{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T17:14:51Z","timestamp":1760548491476},"reference-count":31,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2007,9,1]],"date-time":"2007-09-01T00:00:00Z","timestamp":1188604800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medical Dosimetry"],"published-print":{"date-parts":[[2007,9]]},"DOI":"10.1016\/j.meddos.2007.01.002","type":"journal-article","created":{"date-parts":[[2007,8,16]],"date-time":"2007-08-16T16:53:24Z","timestamp":1187283204000},"page":"188-195","source":"Crossref","is-referenced-by-count":21,"title":["Intensity Modulated Radiotherapy Improves Target Coverage and Parotid Gland Sparing When Delivering Total Mucosal Irradiation in Patients With Squamous Cell Carcinoma of Head and Neck of Unknown Primary Site"],"prefix":"10.1016","volume":"32","author":[{"given":"Shreerang","family":"Bhide","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Catherine","family":"Clark","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kevin","family":"Harrington","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher M.","family":"Nutting","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.meddos.2007.01.002_bib1","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1016\/S0360-3016(01)01462-6","article-title":"Cervical lymph node metastases from occult squamous cell carcinoma: Cut down a tree to get an apple?","volume":"50","author":"Nieder","year":"2001","journal-title":"Int. J. Radiat. Oncol. Biol. Phys."},{"key":"10.1016\/j.meddos.2007.01.002_bib2","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/S0167-8140(00)00172-9","article-title":"Cervical lymph node metastases from unknown primary tumours","volume":"55","author":"Grau","year":"2000","journal-title":"Radiother. Oncol."},{"key":"10.1016\/j.meddos.2007.01.002_bib3","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1002\/1097-0347(200102)23:2<113::AID-HED1006>3.0.CO;2-W","article-title":"Health-related quality of life three years after diagnosis of head and neck cancer\u2014a longitudinal study","volume":"23","author":"Hammerlid","year":"2001","journal-title":"Head Neck"},{"key":"10.1016\/j.meddos.2007.01.002_bib4","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1054\/bjoc.2000.1576","article-title":"Health-related quality of life in long-term head and neck cancer survivors: A comparison with general population norms","volume":"84","author":"Hammerlid","year":"2001","journal-title":"Br. J. Cancer."},{"key":"10.1016\/j.meddos.2007.01.002_bib5","doi-asserted-by":"crossref","first-page":"1012","DOI":"10.1002\/cncr.10342","article-title":"Quality of life of nasopharyngeal carcinoma patients","volume":"94","author":"Talmi","year":"2002","journal-title":"Cancer"},{"key":"10.1016\/j.meddos.2007.01.002_bib6","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1016\/S1053-4296(03)00033-X","article-title":"How should we measure and report radiotherapy-induced xerostomia?","volume":"13","author":"Eisbruch","year":"2003","journal-title":"Semin. Radiat. Oncol."},{"key":"10.1016\/j.meddos.2007.01.002_bib7","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1016\/S0360-3016(96)00264-7","article-title":"Parotid gland sparing in patients undergoing bilateral head and neck irradiation: Techniques and early results","volume":"36","author":"Eisbruch","year":"1996","journal-title":"Int. J. Radiat. Oncol. Biol. Phys."},{"key":"10.1016\/j.meddos.2007.01.002_bib8","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1016\/S0360-3016(98)00082-0","article-title":"Comprehensive irradiation of head and neck cancer using conformal multisegmental fields: Assessment of target coverage and noninvolved tissue sparing","volume":"41","author":"Eisbruch","year":"1998","journal-title":"Int. J. Radiat. Oncol. Biol. Phys."