{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,3]],"date-time":"2025-12-03T17:49:22Z","timestamp":1764784162427},"reference-count":49,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2019,4,1]],"date-time":"2019-04-01T00:00:00Z","timestamp":1554076800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.es","elsevier.es","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Medicina Cl\u00ednica"],"published-print":{"date-parts":[[2019,4]]},"DOI":"10.1016\/j.medcli.2018.10.013","type":"journal-article","created":{"date-parts":[[2018,12,1]],"date-time":"2018-12-01T02:08:56Z","timestamp":1543630136000},"page":"317-323","update-policy":"http:\/\/dx.doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"title":["Infecciones por Mycobacterium chimaera y cirug\u00eda card\u00edaca. Un problema no resuelto"],"prefix":"10.1016","volume":"152","author":[{"given":"Magda","family":"Campins Mart\u00ed","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Blanca","family":"Borr\u00e1s Bermejo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lluis","family":"Armadans Gil","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.medcli.2018.10.013_bib0250","doi-asserted-by":"crossref","first-page":"1277","DOI":"10.1099\/ijs.0.02777-0","article-title":"Proposal to elevate the genetic variant MAC-A, included in the Mycobacterium avium complex, to species rank as Mycobacterium chimaera sp. nov","volume":"54","author":"Tortoli","year":"2004","journal-title":"Int J Syst Evol Microbiol."},{"key":"10.1016\/j.medcli.2018.10.013_bib0255","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1016\/j.diagmicrobio.2008.12.002","article-title":"Molecular identification of Mycobacterium chimaera as a cause of infection in a patient with chronic obstructive pulmonary disease","volume":"63","author":"Bills","year":"2009","journal-title":"Diagn Microbiol Infect Dis."},{"key":"10.1016\/j.medcli.2018.10.013_bib0260","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1186\/1752-1947-5-473","article-title":"Mycobacterium chimaera pulmonary infection complicating cystic fibrosis: A case report","volume":"5","author":"Cohen-Bacrie","year":"2011","journal-title":"J Med Case Rep."},{"key":"10.1016\/j.medcli.2018.10.013_bib0265","doi-asserted-by":"crossref","first-page":"1769","DOI":"10.1128\/JCM.00435-13","article-title":"Prosthetic valve endocarditis and bloodstream infection due to Mycobacterium chimaera","volume":"51","author":"Achermann","year":"2013","journal-title":"J Clin Microbiol."},{"key":"10.1016\/j.medcli.2018.10.013_bib0270","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1093\/cid\/civ198","article-title":"Prolonged outbreak of Mycobacterium chimaera infection after open-chest heart surgery","volume":"61","author":"Sax","year":"2015","journal-title":"Clin Infect Dis."},{"key":"10.1016\/j.medcli.2018.10.013_bib0275","doi-asserted-by":"crossref","first-page":"2745","DOI":"10.1093\/eurheartj\/ehv342","article-title":"Healthcare-associated prothestic heart valve, aortic vascular graft, and disseminated Mycobacterium chimaera infections subseq\u00fcent to open heart surgery","volume":"36","author":"Kohler","year":"2015","journal-title":"Eur Heart J."},{"key":"10.1016\/j.medcli.2018.10.013_bib0280","unstructured":"Public Health England. Mycobacterium chimaera: Infections linked to heater cooler units. May 31, 2017 [acceso 25 Jul 2018). Disponible en: https:\/\/www.gov.uk\/government\/news\/mycobacterial-infections-associated-with-cardiopulmonary-bypass-surgery"},{"key":"10.1016\/j.medcli.2018.10.013_bib0285","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/j.jhin.2016.02.006","article-title":"Heater-cooler units: Contamination of crucial devices in cardiothoracic surgery","volume":"93","author":"G\u00f6tting","year":"2016","journal-title":"J Hosp Infect."},{"key":"10.1016\/j.medcli.2018.10.013_bib0290","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.15585\/mmwr.mm6540a6","article-title":"Notes from the field: Mycobacterium chimaera contamination of heater-cooler devices used in cardiac surgery - United States","volume":"65","author":"Perkins","year":"2016","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"10.1016\/j.medcli.2018.10.013_bib0295","doi-asserted-by":"crossref","DOI":"10.1093\/ofid\/ofw131","article-title":"Disseminated Mycobacterium chimaera infection after cardiothoracic surgery","volume":"3","author":"Tan","year":"2016","journal-title":"Open Forum Infect Dis."},{"key":"10.1016\/j.medcli.2018.10.013_bib0300","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1056\/NEJMc1612023","article-title":"Mycobacterium chimaera spread from heating and cooling units in heart surgery","volume":"376","author":"Williamson","year":"2017","journal-title":"N Engl J Med."