{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T08:48:02Z","timestamp":1790930882820,"version":"4.1.0"},"reference-count":100,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T00:00:00Z","timestamp":1104537600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T00:00:00Z","timestamp":1104537600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.fr","em-consulte.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["M\u00e9decine et Maladies Infectieuses"],"published-print":{"date-parts":[[2005,1]]},"DOI":"10.1016\/j.medmal.2004.08.003","type":"journal-article","created":{"date-parts":[[2004,12,14]],"date-time":"2004-12-14T10:22:01Z","timestamp":1103019721000},"page":"6-16","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":45,"title":["La brucellose \u00e0 l\u2019aube du 21e si\u00e8cle"],"prefix":"10.1016","volume":"35","author":[{"given":"M.","family":"Maurin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.medmal.2004.08.003_bib1","first-page":"168","article-title":"Brucellosis","volume":"18","author":"Sarinas","year":"2003","journal-title":"Sem Resp. Infect."},{"key":"10.1016\/j.medmal.2004.08.003_bib2","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1177\/104063879400600408","article-title":"Characteristics of a Brucella species from a bottlenose dolphin (Tursiops truncatus)","volume":"6","author":"Ewalt","year":"1994","journal-title":"J. Vet. Diagn. Investig."},{"key":"10.1016\/j.medmal.2004.08.003_bib3","doi-asserted-by":"crossref","first-page":"1258","DOI":"10.1128\/JCM.38.3.1258-1262.2000","article-title":"Molecular characterization of Brucella strains isolated from marine mammals","volume":"38","author":"Bricker","year":"2000","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.medmal.2004.08.003_bib4","doi-asserted-by":"crossref","first-page":"485","DOI":"10.3201\/eid0904.020576","article-title":"Human neurobrucellosis with intracerebral granuloma caused by a marine mammal Brucella spp","volume":"9","author":"Sohn","year":"2003","journal-title":"Emerg. Infect. Dis."},{"key":"10.1016\/j.medmal.2004.08.003_bib5","doi-asserted-by":"crossref","first-page":"3055","DOI":"10.1016\/S0264-410X(02)00300-6","article-title":"Overview\u00a0: cause and prevention in biowarfare and bioterrorism","volume":"20","author":"Hilleman","year":"2002","journal-title":"Vaccine"},{"key":"10.1016\/j.medmal.2004.08.003_bib6","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1128\/CMR.14.2.364-381.2001","article-title":"Bioterrorism: implications for the clinical microbiologist","volume":"14","author":"Klietmann","year":"2001","journal-title":"Clin. Microbiol. Rev."},{"key":"10.1016\/j.medmal.2004.08.003_bib7","doi-asserted-by":"crossref","first-page":"3569","DOI":"10.1128\/jb.172.7.3569-3576.1990","article-title":"Brucella abortus 16SrRNA and lipid A reveal a phylogenetic relationship with members of the alpha-2 subdivision of the class Proteobacteria","volume":"172","author":"Moreno","year":"1990","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.medmal.2004.08.003_bib8","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1111\/j.1574-6968.1993.tb06014.x","article-title":"Phylogenetic analysis of the family Rhizobiaceae and related bacteria by sequencing of 16S rRNA gene using PCR and DNA sequencer","volume":"107","author":"Yanagi","year":"1993","journal-title":"FEMS Microbiol. Lett."},{"key":"10.1016\/j.medmal.2004.08.003_bib9","first-page":"373","article-title":"The characterisation of Brucella strains isolated from marine mammals Vet","volume":"57","author":"Jahans","year":"1997","journal-title":"Microbiol."},{"key":"10.1016\/j.medmal.2004.08.003_bib10","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1016\/S1286-4579(01)01427-7","article-title":"Classification of Brucella spp. isolated from marine mammals: polymorphism at the omp2 locus","volume":"3","author":"Cloeckaert","year":"2001","journal-title":"Microbes Infect."},{"key":"10.1016\/j.medmal.2004.08.003_bib11","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1016\/S1286-4579(03)00091-1","article-title":"Classification of Brucella strains isolated from marine mammals: infrequent restriction site-PCR and development of specific PCR identification tests","volume":"5","author":"Cloeckaert","year":"2003","journal-title":"Microbes Infect."