{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T10:17:46Z","timestamp":1760955466676,"version":"build-2065373602"},"reference-count":34,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2014,4,1]],"date-time":"2014-04-01T00:00:00Z","timestamp":1396310400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,4,1]],"date-time":"2014-04-01T00:00:00Z","timestamp":1396310400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.fr","em-consulte.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["M\u00e9decine et Maladies Infectieuses"],"published-print":{"date-parts":[[2014,4]]},"DOI":"10.1016\/j.medmal.2014.01.013","type":"journal-article","created":{"date-parts":[[2014,3,22]],"date-time":"2014-03-22T19:01:45Z","timestamp":1395514905000},"page":"159-166","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"title":["Gram-negative bacteremia: Which empirical antibiotic therapy?"],"prefix":"10.1016","volume":"44","author":[{"given":"M.","family":"Shoai Tehrani","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Hajage","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V.","family":"Fihman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Tankovic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Cau","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.","family":"Day","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Visseaux","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Carbonnelle","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Kouatchet","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V.","family":"Cattoir","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.X.","family":"Nhan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Corvec","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Jacquier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Jaur\u00e9guy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Le Monnier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Morand","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.R.","family":"Zahar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"12","key":"10.1016\/j.medmal.2014.01.013_bib0005","doi-asserted-by":"crossref","first-page":"5099","DOI":"10.1128\/AAC.00565-10","article-title":"National multicenter study of predictors and outcomes of bacteremia upon hospital admission caused by Enterobacteriaceaeceae producing extended-spectrum beta-lactamases","volume":"54","author":"Marchaim","year":"2010","journal-title":"Antimicrob Agents Chemother"},{"issue":"4","key":"10.1016\/j.medmal.2014.01.013_bib0010","doi-asserted-by":"crossref","first-page":"1257","DOI":"10.1128\/AAC.50.4.1257-1262.2006","article-title":"Clinical and economic impact of bacteremia with extended-spectrum beta-lactamase-producing Enterobacteriaceaeceae","volume":"50","author":"Schwaber","year":"2006","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.medmal.2014.01.013_bib0015","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1016\/j.amjmed.2010.03.021","article-title":"The clinical and prognostic importance of positive blood cultures in adults","volume":"123","author":"Pien","year":"2010","journal-title":"Am J Med"},{"key":"10.1016\/j.medmal.2014.01.013_bib0020","doi-asserted-by":"crossref","first-page":"1205","DOI":"10.1093\/jac\/dkp108","article-title":"Nationwide survey of extended-spectrum beta-lactamase-producing Enterobacteriaceaeceae in the French community setting","volume":"63","author":"Arpin","year":"2009","journal-title":"J Antimicrob Chemother"},{"issue":"2","key":"10.1016\/j.medmal.2014.01.013_bib0025","first-page":"172","article-title":"Addressing the challenge of extended-spectrum beta-lactamases","volume":"10","author":"Zahar","year":"2009","journal-title":"Curr Opin Investig Drugs"},{"issue":"2","key":"10.1016\/j.medmal.2014.01.013_bib0030","first-page":"57","article-title":"Bacteraemia due to Escherichia coli producing extended-spectrum beta-lactamases (ESBL): clinical relevance and today's insights","volume":"24","author":"Garc\u00eda-Hern\u00e1ndez","year":"2011","journal-title":"Rev Esp Quimioter"},{"key":"10.1016\/j.medmal.2014.01.013_bib0035","doi-asserted-by":"crossref","first-page":"1407","DOI":"10.1086\/508877","article-title":"Bacteremia due to extended-spectrum beta-lactamase-producing Escherichia coli in the CTX-M era: a new clinical challenge","volume":"43","author":"Rodriguez-Bano","year":"2006","journal-title":"Clin Infect Dis"},{"issue":"5","key":"10.1016\/j.medmal.2014.01.013_bib0040","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1111\/j.1469-0691.2005.01102.x","article-title":"Clinical features and outcome of patients with community-acquired Pseudomonas aeruginosa bacteraemia","volume":"1","author":"Kang","year":"2005","journal-title":"Clin Microbiol Infect"},{"key":"10.1016\/j.medmal.2014.01.013_bib0045","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1007\/s10096-003-1084-2","article-title":"Risk factors for the development of extended-spectrum beta-lactamase-producing bacteria in non-hospitalized patients","volume":"23","author":"Colodner","year":"2004","journal-title":"Eur J Clin Microbiol Infect Dis"},{"issue":"9","key":"10.1016\/j.medmal.2014.01.013_bib0050","doi-asserted-by":"crossref","first-page":"1408","DOI":"10.1111\/j.1469-0691.2010.03089.x","article-title":"Epidemiology and clinical features of community-acquired, health care-associated and nosocomial bloodstream infections in tertiary and community hospitals","volume":"16","author":"Rodriguez-Bano","year":"2009","journal-title":"Clin Microbiol Infect"},{"issue":"5","key":"10.1016\/j.medmal.2014.01.013_bib0175","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/j.ajic.2008.03.002","article-title":"CDC\/NHSN surveillance definition of health care-associated infection and criteria for specific types of infections in the acute care setting","volume":"36","author":"Horan","year":"2008","journal-title":"Am J Infect Control"},{"issue":"5 