},{"key":"10.1016\/j.medcli.2018.10.013_bib0305","doi-asserted-by":"crossref","first-page":"13","DOI":"10.3201\/eid2206.160045","article-title":"Transmission of Mycobacterium chimaera from heater-cooler units during cardiac surgery despite an ultraclean air ventilation System","volume":"22","author":"Sommerstein","year":"2016","journal-title":"Emerg Infect Dis."},{"key":"10.1016\/j.medcli.2018.10.013_bib0310","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/j.jhin.2017.04.014","article-title":"Microbiological problems and biofilms associated with Mycobacterium chimaera in heater-cooler units used for cardiopulmonary bypass","volume":"96","author":"Walker","year":"2017","journal-title":"J Hosp Infect."},{"key":"10.1016\/j.medcli.2018.10.013_bib0315","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1017\/ice.2018.102","article-title":"Different types of heater-cooler units and their risk of transmission of Mycobacterium chimaera during open-heart surgery: Clues from device design","volume":"39","author":"Kuehl","year":"2018","journal-title":"Infect Control Hosp Epidemiol."},{"key":"10.1016\/j.medcli.2018.10.013_bib0320","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1136\/thx.27.4.395","article-title":"Infections through blood from heart-lung machine","volume":"27","author":"Geldof","year":"1972","journal-title":"Thorax."},{"key":"10.1016\/j.medcli.2018.10.013_bib0325","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1177\/026765910001500108","article-title":"A retrospective study on perfusion incidents and safety devices","volume":"15","author":"Mejak","year":"2000","journal-title":"Perfusion."},{"key":"10.1016\/j.medcli.2018.10.013_bib0330","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1017\/ice.2016.283","article-title":"Mycobacterium chimaera outbreak associated with heater-cooler devices: Piecing the puzzle together","volume":"38","author":"Sommerstein","year":"2017","journal-title":"Infect Control Hosp Epidemiol."},{"key":"10.1016\/j.medcli.2018.10.013_bib0335","doi-asserted-by":"crossref","first-page":"30215","DOI":"10.2807\/1560-7917.ES.2016.21.17.30215","article-title":"Contamination during production of heater-cooler units by Mycobacterium chimaera potential cause for invasive cardiovascular infections: Results of an outbreak investigation in Germany April 2015 to February 2016","volume":"21","author":"Haller","year":"2016","journal-title":"Euro Surveill."},{"key":"10.1016\/j.medcli.2018.10.013_bib0340","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1016\/S1473-3099(17)30324-9","article-title":"Global outbreak of severe Mycobacterium chimaera disease after cardiac surgery: A molecular epidemiological study","volume":"17","author":"Van Ingen","year":"2017","journal-title":"Lancet Infect Dis."},{"key":"10.1016\/j.medcli.2018.10.013_bib0345","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1093\/cid\/cix368","article-title":"Mycobacterium chimaera infections associated with contaminated heater-cooler devices for cardiac surgery: Outbreak management","volume":"65","author":"Marra","year":"2017","journal-title":"Clin Infect Dis."},{"key":"10.1016\/j.medcli.2018.10.013_bib0350","doi-asserted-by":"crossref","first-page":"1164","DOI":"10.1016\/j.cmi.2018.04.027","article-title":"Mycobacterium chimaera infection following cardiac surgery in the United Kingdom: Clinical features and outcome of the first 30 cases","volume":"24","author":"Scriven","year":"2018","journal-title":"Clin Microbiol Infect."},{"key":"10.1016\/j.medcli.2018.10.013_bib0355","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.idcr.2016.10.010","article-title":"Persistent immune thrombocytopenia heralds the diagnosis of Mycobacterium chimaera prosthetic valve endocarditis","volume":"7","author":"Sacco","year":"2017","journal-title":"IDCases."},{"key":"10.1016\/j.medcli.2018.10.013_bib0360","doi-asserted-by":"crossref","first-page":"1237","DOI":"10.1016\/j.athoracsur.2017.04.067","article-title":"Nontuberculous Mycobacterium infections associated with heater-cooler devices","volume":"104","author":"Allen","year":"2017","journal-title":"Ann Thorac Surg."},{"key":"10.1016\/j.medcli.2018.10.013_bib0365","doi-asserted-by":"crossref","first-page":"107","DOI":"10.14745\/ccdr.v43i05a05","article-title":"Mycobacterium chimaera infections in post-operative patients exposed to heater-cooler devices: An overview","volume":"43","author":"Ogunremi","year":"2017","journal-title":"Can Commun Dis Rep."