{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,9,13]],"date-time":"2023-09-13T20:51:30Z","timestamp":1694638290253},"reference-count":48,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2011,2,1]],"date-time":"2011-02-01T00:00:00Z","timestamp":1296518400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicina Cl\u00ednica"],"published-print":{"date-parts":[[2011,2]]},"DOI":"10.1016\/j.medcli.2009.11.013","type":"journal-article","created":{"date-parts":[[2009,12,31]],"date-time":"2009-12-31T09:07:46Z","timestamp":1262250466000},"page":"158-162","source":"Crossref","is-referenced-by-count":5,"title":["La cistatina C: una prote\u00edna para la insuficiencia card\u00edaca"],"prefix":"10.1016","volume":"136","author":[{"given":"Juan Ignacio","family":"P\u00e9rez-Calvo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 Luis","family":"Morales Rull","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francisco Jos\u00e9","family":"Ruiz Ruiz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.medcli.2009.11.013_bib1","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1152\/physiolgenomics.2001.7.2.95","article-title":"Further defining housekeeping, or \u201cmaintenance,\u201d genes Focus on \u201cA compendium of gene expression in normal human tissues\u201d","volume":"7","author":"Butte","year":"2001","journal-title":"Physiol Genomics"},{"key":"10.1016\/j.medcli.2009.11.013_bib2","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1016\/j.tig.2008.08.004","article-title":"On the nature of human housekeeping genes","volume":"24","author":"Zhu","year":"2008","journal-title":"Trends Genet"},{"key":"10.1016\/j.medcli.2009.11.013_bib3","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1038\/70487","article-title":"Analysis of human transcriptomes","volume":"23","author":"Velculescu","year":"1999","journal-title":"Nat Genet"},{"key":"10.1016\/j.medcli.2009.11.013_bib4","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1016\/S0168-9525(03)00140-9","article-title":"Human housekeeping genes are compact","volume":"19","author":"Eisenberg","year":"2003","journal-title":"Trends Genet"},{"key":"10.1016\/j.medcli.2009.11.013_bib5","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/0014-5793(91)80804-C","article-title":"The cystatins: Protein inhibitors of cysteine proteinases","volume":"285","author":"Turk","year":"1991","journal-title":"FEBS Lett"},{"key":"10.1016\/j.medcli.2009.11.013_bib6","doi-asserted-by":"crossref","first-page":"5691","DOI":"10.1021\/bi00319a005","article-title":"Isolation of a human cDNA for a-thiol proteinase inhibitor and its identity with low mo-lecular weight kininogen","volume":"23","author":"Ohkubo","year":"1984","journal-title":"Biochemistry"},{"key":"10.1016\/j.medcli.2009.11.013_bib7","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1210\/en.2002-220997","article-title":"The cystatin-related epididymal spermatogenic protein inhibits the serine protease prohormone convertase 2","volume":"144","author":"Cornwall","year":"2003","journal-title":"Endocrinology"},{"key":"10.1016\/j.medcli.2009.11.013_bib8","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/0014-5793(87)80695-6","article-title":"Molecular cloning and sequence analysis of cDNA coding for the precursor of the human cysteine proteinase inhibitor cystatin C","volume":"216","author":"Abrahamson","year":"1987","journal-title":"FEBS Lett"},{"key":"10.1016\/j.medcli.2009.11.013_bib9","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1042\/bj2680287","article-title":"Structure and expression of the human cystatin C gene","volume":"268","author":"Abrahamson","year":"1990","journal-title":"Biochem J"},{"key":"10.1016\/j.medcli.2009.11.013_bib10","doi-asserted-by":"crossref","first-page":"11282","DOI":"10.1016\/S0021-9258(18)67380-6","article-title":"Isolation of six cysteine proteinase inhibitors from human urine. Their physicochemical and enzyme kinetic properties and concentrations in biological fluids","volume":"261","author":"Abrahamson","year":"1986","journal-title":"J Biol Chem"},{"key":"10.1016\/j.medcli.2009.11.013_bib11","doi-asserted-by":"crossref","first-page":"3024","DOI":"10.1073\/pnas.79.9.3024","article-title":"Human gamma-trace, a basic microprotein: Amino acid sequence and