{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T04:31:29Z","timestamp":1769574689180,"version":"3.49.0"},"reference-count":61,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.es","elsevier.es","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Medicina Cl\u00ednica"],"published-print":{"date-parts":[[2025,9]]},"DOI":"10.1016\/j.medcli.2025.107107","type":"journal-article","created":{"date-parts":[[2025,7,17]],"date-time":"2025-07-17T12:19:21Z","timestamp":1752754761000},"page":"107107","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["S\u00edncope auton\u00f3mico"],"prefix":"10.1016","volume":"165","author":[{"given":"Jaume","family":"Francisco-Pascual","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jose Manuel","family":"Medina Magui\u00f1a","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nuria","family":"Rivas-G\u00e1ndara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.medcli.2025.107107_bib0320","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1093\/eurheartj\/ehae907","article-title":"Mechanism of syncope: Role of ambulatory blood pressure monitoring and cardiovascular autonomic function assessment","volume":"46","author":"Groppelli","year":"2025","journal-title":"Eur Heart J"},{"key":"10.1016\/j.medcli.2025.107107_bib0325","doi-asserted-by":"crossref","first-page":"euad155","DOI":"10.1093\/europace\/euad155","article-title":"Advancing the science of management of arrhythmic disease in children and adult congenital heart disease patients within the last 25 years","volume":"25","author":"Paul","year":"2023","journal-title":"EP Europace"},{"key":"10.1016\/j.medcli.2025.107107_bib0330","doi-asserted-by":"crossref","DOI":"10.1093\/europace\/euae073","article-title":"Mechanism-based therapy of non-cardiac syncope: A practical guide","volume":"26","author":"Brignole","year":"2024","journal-title":"Europace"},{"key":"10.1016\/j.medcli.2025.107107_bib0335","doi-asserted-by":"crossref","first-page":"euad163","DOI":"10.1093\/europace\/euad163","article-title":"Twenty-five years of research on syncope","volume":"25","author":"Fedorowski","year":"2023","journal-title":"Europace"},{"key":"10.1016\/j.medcli.2025.107107_bib0340","first-page":"e60","article-title":"2017 ACC\/AHA\/HRS guideline for the evaluation and management of patients with syncope: A report of the American college of cardiology\/American Heart Association task force on clinical practice guidelines and the Heart Rhythm Society","volume":"136","author":"Shen","year":"2017","journal-title":"Circulation"},{"key":"10.1016\/j.medcli.2025.107107_bib0345","doi-asserted-by":"crossref","first-page":"1883","DOI":"10.1093\/eurheartj\/ehy037","article-title":"2018 ESC Guidelines for the diagnosis and management of syncope","volume":"39","author":"Brignole","year":"2018","journal-title":"Eur Heart J"},{"key":"10.1016\/j.medcli.2025.107107_bib0350","doi-asserted-by":"crossref","first-page":"878","DOI":"10.1056\/NEJMoa012407","article-title":"Incidence and Prognosis of Syncope","volume":"347","author":"Soteriades","year":"2002","journal-title":"N Engl J Med"},{"key":"10.1016\/j.medcli.2025.107107_bib0355","doi-asserted-by":"crossref","first-page":"1896","DOI":"10.1093\/europace\/euaa246","article-title":"Frequency of injuries associated with syncope in the prevention of syncope trials","volume":"22","author":"Jorge","year":"2020","journal-title":"EP Europace"},{"key":"10.1016\/j.medcli.2025.107107_bib0360","doi-asserted-by":"crossref","first-page":"119","DOI":"10.4330\/wjc.v15.i4.119","article-title":"Arrhythmic syncope: From diagnosis to management","volume":"15","author":"Francisco Pascual","year":"2023","journal-title":"World J Cardiol"},{"key":"10.1016\/j.medcli.2025.107107_bib0365","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/j.ejim.2023.03.025","article-title":"Vasovagal syncope: An overview of pathophysiological mechanisms","volume":"112","author":"Longo","year":"2023","journal-title":"Eur J Intern Med"},{"key":"10.1016\/j.medcli.2025.107107_bib0370","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1152\/physrev.00007.2024","article-title":"Pathophysiology of syncope: Current concepts and their development","volume":"105","author":"Benditt","year":"2025","journal-title":"Physiol Rev"},{"key":"10.1016\/j.medcli.2025.107107_bib0375","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1093\/europace\/eul095","article-title":"The venous