},{"key":"10.1016\/j.medcli.2018.10.013_bib0370","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.idh.2017.01.003","article-title":"First Australian case of disseminated Mycobacterium chimaera infection post-cardiothoracic surgery","volume":"22","author":"Bursle","year":"2017","journal-title":"Infect Dis Heal."},{"key":"10.1016\/j.medcli.2018.10.013_bib0375","first-page":"267","article-title":"Disseminated Mycobacterium chimaera infection after open heart surgery in an Italian woman: A case report and a review of the literature","volume":"25","author":"Chiesi","year":"2017","journal-title":"Infez Med."},{"key":"10.1016\/j.medcli.2018.10.013_bib0380","doi-asserted-by":"crossref","first-page":"796","DOI":"10.3201\/eid2305.161899","article-title":"Invasive nontuberculous mycobacterial infections among cardiothoracic surgical patients exposed to heater\u2013cooler devices","volume":"23","author":"Lyman","year":"2017","journal-title":"Emerg Infect Dis."},{"key":"10.1016\/j.medcli.2018.10.013_bib0385","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/j.ophtha.2016.09.032","article-title":"Clinical and histopathologic ocular findings in disseminated Mycobacterium chimaera infection after cardiothoracic surgery","volume":"124","author":"Zweifel","year":"2017","journal-title":"Ophthalmology."},{"key":"10.1016\/j.medcli.2018.10.013_bib0390","doi-asserted-by":"crossref","first-page":"2369","DOI":"10.1016\/j.jtcvs.2017.12.049","article-title":"Disseminated Mycobacterium chimaera infection associated with heater-cooler units after aortic valve surgery without endocarditis","volume":"155","author":"Asadi","year":"2018","journal-title":"J Thorac Cardiovasc Surg."},{"key":"10.1016\/j.medcli.2018.10.013_bib0395","unstructured":"ECDC. EU protocol for case detection, laboratory diagnosis and environmental testing of Mycobacterium chimaera infections potentially associated with heater-cooler units: case definition and environmental testing methodology. August 2015 [acceso 25 Jul 2018]. Disponible en: https:\/\/ecdc.europa.eu\/sites\/portal\/files\/media\/en\/publications\/Publications\/EU-protocol-for-M-chimaera.pdf"},{"key":"10.1016\/j.medcli.2018.10.013_bib0400","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1016\/j.cmi.2017.07.031","article-title":"Comparison of methods available for identification of Mycobacterium chimaera","volume":"24","author":"Lecorche","year":"2018","journal-title":"Clin Microbiol Infect."},{"key":"10.1016\/j.medcli.2018.10.013_bib0405","doi-asserted-by":"crossref","first-page":"1307","DOI":"10.1099\/jmm.0.000359","article-title":"Frequency of Mycobacterium chimaera among Belgian patients, 2015","volume":"65","author":"Soetaert","year":"2016","journal-title":"J Med Microbiol."},{"key":"10.1016\/j.medcli.2018.10.013_bib0410","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1007\/s12630-016-0809-5","article-title":"Mycobacterium infection from a cardiopulmonary bypass heater-cooler unit in a patient with steroid-induced immunosuppression","volume":"64","author":"Cai","year":"2017","journal-title":"Can J Anesth."},{"key":"10.1016\/j.medcli.2018.10.013_bib0415","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1164\/rccm.200604-571ST","article-title":"An official ATS\/IDSA statement: Diagnosis, treatment, and prevention of nontuberculous mycobacterial diseases","volume":"175","author":"Griffith","year":"2007","journal-title":"Am J Respir Crit Care Med."},{"key":"10.1016\/j.medcli.2018.10.013_bib0420","unstructured":"Public Health England. Infections associated with heater cooler units used in cardiopulmonary bypass and ECMO: Information for healthcare providers in the UK, version 2 London: Public Health England; 2017."},{"key":"10.1016\/j.medcli.2018.10.013_bib0425","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1093\/cid\/ciw754","article-title":"Insidious risk of severe Mycobacterium chimaera infection in cardiac surgery patients","volume":"64","author":"Chand","year":"2017","journal-title":"Clin Infect Dis."},{"key":"10.1016\/j.medcli.2018.10.013_bib0430","unstructured":"Interim guide for the identification of possible cases of nontuberculous Mycobacterium infections associated with exposure to heater-cooler units - CDC - May 13, 2016."},{"key":"10.1016\/j.medcli.2018.10.013_bib0435","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1177\/0267659117700489","article-title":"Elimination of Mycobacterium chimaera in a heater cooler device used during on-pump cardiothoracic surgery","volume":"32","author":"Nielsen","year":"2017","journal-title":"Perfusion."},{"key":"10.1016\/j.medcli.2018.10.013_bib0440","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/j.jhin.2016.02.007","article-title":"Decontamination of heater-cooler units associated with contamination by atypical mycobacteria","volume":"93","author":"Garvey","year":"2016","journal-title":"J Hosp Infect."