presence in the adenohypophysis","volume":"79","author":"Grubb","year":"1982","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.medcli.2009.11.013_bib12","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1084\/jem.158.2.623","article-title":"Amyloid fibril in hereditary cerebral hemorrhage with amyloidosis (HCHWA) is related to the gastroentero-pancreatic neuroendocrine protein, gamma trace","volume":"158","author":"Cohen","year":"1983","journal-title":"J Exp Med"},{"key":"10.1016\/j.medcli.2009.11.013_bib13","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1172\/JCI7709","article-title":"Cystatin C deficiency in human atherosclerosis and aortic aneurysms","volume":"104","author":"Shi","year":"1999","journal-title":"J Clin Invest"},{"key":"10.1016\/j.medcli.2009.11.013_bib14","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1161\/01.RES.0000155964.34150.F7","article-title":"Cystatin C deficiency increases elastic lamina degradation and aortic dilatation in apolipoprotein E-null mice","volume":"96","author":"Sukhova","year":"2005","journal-title":"Circ Res"},{"key":"10.1016\/j.medcli.2009.11.013_bib15","doi-asserted-by":"crossref","first-page":"1933","DOI":"10.1093\/clinchem\/38.10.1933","article-title":"Serum creatinine as an index of renal function: New insights into old concepts","volume":"38","author":"Perrone","year":"1992","journal-title":"Clin Chem"},{"key":"10.1016\/j.medcli.2009.11.013_bib16","doi-asserted-by":"crossref","first-page":"959","DOI":"10.7326\/0003-4819-141-12-200412210-00013","article-title":"Clinical implications of estimating equations for glomerular filtration rate","volume":"141","author":"Stevens","year":"2004","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.medcli.2009.11.013_bib17","doi-asserted-by":"crossref","first-page":"461","DOI":"10.7326\/0003-4819-130-6-199903160-00002","article-title":"A more accurate method to estimate glomerular filtration rate from serum creatinine: A new prediction equation. Modification of Diet in Renal Disease Study Group","volume":"130","author":"Levey","year":"1999","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.medcli.2009.11.013_bib18","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1053\/ajkd.2003.50035","article-title":"Assessing renal function in cirrhotic patients: Problems and pitfalls","volume":"41","author":"Sherman","year":"2003","journal-title":"Am J Kidney Dis"},{"key":"10.1016\/j.medcli.2009.11.013_bib19","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1258\/000456303770367243","article-title":"Cystatin C improves the detection of mild renal dysfunction in older patients","volume":"40","author":"O\u2019Riordan","year":"2003","journal-title":"Ann Clin Biochem"},{"key":"10.1016\/j.medcli.2009.11.013_bib20","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1053\/ajkd.2000.8237","article-title":"Serum cystatin C as a new marker for noninvasive estimation of glomerular filtration rate and as a marker for early renal impairment","volume":"36","author":"Coll","year":"2000","journal-title":"Am J Kidney Dis"},{"key":"10.1016\/j.medcli.2009.11.013_bib21","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1053\/ajkd.2001.20591","article-title":"Serum cystatin C concentration as a marker of renal dysfunction in the elderly","volume":"37","author":"Fliser","year":"2001","journal-title":"Am J Kidney Dis"},{"key":"10.1016\/j.medcli.2009.11.013_bib22","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1159\/000013564","article-title":"Cystatin C: Efficacy as screening test for reduced glomerular filtration rate","volume":"20","author":"Herget-Rosenthal","year":"2000","journal-title":"Am J Nephrol"},{"key":"10.1016\/j.medcli.2009.11.013_bib23","article-title":"Age and cystatin C in healthy adults: A collaborative study","volume":"11","author":"Odden","year":"2009","journal-title":"Nephrol Dial Transplant"},{"key":"10.1016\/j.medcli.2009.11.013_bib24","doi-asserted-by":"crossref","first-page":"1296","DOI":"10.1056\/NEJMoa041031","article-title":"Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization","volume":"351","author":"Go","year":"2004","journal-title":"N Engl J Med"},{"key":"10.1016\/j.medcli.2009.11.013_bib25","doi-asserted-by":"crossref","first-page":"2122","DOI":"10.1056\/NEJMe058035","article-title":"Chronic