},{"key":"10.1016\/j.medmal.2004.08.003_bib12","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1099\/00207713-35-3-292","article-title":"Brucella, a monospecific genus as shown by deoxyribonucleic acid hybridization","volume":"35","author":"Verger","year":"1985","journal-title":"Int. J. Syst. Bacteriol."},{"key":"10.1016\/j.medmal.2004.08.003_bib13","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1016\/S0923-2508(00)01145-1","article-title":"Classification of Brucella strain isolated from marine mammals using DNA-DNA hybridization and ribotyping","volume":"151","author":"Verger","year":"2000","journal-title":"Res. Microbiol."},{"key":"10.1016\/j.medmal.2004.08.003_bib14","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1128\/JCM.39.1.235-240.2001","article-title":"Limited genetic diversity of Brucella spp","volume":"39","author":"Gandara","year":"2001","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.medmal.2004.08.003_bib15","series-title":"Manual of Clinical Microbiology","first-page":"625","article-title":"Brucella","author":"Shapiro","year":"1999"},{"key":"10.1016\/j.medmal.2004.08.003_bib16","doi-asserted-by":"crossref","first-page":"3437","DOI":"10.1128\/JCM.37.11.3437-3442.1999","article-title":"Detection of Brucellae in blood cultures","volume":"37","author":"Yagupsky","year":"1999","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.medmal.2004.08.003_bib17","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1086\/421024","article-title":"Prevention of laboratory-acquired brucellosis","volume":"38","author":"Robichaud","year":"2004","journal-title":"Clin. Infect. Dis."},{"key":"10.1016\/j.medmal.2004.08.003_bib18","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1016\/0923-2508(96)80563-8","article-title":"Heterogeneity of Brucella abortus lipopolysaccharides","volume":"146","author":"Freer","year":"1995","journal-title":"Res. Microbiol."},{"key":"10.1016\/j.medmal.2004.08.003_bib19","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1128\/CMR.16.1.65-78.2003","article-title":"Molecular host-pathogen interaction in brucellosis: current understanding and future approaches to vaccine development for mice and humans","volume":"16","author":"Ko","year":"2003","journal-title":"Clin. Microbiol. Rev."},{"key":"10.1016\/j.medmal.2004.08.003_bib20","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1016\/S0369-8114(02)00313-9","article-title":"Brucella \u00e0 l\u2019aube du troisi\u00e8me mill\u00e9naire\u00a0: organisation du g\u00e9nome et pouvoir pathog\u00e8ne","volume":"50","author":"Michaux-Charachon","year":"2002","journal-title":"Pathol. Biol."},{"key":"10.1016\/j.medmal.2004.08.003_bib21","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1128\/CDLI.6.4.627-629.1999","article-title":"Brucella outer membrane lipoproteins share antigenic determinants with bacteria of the family Rhizobiaceae","volume":"6","author":"Cloackaert","year":"1999","journal-title":"Clin. Diagn. Lab. Immunol."},{"key":"10.1016\/j.medmal.2004.08.003_bib22","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1073\/pnas.221575398","article-title":"The genome sequence of the facultative intracellular pathogen Brucella melitensis","volume":"99","author":"DelVecchio","year":"2002","journal-title":"Proc. Natl. Acad. Sci. U.S.A"},{"key":"10.1016\/j.medmal.2004.08.003_bib23","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1128\/jb.175.3.701-705.1993","article-title":"Presence of two independant chromosomes in the Brucella melitensis genome","volume":"175","author":"Michaux","year":"1993","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.medmal.2004.08.003_bib24","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1046\/j.1365-2958.1998.00661.x","article-title":"Diff\u00e9rences in chromosome number and genome rearrangements in the genus Brucella","volume":"27","author":"Jumas-Bilak","year":"1998","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.medmal.2004.08.003_bib25","doi-asserted-by":"crossref","first-page":"13148","DOI":"10.1073\/pnas.192319099","article-title":"The Brucella suis genome reveals fundamental similarities between animal and plant pathogens and symbionts","volume":"99","author":"Paulsen","year":"2002","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.medmal.2004.08.003_bib26","doi-asserted-by":"crossref","first-page":"213","DOI":"10.3201\/eid0302.970219","article-title":"Brucellosis\u00a0: an overview","volume":"3","author":"Corbel","year":"1997","journal-title":"Emerg. Infect. Dis."