{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T17:16:23Z","timestamp":1778001383742,"version":"3.51.4"},"reference-count":30,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.es","elsevier.es","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Medicina Cl\u00ednica"],"published-print":{"date-parts":[[2026,5]]},"DOI":"10.1016\/j.medcli.2026.107365","type":"journal-article","created":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T12:50:56Z","timestamp":1773233456000},"page":"107365","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Alteraciones respiratorias en pacientes con esclerosis lateral amiotr\u00f3fica"],"prefix":"10.1016","volume":"166","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2654-5482","authenticated-orcid":false,"given":"Vanessa","family":"Riveiro","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luc\u00eda","family":"Ferreiro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Romina","family":"Abelleira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nuria","family":"Rodr\u00edguez-N\u00fa\u00f1ez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda E.","family":"Toubes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jorge","family":"Ricoy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tania","family":"Garc\u00eda-Sobrino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luis","family":"Vald\u00e9s","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlos","family":"Zamarr\u00f3n","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.medcli.2026.107365_bib0155","doi-asserted-by":"crossref","DOI":"10.1038\/ncomms12408","article-title":"Projected increase in amyotrophic lateral sclerosis from 2015 to 2040","volume":"7","author":"Arthur","year":"2016","journal-title":"Nat Commun."},{"key":"10.1016\/j.medcli.2026.107365_bib0160","series-title":"Amyotrophic Lateral Sclerosis","article-title":"Time to diagnosis and factors affecting diagnostic delay in amyotrophic lateral sclerosis","author":"Richards","year":"2021"},{"key":"10.1016\/j.medcli.2026.107365_bib0165","doi-asserted-by":"crossref","DOI":"10.1016\/j.clineuro.2019.105456","article-title":"The prognostic value of spirometric tests in amyotrophic lateral sclerosis patients","volume":"184","author":"Pirola","year":"2019","journal-title":"Clin Neurol Neurosurg."},{"key":"10.1016\/j.medcli.2026.107365_bib0170","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1016\/j.arbres.2012.12.003","article-title":"Normativa sobre el manejo de las complicaciones respiratorias de los pacientes con enfermedad neuromuscular","volume":"49","author":"Farrero","year":"2013","journal-title":"Arch Bronconeumol."},{"key":"10.1016\/j.medcli.2026.107365_bib0175","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1007\/s11910-011-0248-1","article-title":"Sleep-disordered breathing in neurodegenerative diseases","volume":"12","author":"Gaig","year":"2012","journal-title":"Curr Neurol Neurosci Rep."},{"key":"10.1016\/j.medcli.2026.107365_bib0180","doi-asserted-by":"crossref","DOI":"10.1136\/bmj-2023-075037","article-title":"Advances in molecular pathology, diagnosis, and treatment of amyotrophic lateral sclerosis","volume":"383","author":"Ilieva","year":"2023","journal-title":"BMJ."},{"key":"10.1016\/j.medcli.2026.107365_bib0185","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1080\/146608200300079536","article-title":"El Escorial revisited: revised criteria for the diagnosis of amyotrophic lateral sclerosis","volume":"1","author":"Brooks","year":"2000","journal-title":"Amyotroph Lateral Scler Other Motor Neuron Disord."},{"key":"10.1016\/j.medcli.2026.107365_bib0190","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1002\/mus.27392","article-title":"Gold Coast diagnostic criteria: implications for ALS diagnosis and clinical trial enrollment","volume":"64","author":"Vucic","year":"2021","journal-title":"Muscle Nerve."},{"key":"10.1016\/j.medcli.2026.107365_bib0195","series-title":"Proceso asistencial integrado de esclerosis lateral amiotr\u00f3fica","author":"Alonso Fachado","year":"2018"},{"key":"10.1016\/j.medcli.2026.107365_bib0200","doi-asserted-by":"crossref","first-page":"475","DOI":"10.3109\/17482968.2010.489115","article-title":"Spanish adaptation of the revised Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS-R)","volume":"11","author":"Campos","year":"2010","journal-title":"Amyotroph Lateral Scler."},{"key":"10.1016\/j.medcli.2026.107365_bib0205","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/j.arbres.2021.03.017","article-title":"International Consensus Document on Obstructive Sleep Apnea","volume":"58","author":"Mediano","year":"2022","journal-title":"Arch Bronconeumol."},{"key":"10.1016\/j.medcli.2026.107365_bib0210","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1056\/NEJMra1603471","article-title":"Amyotrophic lateral sclerosis","volume":"377","author":"Brown","year":"2017","journal-title":"N Engl J Med."},{"key":"10.1016\/j.medcli.2026.107365_bib0215","doi-asserted-by":"crossref","first-page":"5397","DOI":"10.1007\/s10072-022-06157-x","article-title":"Cognition and motor phenotypes in ALS: a retrospective study","volume":"43","author":"Aiello","year":"2022","journal-title":"Neurol Sci."},{"key":"10.1016\/j.medcli.2026.107365_bib0220","doi-asserted-by":"crossref","DOI":"10.1016\/j.aprim.2021.102158","article-title":"La esclerosis lateral amiotr\u00f3fica (ELA) desde la Atenci\u00f3n Primaria. Epidemiolog\u00eda y caracter\u00edsticas cl\u00ednico-asistenciales","volume":"53","author":"Castro-Rodr\u00edguez","year":"2021","journal-title":"Aten Primaria."},{"key":"10.1016\/j.medcli.2026.107365_bib0225","doi-asserted-by":"crossref","first-page":"278","DOI":"10.3109\/21678421.2012.749915","article-title":"Amyotrophic lateral sclerosis in Catalonia: a population based study","volume":"14","author":"Pradas","year":"2013","journal-title":"Amyotroph Lateral Scler Frontotemporal Degener."