{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,11]],"date-time":"2026-05-11T15:50:08Z","timestamp":1778514608680,"version":"3.51.4"},"reference-count":36,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2016,4,1]],"date-time":"2016-04-01T00:00:00Z","timestamp":1459468800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.es","elsevier.es","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Medicina Intensiva"],"published-print":{"date-parts":[[2016,4]]},"DOI":"10.1016\/j.medin.2016.02.001","type":"journal-article","created":{"date-parts":[[2016,3,22]],"date-time":"2016-03-22T10:42:38Z","timestamp":1458643358000},"page":"179-185","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":32,"title":["Infections in critically ill burn patients"],"prefix":"10.1016","volume":"40","author":[{"given":"F.","family":"Hidalgo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Mas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Rubio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Garcia-Hierro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.medin.2016.02.001_bib0185","doi-asserted-by":"crossref","first-page":"1148","DOI":"10.1016\/j.ajic.2013.09.002","article-title":"National Healthcare Safety Network (NHSN) report, data summary for 2012, device-associated module","volume":"41","author":"Dudeck","year":"2013","journal-title":"Am J Infect Control"},{"key":"10.1016\/j.medin.2016.02.001_bib0190","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1097\/BCR.0b013e3181599bc9","article-title":"American Burn Association consensus conference to define sepsis and infection in burns","volume":"28","author":"Greenhalgh","year":"2007","journal-title":"J Burn Care Res"},{"key":"10.1016\/j.medin.2016.02.001_bib0195","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1093\/jac\/44.3.319","article-title":"Pharmacokinetics of antibiotics in burn patients","volume":"44","author":"Weinbren","year":"1999","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.medin.2016.02.001_bib0200","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1097\/BCR.0B013E318031AA44","article-title":"Inflammation and the Host Response to Trauma. Collaborative Research Program. Standard operating procedures for the clinical management of patients enrolled in a prospective study of Inflammation and the Host Response to Thermal Injury","volume":"28","author":"Silver","year":"2007","journal-title":"J Burn Care Res"},{"key":"10.1016\/j.medin.2016.02.001_bib0205","doi-asserted-by":"crossref","first-page":"63","DOI":"10.3109\/02844317909013023","article-title":"The prevention of wound infections in burn patients","volume":"13","author":"Van Saene","year":"1979","journal-title":"Scand J Plast Reconstr Surg"},{"key":"10.1016\/j.medin.2016.02.001_bib0210","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1016\/S0213-005X(03)73008-0","article-title":"Timing of bacterial colonization in severe burns: is strict isolation necessary?","volume":"21","author":"Barret","year":"2003","journal-title":"Enferm Infecc Microbiol Clin"},{"key":"10.1016\/j.medin.2016.02.001_bib0215","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1097\/01.sla.0000154148.58154.d5","article-title":"Survival benefit in critically ill burned patients receiving selective decontamination of the digestive tract: a randomized, placebo-controlled, double-blind trial","volume":"241","author":"de la Cal","year":"2005","journal-title":"Ann Surg"},{"key":"10.1016\/j.medin.2016.02.001_bib0220","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/S0210-5691(07)74792-7","article-title":"Selective digestive decontamination. Why don\u2019t we apply the evidence in the clinical practice?","volume":"31","author":"Taylor","year":"2007","journal-title":"Med Intensiva"},{"key":"10.1016\/j.medin.2016.02.001_bib0225","doi-asserted-by":"crossref","first-page":"1160","DOI":"10.1378\/chest.119.4.1160","article-title":"Pneumonia in patients with severe burns: a classification according to the concept of the carrier state","volume":"119","author":"de la Cal","year":"2001","journal-title":"Chest"},{"key":"10.1016\/j.medin.2016.02.001_bib0230","article-title":"Antibiotic prophylaxis to reduce respiratory tract infections and mortality in adults receiving intensive care","volume":"7","author":"Liberati","year":"2009","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.medin.2016.02.001_bib0235","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.jhin.2006.10.014","article-title":"Selective decontamination of the digestive tract reduces bacterial