},{"key":"10.1016\/j.meddos.2007.01.002_bib9","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1016\/S0360-3016(99)00247-3","article-title":"Dose, volume, and function relationships in parotid salivary glands following conformal and intensity-modulated irradiation of head and neck cancer","volume":"45","author":"Eisbruch","year":"1999","journal-title":"Int. J. Radiat. Oncol. Biol. Phys."},{"key":"10.1016\/j.meddos.2007.01.002_bib10","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/S1368-8375(98)00104-3","article-title":"Two-year longitudinal study of parotid salivary flow rates in head and neck cancer patients receiving unilateral neck parotid-sparing radiotherapy treatment","volume":"35","author":"Henson","year":"1999","journal-title":"Oral Oncol."},{"key":"10.1016\/j.meddos.2007.01.002_bib11","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/S0360-3016(03)00361-4","article-title":"Quality of life after parotid-sparing IMRT for head-and-neck cancer: A prospective longitudinal study","volume":"57","author":"Lin","year":"2003","journal-title":"Int. J. Radiat. Oncol. Biol. Phys."},{"key":"10.1016\/j.meddos.2007.01.002_bib12","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1016\/S0360-3016(03)01571-2","article-title":"Preservation of oral health-related quality of life and salivary flow rates after inverse-planned intensity-modulated radiotherapy (IMRT) for head-and-neck cancer","volume":"58","author":"Parliament","year":"2004","journal-title":"Int. J. Radiat. Oncol. Biol. Phys."},{"key":"10.1016\/j.meddos.2007.01.002_bib13","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1016\/S0360-3016(00)00702-1","article-title":"Three-dimensional intensity-modulated radiotherapy in the treatment of nasopharyngeal carcinoma: The University of California-San Francisco experience","volume":"48","author":"Sultanem","year":"2000","journal-title":"Int. J. Radiat. Oncol. Biol. Phys."},{"key":"10.1016\/j.meddos.2007.01.002_bib14","series-title":"ICRU Report 50","article-title":"Prescribing, Recording and Reporting Photon Beam Therapy","year":"1993"},{"key":"10.1016\/j.meddos.2007.01.002_bib15","series-title":"Prescribing, Recording and Reporting Photon Beam Therapy (Supplement to ICRU Report 50)","year":"1999"},{"key":"10.1016\/j.meddos.2007.01.002_bib16","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/j.radonc.2005.10.011","article-title":"The impact of introducing intensity modulated radiotherapy into routine clinical practice","volume":"77","author":"Miles","year":"2005","journal-title":"Radiother. Oncol."},{"key":"10.1016\/j.meddos.2007.01.002_bib17","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/S0167-8140(00)00202-4","article-title":"Selection and delineation of lymph node target volumes in head and neck conformal radiotherapy","volume":"56","author":"Gregoire","year":"2000","journal-title":"Radiother. Oncol."},{"key":"10.1016\/j.meddos.2007.01.002_bib18","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.radonc.2006.03.009","article-title":"Proposal for the delineation of the nodal CTV in the node-positive and the post-operative neck","volume":"79","author":"Gregoire","year":"2006","journal-title":"Radiother. Oncol."},{"key":"10.1016\/j.meddos.2007.01.002_bib19","doi-asserted-by":"crossref","first-page":"1756","DOI":"10.1002\/1097-0142(19930901)72:5<1756::AID-CNCR2820720540>3.0.CO;2-5","article-title":"Squamous carcinoma presenting as an enlarged cervical lymph node","volume":"72","author":"Jones","year":"1993","journal-title":"Cancer"},{"key":"10.1016\/j.meddos.2007.01.002_bib20","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1002\/(SICI)1097-0347(199812)20:8<739::AID-HED13>3.0.CO;2-0","article-title":"Diagnostic evaluation of squamous cell carcinoma metastatic to cervical lymph nodes from an unknown head and neck primary site","volume":"20","author":"Mendenhall","year":"1998","journal-title":"Head Neck"},{"key":"10.1016\/j.meddos.2007.01.002_bib21","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1002\/(SICI)1097-0347(200005)22:3<275::AID-HED10>3.0.CO;2-N","article-title":"Neck node metastases from nasopharyngeal carcinoma: MR imaging of patterns of disease","volume":"22","author":"King","year":"2000","journal-title":"Head Neck"},{"key":"10.1016\/j.meddos.2007.01.002_bib22","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.radonc.2005.06.039","article-title":"Assessment of a customised immobilisation system for head and neck IMRT using electronic portal imaging","volume":"77","author":"Humphreys","year":"2005","journal-title":"Radiother. Oncol."