{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T02:24:13Z","timestamp":1783650253378,"version":"3.55.0"},"reference-count":37,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.es","elsevier.es","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Medicina Intensiva"],"published-print":{"date-parts":[[2017,1]]},"DOI":"10.1016\/j.medin.2016.07.010","type":"journal-article","created":{"date-parts":[[2016,10,27]],"date-time":"2016-10-27T04:46:22Z","timestamp":1477543582000},"page":"21-27","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":23,"title":["Association between exposure to angiotensin-converting enzyme inhibitors and angiotensin receptor blockers prior to septic shock and acute kidney injury"],"prefix":"10.1016","volume":"41","author":[{"given":"B.","family":"Suberviola","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Rodrigo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Gonz\u00e1lez-Castro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Serrano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Heras","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00c1.","family":"Castellanos-Ortega","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.medin.2016.07.010_bib0190","doi-asserted-by":"crossref","first-page":"3365","DOI":"10.1681\/ASN.2004090740","article-title":"Acute kidney injury, mortality, length of stay, and costs in hospitalized patients","volume":"16","author":"Chertow","year":"2005","journal-title":"J Am Soc Nephrol"},{"key":"10.1016\/j.medin.2016.07.010_bib0195","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.ccc.2011.10.006","article-title":"The economics of renal failure and kidney disease in critically ill patients","volume":"28","author":"Parikh","year":"2012","journal-title":"Crit Care Clin."},{"key":"10.1016\/j.medin.2016.07.010_bib0200","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1159\/000337487","article-title":"Acute kidney injury and mortality in hospitalized patients","volume":"35","author":"Wang","year":"2012","journal-title":"Am J Nephrol."},{"key":"10.1016\/j.medin.2016.07.010_bib0205","doi-asserted-by":"crossref","first-page":"2659","DOI":"10.1097\/CCM.0b013e3182281f1b","article-title":"Outcome of critically ill patients with acute kidney injury using the Acute Kidney Injury Network criteria","volume":"39","author":"Mandelbaum","year":"2011","journal-title":"Crit Care Med."},{"key":"10.1016\/j.medin.2016.07.010_bib0210","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1001\/jama.294.7.813","article-title":"Acute renal failure in critically ill patients: a multinational, multicenter study","volume":"294","author":"Uchino","year":"2005","journal-title":"JAMA"},{"key":"10.1016\/j.medin.2016.07.010_bib0215","doi-asserted-by":"crossref","first-page":"431","DOI":"10.2215\/CJN.03681106","article-title":"Septic acute kidney injury in critically ill patients: clinical characteristics and outcomes","volume":"2","author":"Bagshaw","year":"2007","journal-title":"Clin J Am Soc Nephrol"},{"key":"10.1016\/j.medin.2016.07.010_bib0220","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1111\/bcp.12419","article-title":"Antihypertensive agents acting on the renin-angiotensin system and the risk of sepsis","volume":"78","author":"Dial","year":"2014","journal-title":"Br J Clin Pharmacol"},{"key":"10.1016\/j.medin.2016.07.010_bib0225","doi-asserted-by":"crossref","first-page":"F807","DOI":"10.1152\/ajprenal.00266.2015","article-title":"Twenty years after ACEIs and ARBs: emerging treatment strategies for diabetic nephropathy","volume":"309","author":"Johnson","year":"2015","journal-title":"Am J Physiol Renal Physiol"},{"key":"10.1016\/j.medin.2016.07.010_bib0230","doi-asserted-by":"crossref","first-page":"2787","DOI":"10.1093\/ndt\/gft405","article-title":"Preoperative angiotensin-converting enzyme inhibitors and angiotensin receptor blocker use and acute kidney injury in patients undergoing cardiac surgery","volume":"28","author":"Coca","year":"2013","journal-title":"Nephrol Dial Transpl"},{"key":"10.1016\/j.medin.2016.07.010_bib0235","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1186\/1471-2369-15-53","article-title":"Association between angiotensin converting enzyme inhibitor angiotensin receptor blocker use prior to major elective surgery and the risk of acute dialysis","volume":"15","author":"Shah","year":"2014","journal-title":"BMC Nephrol."},{"key":"10.1016\/j.medin.2016.07.010_bib0240","doi-asserted-by":"crossref","first-page":"1744","DOI":"10.2215\/CJN.05480610","article-title":"Predictors of acute kidney injury in septic shock patients: an observational cohort study","volume":"6","author":"Plataki","year":"2011","journal-title":"Clin J Am Soc Nephrol."