},{"key":"10.1016\/j.medcli.2018.10.013_bib0445","doi-asserted-by":"crossref","first-page":"3","DOI":"10.3201\/eid2210.160925","article-title":"Reemergence of Mycobacterium chimaera in heater-cooler units despite intensified cleaning and disinfection protocol","volume":"22","author":"Schreiber","year":"2016","journal-title":"Emerg Infect Dis."},{"key":"10.1016\/j.medcli.2018.10.013_bib0450","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1017\/ice.2017.64","article-title":"A year in the life of a contaminated heater-cooler unit with Mycobacterium chimaera?","volume":"38","author":"Garvey","year":"2017","journal-title":"Infect Control Hosp Epidemiol."},{"key":"10.1016\/j.medcli.2018.10.013_bib0455","unstructured":"European Centre for Disease Prevention and Control. EU protocol for case detection, laboratory diagnosis and infections potentially associated with heater-cooler units: Multi-country outbreak of Mycobacterium chimaera infections Retrospective case identification Case definition. Stockholm: ECDC; 2015."},{"key":"10.1016\/j.medcli.2018.10.013_bib0460","article-title":"Protocol for environmental sampling, processing and culturing of water and air samples for the isolation of slow-growing mycobacteria standard operating procedure. PHE publications gateway number: 2016150 2 Protocol for Environmental Sampling Processing a","author":"Kranzer","year":"2018","journal-title":"Public Health England"},{"key":"10.1016\/j.medcli.2018.10.013_bib0465","unstructured":"US Food and Drug Administration. Heater-cooler devices - Information for health care providers and staff at health care facilities [Internet]. U.S. Food and Drug Administration; [citado 8 Jul 2018]. Disponible en: https:\/\/www.fda.gov\/MedicalDevices\/ProductsandMedicalProcedures\/CardiovascularDevices\/Heater-CoolerDevices\/ucm492583.htm"},{"key":"10.1016\/j.medcli.2018.10.013_bib0470","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1016\/j.jhin.2017.11.007","article-title":"Detection limit of Mycobacterium chimaera in water samples for monitoring medical device safety: insights from a pilot experimental series","volume":"99","author":"Schreiber","year":"2018","journal-title":"J Hosp Infect."},{"key":"10.1016\/j.medcli.2018.10.013_bib0475","unstructured":"European Centre for Disease Prevention and Control. Invasive cardiovascular infection by Mycobacterium chimaera associated with 3T heater -cooler system used during open-heart surgery \u2013 18 November 2016. Stockholm: ECDC; 2016."},{"key":"10.1016\/j.medcli.2018.10.013_bib0480","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1016\/j.jhin.2016.03.026","article-title":"Cardiac surgery, nosocomial infection, and the built environment","volume":"93","author":"Sommerstein","year":"2016","journal-title":"J Hosp Infect."},{"key":"10.1016\/j.medcli.2018.10.013_bib0485","unstructured":"Sorin Group. 3T Instructions for use - Aerosol Collection Set. 2017 [citado 8 Jul 2018]. Disponible en: http:\/\/www.livanova.sorin.com\/products\/cardiac-surgery\/perfusion\/hlm\/3t-out-us"},{"key":"10.1016\/j.medcli.2018.10.013_bib0490","doi-asserted-by":"crossref","first-page":"132","DOI":"10.5694\/mja16.00670","article-title":"Mycobacterium chimaera and cardiac surgery","volume":"206","author":"Stewardson","year":"2017","journal-title":"Med J Aust."}],"container-title":["Medicina Cl\u00ednica"],"original-title":[],"language":"es","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0025775318306390?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0025775318306390?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,4,1]],"date-time":"2019-04-01T08:53:59Z","timestamp":1554108839000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0025775318306390"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,4]]},"references-count":49,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2019,4]]}},"alternative-id":["S0025775318306390"],"URL":"https:\/\/doi.org\/10.1016\/j.medcli.2018.10.013","relation":{},"ISSN":["0025-7753"],"issn-type":[{"value":"0025-7753","type":"print"}],"subject":[],"published":{"date-parts":[[2019,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Infecciones por Mycobacterium chimaera y cirug\u00eda card\u00edaca. Un problema no resuelto","name":"articletitle","label":"Article Title"},{"value":"Medicina Cl\u00ednica","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.medcli.2018.10.013","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Espa\u00f1a, S.L.U. All rights reserved.","name":"copyright","label":"Copyright"}]}}