bloodstream infection and mortality in critically ill patients. Systematic review of randomized, controlled trials","volume":"65","author":"Silvestri","year":"2007","journal-title":"J Hosp Infect"},{"key":"10.1016\/j.medin.2016.02.001_bib0240","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1016\/S1473-3099(11)70035-4","article-title":"Selective digestive tract decontamination and selective oropharyngeal decontamination and antibiotic resistance in patients in intensive-care units: an open-label, clustered group-randomised, crossover study","volume":"11","author":"de Smet","year":"2011","journal-title":"Lancet Infect Dis"},{"key":"10.1016\/j.medin.2016.02.001_bib0245","doi-asserted-by":"crossref","first-page":"873","DOI":"10.7326\/0003-4819-110-11-873","article-title":"Intestinal decontamination for control of nosocomial multiresistant gram-negative bacilli. Study of an outbreak in an intensive care unit","volume":"110","author":"Brun-Buissom","year":"1989","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.medin.2016.02.001_bib0250","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1097\/00005373-199205000-00006","article-title":"Prevention of infection in burns: preliminary experience with selective decontamination of the digestive tract in patients with extensive injuries","volume":"32","author":"Mackie","year":"1992","journal-title":"J Trauma"},{"key":"10.1016\/j.medin.2016.02.001_bib0255","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1097\/01.sla.0000250418.14359.31","article-title":"Enteral vancomycin controls methicillin-resistant Staphylococcus aureus endemicity in an intensive care burn unit: a 9 year prospective study","volume":"245","author":"Cerd\u00e1","year":"2007","journal-title":"Ann Surg"},{"key":"10.1016\/j.medin.2016.02.001_bib0260","series-title":"National Burn Repository 2015. Version 11.0. Report of data from 2005\u20132014","first-page":"82","author":"American Burn Association","year":"2015"},{"key":"10.1016\/j.medin.2016.02.001_bib0265","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1097\/BCR.0b013e3181e4d5e7","article-title":"Epidemiology of bloodstream infections in burn-injured patients: a review of the national burn repository","volume":"31","author":"Shupp","year":"2010","journal-title":"J Burn Care Res"},{"key":"10.1016\/j.medin.2016.02.001_bib0270","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1016\/j.ajic.2014.11.014","article-title":"National Healthcare Safety Network report, data summary for 2013, Device-associated Module","volume":"43","author":"Dudeck","year":"2015","journal-title":"Am J Infect Control"},{"key":"10.1016\/j.medin.2016.02.001_bib0275","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1097\/00004630-200207000-00007","article-title":"Catheter infection risk related to the distance between insertion site and burned area","volume":"23","author":"Ramos","year":"2002","journal-title":"J Burn Care Rehabil"},{"key":"10.1016\/j.medin.2016.02.001_bib0280","doi-asserted-by":"crossref","first-page":"2725","DOI":"10.1056\/NEJMoa061115","article-title":"An Intervention to decrease catheter-related bloodstream infections in the ICU","volume":"355","author":"Pronovost","year":"2006","journal-title":"N Engl J Med"},{"key":"10.1016\/j.medin.2016.02.001_bib0285","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1128\/CMR.19.2.403-434.2006","article-title":"Burn wound infections","volume":"19","author":"Church","year":"2006","journal-title":"Clin Microbiol Rev"},{"key":"10.1016\/j.medin.2016.02.001_bib0290","series-title":"White paper surgical management of the burn wound and use of skin substitutes","author":"Kagan","year":"2009"},{"key":"10.1016\/j.medin.2016.02.001_bib0295","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1016\/j.burns.2008.05.012","article-title":"Pernicious effectors in burns","volume":"34","author":"Alg\u00f6wer","year":"2008","journal-title":"Burns"},{"key":"10.1016\/j.medin.2016.02.001_bib0300","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.burns.2005.09.005","article-title":"Meta-analysis of early excision of burns","volume":"32","author":"Ong","year":"2006","journal-title":"Burns"},{"key":"10.1016\/j.medin.2016.02.001_bib0305","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1016\/j.burns.2005.04.012","article-title":"Burn care standards in Israel: lack of consensus","volume":"31","author":"Haik","year":"2005","journal-title":"Burns"},{"key":"10.1016\/j.medin.2016.02.001_bib0310","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1097\/01.BCR.0000203493.31642.79","article-title":"Infection