},{"key":"10.1016\/j.medmal.2004.08.003_bib27","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1093\/clinids\/21.2.283","article-title":"An overview of human brucellosis","volume":"21","author":"Young","year":"1995","journal-title":"Clin. Infect. Dis."},{"key":"10.1016\/j.medmal.2004.08.003_bib28","doi-asserted-by":"crossref","unstructured":"Garin-Bastuji B, Delcueillerie F. Les brucelloses humaine et animale en France en l\u2019an 2000. Situation \u00e9pid\u00e9miologique \u2013 Programmes de contr\u00f4le et d\u2019\u00e9radication. Med Mal Infect 2001; 31 suppl 2\u00a0: 202-216.","DOI":"10.1016\/S0399-077X(01)80061-5"},{"key":"10.1016\/j.medmal.2004.08.003_bib29","unstructured":"Durr U, Valenciano M, Vaillant V. La brucellose humaine en France de 1998 \u00e0 2000. Surveillance Nationale des maladies infectieuses. Institut de Veille Sanitaire. Rapport 1998-2000. 2003."},{"key":"10.1016\/j.medmal.2004.08.003_bib30","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/S0378-1135(02)00217-1","article-title":"Brucellosis in the European Union and Norway at the turn of the twenty-first century","volume":"90","author":"Godfroid","year":"2002","journal-title":"Vet. Microbiol."},{"key":"10.1016\/j.medmal.2004.08.003_bib31","doi-asserted-by":"crossref","first-page":"277","DOI":"10.20506\/rst.21.2.1333","article-title":"Brucellosis in wildlife","volume":"21","author":"Godfroid","year":"2002","journal-title":"Rev. Sci. Tech. Off Epiz"},{"key":"10.1016\/j.medmal.2004.08.003_bib32","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/0140-6736(91)93332-4","article-title":"Person-to-person transmission of Brucella melitensis","volume":"1","author":"Ruben","year":"1991","journal-title":"Lancet"},{"key":"10.1016\/j.medmal.2004.08.003_bib33","doi-asserted-by":"crossref","first-page":"1325","DOI":"10.1001\/jama.1957.62980120003007a","article-title":"Brucellosis in man, resulting from Brucella abortus (strain 19) vaccine","volume":"164","author":"Sadusk","year":"1957","journal-title":"JAMA"},{"key":"10.1016\/j.medmal.2004.08.003_bib34","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1093\/clinids\/5.5.821","article-title":"Human brucellosis","volume":"5","author":"Young","year":"1983","journal-title":"Rev. Infect. Dis."},{"key":"10.1016\/j.medmal.2004.08.003_bib35","first-page":"172","article-title":"Human exposure to Brucella abortus strain RB51, Kansas, 1997","volume":"47","year":"1998","journal-title":"MMWR"},{"key":"10.1016\/j.medmal.2004.08.003_bib36","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1128\/IAI.68.1.342-351.2000","article-title":"In vitro Brucella suis infection prevents the programmed cell death of human monocytic cells","volume":"68","author":"Gross","year":"2000","journal-title":"Infect. Immun."},{"key":"10.1016\/j.medmal.2004.08.003_bib37","doi-asserted-by":"crossref","first-page":"1210","DOI":"10.1046\/j.1365-2958.1999.01569.x","article-title":"A homologue of the Agrobacterium tumefaciens VirB and Bordetella pertussis Ptl type IV secretion systems is essential for intracellular survival of Brucella suis","volume":"33","author":"O\u2019Callaghan","year":"1999","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.medmal.2004.08.003_bib38","doi-asserted-by":"crossref","first-page":"4102","DOI":"10.1128\/IAI.68.7.4102-4107.2000","article-title":"Identification of genes required for chonic persistence of Brucella abortus in mice","volume":"68","author":"Hong","year":"2000","journal-title":"Infect. Immun."