{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T12:04:07Z","timestamp":1789387447760,"version":"build-2803163510"},"reference-count":27,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","meddos.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Medical Dosimetry"],"published-print":{"date-parts":[[2026,9]]},"DOI":"10.1016\/j.meddos.2026.08.008","type":"journal-article","created":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T11:12:08Z","timestamp":1789384328000},"update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Dosimetric and radiobiological evaluation of a spatially fractionated core-boost strategy in lung metastases within 5\u202fmm of the esophagus: Single-center plan-comparison study"],"prefix":"10.1016","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7084-4426","authenticated-orcid":false,"given":"\u0130brahim Halil","family":"Suyusal","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Onurhan","family":"\u00c7olak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmet Satuk","family":"Karag\u00f6z","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"10","key":"10.1016\/j.meddos.2026.08.008_bib0001","doi-asserted-by":"crossref","first-page":"1579","DOI":"10.1200\/JCO.2008.19.6386","article-title":"Multi-institutional phase I\/II trial of stereotactic body radiation therapy for lung metastases","volume":"27","author":"Rusthoven","year":"2009","journal-title":"J. Clin. Oncol."},{"issue":"10185","key":"10.1016\/j.meddos.2026.08.008_bib0002","doi-asserted-by":"crossref","first-page":"2051","DOI":"10.1016\/S0140-6736(18)32487-5","article-title":"Stereotactic ablative radiotherapy versus standard of care palliative treatment in patients with oligometastatic cancers (SABR-COMET): A randomised, phase 2, open-label trial","volume":"393","author":"Palma","year":"2019","journal-title":"Lancet"},{"issue":"1","key":"10.1016\/j.meddos.2026.08.008_bib0003","doi-asserted-by":"crossref","first-page":"e18","DOI":"10.1016\/S1470-2045(19)30718-1","article-title":"Characterisation and classification of oligometastatic disease: A European Society for Radiotherapy and Oncology and European Organisation for Research and Treatment of Cancer consensus recommendation","volume":"21","author":"Guckenberger","year":"2020","journal-title":"Lancet Oncol."},{"issue":"7","key":"10.1016\/j.meddos.2026.08.008_bib0004","doi-asserted-by":"crossref","first-page":"1200","DOI":"10.1016\/j.jtho.2021.03.019","article-title":"The HILUS-trial: A prospective nordic multicenter phase 2 study of ultracentral lung tumors treated with stereotactic body radiotherapy","volume":"16","author":"Lindberg","year":"2021","journal-title":"J. Thorac. Oncol."},{"issue":"15","key":"10.1016\/j.meddos.2026.08.008_bib0005","doi-asserted-by":"crossref","first-page":"1316","DOI":"10.1200\/JCO.18.00622","article-title":"Safety and efficacy of a five-fraction stereotactic body radiotherapy schedule for centrally located non-small-cell lung cancer: NRG Oncology\/RTOG 0813 trial","volume":"37","author":"Bezjak","year":"2019","journal-title":"J. Clin. Oncol."},{"issue":"8","key":"10.1016\/j.meddos.2026.08.008_bib0006","doi-asserted-by":"crossref","first-page":"4078","DOI":"10.1118\/1.3438081","article-title":"Stereotactic body radiation therapy: The report of AAPM Task Group 101","volume":"37","author":"Benedict","year":"2010","journal-title":"Med. Phys."},{"issue":"3 Suppl","key":"10.1016\/j.meddos.2026.08.008_bib0007","doi-asserted-by":"crossref","first-page":"S10","DOI":"10.1016\/j.ijrobp.2009.07.1754","article-title":"Use of normal tissue complication probability models in the clinic","volume":"76","author":"Marks","year":"2010","journal-title":"Int. J. Radiat. Oncol. Biol. Phys."