},{"key":"10.1016\/j.medin.2016.07.010_bib0245","series-title":"Acute kidney injury: prevention, detection and management up to the point of renal replacement therapy","author":"National Clinical Guideline Centre (UK)","year":"2013"},{"key":"10.1016\/j.medin.2016.07.010_bib0250","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1097\/SHK.0b013e3182360f7c","article-title":"Late compliance with the sepsis resuscitation bundle: impact on mortality","volume":"36","author":"Castellanos-Ortega","year":"2011","journal-title":"Shock"},{"key":"10.1016\/j.medin.2016.07.010_bib0255","doi-asserted-by":"crossref","first-page":"1250","DOI":"10.1097\/01.CCM.0000050454.01978.3B","article-title":"SCCM\/ESICM\/ACCP\/ATS\/SIS. 2001 SCCM\/ESICM\/ACCP\/ATS\/SIS International Sepsis Definitions Conference","volume":"31","author":"Levy","year":"2003","journal-title":"Crit Care Med"},{"key":"10.1016\/j.medin.2016.07.010_bib0260","doi-asserted-by":"crossref","first-page":"1368","DOI":"10.1056\/NEJMoa010307","article-title":"Early goal-directed therapy in the treatment of severe sepsis and septic shock","volume":"345","author":"Rivers","year":"2001","journal-title":"N Engl J Med."},{"key":"10.1016\/j.medin.2016.07.010_bib0265","first-page":"1","article-title":"KDIGO clinical practice guideline for acute kidney injury","volume":"2","year":"2012","journal-title":"Kidney Int Suppl"},{"key":"10.1016\/j.medin.2016.07.010_bib0270","doi-asserted-by":"crossref","first-page":"12","DOI":"10.2215\/CJN.02730313","article-title":"Incidence, outcomes, and comparisons across definitions of AKI in hospitalized individuals","volume":"9","author":"Zeng","year":"2014","journal-title":"Clin J Am Soc Nephrol"},{"key":"10.1016\/j.medin.2016.07.010_bib0275","doi-asserted-by":"crossref","first-page":"848","DOI":"10.2215\/CJN.09530913","article-title":"Validation of the Kidney Disease Improving Global Outcomes criteria for AKI and comparison of three criteria in hospitalized patients","volume":"9","author":"Fujii","year":"2014","journal-title":"Clin J Am Soc Nephrol."},{"key":"10.1016\/j.medin.2016.07.010_bib0280","doi-asserted-by":"crossref","first-page":"1837","DOI":"10.1097\/01.CCM.0000277041.13090.0A","article-title":"Acute kidney injury in the intensive care unit according to RIFLE","volume":"35","author":"Ostermann","year":"2007","journal-title":"Crit Care Med."},{"key":"10.1016\/j.medin.2016.07.010_bib0285","doi-asserted-by":"crossref","first-page":"S169","DOI":"10.1097\/CCM.0b013e3181de0c60","article-title":"Drug-induced acute kidney injury in the critically ill adult: recognition and prevention strategies","volume":"38","author":"Bentley","year":"2010","journal-title":"Crit. Care Med."},{"key":"10.1016\/j.medin.2016.07.010_bib0290","doi-asserted-by":"crossref","first-page":"S216","DOI":"10.1097\/CCM.0b013e318168e375","article-title":"An overview of drug-induced acute kidney injury","volume":"36","author":"Pannu","year":"2008","journal-title":"Crit. Care Med."},{"key":"10.1016\/j.medin.2016.07.010_bib0295","doi-asserted-by":"crossref","first-page":"965","DOI":"10.3349\/ymj.2013.54.4.965","article-title":"Acute kidney injury in patients with sepsis and septic shock: risk factors and clinical outcomes","volume":"54","author":"Suh","year":"2013","journal-title":"Yonsei Med J."},{"key":"10.1016\/j.medin.2016.07.010_bib0300","doi-asserted-by":"crossref","first-page":"1619","DOI":"10.1592\/phco.27.12.1619","article-title":"Impact of previous statin and angiotensin II receptor blocker use on mortality in patients hospitalized with sepsis","volume":"27","author":"Mortensen","year":"2007","journal-title":"Pharmacotherapy"},{"key":"10.1016\/j.medin.2016.07.010_bib0305","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1517\/14728220903460332","article-title":"Modulation of the renin-angiotensin-aldosterone system in sepsis: a new therapeutic approach","volume":"14","author":"Salgado","year":"2010","journal-title":"Expert Opin. Ther. Targets"},{"key":"10.1016\/j.medin.2016.07.010_bib0310","doi-asserted-by":"crossref","first-page":"1342","DOI":"10.3892\/etm.2014.1566","article-title":"Severe sepsis: low expression of the renin-angiotensin system is associated with poor prognosis","volume":"7","author":"Zhang","year":"2014","journal-title":"Exp Ther Med."},{"key":"10.1016\/j.medin.2016.07.010_bib0315","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1016\/j.jcrc.2011.04.005","article-title":"Analysis of progression in risk, injury, failure, loss, and end-stage renal disease classification on outcome in patients with severe sepsis and septic shock","volume":"27","author":"Kim","year":"2012","journal-title":"J Crit Care."