{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T06:36:05Z","timestamp":1791959765997,"version":"4.3.4"},"reference-count":55,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,4,20]],"date-time":"2025-04-20T00:00:00Z","timestamp":1745107200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100019081","name":"Science and Technology Program of Hunan Province","doi-asserted-by":"publisher","award":["2023RC4005"],"award-info":[{"award-number":["2023RC4005"]}],"id":[{"id":"10.13039\/501100019081","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82301332"],"award-info":[{"award-number":["82301332"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82225014"],"award-info":[{"award-number":["82225014"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82171148"],"award-info":[{"award-number":["82171148"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82192864"],"award-info":[{"award-number":["82192864"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003399","name":"Science and Technology Commission of Shanghai Municipality","doi-asserted-by":"publisher","award":["23J31900100"],"award-info":[{"award-number":["23J31900100"]}],"id":[{"id":"10.13039\/501100003399","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003024","name":"Shanghai Education Development Foundation","doi-asserted-by":"publisher","award":["22CGA09"],"award-info":[{"award-number":["22CGA09"]}],"id":[{"id":"10.13039\/501100003024","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003395","name":"Shanghai Municipal Education Commission","doi-asserted-by":"publisher","award":["2023ZKZD12"],"award-info":[{"award-number":["2023ZKZD12"]}],"id":[{"id":"10.13039\/501100003395","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2020YFA0908201"],"award-info":[{"award-number":["2020YFA0908201"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Med"],"published-print":{"date-parts":[[2025,8]]},"DOI":"10.1016\/j.medj.2025.100696","type":"journal-article","created":{"date-parts":[[2025,5,22]],"date-time":"2025-05-22T10:33:39Z","timestamp":1747910019000},"page":"100696","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"title":["Audiological characteristics following gene therapy in patients with autosomal recessive deafness 9"],"prefix":"10.1016","volume":"6","author":[{"given":"Longlong","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dingding","family":"Dong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanbo","family":"Yin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Honghai","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Lv","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qi","family":"Cao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wuqing","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bing","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunfeng","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huawei","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daqi","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8893-434X","authenticated-orcid":false,"given":"Yilai","family":"Shu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.medj.2025.100696_bib1","unstructured":"WHO (2021). Deafness and hearing loss. https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/deafness-and-hearing-loss."},{"key":"10.1016\/j.medj.2025.100696_bib2","doi-asserted-by":"crossref","first-page":"2151","DOI":"10.1056\/NEJMra050700","article-title":"Newborn hearing screening--a silent revolution","volume":"354","author":"Morton","year":"2006","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.medj.2025.100696_bib3","doi-asserted-by":"crossref","first-page":"2195","DOI":"10.1001\/jama.2020.17647","article-title":"Hearing Loss in Children: A Review","volume":"324","author":"Lieu","year":"2020","journal-title":"JAMA"},{"key":"10.1016\/j.medj.2025.100696_bib4","doi-asserted-by":"crossref","first-page":"2151","DOI":"10.1056\/NEJMra050700","article-title":"Newborn hearing screening-a silent revolution","volume":"354","author":"Morton","year":"2006","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.medj.2025.100696_bib5","doi-asserted-by":"crossref","first-page":"1789","DOI":"10.1016\/S0140-6736(18)32279-7","article-title":"Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990\u20132017: a systematic analysis for the Global Burden of Disease Study 2017","volume":"392","author":"James","year":"2018","journal-title":"Lancet"},{"key":"10.1016\/j.medj.2025.100696_bib6","author":"Walls"},{"key":"10.1016\/j.medj.2025.100696_bib7","doi-asserted-by":"crossref","DOI":"10.1016\/j.omtm.2023.101154","article-title":"Preclinical evaluation of the efficacy and safety of AAV1-hOTOF in mice and nonhuman primates","volume":"31","author":"Zhang","year":"2023","journal-title":"Mol. Ther. Methods Clin. Dev."