},{"key":"10.1016\/j.medmal.2004.08.003_bib39","doi-asserted-by":"crossref","first-page":"1544","DOI":"10.1073\/pnas.032514299","article-title":"The Brucella suis virB operon is induced intracellularly in macrophages","volume":"99","author":"Boschiroli","year":"2001","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.medmal.2004.08.003_bib40","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1097\/00005792-199607000-00003","article-title":"Complications associated with Brucella melitensis infection: a study of 530 cases","volume":"75","author":"Colmenero","year":"1996","journal-title":"Medicine"},{"key":"10.1016\/j.medmal.2004.08.003_bib41","doi-asserted-by":"crossref","first-page":"1440","DOI":"10.1086\/313524","article-title":"Brucellar spondylitis: review of 35 cases and literature survey","volume":"29","author":"Solera","year":"1999","journal-title":"Clin. Infect. Dis."},{"key":"10.1016\/j.medmal.2004.08.003_bib42","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1007\/s10096-003-1026-z","article-title":"Brucella endocarditis: clinical , diagnostic, and therapeutic approach","volume":"22","author":"Reguera","year":"2003","journal-title":"Eur. J. Microbiol. Infect. Dis."},{"key":"10.1016\/j.medmal.2004.08.003_bib43","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/S0163-4453(98)94279-7","article-title":"Central nervous system brucellosis: presentation, diagnosis and treatment","volume":"36","author":"Akdeniz","year":"1998","journal-title":"J. Infect."},{"key":"10.1016\/j.medmal.2004.08.003_bib44","doi-asserted-by":"crossref","first-page":"1024","DOI":"10.1086\/319608","article-title":"Current understanding and management of chronic hepatosplenic suppurative brucellosis","volume":"32","author":"Ariza","year":"2001","journal-title":"Clin. Infect. Dis."},{"key":"10.1016\/j.medmal.2004.08.003_bib45","doi-asserted-by":"crossref","first-page":"1172","DOI":"10.1086\/319758","article-title":"Brucellosis in pregnant women","volume":"32","author":"Khan","year":"2001","journal-title":"Clin. Infect. Dis."},{"key":"10.1016\/j.medmal.2004.08.003_bib46","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1007\/BF01709454","article-title":"Brucellosis in patients infected with the human immunodeficiency virus","volume":"17","author":"Moreno","year":"1998","journal-title":"Eur. J. Clin. Micrbiol. Infect. Dis. J."},{"key":"10.1016\/j.medmal.2004.08.003_bib47","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1128\/jcm.30.3.604-607.1992","article-title":"Differentiation between active and inactive human brucellosis by measuring atiprotein humoral immune responses","volume":"30","author":"Goldbaum","year":"1992","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.medmal.2004.08.003_bib48","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1128\/CDLI.6.5.756-759.1999","article-title":"Detection of antibodies to Brucella cytoplasmic proteins in the cerebrospinal fluid of patients with neurobrucellosis","volume":"6","author":"Baldi","year":"1999","journal-title":"Clin. Diagn. Labo. Immunol."},{"key":"10.1016\/j.medmal.2004.08.003_bib49","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1128\/cdli.4.6.748-752.1997","article-title":"Afipia clevelandensis antibodies and cross-reactivity with Brucella spp. and Yersinia enterocolitica O:9","volume":"4","author":"Drancourt","year":"1997","journal-title":"Clin. Diagn. Lab. Immunol."},{"key":"10.1016\/j.medmal.2004.08.003_bib50","doi-asserted-by":"crossref","first-page":"1570","DOI":"10.1128\/jcm.28.7.1570-1574.1990","article-title":"Differentiation of serological responses to Yersinia enterocolitica serotype O9 and Brucella species by immunoblot or enzyme-linked immunosorbent assay using whole bacteria and Yersinia outer memebrane proteins","volume":"28","author":"Schoerner","year":"1990","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.medmal.2004.08.003_bib51","first-page":"710","article-title":"Enzyme-linked immunosorbent assay to differentiate the antibody responses of animals infected with Brucella species from those of animals infected with Yersinia enterocolitica O9","volume":"10","author":"Erdenebaatar","year":"2003","journal-title":"Clin. Diagn. Lab. Immunol."