control practices in U.S. burn units","volume":"27","author":"Hodle","year":"2006","journal-title":"J Burn Care Res"},{"key":"10.1016\/j.medin.2016.02.001_bib0315","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1097\/00004630-199809000-00005","article-title":"Surveillance of burn wound infections: a proposal for definitions","volume":"19","author":"Peck","year":"1998","journal-title":"J Burn Care Rehabil"},{"key":"10.1016\/j.medin.2016.02.001_bib0320","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1016\/j.burns.2009.06.201","article-title":"Limb intracompartmental sepsis in burn patients associated with occult infection","volume":"36","author":"Pe\u00f1uelas","year":"2010","journal-title":"Burns"},{"key":"10.1016\/j.medin.2016.02.001_bib0325","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1001\/archsurg.1987.01400130080012","article-title":"Comparison of quantitative microbiology and histopathology in divided burn-wound biopsy specimens","volume":"122","author":"McManus","year":"1987","journal-title":"Arch Surg"},{"key":"10.1016\/j.medin.2016.02.001_bib0330","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1097\/00004630-198909000-00008","article-title":"Leukopenia in acute thermal injury: evidence against topical silver sulfadiazine as the causative agent","volume":"10","author":"Thomson","year":"1989","journal-title":"J Burn Care Rehabil"},{"key":"10.1016\/j.medin.2016.02.001_bib0335","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1097\/BCR.0b013e3181a28c9b","article-title":"The side effects of silver sulfadiazine","volume":"30","author":"Fuller","year":"2009","journal-title":"J Burn Care Res"},{"key":"10.1016\/j.medin.2016.02.001_bib0340","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.burns.2006.07.014","article-title":"Predictors of mortality: a comparison between two burn wound treatment policies","volume":"33","author":"Vehmeyer-Heeman","year":"2007","journal-title":"Burns"},{"key":"10.1016\/j.medin.2016.02.001_bib0345","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1016\/j.burns.2013.07.008","article-title":"Aquacel\u00ae Ag dressing versus Acticoat\u2122 dressing in partial thickness burns: a prospective, randomized, controlled study in 100 patients. Part 1: burn wound healing","volume":"40","author":"Verbelen","year":"2014","journal-title":"Burns"},{"key":"10.1016\/j.medin.2016.02.001_bib0350","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/j.burns.2011.09.020","article-title":"A systematic review of silver-containing dressings and topical silver agents (used with dressings) for burn wounds","volume":"38","author":"Aziz","year":"2012","journal-title":"Burns"},{"key":"10.1016\/j.medin.2016.02.001_bib0355","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1016\/j.burns.2010.04.013","article-title":"Use of procalcitonin for the detection of sepsis in the critically ill burn patient: a systematic review of the literature","volume":"37","author":"Mann","year":"2011","journal-title":"Burns"},{"key":"10.1016\/j.medin.2016.02.001_bib0360","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1097\/BCR.0000000000000147","article-title":"Pharmacokinetics and pharmacodynamics of antibacterial and antifungal agents in adult patients with thermal injury: a review of current literature","volume":"36","author":"Ortwine","year":"2015","journal-title":"J Burn Care Res"}],"container-title":["Medicina Intensiva"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S021056911600053X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S021056911600053X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,14]],"date-time":"2018-09-14T05:00:20Z","timestamp":1536901220000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S021056911600053X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,4]]},"references-count":36,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2016,4]]}},"alternative-id":["S021056911600053X"],"URL":"https:\/\/doi.org\/10.1016\/j.medin.2016.02.001","relation":{},"ISSN":["0210-5691"],"issn-type":[{"value":"0210-5691","type":"print"}],"subject":[],"published":{"date-parts":[[2016,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Infections in critically ill burn patients","name":"articletitle","label":"Article Title"},{"value":"Medicina Intensiva","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.medin.2016.02.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2016 Published by Elsevier Espa\u00f1a, S.L.","name":"copyright","label":"Copyright"}]}}