system is the main determinant of hypotension in patients with vasovagal syncope","volume":"8","author":"Fuc\u00e0","year":"2006","journal-title":"EP Europace"},{"key":"10.1016\/j.medcli.2025.107107_bib0380","doi-asserted-by":"crossref","first-page":"euae206","DOI":"10.1093\/europace\/euae206","volume":"26","author":"Aksu","year":"2024","journal-title":"Europace"},{"key":"10.1016\/j.medcli.2025.107107_bib0385","doi-asserted-by":"crossref","first-page":"e028704","DOI":"10.1161\/JAHA.122.028704","article-title":"Twenty-Four-Hour Ambulatory Blood Pressure Profile in Patients With Reflex Syncope and Matched Controls","volume":"12","author":"Sharad","year":"2023","journal-title":"J Am Heart Assoc"},{"key":"10.1016\/j.medcli.2025.107107_bib0390","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1093\/europace\/euaa070","article-title":"Plasma adenosine and neurally mediated syncope: Ready for clinical use","volume":"22","author":"Brignole","year":"2020","journal-title":"Europace"},{"key":"10.1016\/j.medcli.2025.107107_bib0395","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1080\/17434440.2023.2174428","article-title":"Tests for the identification of reflex syncope mechanism","volume":"20","author":"Brignole","year":"2023","journal-title":"Expert Rev Med Devices"},{"key":"10.1016\/j.medcli.2025.107107_bib0400","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1016\/j.medcli.2023.12.014","article-title":"S\u00edncope","volume":"162","author":"Francisco-Pascual","year":"2024","journal-title":"Med Clin (Barc)"},{"key":"10.1016\/j.medcli.2025.107107_bib0405","first-page":"284","article-title":"Syncope in Patients With Severe Aortic Stenosis: More Than Just an Obstruction Issue","volume":"37","author":"Francisco-Pascual","year":"2021","journal-title":"Can J Cardiol."},{"key":"10.1016\/j.medcli.2025.107107_bib0410","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1016\/j.hrthm.2020.12.009","article-title":"Etiology and prognosis of patients with unexplained syncope and mid-range left ventricular dysfunction","volume":"18","author":"Francisco-Pascual","year":"2021","journal-title":"Heart Rhythm"},{"key":"10.1016\/j.medcli.2025.107107_bib0415","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1016\/j.hrthm.2018.12.015","article-title":"Syncope, conduction disturbance, and negative electrophysiological test: Predictive factors and risk score to predict pacemaker implantation during follow-up","volume":"16","author":"Roca-Luque","year":"2019","journal-title":"Heart Rhythm"},{"key":"10.1016\/j.medcli.2025.107107_bib0420","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1007\/s00399-018-0560-4","article-title":"Syncope and bundle branch block: Diagnostic approach","volume":"29","author":"Moya","year":"2018","journal-title":"Herzschrittmacherther Elektrophysiol"},{"key":"10.1016\/j.medcli.2025.107107_bib0425","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1016\/j.jacep.2018.09.015","article-title":"Flecainide Versus Procainamide in Electrophysiological Study in Patients With Syncope and Wide QRS Duration","volume":"5","author":"Roca-Luque","year":"2019","journal-title":"JACC Clin Electrophysiol"},{"key":"10.1016\/j.medcli.2025.107107_bib0430","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1016\/j.recesp.2022.11.010","article-title":"Arrhythmic risk in single or recurrent episodes of unexplained syncope with complete bundle branch block [Article in English, Spanish]","volume":"76","author":"Francisco-Pascual","year":"2023","journal-title":"Rev Esp Cardiol (Engl Ed)"},{"key":"10.1016\/j.medcli.2025.107107_bib0435","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1097\/MBP.0b013e328346d603","article-title":"Age and the difference between awake ambulatory blood pressure and office blood pressure: A meta-analysis","volume":"16","author":"Ishikawa","year":"2011","journal-title":"Blood Press Monit"},{"key":"10.1016\/j.medcli.2025.107107_bib0440","doi-asserted-by":"crossref","first-page":"3765","DOI":"10.1093\/eurheartj\/ehac347","article-title":"Association between hypotension during 24h ambulatory blood pressure monitoring and reflex syncope: The SynABPM 1 study","volume":"43","author":"Rivasi","year":"2022","journal-title":"Eur Heart J"},{"key":"10.1016\/j.medcli.2025.107107_bib0445","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1001\/archinte.166.5.515","article-title":"Carotid Sinus Hypersensitivity in Asymptomatic