},{"key":"10.1016\/j.medj.2025.100696_bib8","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1007\/s00439-022-02504-2","article-title":"Hearing of Otof-deficient mice restored by trans-splicing of N- and C-terminal otoferlin","volume":"142","author":"Tang","year":"2023","journal-title":"Hum. Genet."},{"key":"10.1016\/j.medj.2025.100696_bib9","doi-asserted-by":"crossref","first-page":"4496","DOI":"10.1073\/pnas.1817537116","article-title":"Dual AAV-mediated gene therapy restores hearing in a DFNB9 mouse model","volume":"116","author":"Akil","year":"2019","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.medj.2025.100696_bib10","doi-asserted-by":"crossref","DOI":"10.15252\/emmm.201809396","article-title":"A dual-AAV approach restores fast exocytosis and partially rescues auditory function in deaf otoferlin knock-out mice","volume":"11","author":"Al-Moyed","year":"2019","journal-title":"EMBO Mol. Med."},{"key":"10.1016\/j.medj.2025.100696_bib11","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1016\/j.ymthe.2023.02.001","article-title":"Advances in gene therapy hold promise for treating hereditary hearing loss","volume":"31","author":"Jiang","year":"2023","journal-title":"Mol. Ther."},{"key":"10.1016\/j.medj.2025.100696_bib12","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/j.addr.2020.05.001","article-title":"Advances in genome editing for genetic hearing loss","volume":"168","author":"Ding","year":"2021","journal-title":"Adv. Drug Deliv. Rev."},{"key":"10.1016\/j.medj.2025.100696_bib13","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1038\/s41434-020-0155-7","article-title":"Recent development of AAV-based gene therapies for inner ear disorders","volume":"27","author":"Lan","year":"2020","journal-title":"Gene Ther."},{"key":"10.1016\/j.medj.2025.100696_bib14","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1038\/s41576-023-00597-7","article-title":"Deafness: from genetic architecture to gene therapy","volume":"24","author":"Petit","year":"2023","journal-title":"Nat. Rev. Genet."},{"key":"10.1016\/j.medj.2025.100696_bib15","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/j.cell.2006.08.040","article-title":"Otoferlin, defective in a human deafness form, is essential for exocytosis at the auditory ribbon synapse","volume":"127","author":"Roux","year":"2006","journal-title":"Cell"},{"key":"10.1016\/j.medj.2025.100696_bib16","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.31013","article-title":"Otoferlin acts as a Ca(2+) sensor for vesicle fusion and vesicle pool replenishment at auditory hair cell ribbon synapses","volume":"6","author":"Michalski","year":"2017","journal-title":"Elife"},{"key":"10.1016\/j.medj.2025.100696_bib17","doi-asserted-by":"crossref","first-page":"3085","DOI":"10.1038\/s41467-023-38621-3","article-title":"Cochlear transcript diversity and its role in auditory functions implied by an otoferlin short isoform","volume":"14","author":"Liu","year":"2023","journal-title":"Nat. Commun."},{"key":"10.1016\/j.medj.2025.100696_bib18","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1038\/7693","article-title":"A mutation in OTOF, encoding otoferlin, a FER-1-like protein, causes DFNB9, a nonsyndromic form of deafness","volume":"21","author":"Yasunaga","year":"1999","journal-title":"Nat. Genet."},{"key":"10.1016\/j.medj.2025.100696_bib19","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1111\/cge.12744","article-title":"High frequency of OTOF mutations in Chinese infants with congenital auditory neuropathy spectrum disorder","volume":"90","author":"Zhang","year":"2016","journal-title":"Clin. Genet."