{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T02:00:38Z","timestamp":1791252038928,"version":"4.1.0"},"reference-count":25,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2006,4,1]],"date-time":"2006-04-01T00:00:00Z","timestamp":1143849600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2006,4,1]],"date-time":"2006-04-01T00:00:00Z","timestamp":1143849600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.fr","em-consulte.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["M\u00e9decine et Maladies Infectieuses"],"published-print":{"date-parts":[[2006,4]]},"DOI":"10.1016\/j.medmal.2005.10.010","type":"journal-article","created":{"date-parts":[[2006,2,4]],"date-time":"2006-02-04T10:52:58Z","timestamp":1139050378000},"page":"196-200","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"title":["Multiplication intra-amibienne de\u00a0Legionella\u00a0pneumophila et\u00a0r\u00f4le potentiel des\u00a0amibes dans\u00a0la\u00a0transmission de\u00a0la\u00a0l\u00e9gionellose"],"prefix":"10.1016","volume":"36","author":[{"given":"C.","family":"Philippe","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.F.","family":"Blech","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Hartemann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.medmal.2005.10.010_bib1","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1128\/CMR.15.3.506-526.2002","article-title":"Legionella and legionnaire\u2019s disease: 25\u00a0years of investigation","volume":"15","author":"Fields","year":"2002","journal-title":"Clin. Microbiol. Rev."},{"issue":"2","key":"10.1016\/j.medmal.2005.10.010_bib2","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1128\/CMR.16.2.273-307.2003","article-title":"Acanthamoeba spp as agents of disease in humans","volume":"1","author":"Marciano-Cabral","year":"2003","journal-title":"Clin. Microbiol. Rev."},{"issue":"2","key":"10.1016\/j.medmal.2005.10.010_bib3","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1128\/CMR.17.2.413-433.2004","article-title":"Micro-organisms resistant to free-living amoebae","volume":"17","author":"Greub","year":"2002","journal-title":"Clin. Microbiol. Rev."},{"key":"10.1016\/j.medmal.2005.10.010_bib4","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.1136\/jcp.33.12.1179","article-title":"Preliminary report on the pathogenicity of Legionella pneumophila for freshwater and soil amoeba","volume":"33","author":"Rowbotham","year":"1980","journal-title":"J. Clin. Pathol."},{"issue":"1","key":"10.1016\/j.medmal.2005.10.010_bib5","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1128\/iai.45.1.18-24.1984","article-title":"Intracellular growth of Legionella pneumophila within Acanthamoeba castellanii Neff","volume":"45","author":"Holden","year":"1984","journal-title":"Infect. Immun."},{"issue":"7","key":"10.1016\/j.medmal.2005.10.010_bib6","doi-asserted-by":"crossref","first-page":"1950","DOI":"10.1128\/aem.57.7.1950-1955.1991","article-title":"Multiplication of Legionella spp in tap water containing Hartmannella vermiformis","volume":"57","author":"Wadowsky","year":"1991","journal-title":"Appl. Environ. Microbiol."},{"issue":"6","key":"10.1016\/j.medmal.2005.10.010_bib7","doi-asserted-by":"crossref","first-page":"2022","DOI":"10.1128\/aem.62.6.2022-2028.1996","article-title":"The phagosome containing Legionella pneumophila within the protozoan Hartmannella vermiformis is surrounded by the rough endoplasmic reticulum","volume":"62","author":"Abu Kwaik","year":"1996","journal-title":"Appl. Environ. Microbiol."},{"key":"10.1016\/j.medmal.2005.10.010_bib8","doi-asserted-by":"crossref","first-page":"3254","DOI":"10.1128\/iai.62.8.3254-3261.1994","article-title":"Growth of Legionella pneumophila in Acanthamoeba castellanii enhances invasion","volume":"62","author":"Cirillo","year":"1994","journal-title":"Infect. Immun."},{"issue":"8","key":"10.1016\/j.medmal.2005.10.010_bib9","doi-asserted-by":"crossref","first-page":"2420","DOI":"10.1128\/aem.58.8.2420-2425.1992","article-title":"Relationship between Legionella pneumophila and Acanthamoeba polyphaga: physiological status and susceptibility to chemical inactivation","volume":"58","author":"Barker","year":"1992","journal-title":"Appl. Environ. Microbiol."},{"issue":"9","key":"10.1016\/j.medmal.2005.10.010_bib10","doi-asserted-by":"crossref","first-page":"3127","DOI":"10.1128\/AEM.64.9.3127-3133.1998","article-title":"Invasion of protozoa by Legionella pneumophila and its role in bacterial ecology and pathogenesis","volume":"64","author":"Abu Kwaik","year":"1998","journal-title":"Appl. Environ. Microbiol."},{"issue":"2","key":"10.1016\/j.medmal.2005.10.010_bib11","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1128\/aem.51.2.422-424.1986","article-title":"Isolation of protozoa from water associated with a legionellosis outbreak and demonstration of intracellular multiplication of Legionella pneumophila","volume":"51","author":"Barbaree","year":"1986","journal-title":"Appl. Environ. Microbiol."},{"issue":"21","key":"10.1016\/j.medmal.2005.10.010_bib12","doi-asserted-by":"crossref","first-page":"2924","DOI":"10.1001\/jama.1990.03440210074036","article-title":"Association of shower use with Legionaire\u2019s disease. Possible role of amoebae","volume":"263","author":"Breiman","year":"1990","journal-title":"JAMA"},{"issue":"1","key":"10.1016\/j.medmal.2005.10.010_bib13","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/S0195-6701(97)90068-2","article-title":"Colonization of transplant unit water supplies with legionella and precautions required to reduce the risk of legionellosis","volume":"37","author":"Patterson","year":"1997","journal-title":"J. Hosp. Infect."