Older Persons: Implications for Diagnosis of Syncope and Falls","volume":"166","author":"Kerr","year":"2006","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.medcli.2025.107107_bib0450","doi-asserted-by":"crossref","first-page":"euae266","DOI":"10.1093\/europace\/euae266","article-title":"Carotid sinus massage in clinical practice: the Six-Step-Method","volume":"26","author":"De Lange","year":"2024","journal-title":"Europace"},{"key":"10.1016\/j.medcli.2025.107107_bib0455","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.ijcard.2012.09.023","article-title":"Head-up tilt testing for diagnosing vasovagal syncope: A meta-analysis","volume":"168","author":"Forleo","year":"2013","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.medcli.2025.107107_bib0460","doi-asserted-by":"crossref","first-page":"2473","DOI":"10.1093\/eurheartj\/ehad322","article-title":"Short-duration head-up tilt test potentiated with sublingual nitroglycerin in suspected vasovagal syncope: The fast Italian protocol","volume":"44","author":"Russo","year":"2023","journal-title":"Eur Heart J"},{"key":"10.1016\/j.medcli.2025.107107_bib0465","doi-asserted-by":"crossref","first-page":"2473","DOI":"10.1093\/eurheartj\/ehad322","article-title":"Short-duration head-up tilt test potentiated with sublingual nitroglycerin in suspected vasovagal syncope: The fast Italian protocol","volume":"44","author":"Russo","year":"2023","journal-title":"Eur Heart J"},{"key":"10.1016\/j.medcli.2025.107107_bib0470","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1016\/j.recesp.2018.04.013","article-title":"Diagnostic Yield and Economic Assessment of a Diagnostic Protocol With Systematic Use of an External Loop Recorder for Patients With Palpitations [Article in English, Spanish]","volume":"72","author":"Francisco-Pascual","year":"2019","journal-title":"Rev Esp Cardiol (Engl Ed)"},{"key":"10.1016\/j.medcli.2025.107107_bib0475","doi-asserted-by":"crossref","first-page":"1265","DOI":"10.1093\/europace\/euv311","article-title":"External prolonged electrocardiogram monitoring in unexplained syncope and palpitations: Results of the SYNARR-Flash study","volume":"18","author":"Locati","year":"2016","journal-title":"Europace"},{"key":"10.1016\/j.medcli.2025.107107_bib0480","doi-asserted-by":"crossref","first-page":"608","DOI":"10.4330\/wjc.v13.i11.608","article-title":"Cardiac monitoring for patients with palpitations","volume":"13","author":"Francisco-Pascual","year":"2021","journal-title":"World J Cardiol"},{"key":"10.1016\/j.medcli.2025.107107_bib0485","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/j.ijcard.2020.05.078","article-title":"High incidence of subclinical atrial fibrillation in patients with syncope monitored with implantable cardiac monitor","volume":"316","author":"Francisco-Pascual","year":"2020","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.medcli.2025.107107_bib0490","doi-asserted-by":"crossref","first-page":"914","DOI":"10.1093\/europace\/eut337","article-title":"Role of extended external loop recorders for the diagnosis of unexplained syncope, pre-syncope, and sustained palpitations","volume":"16","author":"Locati","year":"2014","journal-title":"Europace"},{"key":"10.1016\/j.medcli.2025.107107_bib0495","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1093\/eurheartj\/ehi602","article-title":"The clinical impact of implantable loop recorders in patients with syncope","volume":"27","author":"Farwell","year":"2006","journal-title":"Eur Heart J"},{"key":"10.1016\/j.medcli.2025.107107_bib0500","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1161\/01.CIR.104.1.46","article-title":"Randomized assessment of syncope trial: Conventional diagnostic testing versus a prolonged monitoring strategy","volume":"104","author":"Krahn","year":"2001","journal-title":"Circulation"},{"key":"10.1016\/j.medcli.2025.107107_bib0505","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/j.acvd.2012.12.002","article-title":"Clinical impact of the implantable loop recorder in patients with isolated syncope, bundle branch block and negative workup: A randomized multicentre prospective study","volume":"106","author":"Da Costa","year":"2013","journal-title":"Arch Cardiovasc Dis"},{"key":"10.1016\/j.medcli.2025.107107_bib0510","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1016\/j.acvd.2014.05.009","article-title":"Early use of an implantable loop recorder in