},{"key":"10.1016\/j.medmal.2004.08.003_bib52","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1007\/BF03401711","article-title":"Detection and differentiation of the six Brucella species by polymerase chain reaction","volume":"3","author":"Sifuentes-Rincon","year":"1997","journal-title":"Mol. Med."},{"key":"10.1016\/j.medmal.2004.08.003_bib53","doi-asserted-by":"crossref","first-page":"2927","DOI":"10.1128\/jcm.35.11.2927-2930.1997","article-title":"Rapid diagnosis of human brucellosis by peripheral-blood PCR assay","volume":"35","author":"Queipo-Ortuno","year":"1997","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.medmal.2004.08.003_bib54","doi-asserted-by":"crossref","first-page":"1661","DOI":"10.1128\/JCM.39.4.1661-1664.2001","article-title":"Serum is the peferred clinical specimen for diagnosis of human brucellosis by PCR","volume":"39","author":"Zerva","year":"2001","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.medmal.2004.08.003_bib55","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1007\/PL00011242","article-title":"Specificity of a polymerase chain reaction assay of a target sequence on the 31-kilodalton Brucella antigen DNA used to diagnose human brucellosis","volume":"20","author":"Casanas","year":"2001","journal-title":"Eur. J. Clin. Microbiol. Infect. Dis."},{"key":"10.1016\/j.medmal.2004.08.003_bib56","doi-asserted-by":"crossref","first-page":"3743","DOI":"10.1128\/JCM.39.10.3743-3746.2001","article-title":"Diagnostic yield of a PCR assay in focal complications of brucellosis","volume":"39","author":"Morata","year":"2001","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.medmal.2004.08.003_bib57","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1128\/jcm.34.2.477-478.1996","article-title":"Rapid laboratory confirmation of human brucellosis by PCR analysis of a target sequence on the 31-kilodalton Brucella antigen DNA","volume":"34","author":"Matar","year":"1996","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.medmal.2004.08.003_bib58","doi-asserted-by":"crossref","first-page":"2443","DOI":"10.1128\/JCM.36.9.2443-2446.1998","article-title":"Strategy for optimizing DNA amplification in a peripheral blood PCR assay used for diagnosis f human brucellosis","volume":"36","author":"Morata","year":"1998","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.medmal.2004.08.003_bib59","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1128\/JCM.41.1.144-148.2003","article-title":"Development and evaluation of a PCR-enzyme linked immunosorbent assay for diagnosis of human brucellosis","volume":"41","author":"Morata","year":"2003","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.medmal.2004.08.003_bib60","doi-asserted-by":"crossref","first-page":"3743","DOI":"10.1128\/JCM.39.10.3743-3746.2001","article-title":"Diagnostic yield of a PCR assay in focal complications of brucellosis","volume":"39","author":"Morata","year":"2001","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.medmal.2004.08.003_bib61","doi-asserted-by":"crossref","first-page":"4753","DOI":"10.1128\/AEM.69.8.4753-4759.2003","article-title":"Real-time PCR detection of Brucella abortus: a comparative study of SYBR green I, 5\u2019-exonuclease, and hybridization probe assays","volume":"69","author":"Newby","year":"2003","journal-title":"Applied Envir. Microbiol."},{"key":"10.1016\/j.medmal.2004.08.003_bib62","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1006\/mcpr.2000.0338","article-title":"Real-time detection of Brucella abortus, Brucella melitensis and Brucella suis","volume":"15","author":"Redkar","year":"2001","journal-title":"Mol. Cell. Probes."