},{"key":"10.1016\/j.meddos.2007.01.002_bib23","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1120\/1.1499095","article-title":"IMRT clinical implementation: Prostate and pelvic node irradiation by Helios using a 120-leaf MLC","volume":"3","author":"Clark","year":"2002","journal-title":"J. Appl. Clin. Med. Phys."},{"key":"10.1016\/j.meddos.2007.01.002_bib24","doi-asserted-by":"crossref","first-page":"2917","DOI":"10.1088\/0031-9155\/44\/12\/305","article-title":"Calculation of a pencil beam kernel from measured photon beam data","volume":"44","author":"Storchi","year":"1999","journal-title":"Phys. Med. Biol."},{"key":"10.1016\/j.meddos.2007.01.002_bib25","doi-asserted-by":"crossref","first-page":"147","DOI":"10.3109\/02841868109130436","article-title":"Electron beam dose planning using discrete Gaussian beams","volume":"20","author":"Brahme","year":"1981","journal-title":"Acta Radiol. Oncol."},{"key":"10.1016\/j.meddos.2007.01.002_bib26","doi-asserted-by":"crossref","first-page":"75","DOI":"10.3109\/02841868509134369","article-title":"Electron beam dose planning using Gaussian beams","volume":"24","author":"Lax","year":"1985","journal-title":"Acta Radiol. Oncol."},{"key":"10.1016\/j.meddos.2007.01.002_bib27","first-page":"49","article-title":"Electron beam dose planning using Gaussian beams","volume":"364","author":"Lax","year":"1983","journal-title":"Acta Radiol. Suppl."},{"key":"10.1016\/j.meddos.2007.01.002_bib28","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1016\/S0360-3016(98)00206-5","article-title":"A comparison of three stereotactic radiotherapy techniques: ARCS vs. noncoplanar fixed fields vs. intensity modulation","volume":"42","author":"Cardinale","year":"1998","journal-title":"Int. J. Radiat. Oncol. Biol. Phys."},{"key":"10.1016\/j.meddos.2007.01.002_bib29","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1016\/S0360-3016(99)00213-8","article-title":"Comparison of intensity-modulated tomotherapy with stereotactically guided conformal radiotherapy for brain tumors","volume":"45","author":"Khoo","year":"1999","journal-title":"Int. J. Radiat. Oncol. Biol. Phys."},{"key":"10.1016\/j.meddos.2007.01.002_bib30","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1259\/bjr.73.869.10884741","article-title":"Intensity modulated radiation therapy: A clinical review","volume":"73","author":"Nutting","year":"2000","journal-title":"Br. J. Radiol."},{"key":"10.1016\/j.meddos.2007.01.002_bib31","doi-asserted-by":"crossref","first-page":"938","DOI":"10.1016\/S0360-3016(01)01717-5","article-title":"Quantitative dose-volume response analysis of changes in parotid gland function after radiotherapy in the head-and-neck region","volume":"51","author":"Roesink","year":"2001","journal-title":"Int. J. Radiat. Oncol. Biol. Phys."}],"container-title":["Medical Dosimetry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0958394707000027?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0958394707000027?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,1,5]],"date-time":"2019-01-05T04:20:26Z","timestamp":1546662026000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0958394707000027"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,9]]},"references-count":31,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2007,9]]}},"alternative-id":["S0958394707000027"],"URL":"https:\/\/doi.org\/10.1016\/j.meddos.2007.01.002","relation":{},"ISSN":["0958-3947"],"issn-type":[{"value":"0958-3947","type":"print"}],"subject":[],"published":{"date-parts":[[2007,9]]}}}