},{"issue":"7 Suppl 3","key":"10.1016\/j.meddos.2026.08.008_bib0008","doi-asserted-by":"crossref","first-page":"S94","DOI":"10.1097\/JTO.0b013e318074de34","article-title":"Hypofractionated stereotactic radiotherapy (HypoFXSRT) for stage I non-small cell lung cancer: Updated results of 257 patients in a Japanese multi-institutional study","volume":"2","author":"Onishi","year":"2007","journal-title":"J. Thorac. Oncol."},{"issue":"3","key":"10.1016\/j.meddos.2026.08.008_bib0009","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1016\/S0360-3016(99)00170-4","article-title":"High-dose spatially-fractionated radiation (GRID): A new paradigm in the management of advanced cancers","volume":"45","author":"Mohiuddin","year":"1999","journal-title":"Int. J. Radiat. Oncol. Biol. Phys."},{"issue":"6","key":"10.1016\/j.meddos.2026.08.008_bib0010","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1667\/RADE-20-00066.1","article-title":"The technical and clinical implementation of LATTICE radiation therapy (LRT)","volume":"194","author":"Wu","year":"2020","journal-title":"Radiat. Res."},{"issue":"3","key":"10.1016\/j.meddos.2026.08.008_bib0011","article-title":"Spatially fractionated radiation therapy in sarcomas: A large single-institution experience","volume":"9","author":"Ahmed","year":"2023","journal-title":"Adv. Radiat. Oncol."},{"key":"10.1016\/j.meddos.2026.08.008_bib0012","article-title":"Salvage LATTICE radiotherapy for a growing tumour despite conventional radiochemotherapy treatment of lung cancer","volume":"39","author":"Kinj","year":"2022","journal-title":"Clin. Transl. Radiat. Oncol."},{"issue":"1","key":"10.1016\/j.meddos.2026.08.008_bib0013","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1118\/1.598063","article-title":"Reporting and analyzing dose distributions: A concept of equivalent uniform dose","volume":"24","author":"Niemierko","year":"1997","journal-title":"Med. Phys."},{"key":"10.1016\/j.meddos.2026.08.008_bib0014","first-page":"111","article-title":"Heterogeneous dose distributions inside the target volume in stereotactic body radiation therapy: A feasibility study","volume":"55","author":"Cilla","year":"2018","journal-title":"Phys. Med."},{"issue":"1","key":"10.1016\/j.meddos.2026.08.008_bib0015","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1186\/s13014-019-1227-y","article-title":"Novel stereotactic body radiation therapy (SBRT)-based partial tumor irradiation targeting hypoxic segment of bulky tumors (SBRT-PATHY): Improvement of the radiotherapy outcome","volume":"14","author":"Tubin","year":"2019","journal-title":"Radiat. Oncol."},{"key":"10.1016\/j.meddos.2026.08.008_bib0016","doi-asserted-by":"crossref","DOI":"10.3389\/fonc.2022.809279","article-title":"A novel radiotherapeutic approach to treat bulky metastases even from cutaneous squamous cell carcinoma: Its rationale and a look at the reliability of the linear-quadratic model to explain its radiobiological effects","volume":"12","author":"Ferini","year":"2022","journal-title":"Front. Oncol."},{"key":"10.1016\/j.meddos.2026.08.008_bib0017","doi-asserted-by":"crossref","DOI":"10.1016\/j.radonc.2023.109734","article-title":"ESTRO-ACROP guideline: Recommendations on implementation of breath-hold techniques in radiotherapy","volume":"185","author":"Aznar","year":"2023","journal-title":"RadiOther. Oncol."},{"issue":"3","key":"10.1016\/j.meddos.2026.08.008_bib0018","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1016\/j.ijrobp.2015.11.049","article-title":"Deep inspiration breath hold\u2014Based radiation therapy: A clinical review","volume":"94","author":"Boda-Heggemann","year":"2016","journal-title":"Int. J. Radiat. Oncol. Biol. Phys."},{"issue":"4","key":"10.1016\/j.meddos.2026.08.008_bib0019","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.1016\/j.ijrobp.2017.12.013","article-title":"American Association of Physicists in Medicine Task Group 263: Standardizing nomenclatures in radiation oncology","volume":"100","author":"Mayo","year":"2018","journal-title":"Int. J. Radiat. Oncol. Biol. Phys."