},{"key":"10.1016\/j.medmal.2004.08.003_bib63","doi-asserted-by":"crossref","first-page":"2660","DOI":"10.1128\/jcm.32.11.2660-2666.1994","article-title":"Differentiation of Brucella abortus bv. 1, 2, and 4, Brucella melitensis, Brucella ovis, and Brucella suis bv. 1 by PCR","volume":"32","author":"Bricker","year":"1994","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.medmal.2004.08.003_bib64","doi-asserted-by":"crossref","first-page":"2261","DOI":"10.1128\/JCM.42.5.2261-2263.2004","article-title":"Validated 5\u2019 nuclease PCR assay for rapid identification of the genus Brucella","volume":"42","author":"Bogdanovich","year":"2004","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.medmal.2004.08.003_bib65","doi-asserted-by":"crossref","first-page":"4603","DOI":"10.1128\/jb.170.10.4603-4607.1988","article-title":"DNA polymorphism in strains of the genus Brucella","volume":"170","author":"Allardet-Servent","year":"1988","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.medmal.2004.08.003_bib66","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1186\/1471-2180-3-15","article-title":"Brucella \u00ab\u00a0HOOF prints\u00a0\u00bb\u00a0: strain typing by multi-locus analysis of variable number tandem repeats (VNTR)","volume":"3","author":"Bricker","year":"2003","journal-title":"BMC Microbiology"},{"key":"10.1016\/j.medmal.2004.08.003_bib67","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1128\/CDLI.7.5.835-839.2000","article-title":"An IS711 element downstream of the bp26 gene os a specific marker of Brucella spp. isolated from marine mammals","volume":"7","author":"Cloeckaert","year":"2000","journal-title":"Clin. Diagn. Lab. Immunol."},{"key":"10.1016\/j.medmal.2004.08.003_bib68","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.1093\/clinids\/12.6.1060","article-title":"Modern chemotherapy for brucellosis in humans","volume":"12","author":"Hall","year":"1990","journal-title":"Rev. Infect. Dis."},{"key":"10.1016\/j.medmal.2004.08.003_bib69","doi-asserted-by":"crossref","first-page":"1925","DOI":"10.1128\/AAC.35.9.1925","article-title":"In vitro susceptibility of Brucella melitensis to antibiotics","volume":"35","author":"Rubinstein","year":"1991","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.medmal.2004.08.003_bib70","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1093\/jac\/17.4.459","article-title":"In vitro activity of ciprofloxacin, ceftriaxone, and five other antimicrobial agents against 95 strains of Brucella melitensis","volume":"17","author":"Bosch","year":"1986","journal-title":"J. Antimicrob. Chemother."},{"key":"10.1016\/j.medmal.2004.08.003_bib71","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1128\/AAC.21.3.501","article-title":"In vitro activity of N-formimidoyl thienamycin against 98 clinical isolates of Brucella melitensis compared with those of cefoxitine, rifampin, tetracycline, and co-trimoxazole","volume":"21","author":"Gutierrez Altes","year":"1982","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.medmal.2004.08.003_bib72","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1007\/BF02098096","article-title":"In vitro activity of azithromycin and tetracycline against 358 clinical isolates of Brucella melitensis","volume":"11","author":"Landinez","year":"1992","journal-title":"Eur. J. Clin. Microbiol. Infect. Dis."},{"key":"10.1016\/j.medmal.2004.08.003_bib73","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1159\/000239353","article-title":"Antibacterial activity of azithromycin against Brucella melitensis","volume":"41","author":"Qadri","year":"1995","journal-title":"Chemotherapy"},{"key":"10.1016\/j.medmal.2004.08.003_bib74","doi-asserted-by":"crossref","unstructured":"Trujillano-Martin I, Garcia-Sanchez E, Montes Martinez I, et al. In vitro activities of six new fluoroquinolones against Brucella melitensis. Antimicob. Agents Chemother. 1999; 43\u00a0: 194\u2013195.","DOI":"10.1128\/AAC.43.1.194"},{"key":"10.1016\/j.medmal.2004.08.003_bib75","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1093\/jac\/18.5.648","article-title":"Rifampicin resistance in a strain of Brucella melitensis after treatment with doxycycline and rifampin","volume":"18","author":"De Rautlin de la Roy","year":"1986","journal-title":"J. Antimicrob. Chemother."