{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T02:58:20Z","timestamp":1769050700044,"version":"3.49.0"},"reference-count":37,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.es","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Medicina Intensiva (English Edition)"],"published-print":{"date-parts":[[2022,1]]},"DOI":"10.1016\/j.medine.2021.11.005","type":"journal-article","created":{"date-parts":[[2021,11,19]],"date-time":"2021-11-19T12:01:09Z","timestamp":1637323269000},"page":"1-7","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Clinico-radiological related to early brain death factors"],"prefix":"10.1016","volume":"46","author":[{"given":"D.","family":"Escudero","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I.","family":"Astola","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Balboa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Leoz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00c1.","family":"Meilan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"del Busto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Quind\u00f3s","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Forcelledo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Vizcaino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Mart\u00edn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Salgado","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Vi\u00f1a","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.medine.2021.11.005_bib0005","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/S0210-5691(09)71215-X","article-title":"Diagn\u00f3stico de muerte encef\u00e1lica","volume":"33","author":"Escudero","year":"2009","journal-title":"Med Intensiva"},{"key":"10.1016\/j.medine.2021.11.005_bib0010","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/B978-0-444-64142-7.00042-4","article-title":"Brain death","volume":"161","author":"Koenig","year":"2019","journal-title":"Handb Clin Neurol"},{"key":"10.1016\/j.medine.2021.11.005_bib0015","doi-asserted-by":"crossref","first-page":"1130","DOI":"10.1111\/anae.13065","article-title":"Intensive care practices in brain death diagnosis and organ donation","volume":"70","author":"Escudero","year":"2015","journal-title":"Anaesthesia"},{"key":"10.1016\/j.medine.2021.11.005_bib0020","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1016\/j.medin.2014.11.005","article-title":"Doppler transcraneal en el diagn\u00f3stico de la muerte encef\u00e1lica. \u00bfEs \u00fatil o retrasa el diagn\u00f3stico?","volume":"39","author":"Escudero","year":"2015","journal-title":"Med Intensiva"},{"key":"10.1016\/j.medine.2021.11.005_bib0025","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1007\/s12028-009-9243-7","article-title":"Diagnosing brain death by CT perfusion and multislice CT angiography","volume":"11","author":"Escudero","year":"2009","journal-title":"Neurocrit Care"},{"key":"10.1016\/j.medine.2021.11.005_bib0030","author":"Organizaci\u00f3n Nacional de Trasplante"},{"key":"10.1016\/j.medine.2021.11.005_bib0035","doi-asserted-by":"crossref","first-page":"1387","DOI":"10.1007\/s00134-014-3398-1","article-title":"Reglaze your glasses! The unused potential of organ donors in times of high demand","volume":"40","author":"Kompanje","year":"2014","journal-title":"Intensive Care Med"},{"key":"10.1016\/j.medine.2021.11.005_bib0040","doi-asserted-by":"crossref","first-page":"2507","DOI":"10.1111\/j.1600-6143.2012.04138.x","article-title":"Continuously evaluating performance in deceased donation: the Spanish quality assurance program","volume":"12","author":"De la Rosa","year":"2012","journal-title":"Am J Transplant"},{"key":"10.1016\/j.medine.2021.11.005_bib0045","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1001\/jama.290.6.790","article-title":"End-of-life practices in European intensive care units: the Ethicus Study","volume":"290","author":"Sprung","year":"2003","journal-title":"JAMA"},{"key":"10.1016\/j.medine.2021.11.005_bib0050","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1111\/tri.12084","article-title":"Prediction of evolution toward brain death upon admission to ICU in comatose patients with spontaneous hemorrhage using simple signs","volume":"26","author":"Galbois","year":"2013","journal-title":"Transpl Int"},{"key":"10.1016\/j.medine.2021.11.005_bib0055","doi-asserted-by":"crossref","first-page":"1257","DOI":"10.1016\/S0140-6736(18)31878-6","article-title":"Intracerebral haemorrhage: current approaches to acute management","volume":"392","author":"Cordonnier","year":"2018","journal-title":"Lancet"},{"key":"10.1016\/j.medine.2021.11.005_bib0060","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1111\/tri.12695","article-title":"Predictive factors of brain death in severe stroke patients identified by organ procurement and transplant