},{"key":"10.1016\/j.medj.2025.100696_bib20","doi-asserted-by":"crossref","first-page":"1429","DOI":"10.1007\/s00439-023-02595-5","article-title":"The natural history, clinical outcomes, and genotype-phenotype relationship of otoferlin-related hearing loss: a systematic, quantitative literature review","volume":"142","author":"Ford","year":"2023","journal-title":"Hum. Genet."},{"key":"10.1016\/j.medj.2025.100696_bib21","doi-asserted-by":"crossref","first-page":"2317","DOI":"10.1016\/S0140-6736(23)02874-X","article-title":"AAV1-hOTOF gene therapy for autosomal recessive deafness 9: a single-arm trial","volume":"403","author":"Lv","year":"2024","journal-title":"Lancet"},{"key":"10.1016\/j.medj.2025.100696_bib22","doi-asserted-by":"crossref","first-page":"1898","DOI":"10.1038\/s41591-024-03023-5","article-title":"Bilateral gene therapy in children with autosomal recessive deafness 9: single-arm trial results","volume":"30","author":"Wang","year":"2024","journal-title":"Nat. Med."},{"key":"10.1016\/j.medj.2025.100696_bib23","doi-asserted-by":"crossref","DOI":"10.1002\/advs.202306788","article-title":"AAV-Mediated Gene Therapy Restores Hearing in Patients with DFNB9 Deafness","volume":"11","author":"Qi","year":"2024","journal-title":"Adv. Sci."},{"key":"10.1016\/j.medj.2025.100696_bib24","doi-asserted-by":"crossref","first-page":"2267","DOI":"10.1016\/S0140-6736(24)00496-3","article-title":"Gene therapy proves successful in treating hereditary deafness","volume":"403","author":"Reisinger","year":"2024","journal-title":"Lancet"},{"key":"10.1016\/j.medj.2025.100696_bib25","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/01.HJ.0001007680.56049.93","article-title":"Gene Therapy Restored Partial Hearing in a Dozen Deaf Children","volume":"77","author":"Zeng","year":"2024","journal-title":"Hear. J."},{"key":"10.1016\/j.medj.2025.100696_bib26","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1007\/s12070-012-0581-y","article-title":"Reliability of Auditory Steady-State Response (ASSR): Comparing Thresholds of Auditory Steady-State Response (ASSR) with Auditory Brainstem Response (ABR) in Children with Severe Hearing Loss","volume":"65","author":"Kandogan","year":"2013","journal-title":"Indian J. Otolaryngol. Head Neck Surg."},{"key":"10.1016\/j.medj.2025.100696_bib27","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1001\/archneur.1979.00500380051005","article-title":"Brain stem auditory evoked responses: studies of waveform variations in 50 normal human subjects","volume":"36","author":"Chiappa","year":"1979","journal-title":"Arch. Neurol."},{"key":"10.1016\/j.medj.2025.100696_bib28","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1016\/j.neures.2012.05.001","article-title":"Normal variations in the morphology of auditory brainstem response (ABR) waveforms: a study in Wistar rats","volume":"73","author":"Alvarado","year":"2012","journal-title":"Neurosci. Res."},{"key":"10.1016\/j.medj.2025.100696_bib29","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1097\/01.AUD.0000130801.96611.6B","article-title":"Determining the upper limits of stimulation for auditory steady-state response measurements","volume":"25","author":"Gorga","year":"2004","journal-title":"Ear Hear."},{"key":"10.1016\/j.medj.2025.100696_bib30","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1080\/1086508X.2004.11079481","article-title":"Otoacoustic emissions","volume":"44","author":"Oostenbrink","year":"2004","journal-title":"Am. J. Electroneurodiagnostic Technol."},{"key":"10.1016\/j.medj.2025.100696_bib31","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1097\/00003446-199004000-00009","article-title":"The clinical utility of distortion-product otoacoustic emissions","volume":"11","author":"Lonsbury-Martin","year":"1990","journal-title":"Ear Hear."},{"key":"10.1016\/j.medj.2025.100696_bib32","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1055\/s-0042-1756160","article-title":"Auditory Evoked Potentials in Communication Disorders: An Overview of Past, Present, and Future","volume":"43","author":"Maggu","year":"2022","journal-title":"Semin. Hear."