},{"key":"10.1016\/j.medmal.2004.08.003_bib76","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1093\/infdis\/152.3.529","article-title":"Treatment of Brucella canis and Brucella abortus in vitro and in vivo by stable plurilamelar vesicle-encapsulated aminoglycosides","volume":"152","author":"Fountain","year":"1985","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.medmal.2004.08.003_bib77","first-page":"189","article-title":"Intracellular killing of Brucella melitensis within mouse peritoneal macrophages: influence of treatment with rifampin. An ultrastructural study","volume":"9","author":"Filice","year":"1986","journal-title":"Microbiologica"},{"key":"10.1016\/j.medmal.2004.08.003_bib78","doi-asserted-by":"crossref","first-page":"1298","DOI":"10.1128\/AAC.43.5.1298","article-title":"In vitro activities of antibiotics alone and in combination against Brucella melitensis at neutral and acidic pHs","volume":"43","author":"Akova","year":"1999","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.medmal.2004.08.003_bib79","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1128\/AAC.36.5.973","article-title":"Therapy of experimental murine brucellosis with streptomycin, co-trimoxazole, ciprofloxacin, ofloxacin, pefloxacin, doxycycline, and rifampin","volume":"36","author":"Shasha","year":"1992","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.medmal.2004.08.003_bib80","series-title":"Antimicrobial therapy and vaccines","first-page":"121","article-title":"Brucella species (brucellosis)","author":"Young","year":"2002"},{"key":"10.1016\/j.medmal.2004.08.003_bib81","doi-asserted-by":"crossref","first-page":"245","DOI":"10.2165\/00003495-199753020-00005","article-title":"Recognition and optimum treatment of brucellosis","volume":"53","author":"Solera","year":"1997","journal-title":"Drugs"},{"key":"10.1016\/j.medmal.2004.08.003_bib82","first-page":"101","article-title":"Le traitement des brucelloses","volume":"2","author":"Rolain","year":"2000","journal-title":"Antibiotiques."},{"key":"10.1016\/j.medmal.2004.08.003_bib83","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1093\/clinids\/14.2.506","article-title":"Failure of ceftriaxone in the treatment of acute brucellosis","volume":"14","author":"Lang","year":"1992","journal-title":"Clin. Infect. Dis."},{"key":"10.1016\/j.medmal.2004.08.003_bib84","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1093\/jac\/29.4.357","article-title":"Quinolones for the treatment of brucellosis","volume":"29","author":"Lang","year":"1992","journal-title":"J. Antimicrob. Chemother."},{"key":"10.1016\/j.medmal.2004.08.003_bib85","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1093\/jac\/23.3.433","article-title":"Comparison of three different regimens in the treatment of acute brucellosis: a multinational study","volume":"23","author":"Acocella","year":"1989","journal-title":"J. Antimicrob. Chemother."},{"key":"10.1016\/j.medmal.2004.08.003_bib86","doi-asserted-by":"crossref","first-page":"25","DOI":"10.7326\/0003-4819-117-1-25","article-title":"Treatment of human brucellosis with doxycycline plus rifampin or doxycycline plus streptomycin","volume":"117","author":"Ariza","year":"1992","journal-title":"Ann. Intern. Med."},{"key":"10.1016\/j.medmal.2004.08.003_bib87","unstructured":"World Health Organization Technical Report Series N\u00b0. 289, Joint FAO\/WHO Expert Committee on Brucellosis, 4th Report, Geneva, 1965."},{"key":"10.1016\/j.medmal.2004.08.003_bib88","unstructured":"World Health Organization Technical Report Series N\u00b0. 740, Joint FAO\/WHO Expert Committee on Brucellosis, 6th Report, Geneva, 1986."},{"key":"10.1016\/j.medmal.2004.08.003_bib89","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1159\/000238662","article-title":"Comparative trial of doxycycline plus streptomycin versus doxycycline plus rifampin for the therapy of human brucellosis","volume":"35","author":"Colmenero Castillo","year":"1989","journal-title":"Chemother."},{"key":"10.1016\/j.medmal.2004.08.003_bib90","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1093\/clind\/16.5.671","article-title":"Open, randomized therapeutic trial of six antimicrobial regimens in the treatment of human brucellosis","volume":"16","author":"Montejo","year":"1993","journal-title":"Clin. Infect. Dis."