kidney disease in the elderly--how to assess risk","volume":"352","author":"Stevens","year":"2005","journal-title":"N Engl J Med"},{"key":"10.1016\/j.medcli.2009.11.013_bib26","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1161\/CIRCHEARTFAILURE.109.856393","article-title":"Serum cystatin C, renal filtration function, and Leith ventricular remodeling","volume":"2","author":"McMurray","year":"2009","journal-title":"Circ Heart Fail"},{"key":"10.1016\/j.medcli.2009.11.013_bib27","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1157\/13114561","article-title":"Cistatina C: \u00bfUn nuevo marcador de riesgo cardiovascular?","volume":"13","author":"M\u00e9ndez Bail\u00f3n","year":"2008","journal-title":"Med Clin (Barc)"},{"key":"10.1016\/j.medcli.2009.11.013_bib28","doi-asserted-by":"crossref","first-page":"2049","DOI":"10.1056\/NEJMoa043161","article-title":"Cystatin C and the risk of death and cardiovascular events among elderly persons","volume":"352","author":"Shlipak","year":"2005","journal-title":"N Engl J Med"},{"key":"10.1016\/j.medcli.2009.11.013_bib29","doi-asserted-by":"crossref","first-page":"497","DOI":"10.7326\/0003-4819-142-7-200504050-00008","article-title":"Cystatin C concentration as a risk factor for heart failure in older adults","volume":"142","author":"Sarnak","year":"2005","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.medcli.2009.11.013_bib30","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.ahj.2007.08.023","article-title":"Cystatin C and risk of heart failure in the Physicians\u2019 Health Study (PHS)","volume":"155","author":"Djouss\u00e9","year":"2008","journal-title":"Am Heart J"},{"key":"10.1016\/j.medcli.2009.11.013_bib31","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.cardfail.2007.09.002","article-title":"Concentration as a predictor of systolic and diastolic heart failure","volume":"14","author":"Moran","year":"2008","journal-title":"J Card Fail"},{"key":"10.1016\/j.medcli.2009.11.013_bib32","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1016\/j.amjhyper.2006.02.007","article-title":"Kidney function and systolic blood pressure new insights from cystatin C: Data from the Heart and Soul Study","volume":"19","author":"Peralta","year":"2006","journal-title":"Am J Hypertens"},{"key":"10.1016\/j.medcli.2009.11.013_bib33","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1016\/S0735-1097(99)00608-7","article-title":"The prognostic implications of renal insufficiency in asymptomatic and symptomatic patients with left ventricular systolic dysfunction","volume":"35","author":"Dries","year":"2000","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.medcli.2009.11.013_bib34","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.ahj.2007.08.012","article-title":"Kidney dysfunction and fatal cardiovascular disease--an association independent of atherosclerotic events: Results from the Health, Aging, and Body Composition (Health ABC) study","volume":"155","author":"Deo","year":"2008","journal-title":"Am Heart J"},{"key":"10.1016\/j.medcli.2009.11.013_bib35","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1016\/j.jacc.2004.09.061","article-title":"Cystatin-C and mortality in elderly persons with heart failure","volume":"45","author":"Shlipak","year":"2005","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.medcli.2009.11.013_bib36","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1016\/j.amjmed.2008.10.042","article-title":"Cystatin C in acute heart failure without advanced renal impairment","volume":"122","author":"Naruse","year":"2009","journal-title":"Am J Med"},{"key":"10.1016\/j.medcli.2009.11.013_bib37","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1016\/j.cardfail.2008.01.006","article-title":"Impact of myocardial function on cystatin C measurements in chronic systolic heart failure","volume":"14","author":"Tang","year":"2008","journal-title":"J Card Fail"},{"key":"10.1016\/j.medcli.2009.11.013_bib38","unstructured":"Carrasco J. Valor pron\u00f3stico de la cistatina C como biomarcador en la insuficiencia card\u00edaca cr\u00f3nica agudizada con funci\u00f3n sist\u00f3lica preservada y su relaci\u00f3n con otros factores pron\u00f3sticos cl\u00ednicos [tesis doctoral]. Huelva: Facultad de Ciencias Experimentales; 2009."