syncope evaluation: A randomized study in the context of the French healthcare system (FRESH study)","volume":"107","author":"Podoleanu","year":"2014","journal-title":"Arch Cardiovasc Dis"},{"key":"10.1016\/j.medcli.2025.107107_bib0515","doi-asserted-by":"crossref","first-page":"912","DOI":"10.1093\/europace\/euv228","article-title":"The benefit of a remotely monitored implantable loop recorder as a first line investigation in unexplained syncope: The EaSyAS II trial","volume":"18","author":"Sulke","year":"2016","journal-title":"Europace"},{"key":"10.1016\/j.medcli.2025.107107_bib0520","doi-asserted-by":"crossref","first-page":"1479","DOI":"10.1093\/europace\/euab054","article-title":"A randomized study of yoga therapy for the prevention of recurrent reflex vasovagal syncope","volume":"23","author":"Shenthar","year":"2021","journal-title":"Europace"},{"key":"10.1016\/j.medcli.2025.107107_bib0525","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1136\/heartjnl-2016-309865","article-title":"Stop vasodepressor drugs in reflex syncope: A randomised controlled trial","volume":"103","author":"Solari","year":"2017","journal-title":"Heart"},{"key":"10.1016\/j.medcli.2025.107107_bib0530","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1093\/ageing\/afv199","article-title":"Effect of discontinuation of antihypertensive medication on orthostatic hypotension in older persons with mild cognitive impairment: the DANTE Study Leiden","volume":"45","author":"Moonen","year":"2016","journal-title":"Age Ageing"},{"key":"10.1016\/j.medcli.2025.107107_bib0535","doi-asserted-by":"crossref","DOI":"10.1093\/europace\/euae026","article-title":"Interventions aimed to increase average 24-h systolic blood pressure reduce blood pressure drops in patients with reflex syncope and orthostatic intolerance","volume":"26","author":"Groppelli","year":"2024","journal-title":"Europace"},{"key":"10.1016\/j.medcli.2025.107107_bib0540","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.ejim.2024.05.014","article-title":"Targets for deprescribing in patients with hypertension and reflex syncope","volume":"128","author":"Groppelli","year":"2024","journal-title":"Eur J Intern Med"},{"key":"10.1016\/j.medcli.2025.107107_bib0545","doi-asserted-by":"crossref","first-page":"1425","DOI":"10.1016\/j.jacc.2006.06.052","article-title":"Lower limb and abdominal compression bandages prevent progressive orthostatic hypotension in elderly persons: A randomized single-blind controlled study","volume":"48","author":"Podoleanu","year":"2006","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.medcli.2025.107107_bib0550","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jacc.2016.04.030","article-title":"Fludrocortisone for the Prevention of Vasovagal Syncope: A Randomized Placebo-Controlled Trial","volume":"68","author":"Sheldon","year":"2016","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.medcli.2025.107107_bib0555","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1007\/s10286-024-01096-3","article-title":"Haemodynamic effects of fludrocortisone and midodrine in patients with symptoms due to hypotension","volume":"35","author":"De Lange","year":"2025","journal-title":"Clin Auton Res"},{"key":"10.1016\/j.medcli.2025.107107_bib0560","doi-asserted-by":"crossref","first-page":"1349","DOI":"10.7326\/M20-5415","article-title":"Midodrine for the Prevention of Vasovagal Syncope: A Randomized Clinical Trial","volume":"174","author":"Sheldon","year":"2021","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.medcli.2025.107107_bib0565","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1016\/j.hrthm.2015.12.016","article-title":"Efficacy of theophylline in patients affected by low adenosine syncope","volume":"13","author":"Brignole","year":"2016","journal-title":"Heart Rhythm"},{"key":"10.1016\/j.medcli.2025.107107_bib0570","doi-asserted-by":"crossref","first-page":"1164","DOI":"10.1093\/europace\/euab300","article-title":"Theophylline in patients with syncope without prodrome, normal heart, and normal electrocardiogram: A propensity-score matched study verified by implantable cardiac monitor","volume":"24","author":"Brignole","year":"2022","journal-title":"Europace"},{"key":"10.1016\/j.medcli.2025.107107_bib0575","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.jacep.2022.08.011","article-title":"Cardioneuroablation for Reflex Syncope: Efficacy and Effects on Autonomic