},{"key":"10.1016\/j.medcli.2026.107365_bib0230","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1002\/ana.21653","article-title":"Smoking and risk for amyotrophic lateral sclerosis: analysis of the EPIC cohort","volume":"65","author":"Gallo","year":"2009","journal-title":"Ann Neurol."},{"key":"10.1016\/j.medcli.2026.107365_bib0235","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1038\/s41576-023-00592-y","article-title":"Amyotrophic lateral sclerosis: translating genetic discoveries into therapies","volume":"24","author":"Ak\u00e7imen","year":"2023","journal-title":"Nat Rev Genet."},{"key":"10.1016\/j.medcli.2026.107365_bib0240","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.jsmc.2014.05.014","article-title":"Pathophysiology of hypoventilation during sleep","volume":"9","author":"Berger","year":"2014","journal-title":"Sleep Med Clin."},{"key":"10.1016\/j.medcli.2026.107365_bib0245","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1136\/jnnp-2017-316515","article-title":"Prevalence of sleep apnoea and capnographic detection of nocturnal hypoventilation in amyotrophic lateral sclerosis","volume":"89","author":"Boentert","year":"2018","journal-title":"J Neurol Neurosurg Psychiatry."},{"key":"10.1016\/j.medcli.2026.107365_bib0250","first-page":"160","article-title":"Sleep-related breathing disorders in amyotrophic lateral sclerosis","volume":"59","author":"Santos","year":"2003","journal-title":"Monaldi Arch Chest Dis."},{"key":"10.1016\/j.medcli.2026.107365_bib0255","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1159\/000447560","article-title":"The prognostic role of obstructive sleep apnea at the onset of amyotrophic lateral sclerosis","volume":"17","author":"Quaranta","year":"2017","journal-title":"Neurodegener Dis."},{"key":"10.1016\/j.medcli.2026.107365_bib0260","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/S0022-510X(99)00044-1","article-title":"Sleep-disordered breathing at an early stage of amyotrophic lateral sclerosis","volume":"164","author":"Kimura","year":"1999","journal-title":"J Neurol Sci."},{"key":"10.1016\/j.medcli.2026.107365_bib0265","first-page":"1284","article-title":"Sleep disturbances in amyotrophic lateral sclerosis and prognostic impact \u2014 a retrospective study","volume":"14","author":"Silva","year":"2024","journal-title":"Life (Basel)."},{"key":"10.1016\/j.medcli.2026.107365_bib0270","doi-asserted-by":"crossref","first-page":"4321","DOI":"10.1007\/s00415-021-10563-0","article-title":"Respiratory parameters on diagnostic sleep studies predict survival in patients with amyotrophic lateral sclerosis","volume":"268","author":"Engel","year":"2021","journal-title":"J Neurol."},{"key":"10.1016\/j.medcli.2026.107365_bib0275","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.sleep.2016.05.016","article-title":"Isolated rapid eye movement sleep without atonia in amyotrophic lateral sclerosis","volume":"26","author":"Puligheddu","year":"2016","journal-title":"Sleep Med."},{"key":"10.1016\/j.medcli.2026.107365_bib0280","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1111\/ane.12593","article-title":"REM sleep behavior disorder and periodic leg movements during sleep in ALS","volume":"135","author":"Lo Coco","year":"2017","journal-title":"Acta Neurol Scand."},{"key":"10.1016\/j.medcli.2026.107365_bib0285","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1136\/jnnp-2015-312606","article-title":"Reduced survival in patients with ALS with upper airway obstructive events on non-invasive ventilation","volume":"87","author":"Georges","year":"2016","journal-title":"J Neurol Neurosurg Psychiatry."},{"key":"10.1016\/j.medcli.2026.107365_bib0290","doi-asserted-by":"crossref","first-page":"1022","DOI":"10.1136\/jnnp-2015-312185","article-title":"Assessment of pulmonary function in amyotrophic lateral sclerosis: when can polygraphy help evaluate the need for non-invasive ventilation?","volume":"87","author":"Prell","year":"2016","journal-title":"J Neurol Neurosurg Psychiatry."},{"key":"10.1016\/j.medcli.2026.107365_bib0295","first-page":"40","article-title":"Prognostic value of initial assessment of residual hypoventilation using nocturnal capnography in mechanically ventilated neuromuscular patients: a 5-year follow-up study","volume":"3","author":"Ogna","year":"2016","journal-title":"Front Med (Lausanne)."},{"key":"10.1016\/j.medcli.2026.107365_bib0300","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1136\/jnnp.2005.072660","article-title":"Forced vital capacity (FVC) as an indicator of survival and disease progression in an ALS clinic population","volume":"77","author":"Czaplinski","year":"2006","journal-title":"J Neurol Neurosurg Psychiatry."}],"container-title":["Medicina Cl\u00ednica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0025775326000151?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0025775326000151?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T16:42:24Z","timestamp":1777999344000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0025775326000151"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5]]},"references-count":30,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,5]]}},"alternative-id":["S0025775326000151"],"URL":"https:\/\/doi.org\/10.1016\/j.medcli.2026.107365","relation":{},"ISSN":["0025-7753"],"issn-type":[{"value":"0025-7753","type":"print"}],"subject":[],"published":{"date-parts":[[2026,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Alteraciones respiratorias en pacientes con esclerosis lateral amiotr\u00f3fica","name":"articletitle","label":"Article Title"},{"value":"Medicina Cl\u00ednica","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.medcli.2026.107365","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Espa\u00f1a, S.L.U. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"107365"}}