},{"issue":"5","key":"10.1016\/j.medmal.2005.10.010_bib14","doi-asserted-by":"crossref","first-page":"1822","DOI":"10.1128\/AEM.64.5.1822-1824.1998","article-title":"Comparison of free-living amobae in hot water systems of hospitals with isolates from moist sanitary areas by identifying genera and determining temperature tolerance","volume":"64","author":"Rohr","year":"1998","journal-title":"Appl. Environ. Microbiol."},{"issue":"6","key":"10.1016\/j.medmal.2005.10.010_bib15","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1016\/0923-2508(91)90081-K","article-title":"The intracellular multiplication of Legionella pneumophila in protozoa from hospital plumbing systems","volume":"142","author":"Nahapetian","year":"1991","journal-title":"Res. Microbiol. Paris"},{"key":"10.1016\/j.medmal.2005.10.010_bib16","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/S0065-2164(08)70222-3","article-title":"Contact lenses, disinfectants and Acanthamoeba keratitis","volume":"43","author":"Ahearn","year":"1997","journal-title":"Adv. Appl. Microbiol."},{"issue":"5","key":"10.1016\/j.medmal.2005.10.010_bib17","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1111\/j.1365-2672.1990.tb02904.x","article-title":"Survival of Legionella pneumophila within cysts of Acanthamoeba polyphaga following chlorine exposure","volume":"68","author":"Kilvington","year":"1990","journal-title":"J. Appl. Bacteriol."},{"key":"10.1016\/j.medmal.2005.10.010_bib18","doi-asserted-by":"crossref","first-page":"3023","DOI":"10.1128\/aem.54.12.3023-3033.1988","article-title":"Survival of coliforms and bacterial pathogens within protozoa during chlorination","volume":"54","author":"King","year":"1988","journal-title":"Appl. Environ. Microbiol."},{"issue":"1","key":"10.1016\/j.medmal.2005.10.010_bib19","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1078\/S1438-4639(04)70013-9","article-title":"Impact of silver and copper on the survival of amoebae and ciliated protozoa in vitro","volume":"203","author":"Rohr","year":"2000","journal-title":"Int. J. Environ. Health"},{"issue":"12","key":"10.1016\/j.medmal.2005.10.010_bib20","doi-asserted-by":"crossref","first-page":"5330","DOI":"10.1128\/iai.65.12.5330-5333.1997","article-title":"The role of Legionella pneumophila-infected Hartmannella vermiformis as an infectious particle in a murine model of Legionnaire\u2019s disease","volume":"65","author":"Brieland","year":"1997","journal-title":"Infect. Immun."},{"issue":"1","key":"10.1016\/j.medmal.2005.10.010_bib21","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1128\/AEM.64.1.279-286.1998","article-title":"Production of respirable vesicles containing live Legionella pneumophila cells by two Acanthamoeba spp","volume":"64","author":"Berk","year":"1998","journal-title":"Appl. Environ. Microbiol."},{"key":"10.1016\/j.medmal.2005.10.010_bib22","doi-asserted-by":"crossref","first-page":"1253","DOI":"10.1099\/00221287-140-6-1253","article-title":"Trojan horses of the microbial world: protozoa and the survival bacterial pathogens in the environment","volume":"140","author":"Barker","year":"1994","journal-title":"Microbiol."},{"issue":"4","key":"10.1016\/j.medmal.2005.10.010_bib23","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1080\/00365549950163833","article-title":"Free-living amoeba protecting Legionella in water: the tip of an iceberg?","volume":"31","author":"Winiecka-Krusnell","year":"1999","journal-title":"Scand. J. Infect. Dis."},{"key":"10.1016\/j.medmal.2005.10.010_bib24","doi-asserted-by":"crossref","first-page":"2449","DOI":"10.1128\/iai.64.7.2449-2456.1996","article-title":"Coinoculation with Hartmannella vermiformis enhances replicative Legionella pneumophila lung infection in a murine model of human Legionnaire\u2019s disease","volume":"64","author":"Brieland","year":"1996","journal-title":"Infect. Immun."},{"issue":"11","key":"10.1016\/j.medmal.2005.10.010_bib25","doi-asserted-by":"crossref","first-page":"4892","DOI":"10.1128\/iai.65.11.4892-4896.1997","article-title":"Intrapulmonary Hartmannella vermiformis: a potential niche for Legionella pneumophila replication in a murine model of legionellosis","volume":"65","author":"Brieland","year":"1997","journal-title":"Infect. Immun."}],"container-title":["M\u00e9decine et Maladies Infectieuses"],"original-title":[],"language":"fr","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0399077X05003458?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0399077X05003458?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T01:01:04Z","timestamp":1759971664000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0399077X05003458"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,4]]},"references-count":25,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2006,4]]}},"alternative-id":["S0399077X05003458"],"URL":"https:\/\/doi.org\/10.1016\/j.medmal.2005.10.010","relation":{},"ISSN":["0399-077X"],"issn-type":[{"value":"0399-077X","type":"print"}],"subject":[],"published":{"date-parts":[[2006,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Multiplication intra-amibienne de\u00a0Legionella\u00a0pneumophila et\u00a0r\u00f4le potentiel des\u00a0amibes dans\u00a0la\u00a0transmission de\u00a0la\u00a0l\u00e9gionellose","name":"articletitle","label":"Article Title"},{"value":"M\u00e9decine et Maladies Infectieuses","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.medmal.2005.10.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2006 Elsevier SAS. All rights reserved.","name":"copyright","label":"Copyright"}]}}