 6, 2009. CDC, 12 June 2009 [consultado 22\/6\/2009]. Disponible en: http:\/\/www.cdc.gov\/flu\/weekly\/"},{"key":"10.1016\/j.medcli.2009.09.002_bib54","unstructured":"Ministerio de Salud. Chile. Nueva Influenza A-H1N1: Pr\u00f3ximo lunes comienza etapa de mitigaci\u00f3n. 27 Mayo 2009 [consultado 24\/6\/2009]. Disponible en: http:\/\/www.redsalud.gov.cl\/noticias\/noticias.php?id_n=445&show=5-2009"},{"key":"10.1016\/j.medcli.2009.09.002_bib55","unstructured":"M\u00e9xico. Situaci\u00f3n actual de la epidemia, 9 de junio de 2009. Estados Unidos Mexicanos, 2009 [consultado 18\/6\/2009]. Disponible en: http:\/\/portal.salud.gob.mx\/contenidos\/sala_prensa\/sala_prensa_prensa\/sala_prensa_boletines.html"},{"key":"10.1016\/j.medcli.2009.09.002_bib56","unstructured":"ECDC working group on influenza A (H1N1)v. Analysis of influenza A (H1N1)v individual data in EU and EEAA\/EFTA countries [consultado 17\/6\/2009]. Disponible en: http:\/\/www.ecdc.europa.eu\/en\/files\/pdf\/Health_topics\/0906_Influenza_A(H1N1)_Analysis_of_individual_data_EU_EEA-EFTA.pdf"},{"key":"10.1016\/j.medcli.2009.09.002_bib57","first-page":"185","article-title":"Human infection with new influenza A (H1N1) virus: clinical observations from Mexico and other affected countries, May 2009","volume":"84","year":"2009","journal-title":"WER"},{"key":"10.1016\/j.medcli.2009.09.002_bib58","unstructured":"Minist\u00e9rio da Sa\u00fade. Brasil. Ocorr\u00eancias de casos humanos de infec\u00e7\u00e3o por Influenza A (H1N1). Informe do dia 15.07.09, \u00e0s 16h. Gabinete Permanente de Emerg\u00eancias de Sa\u00fade P\u00fablica [consultado 17\/7\/2009]. Disponible en: http:\/\/portal.saude.gov.br\/portal\/arquivos\/pdf\/InfluenzaAH1N115julho2009.pdf"},{"key":"10.1016\/j.medcli.2009.09.002_bib59","first-page":"749","article-title":"Intensive-care patients with severe novel influenza A (H1N1) virus infections\u2013Michigan, June 2009","volume":"58","year":"2009","journal-title":"MMWR"},{"key":"10.1016\/j.medcli.2009.09.002_bib60","first-page":"497","article-title":"Novel influenza A (H1N1) virus infections in three pregnant women-United States, April\u2013May 2009","volume":"58","year":"2009","journal-title":"MMWR"},{"key":"10.1016\/j.medcli.2009.09.002_bib61","doi-asserted-by":"crossref","first-page":"95","DOI":"10.3201\/eid1401.070667","article-title":"Pandemic influenza and pregnant women","volume":"14","author":"Rasmussen","year":"2008","journal-title":"Emerg Infect Dis"},{"key":"10.1016\/j.medcli.2009.09.002_bib62","doi-asserted-by":"crossref","first-page":"D45","DOI":"10.1016\/j.vaccine.2008.07.066","article-title":"Epidemiology of influenza","volume":"206","author":"Monto","year":"2008","journal-title":"Vaccine"},{"key":"10.1016\/j.medcli.2009.09.002_bib63","doi-asserted-by":"crossref","unstructured":"Itoh Y, Shinya K, Kiso M, Watanabe T, Sakoda Y, Hatta M, et al. In vitro and in vivo characterization of new swine-origin H1N1 influenza viruses. Nature. 2009 [consultado 16\/7\/2009]. Disponible en: http:\/\/www.nature.com\/nature\/journal\/vaop\/ncurrent\/index.html [en prensa]","DOI":"10.1038\/nature08260"},{"key":"10.1016\/j.medcli.2009.09.002_bib64","doi-asserted-by":"crossref","first-page":"1254","DOI":"10.1086\/598989","article-title":"Influenza virus resistance to antiviral agents: a plea for rational use","volume":"48","author":"Poland","year":"2009","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.medcli.2009.09.002_bib65","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1056\/NEJM200302273480923","article-title":"Prolonged shedding of multidrug-resistant influenza A virus in an immunocompromised patient","volume":"348","author":"Weinstock","year":"2003","journal-title":"N Engl J Med"},{"key":"10.1016\/j.medcli.2009.09.002_bib66","unstructured":"WHO. Gene sequences of the reassortant candidate vaccine viruses for the novel influenza. 5 June 2009 [consultado 12\/6\/2009]. Disponible en: http:\/\/www.who.int\/csr\/resources\/publications\/swineflu\/gene_sequences\/en\/index.html."}],"container-title":["Medicina Cl\u00ednica"],"original-title":[],"language":"es","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0025775309012354?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0025775309012354?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,5,26]],"date-time":"2023-05-26T22:41:19Z","timestamp":1685140879000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0025775309012354"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,10]]},"references-count":66,"journal-issue":{"issue":"13","published-print":{"date-parts":[[2009,10]]}},"alternative-id":["S0025775309012354"],"URL":"https:\/\/doi.org\/10.1016\/j.medcli.2009.09.002","relation":{},"ISSN":["0025-7753"],"issn-type":[{"value":"0025-7753","type":"print"}],"subject":[],"published":{"date-parts":[[2009,10]]}}}