coordination in Lorrain, France","volume":"29","author":"Humbertjean","year":"2016","journal-title":"Transpl Int"},{"key":"10.1016\/j.medine.2021.11.005_bib0065","doi-asserted-by":"crossref","first-page":"1409","DOI":"10.1161\/STROKEAHA.118.024403","article-title":"Determinants of early versus delayed neurological deterioration in intracerebral hemorrhage","volume":"50","author":"You","year":"2019","journal-title":"Stroke"},{"key":"10.1016\/j.medine.2021.11.005_bib0070","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1007\/s12028-019-00841-1","article-title":"Predicting malignant cerebral edema after large hemispheric stroke","volume":"32","author":"Kimberly","year":"2020","journal-title":"Neurocrit Care"},{"key":"10.1016\/j.medine.2021.11.005_bib0075","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.jns.2014.06.057","article-title":"Hematoma volume as the major determinant of outcomes after intracerebral hemorrhage","volume":"345","author":"LoPresti","year":"2014","journal-title":"J Neurol Sci"},{"key":"10.1016\/j.medine.2021.11.005_bib0080","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1016\/j.medin.2015.01.008","article-title":"Medicina Intensiva y donaci\u00f3n de \u00f3rganos. \u00bfExplorando las \u00faltimas fronteras?","volume":"39","author":"Escudero","year":"2015","journal-title":"Med Intensiva"},{"key":"10.1016\/j.medine.2021.11.005_bib0085","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1161\/STROKEAHA.118.023902","article-title":"Prediction of outcome after aneurysmal subarachnoid hemorrhage","volume":"50","author":"Van Donkelaar","year":"2019","journal-title":"Stroke"},{"key":"10.1016\/j.medine.2021.11.005_bib0090","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1161\/01.STR.32.4.891","article-title":"The ICH score: a simple, reliable grading scale for intracerebral hemorrhage","volume":"32","author":"Hemphill","year":"2001","journal-title":"Stroke"},{"key":"10.1016\/j.medine.2021.11.005_bib0095","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1007\/s12028-015-0137-6","article-title":"Recommendations for the critical care management of devastating brain injury: prognostication, psychosocial, and ethical management. A position statement for healthcare professionals from the neurocritical care society","volume":"23","author":"Souter","year":"2015","journal-title":"Neurocrit Care"},{"key":"10.1016\/j.medine.2021.11.005_bib0100","doi-asserted-by":"crossref","first-page":"1887","DOI":"10.1161\/STR.0000000000000015","article-title":"Palliative and end-of-life care in stroke: a statement for healthcare professionals from the American Heart Association\/American Stroke Association","volume":"45","author":"Holloway","year":"2014","journal-title":"Stroke"},{"key":"10.1016\/j.medine.2021.11.005_bib0105","doi-asserted-by":"crossref","first-page":"1488","DOI":"10.1007\/s00134-010-1848-y","article-title":"Imminent brain death: point of departure for potential heart-beating organ donor recognition","volume":"36","author":"De Groot","year":"2010","journal-title":"Intensive Care Med"},{"key":"10.1016\/j.medine.2021.11.005_bib0110","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1111\/j.1432-2277.2012.01505.x","article-title":"Imprecise definitions of starting points in retrospectively reviewing potential organ donors causes confusion: call for a reproducible method like \u2018imminent brain death\u2019","volume":"25","author":"Jansen","year":"2012","journal-title":"Transpl Int"},{"key":"10.1016\/j.medine.2021.11.005_bib0115","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1212\/WNL.59.2.205","article-title":"Long-term prognosis after recovery from primary intracerebral hemorrhage","volume":"59","author":"Vermeer","year":"2002","journal-title":"Neurology"},{"key":"10.1016\/j.medine.2021.11.005_bib0120","doi-asserted-by":"crossref","first-page":"2175","DOI":"10.1161\/01.STR.31.9.2175","article-title":"Prediction of malignant middle cerebral artery infarction by diffusion-weighted imaging","volume":"31","author":"Oppenheim","year":"2000","journal-title":"Stroke"},{"key":"10.1016\/j.medine.2021.11.005_bib0125","doi-asserted-by":"crossref","first-page":"1283","DOI":"10.1227\/01.NEU.0000093825.04365.F3","article-title":"Primary intracerebral hemorrhage in Izumo City, Japan: incidence rates and outcome in relation to the site of hemorrhage","volume":"53","author":"Inagawa","year":"2003","journal-title":"Neurosurgery"},{"key":"10.1016\/j.medine.2021.11.005_bib0130","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1161\/01.STR.24.7.987","article-title":"Volume of intracerebral hemorrhage. A powerful and easy-to-use predictor of 30-day mortality","volume":"24","author":"Broderick","year":"1993","journal-title":"Stroke"},{"key":"10.1016\/j.medine.2021.11.005_bib0135","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13054-016-1432-0","article-title":"The