{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T17:26:26Z","timestamp":1760549186888},"reference-count":18,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2012,9,1]],"date-time":"2012-09-01T00:00:00Z","timestamp":1346457600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medical Dosimetry"],"published-print":{"date-parts":[[2012,9]]},"DOI":"10.1016\/j.meddos.2011.10.002","type":"journal-article","created":{"date-parts":[[2011,12,20]],"date-time":"2011-12-20T01:05:04Z","timestamp":1324343104000},"page":"276-279","source":"Crossref","is-referenced-by-count":4,"title":["Tumor histology and location predict deep nuclei toxicity: Implications for late effects from focal brain irradiation"],"prefix":"10.1016","volume":"37","author":[{"given":"Alexis","family":"Plaga","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lisa B.E.","family":"Shields","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David A.","family":"Sun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Todd W.","family":"Vitaz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aaron C.","family":"Spalding","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.meddos.2011.10.002_bib1","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1016\/j.ijrobp.2005.10.038","article-title":"Modeling radiation dosimetry to predict cognitive outcomes in pediatric patients with CNS embryonal tumors including medulloblastoma","volume":"65","author":"Merchant","year":"2006","journal-title":"Int. J. Radiat. Oncol. Biol. Phys."},{"key":"10.1016\/j.meddos.2011.10.002_bib2","doi-asserted-by":"crossref","first-page":"3691","DOI":"10.1200\/JCO.2008.21.2738","article-title":"Late effects of conformal radiation therapy for pediatric patients with low-grade glioma: Prospective evaluation of cognitive, endocrine, and hearing deficits","volume":"27","author":"Merchant","year":"2009","journal-title":"J. Clin. Oncol."},{"key":"10.1016\/j.meddos.2011.10.002_bib3","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1097\/01.nrl.0000144287.35993.96","article-title":"Long-term effects of radiation therapy on cognitive and endocrine function in children with leukemia and brain tumors","volume":"10","author":"Duffner","year":"2004","journal-title":"Neurologist"},{"key":"10.1016\/j.meddos.2011.10.002_bib4","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1002\/mpo.10055","article-title":"CNS late-effects after ALL therapy in childhood. part III: Neuropsychological performance in long-term survivors of childhood ALL: Impairments of concentration, attention, and memory","volume":"38","author":"Langer","year":"2002","journal-title":"Med. Pediatr. Oncol."},{"key":"10.1016\/j.meddos.2011.10.002_bib5","doi-asserted-by":"crossref","first-page":"S20","DOI":"10.1016\/j.ijrobp.2009.02.091","article-title":"Radiation dose-volume effects in the brain","volume":"76","author":"Lawrence","year":"2010","journal-title":"Int. J. Radiat. Oncol. Biol. Phys."},{"key":"10.1016\/j.meddos.2011.10.002_bib6","doi-asserted-by":"crossref","first-page":"198208","DOI":"10.1155\/2010\/198208","article-title":"Cognitive sparing during the administration of whole brain radiotherapy and prophylactic cranial irradiation: Current concepts and approaches","volume":"2010","author":"Marsh","year":"2010","journal-title":"J. Oncol."},{"key":"10.1016\/j.meddos.2011.10.002_bib7","doi-asserted-by":"crossref","first-page":"2330","DOI":"10.1210\/jc.2011-0306","article-title":"Pituitary dysfunction in adult patients after cranial radiotherapy: Systematic review and meta-analysis","volume":"96","author":"Appelman-Dijkstra","year":"2011","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.meddos.2011.10.002_bib8","doi-asserted-by":"crossref","first-page":"2267","DOI":"10.1200\/JCO.2002.09.126","article-title":"Prospective randomized trial of low-versus high-dose radiation therapy in adults with supratentorial low-grade glioma: Initial report of a North Central Cancer Treatment Group\/Radiation Therapy Oncology Group\/Eastern Cooperative Oncology Group study","volume":"20","author":"Shaw","year":"2002","journal-title":"J. Clin. Oncol."