},{"key":"10.1016\/j.medin.2016.07.010_bib0320","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1111\/aas.12133","article-title":"Acute kidney injury in patients with severe sepsis in Finnish Intensive Care Units","volume":"57","author":"Poukkanen","year":"2013","journal-title":"Acta Anaesthesiol Scand"},{"key":"10.1016\/j.medin.2016.07.010_bib0325","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1097\/CCM.0000000000000706","article-title":"The association of acute kidney injury in the critically ill and postdischarge outcomes: a cohort study","volume":"43","author":"Horkan","year":"2015","journal-title":"Crit Care Med."},{"key":"10.1016\/j.medin.2016.07.010_bib0330","doi-asserted-by":"crossref","first-page":"904","DOI":"10.1093\/ndt\/gfm610","article-title":"Acute renal failure in patients with severe sepsis and septic shock \u2013 a significant independent risk factor for mortality: results from the German Prevalence Study","volume":"23","author":"Oppert","year":"2008","journal-title":"Nephrol Dial Transpl"},{"key":"10.1016\/j.medin.2016.07.010_bib0335","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1016\/j.ccc.2015.06.003","article-title":"Sepsis-induced acute kidney injury","volume":"31","author":"M\u00e5rtensson","year":"2015","journal-title":"Crit Care Clin."},{"key":"10.1016\/j.medin.2016.07.010_bib0340","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1016\/j.jcrc.2014.04.003","article-title":"Early reversible acute kidney injury is associated with improved survival in septic shock","volume":"29","author":"Sood","year":"2014","journal-title":"J Crit Care."},{"key":"10.1016\/j.medin.2016.07.010_bib0345","doi-asserted-by":"crossref","first-page":"1036","DOI":"10.1097\/CCM.0b013e3181d455b6","article-title":"Impact of the surviving sepsis campaign protocols on hospital length of stay and mortality in septic shock patients: results of a three-year follow-up quasi-experimental study","volume":"38","author":"Castellanos-Ortega","year":"2010","journal-title":"Crit Care Med."},{"key":"10.1016\/j.medin.2016.07.010_bib0350","doi-asserted-by":"crossref","first-page":"S198","DOI":"10.1097\/CCM.0b013e318168ccd5","article-title":"Pathophysiology of septic acute kidney injury: what do we really know?","volume":"36","author":"Wan","year":"2008","journal-title":"Crit. Care Med."},{"key":"10.1016\/j.medin.2016.07.010_bib0355","doi-asserted-by":"crossref","first-page":"544","DOI":"10.4103\/1319-2442.132171","article-title":"Outcome of patients with acute kidney injury in severe sepsis and septic shock treated with early goal-directed therapy in an intensive care unit","volume":"25","author":"Ahmed","year":"2014","journal-title":"Saudi J Kidney Dis Transpl."},{"key":"10.1016\/j.medin.2016.07.010_bib0360","doi-asserted-by":"crossref","first-page":"1301","DOI":"10.1056\/NEJMoa1500896","article-title":"Trial of early, goal-directed resuscitation for septic shock","volume":"372","author":"Mouncey","year":"2015","journal-title":"N Engl J Med"},{"key":"10.1016\/j.medin.2016.07.010_bib0365","doi-asserted-by":"crossref","first-page":"1683","DOI":"10.1056\/NEJMoa1401602","article-title":"A randomized trial of protocol-based care for early septic shock","volume":"370","author":"Yealy","year":"2014","journal-title":"N Engl J Med"},{"key":"10.1016\/j.medin.2016.07.010_bib0370","doi-asserted-by":"crossref","first-page":"1496","DOI":"10.1056\/NEJMoa1404380","article-title":"Goal-directed resuscitation for patients with early septic shock","volume":"371","author":"ARISE Investigators","year":"2014","journal-title":"N Engl J Med"}],"container-title":["Medicina Intensiva"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0210569116301760?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0210569116301760?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,9,15]],"date-time":"2019-09-15T02:33:37Z","timestamp":1568514817000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0210569116301760"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,1]]},"references-count":37,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,1]]}},"alternative-id":["S0210569116301760"],"URL":"https:\/\/doi.org\/10.1016\/j.medin.2016.07.010","relation":{},"ISSN":["0210-5691"],"issn-type":[{"value":"0210-5691","type":"print"}],"subject":[],"published":{"date-parts":[[2017,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Association between exposure to angiotensin-converting enzyme inhibitors and angiotensin receptor blockers prior to septic shock and acute kidney injury","name":"articletitle","label":"Article Title"},{"value":"Medicina Intensiva","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.medin.2016.07.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Espa\u00f1a, S.L.U. y SEMICYUC. All rights reserved.","name":"copyright","label":"Copyright"}]}}