critical care management of spontaneous intracranial hemorrhage: a contemporary review","volume":"20","author":"De Oliveira Manoel","year":"2016","journal-title":"Crit Care"},{"key":"10.1016\/j.medine.2021.11.005_bib0140","doi-asserted-by":"crossref","first-page":"341","DOI":"10.3340\/jkns.2009.45.6.341","article-title":"Predictors of 30-day mortality and 90-day functional recovery after primary intracerebral hemorrhage: hospital based multivariate analysis in 585 patients","volume":"45","author":"Kim","year":"2009","journal-title":"J Korean Neurosurg Soc"},{"key":"10.1016\/j.medine.2021.11.005_bib0145","doi-asserted-by":"crossref","first-page":"1295","DOI":"10.1001\/jama.2019.2413","article-title":"Cerebral intraparenchymal hemorrhage: a review","volume":"321","author":"Gross","year":"2019","journal-title":"JAMA"},{"key":"10.1016\/j.medine.2021.11.005_bib0150","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1186\/s13054-020-2749-2","article-title":"Surgery for spontaneous intracerebral hemorrhage","volume":"24","author":"de Oliveira Manoel","year":"2020","journal-title":"Crit Care"},{"key":"10.1016\/j.medine.2021.11.005_bib0155","doi-asserted-by":"crossref","first-page":"e667","DOI":"10.1097\/SCS.0000000000005733","article-title":"Factors affecting prognosis in patients with spontaneous supratentorial intracerebral hemorrhage under medical and surgical treatment","volume":"30","author":"Akpinar","year":"2019","journal-title":"J Craniofac Surg"},{"key":"10.1016\/j.medine.2021.11.005_bib0160","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/j.medin.2014.07.010","article-title":"Potencialidad de donaci\u00f3n de \u00f3rganos en muerte encef\u00e1lica y limitaci\u00f3n del tratamiento de soporte vital en los pacientes neurocr\u00edticos","volume":"39","author":"Bod\u00ed","year":"2015","journal-title":"Med Intensiva"},{"key":"10.1016\/j.medine.2021.11.005_bib0165","doi-asserted-by":"crossref","first-page":"1257","DOI":"10.1161\/01.STR.0000259633.59404.f3","article-title":"CT angiography \u201cSpot Sign\u201d predicts hematoma expansi\u00f3n in acute intracerebral hemorrhage","volume":"38","author":"Wada","year":"2007","journal-title":"Stroke"},{"key":"10.1016\/j.medine.2021.11.005_bib0170","doi-asserted-by":"crossref","first-page":"1267","DOI":"10.1007\/s00134-014-3392-7","article-title":"Optic nerve sheath diameter on computed tomography is correlated with simultaneously measured intracranial pressure in patients with severe traumatic brain injury","volume":"40","author":"Sekhon","year":"2014","journal-title":"Intensive Care Med"},{"key":"10.1016\/j.medine.2021.11.005_bib0175","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1186\/1746-160X-10-32","article-title":"Quantitative relations between the eyeball, the optic nerve, and the optic canal important for intracranial pressure monitoring","volume":"10","author":"Vaiman","year":"2014","journal-title":"Head Face Med"},{"key":"10.1016\/j.medine.2021.11.005_bib0180","doi-asserted-by":"crossref","first-page":"1782","DOI":"10.1111\/ajt.15253","article-title":"Summary of Spanish recommendations on Intensive Care to facilitate organ donation","volume":"19","author":"Mart\u00edn-Delgado","year":"2019","journal-title":"Am J Transplant"},{"key":"10.1016\/j.medine.2021.11.005_bib0185","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1097\/CCM.0b013e318198683a","article-title":"The IVH score: a novel tool for estimating intraventricular hemorrhage volume: clinical and research implications","volume":"37","author":"Hallevi","year":"2009","journal-title":"Crit Care Med"}],"container-title":["Medicina Intensiva (English Edition)"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S217357272100148X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S217357272100148X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T02:34:40Z","timestamp":1761878080000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S217357272100148X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1]]},"references-count":37,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,1]]}},"alternative-id":["S217357272100148X"],"URL":"https:\/\/doi.org\/10.1016\/j.medine.2021.11.005","relation":{},"ISSN":["2173-5727"],"issn-type":[{"value":"2173-5727","type":"print"}],"subject":[],"published":{"date-parts":[[2022,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Clinico-radiological related to early brain death factors","name":"articletitle","label":"Article Title"},{"value":"Medicina Intensiva (English Edition)","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.medine.2021.11.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Espa\u00f1a,  S.L.U. and SEMICYUC. All rights reserved.","name":"copyright","label":"Copyright"}]}}