},{"key":"10.1016\/j.medmal.2004.08.003_bib91","doi-asserted-by":"crossref","first-page":"2061","DOI":"10.1128\/AAC.39.9.2061","article-title":"Doxycycline-rifampin versus doxycycline-streptomycin in treatment of human brucellosis due to Brucella melitensis","volume":"39","author":"Solera","year":"1995","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.medmal.2004.08.003_bib92","first-page":"75","article-title":"A multicenter therapeutic study of 1100 children with brucellosis","volume":"8","author":"Lubani","year":"1989","journal-title":"Pediatr. Infect. Dis."},{"key":"10.1016\/j.medmal.2004.08.003_bib93","doi-asserted-by":"crossref","first-page":"1831","DOI":"10.1128\/AAC.37.9.1831","article-title":"Quinolones in treatment of human brucellosis: comparative trial of ofloxacine-rifampin versus doxycycline-rifampin","volume":"37","author":"Akova","year":"1993","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.medmal.2004.08.003_bib94","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1007\/s100960050344","article-title":"Ciprofloxacin and rifampin versus doxycycline and rifampin in the treatment of brucellosis","volume":"18","author":"Agalar","year":"1999","journal-title":"Eur. J. Clin. Microbiol. Infect. Dis."},{"key":"10.1016\/j.medmal.2004.08.003_bib95","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1097\/00006454-199002000-00002","article-title":"Childhood brucellosis: a study of 102 cases","volume":"9","author":"Al-Eissa","year":"1990","journal-title":"Pediatr. Infect. Dis. J."},{"key":"10.1016\/j.medmal.2004.08.003_bib96","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1097\/00006454-199305000-00005","article-title":"Treatment of childhood brucellosis: results of a prospective trial on 113 children","volume":"12","author":"Khuri-Bulos","year":"1993","journal-title":"Pediatr. Infect. Dis. J."},{"key":"10.1016\/j.medmal.2004.08.003_bib97","doi-asserted-by":"crossref","first-page":"740","DOI":"10.1093\/clinids\/12.5.740","article-title":"Brucella endocarditis: the role of combined medical and surgical treatment","volume":"12","author":"Jacobs","year":"1990","journal-title":"Rev. Infect. Dis."},{"key":"10.1016\/j.medmal.2004.08.003_bib98","first-page":"617","article-title":"Medical care following accidental injection of Brucella abortus, strain 19, in man","volume":"143","author":"McCullough","year":"1963","journal-title":"J. Am. Vet. Med. Assoc."},{"key":"10.1016\/j.medmal.2004.08.003_bib99","doi-asserted-by":"crossref","first-page":"1162","DOI":"10.1001\/jama.1953.02940300020006","article-title":"Human brucellosis caused by Brucella abortus, strain 19","volume":"153","author":"Spink","year":"1953","journal-title":"JAMA"},{"key":"10.1016\/j.medmal.2004.08.003_bib100","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1093\/oxfordjournals.aje.a120624","article-title":"Immunization against Brucella infection. Effects of graded doses of viable attenuated Brucella melitensis in humans","volume":"84","author":"Pappagianis","year":"1966","journal-title":"Am. J. Epidemiol."}],"container-title":["M\u00e9decine et Maladies Infectieuses"],"original-title":[],"language":"fr","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0399077X04002574?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0399077X04002574?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T00:49:38Z","timestamp":1759970978000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0399077X04002574"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,1]]},"references-count":100,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2005,1]]}},"alternative-id":["S0399077X04002574"],"URL":"https:\/\/doi.org\/10.1016\/j.medmal.2004.08.003","relation":{},"ISSN":["0399-077X"],"issn-type":[{"value":"0399-077X","type":"print"}],"subject":[],"published":{"date-parts":[[2005,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"La brucellose \u00e0 l\u2019aube du 21e si\u00e8cle","name":"articletitle","label":"Article Title"},{"value":"M\u00e9decine et Maladies Infectieuses","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.medmal.2004.08.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2004 Elsevier SAS. All rights reserved.","name":"copyright","label":"Copyright"}]}}