Cardiac Regulation-A Prospective Randomized Trial","volume":"9","author":"Piotrowski","year":"2023","journal-title":"JACC Clin Electrophysiol"},{"key":"10.1016\/j.medcli.2025.107107_bib0580","doi-asserted-by":"crossref","first-page":"2711","DOI":"10.1016\/j.jacep.2024.07.027","article-title":"Predictors of Clinical Success of Cardioneuroablation in Patients With Syncope: Results of a Multicenter Study","volume":"10","author":"Barrio-Lopez","year":"2024","journal-title":"JACC Clin Electrophysiol"},{"key":"10.1016\/j.medcli.2025.107107_bib0585","doi-asserted-by":"crossref","first-page":"1733","DOI":"10.1093\/europace\/euz250","article-title":"A proof of principle study of atomoxetine for the prevention of vasovagal syncope: The Prevention of Syncope Trial VI","volume":"21","author":"Sheldon","year":"2019","journal-title":"Europace"},{"key":"10.1016\/j.medcli.2025.107107_bib0590","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/j.ccl.2012.10.001","article-title":"Pacemaker therapy in syncope","volume":"31","author":"Moya","year":"2013","journal-title":"Cardiol Clin"},{"key":"10.1016\/j.medcli.2025.107107_bib0595","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1093\/europace\/euz294","article-title":"Impact of dual-chamber pacing with closed loop stimulation on quality of life in patients with recurrent reflex vasovagal syncope: Results of the SPAIN study","volume":"22","author":"Bar\u00f3n-Esquivias","year":"2020","journal-title":"Europace"},{"key":"10.1016\/j.medcli.2025.107107_bib0600","doi-asserted-by":"crossref","first-page":"1427","DOI":"10.1093\/europace\/euv343","article-title":"Standardized algorithm for cardiac pacing in older patients affected by severe unpredictable reflex syncope: 3-year insights from the Syncope Unit Project 2 (SUP 2) study","volume":"18","author":"Brignole","year":"2016","journal-title":"Europace"},{"key":"10.1016\/j.medcli.2025.107107_bib0605","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1093\/eurheartj\/ehaa936","article-title":"Cardiac pacing in severe recurrent reflex syncope and tilt-induced asystole","volume":"42","author":"Brignole","year":"2021","journal-title":"Eur Heart J"},{"key":"10.1016\/j.medcli.2025.107107_bib0610","doi-asserted-by":"crossref","first-page":"1164","DOI":"10.1161\/CIRCULATIONAHA.105.535161","article-title":"Prevention of Syncope Trial (POST): A randomized, placebo-controlled study of metoprolol in the prevention of vasovagal syncope","volume":"113","author":"Sheldon","year":"2006","journal-title":"Circulation"},{"key":"10.1016\/j.medcli.2025.107107_bib0615","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1093\/europace\/euw153","article-title":"Fluoxetine vs. placebo for the treatment of recurrent vasovagal syncope with anxiety sensitivity","volume":"19","author":"Flevari","year":"2017","journal-title":"Europace"},{"key":"10.1016\/j.medcli.2025.107107_bib0620","doi-asserted-by":"crossref","first-page":"2566","DOI":"10.1161\/CIRCULATIONAHA.111.082313","article-title":"Pacemaker therapy in patients with neurally mediated syncope and documented asystole: Third International Study on Syncope of Uncertain Etiology (ISSUE-3): A randomized trial","volume":"125","author":"Brignole","year":"2012","journal-title":"Circulation"}],"container-title":["Medicina Cl\u00ednica"],"original-title":[],"language":"es","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0025775325003355?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0025775325003355?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,12,30]],"date-time":"2025-12-30T16:51:42Z","timestamp":1767113502000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0025775325003355"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9]]},"references-count":61,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2025,9]]}},"alternative-id":["S0025775325003355"],"URL":"https:\/\/doi.org\/10.1016\/j.medcli.2025.107107","relation":{},"ISSN":["0025-7753"],"issn-type":[{"value":"0025-7753","type":"print"}],"subject":[],"published":{"date-parts":[[2025,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"S\u00edncope auton\u00f3mico","name":"articletitle","label":"Article Title"},{"value":"Medicina Cl\u00ednica","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.medcli.2025.107107","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Espa\u00f1a, S.L.U. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"107107"}}