},{"key":"10.1016\/j.meddos.2011.10.002_bib9","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1016\/j.ijrobp.2007.05.038","article-title":"Whole brain radiotherapy with hippocampal avoidance and simultaneously integrated brain metastases boost: A planning study","volume":"69","author":"Guti\u00e9rrez","year":"2007","journal-title":"Int. J. Radiat. Oncol. Biol. Phys."},{"key":"10.1016\/j.meddos.2011.10.002_bib10","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1007\/BF03345714","article-title":"Late endocrine sequelae after radiotherapy of pediatric brain tumors are independent of tumor location","volume":"32","author":"Rohrer","year":"2009","journal-title":"J. Endocrinol. Invest."},{"key":"10.1016\/j.meddos.2011.10.002_bib11","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1530\/EJE-09-0690","article-title":"Adult final height after GH therapy for irradiation-induced GH deficiency in childhood survivors of brain tumors: The Belgian experience","volume":"162","author":"Beckers","year":"2010","journal-title":"Eur. J. Endocrinol."},{"key":"10.1016\/j.meddos.2011.10.002_bib12","first-page":"94","article-title":"Phase II trial of conformal radiation therapy for pediatric patients with craniopharyngioma and correlation of surgical factors and radiation dosimetry with change in cognitive function","volume":"104","author":"Merchant","year":"2006","journal-title":"J. Neurosurg."},{"key":"10.1016\/j.meddos.2011.10.002_bib13","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1016\/j.ijrobp.2008.05.040","article-title":"Relative contributions of radiation and cisplatin-based chemotherapy to sensorineural hearing loss in head-and-neck cancer patients","volume":"73","author":"Hitchcock","year":"2009","journal-title":"Int. J. Radiat. Oncol. Biol. Phys."},{"key":"10.1016\/j.meddos.2011.10.002_bib14","doi-asserted-by":"crossref","first-page":"S50","DOI":"10.1016\/j.ijrobp.2009.04.096","article-title":"Radiation therapy and hearing loss","volume":"76","author":"Bhandare","year":"2010","journal-title":"Int. J. Radiat. Oncol. Biol. Phys."},{"key":"10.1016\/j.meddos.2011.10.002_bib15","doi-asserted-by":"crossref","first-page":"1445","DOI":"10.1016\/j.ijrobp.2009.09.031","article-title":"Ototoxicity after intensity-modulated radiation therapy and cisplatin-based chemotherapy in children with medulloblastoma","volume":"78","author":"Paulino","year":"2010","journal-title":"Int. J. Radiat. Oncol. Biol. Phys."},{"key":"10.1016\/j.meddos.2011.10.002_bib16","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/j.ijrobp.2010.01.026","article-title":"Hypofractionated dose-painting intensity modulated radiation therapy with chemotherapy for nasopharyngeal carcinoma: A prospective trial","volume":"80","author":"Bakst","year":"2011","journal-title":"Int. J. Radiat. Oncol. Biol. Phys."},{"key":"10.1016\/j.meddos.2011.10.002_bib17","doi-asserted-by":"crossref","first-page":"S28","DOI":"10.1016\/j.ijrobp.2009.07.1753","article-title":"Radiation dose-volume effects of optic nerves and chiasm","volume":"76","author":"Mayo","year":"2010","journal-title":"Int. J. Radiat. Oncol. Biol. Phys."},{"key":"10.1016\/j.meddos.2011.10.002_bib18","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1111\/j.1365-2354.2008.01032.x","article-title":"The role of amifostine in the treatment of head and neck cancer with cisplatin-radiotherapy","volume":"18","author":"Marcu","year":"2009","journal-title":"Eur. J. Cancer Care [Engl]."}],"container-title":["Medical Dosimetry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0958394711002044?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0958394711002044?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,11,27]],"date-time":"2018-11-27T17:01:58Z","timestamp":1543338118000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0958394711002044"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,9]]},"references-count":18,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2012,9]]}},"alternative-id":["S0958394711002044"],"URL":"https:\/\/doi.org\/10.1016\/j.meddos.2011.10.002","relation":{},"ISSN":["0958-3947"],"issn-type":[{"value":"0958-3947","type":"print"}],"subject":[],"published":{"date-parts":[[2012,9]]}}}