},{"issue":"740","key":"10.1016\/j.meddos.2026.08.008_bib0020","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1259\/0007-1285-62-740-679","article-title":"The linear-quadratic formula and progress in fractionated radiotherapy","volume":"62","author":"Fowler","year":"1989","journal-title":"Br. J. Radiol."},{"issue":"4","key":"10.1016\/j.meddos.2026.08.008_bib0021","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.1016\/0360-3016(94)00475-Z","article-title":"Radiation dose-response of human tumors","volume":"32","author":"Okunieff","year":"1995","journal-title":"Int. J. Radiat. Oncol. Biol. Phys."},{"issue":"3","key":"10.1016\/j.meddos.2026.08.008_bib0022","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1016\/j.ijrobp.2007.10.059","article-title":"Universal survival curve and single fraction equivalent dose: Useful tools in understanding potency of ablative radiotherapy","volume":"70","author":"Park","year":"2008","journal-title":"Int. J. Radiat. Oncol. Biol. Phys."},{"issue":"6","key":"10.1016\/j.meddos.2026.08.008_bib0023","doi-asserted-by":"crossref","first-page":"1623","DOI":"10.1016\/0360-3016(89)90972-3","article-title":"Calculation of complication probability factors for non-uniform normal tissue irradiation: The effective volume method","volume":"16","author":"Kutcher","year":"1989","journal-title":"Int. J. Radiat. Oncol. Biol. Phys."},{"issue":"2","key":"10.1016\/j.meddos.2026.08.008_bib0024","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.radonc.2005.03.021","article-title":"Acute esophageal toxicity in non-small cell lung cancer patients after high dose conformal radiotherapy","volume":"75","author":"Belderbos","year":"2005","journal-title":"RadiOther. Oncol."},{"issue":"1","key":"10.1016\/j.meddos.2026.08.008_bib0025","first-page":"1","article-title":"ICRU report 83: Prescribing, recording, and reporting photon-beam intensity-modulated radiation therapy (IMRT)","volume":"10","author":"International Commission on Radiation Units and Measurements","year":"2010","journal-title":"J. ICRU"},{"key":"10.1016\/j.meddos.2026.08.008_bib0026","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1186\/s13014-016-0608-8","article-title":"Stereotactic body radiotherapy (SBRT) for high-risk central pulmonary metastases","volume":"11","author":"Lischalk","year":"2016","journal-title":"Radiat. Oncol."},{"issue":"4","key":"10.1016\/j.meddos.2026.08.008_bib0027","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1016\/j.prro.2011.10.004","article-title":"Stereotactic body radiation therapy and 3-dimensional conformal radiotherapy for stage I non-small cell lung cancer: A pooled analysis of biological equivalent dose and local control","volume":"2","author":"Mehta","year":"2012","journal-title":"Pract. Radiat. Oncol."}],"container-title":["Medical Dosimetry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S095839472600066X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S095839472600066X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T11:12:11Z","timestamp":1789384331000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S095839472600066X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9]]},"references-count":27,"alternative-id":["S095839472600066X"],"URL":"https:\/\/doi.org\/10.1016\/j.meddos.2026.08.008","relation":{},"ISSN":["0958-3947"],"issn-type":[{"value":"0958-3947","type":"print"}],"subject":[],"published":{"date-parts":[[2026,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Dosimetric and radiobiological evaluation of a spatially fractionated core-boost strategy in lung metastases within 5\u202fmm of the esophagus: Single-center plan-comparison study","name":"articletitle","label":"Article Title"},{"value":"Medical Dosimetry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.meddos.2026.08.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 American Association of Medical Dosimetrists. Published by Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}