},{"key":"10.1016\/j.medj.2025.100696_bib33","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1016\/j.clinph.2007.12.004","article-title":"Linear and nonlinear changes in the auditory brainstem response of aging humans","volume":"119","author":"Lavoie","year":"2008","journal-title":"Clin. Neurophysiol."},{"key":"10.1016\/j.medj.2025.100696_bib34","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1097\/01.aud.0000194511.14740.9c","article-title":"Using a combination of click- and tone burst-evoked auditory brain stem response measurements to estimate pure-tone thresholds","volume":"27","author":"Gorga","year":"2006","journal-title":"Ear Hear."},{"key":"10.1016\/j.medj.2025.100696_bib35","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1097\/00003446-199508000-00003","article-title":"Thresholds for auditory brain stem responses to tones in notched noise from infants and young children with normal hearing or sensorineural hearing loss","volume":"16","author":"Stapells","year":"1995","journal-title":"Ear Hear."},{"key":"10.1016\/j.medj.2025.100696_bib36","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1001\/archotol.1974.00780030034006","article-title":"Brain stem auditory evoked responses in human infants and adults","volume":"99","author":"Hecox","year":"1974","journal-title":"Arch. Otolaryngol."},{"key":"10.1016\/j.medj.2025.100696_bib37","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1016\/j.ijporl.2014.01.020","article-title":"Evaluation of waveform, latency and amplitude values of chirp ABR in newborns","volume":"78","author":"Cebulla","year":"2014","journal-title":"Int. J. Pediatr. Otorhinolaryngol."},{"key":"10.1016\/j.medj.2025.100696_bib38","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1097\/01.AUD.0000100203.65990.D4","article-title":"Activity-dependent developmental plasticity of the auditory brain stem in children who use cochlear implants","volume":"24","author":"Gordon","year":"2003","journal-title":"Ear Hear."},{"key":"10.1016\/j.medj.2025.100696_bib39","doi-asserted-by":"crossref","first-page":"1671","DOI":"10.1016\/j.clinph.2007.04.030","article-title":"Auditory brainstem activity and development evoked by apical versus basal cochlear implant electrode stimulation in children","volume":"118","author":"Gordon","year":"2007","journal-title":"Clin. Neurophysiol."},{"key":"10.1016\/j.medj.2025.100696_bib40","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1097\/WNR.0b013e32834fab4b","article-title":"Long-term monaural auditory deprivation and bilateral cochlear implants","volume":"23","author":"Boisvert","year":"2012","journal-title":"Neuroreport"},{"key":"10.1016\/j.medj.2025.100696_bib41","doi-asserted-by":"crossref","DOI":"10.1016\/j.dcn.2019.100689","article-title":"Corrigendum to \"Alterations of structural and functional connectivity in profound sensorineural hearing loss infants within an early sensitive period: A combined DTI and fMRI study\" [Dev. Cogn. Neurosci. 38 (2019) 100654]","volume":"41","author":"Wang","year":"2020","journal-title":"Dev. Cogn. Neurosci."},{"key":"10.1016\/j.medj.2025.100696_bib42","doi-asserted-by":"crossref","first-page":"1323","DOI":"10.1016\/j.clinph.2020.03.012","article-title":"Deficit of long-term memory traces for words in children with cochlear implants","volume":"131","author":"Zhang","year":"2020","journal-title":"Clin. Neurophysiol."},{"key":"10.1016\/j.medj.2025.100696_bib43","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/0013-4694(88)90048-X","article-title":"On the rate of maturation of sensory evoked potentials","volume":"70","author":"Eggermont","year":"1988","journal-title":"Electroencephalogr. Clin. Neurophysiol."},{"key":"10.1016\/j.medj.2025.100696_bib44","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/0378-5955(87)90033-5","article-title":"The maturation of the central auditory conduction in preterm infants until three months post term. II. The auditory brainstem responses (ABRs)","volume":"26","author":"Rotteveel","year":"1987","journal-title":"Hear. Res."},{"key":"10.1016\/j.medj.2025.100696_bib45","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/0378-5955(88)90019-6","article-title":"Maturational time course for the ABR in preterm and full term infants","volume":"33","author":"Eggermont","year":"1988","journal-title":"Hear. Res."