},{"key":"10.1016\/j.medcli.2009.11.013_bib39","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1093\/eurjhf\/hfp024","article-title":"and NT-proBNP, a powerful combination of biomarkers for predicting cardiovascular mortality in elderly patients with heart failure: Results from a 10-year study in primary care","volume":"11","author":"Alehagen","year":"2009","journal-title":"Eur J Heart Fail"},{"key":"10.1016\/j.medcli.2009.11.013_bib40","doi-asserted-by":"crossref","first-page":"1753","DOI":"10.1016\/j.amjcard.2009.02.029","article-title":"Complementary prognostic value of cystatin C, N-terminal pro-B-type natriuretic Peptide and cardiac troponin T in patients with acute heart failure","volume":"103","author":"Manzano-Fern\u00e1ndez","year":"2009","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.medcli.2009.11.013_bib41","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1161\/01.HYP.0000169972.96201.8e","article-title":"Left ventricular hypertrophy is more prevalent in blacks than whites in the general population: The Dallas Heart Study","volume":"46","author":"Drazner","year":"2005","journal-title":"Hypertension"},{"key":"10.1016\/j.medcli.2009.11.013_bib42","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1161\/CIRCHEARTFAILURE.108.807271","article-title":"Association of Cystatin C with left ventricular structure and function: The Dallas Heart Study","volume":"2","author":"Patel","year":"2009","journal-title":"Circ Heart Fail"},{"key":"10.1016\/j.medcli.2009.11.013_bib43","doi-asserted-by":"crossref","first-page":"6234","DOI":"10.1073\/pnas.092637699","article-title":"Dilated cardiomyopathy in mice deficient for the lysosomal cysteine peptidase cathepsin","volume":"99","author":"Stypmann","year":"2002","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.medcli.2009.11.013_bib44","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1161\/01.HYP.0000242331.99369.2f","article-title":"Elastolytic cathepsin induction\/activation system exists in myocardium and is upregulated in hypertensive heart failure","volume":"48","author":"Cheng","year":"2006","journal-title":"Hypertension"},{"key":"10.1016\/j.medcli.2009.11.013_bib45","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1161\/01.HYP.0000242332.19693.e4","article-title":"Digesting the remodeled heart: Role of lysosomal cysteine proteases in heart failure","volume":"48","author":"Sam","year":"2006","journal-title":"Hypertension"},{"key":"10.1016\/j.medcli.2009.11.013_bib46","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.jacc.2006.01.077","article-title":"Alterations in the pattern of collagen deposition may contribute to the deterioration of systolic function in hypertensive patients with heart failure","volume":"48","author":"L\u00f3pez","year":"2006","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.medcli.2009.11.013_bib47","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.jacc.2006.04.004","article-title":"Extracellular matrix remodeling in hypertensive heart disease","volume":"48","author":"Shirwany","year":"2006","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.medcli.2009.11.013_bib48","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1161\/CIRCHEARTFAILURE.109.849299","article-title":"Prognostic value of biomarkers in heart failure. Application of novel methods in the community","volume":"2","author":"Dunlay","year":"2009","journal-title":"Circ Heart Fail"}],"container-title":["Medicina Cl\u00ednica"],"original-title":[],"language":"es","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0025775309015735?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0025775309015735?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,10,19]],"date-time":"2021-10-19T18:16:44Z","timestamp":1634667404000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0025775309015735"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,2]]},"references-count":48,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2011,2]]}},"alternative-id":["S0025775309015735"],"URL":"https:\/\/doi.org\/10.1016\/j.medcli.2009.11.013","relation":{},"ISSN":["0025-7753"],"issn-type":[{"value":"0025-7753","type":"print"}],"subject":[],"published":{"date-parts":[[2011,2]]}}}