},{"key":"10.1016\/j.medj.2025.100696_bib46","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1001\/archotol.130.5.531","article-title":"Auditory steady-state responses for children with severe to profound hearing loss","volume":"130","author":"Swanepoel","year":"2004","journal-title":"Arch. Otolaryngol. Head Neck Surg."},{"key":"10.1016\/j.medj.2025.100696_bib47","doi-asserted-by":"crossref","first-page":"1207","DOI":"10.1097\/AUD.0000000000000580","article-title":"Evaluation of Speed and Accuracy of Next-Generation Auditory Steady State Response and Auditory Brainstem Response Audiometry in Children With Normal Hearing and Hearing Loss","volume":"39","author":"Sininger","year":"2018","journal-title":"Ear Hear."},{"key":"10.1016\/j.medj.2025.100696_bib48","doi-asserted-by":"crossref","first-page":"1129","DOI":"10.1080\/14992027.2022.2124199","article-title":"Do cochlear microphonics evoked by narrow-band chirp stimuli affect the objective detection of auditory steady-state responses?","volume":"62","author":"Cebulla","year":"2023","journal-title":"Int. J. Audiol."},{"key":"10.1016\/j.medj.2025.100696_bib49","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1159\/000259252","article-title":"Estimation of the pure-tone audiogram by the auditory brainstem response: a review","volume":"2","author":"Stapells","year":"1997","journal-title":"Audiol. Neurootol."},{"key":"10.1016\/j.medj.2025.100696_bib50","first-page":"105","article-title":"The Validity of auditory steady-state response as frequency-specific threshold test in infant-toddlers","volume":"10","author":"Park","year":"2006","journal-title":"Korean Journal of Audiology"},{"key":"10.1016\/j.medj.2025.100696_bib51","doi-asserted-by":"crossref","first-page":"1449","DOI":"10.1016\/j.ijporl.2007.05.029","article-title":"Auditory brainstem response in premature and full-term children","volume":"71","author":"Sleifer","year":"2007","journal-title":"Int. J. Pediatr. Otorhinolaryngol."},{"key":"10.1016\/j.medj.2025.100696_bib52","doi-asserted-by":"crossref","first-page":"30","DOI":"10.3766\/jaaa.26.1.4","article-title":"Continued maturation of the click-evoked auditory brainstem response in preschoolers","volume":"26","author":"Spitzer","year":"2015","journal-title":"J. Am. Acad. Audiol."},{"key":"10.1016\/j.medj.2025.100696_bib53","series-title":"Otoacoustic Emissions","author":"Young","year":"2025"},{"key":"10.1016\/j.medj.2025.100696_bib54","doi-asserted-by":"crossref","DOI":"10.1155\/2007\/80904","article-title":"Blockade of cochlear NMDA receptors prevents long-term tinnitus during a brief consolidation window after acoustic trauma","volume":"2007","author":"Guitton","year":"2007","journal-title":"Neural Plast."},{"key":"10.1016\/j.medj.2025.100696_bib55","doi-asserted-by":"crossref","first-page":"12","DOI":"10.3389\/fnsys.2012.00012","article-title":"Tinnitus: pathology of synaptic plasticity at the cellular and system levels","volume":"6","author":"Guitton","year":"2012","journal-title":"Front. Syst. Neurosci."}],"container-title":["Med"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666634025001230?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666634025001230?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T08:59:10Z","timestamp":1778921950000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2666634025001230"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8]]},"references-count":55,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2025,8]]}},"alternative-id":["S2666634025001230"],"URL":"https:\/\/doi.org\/10.1016\/j.medj.2025.100696","relation":{},"ISSN":["2666-6340"],"issn-type":[{"value":"2666-6340","type":"print"}],"subject":[],"published":{"date-parts":[[2025,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Audiological characteristics following gene therapy in patients with autosomal recessive deafness 9","name":"articletitle","label":"Article Title"},{"value":"Med","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.medj.2025.100696","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"100696"}}