Suppl.","key":"10.1016\/j.medmal.2014.01.013_bib0060","first-page":"e28","volume":"136","author":"Bone","year":"2009","journal-title":"Chest"},{"issue":"5","key":"10.1016\/j.medmal.2014.01.013_bib0065","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/0021-9681(87)90171-8","article-title":"A new method of classifying prognostic comorbidity in longitudinal studies: development and validation","volume":"40","author":"Charlson","year":"1987","journal-title":"J Chronic Dis"},{"key":"10.1016\/j.medmal.2014.01.013_bib0070","doi-asserted-by":"crossref","first-page":"791","DOI":"10.7326\/0003-4819-137-10-200211190-00007","article-title":"Health care-associated bloodstream infections in adults: a reason to change the accepted definition of community-acquired infections","volume":"137","author":"Friedman","year":"2002","journal-title":"Ann Intern Med"},{"year":"2010","series-title":"Recommandations (\u00e9dition de janvier 2010)","author":"Comite de l\u2019antibiogramme de la Soci\u00e9t\u00e9 fran\u00e7aise de microbiologie","key":"10.1016\/j.medmal.2014.01.013_bib0075"},{"year":"1993","series-title":"Classification and regression trees","author":"Breiman","key":"10.1016\/j.medmal.2014.01.013_bib0080"},{"issue":"6","key":"10.1016\/j.medmal.2014.01.013_bib0085","doi-asserted-by":"crossref","first-page":"1205","DOI":"10.1093\/jac\/dkp108","article-title":"Nationwide survey of extended-spectrum beta-lactamase-producing Enterobacteriaceaeceae in the French community setting","volume":"63","author":"Arpin","year":"2009","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.medmal.2014.01.013_bib0090","doi-asserted-by":"crossref","first-page":"1589","DOI":"10.1097\/01.CCM.0000217961.75225.E9","article-title":"Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock","volume":"34","author":"Kumar","year":"2006","journal-title":"Crit Care Med"},{"key":"10.1016\/j.medmal.2014.01.013_bib0095","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1086\/596709","article-title":"Gram-negative bacteremia upon hospital admission: when should Pseudomonas aeruginosa be suspected?","volume":"48","author":"Schechner","year":"2009","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.medmal.2014.01.013_bib0100","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/S0732-8893(01)00284-X","article-title":"Four-year prospective evaluation of community-acquired bacteremia: epidemiology, microbiology, and patient outcome","volume":"41","author":"Lark","year":"2001","journal-title":"Diagn Microbiol Infect Dis"},{"key":"10.1016\/j.medmal.2014.01.013_bib0105","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/j.medmal.2005.05.002","article-title":"Surveillance of antimicrobial resistance of bacteria isolated from bloodstream infections: data of the French National Observatory for Epidemiology of Bacterial Resistance to Antibiotics (ONERBA), 1998\u20132003","volume":"35","author":"Bertrand","year":"2005","journal-title":"Med Mal Infect"},{"issue":"7","key":"10.1016\/j.medmal.2014.01.013_bib0110","doi-asserted-by":"crossref","first-page":"3485","DOI":"10.1128\/AAC.00009-11","article-title":"Identifying patients harboring extended-spectrum-beta-lactamase-producing Enterobacteriaceae on hospital admission: derivation and validation of a scoring system","volume":"55","author":"Tumbarello","year":"2011","journal-title":"Antimicrob Agents Chemother"},{"issue":"Suppl. 2","key":"10.1016\/j.medmal.2014.01.013_bib0115","first-page":"ii41","article-title":"Non-susceptibility trends among Enterobacteriaceaeceae from bacteraemias in the UK and Ireland, 2001\u20132006","volume":"62","author":"Livermore","year":"2008","journal-title":"J Antimicrob Chemother"},{"issue":"1","key":"10.1016\/j.medmal.2014.01.013_bib0120","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1086\/649537","article-title":"Community-onset bacteremia due to extended-spectrum beta-lactamase-producing Escherichia coli: risk factors and prognosis","volume":"50","author":"Rodr\u00edguez-Ba\u00f1o","year":"2010","journal-title":"Clin Infect Dis"},{"issue":"4","key":"10.1016\/j.medmal.2014.01.013_bib0125","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1111\/j.1469-0691.2010.03298.x","article-title":"Bacteremia caused by third-generation cephalosporin-resistant Escherichia coli in France: prevalence, molecular epidemiology and clinical features","volume":"17","author":"Courpon-Cludinon","year":"2011","journal-title":"Clin Microbiol Infect"},{"issue":"4","key":"10.1016\/j.medmal.2014.01.013_bib0180","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1093\/jac\/dks464","article-title":"National multidrug-resistant bacteria (MDRB) surveillance in France through the RAISIN network: a 9-year experience","volume":"68","author":"Carbonne","year":"2013","journal-title":"J Antimicrob Chemother"},{"issue":"7","key":"10.1016\/j.medmal.2014.01.013_bib0135","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1086\/505921","article-title":"Comparison of unit-specific and hospital-wide antibiograms: potential implications for selection of empirical antimicrobial therapy","volume":"27","author":"Binkley","year":"2006","journal-title":"Infect Control Hosp Epidemiol"},{"key":"10.1016\/j.medmal.2014.01.013_bib0140","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1016\/S1473-3099(12)70151-2","article-title":"Aggressive versus conservative initiation of antimicrobial treatment in critically ill surgical patients with suspected intensive-care-unit-acquired infection: a quasi-experimental, before and after observational cohort study","volume":"12","author":"Hranjec","year":"2012","journal-title":"Lancet Infect Dis"},{"issue":"9","key":"10.1016\/j.medmal.2014.01.013_bib0145","doi-asserted-by":"crossref","first-page":"3590","DOI":"10.1128\/AAC.00115-10","article-title":"Influence of empiric therapy with a beta-lactam alone or combined with an aminoglycoside on prognosis of bacteremia due to Gram-negative microorganisms","volume":"54","author":"Mart\u00ednez","year":"2010","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.medmal.2014.01.013_bib0150","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1086\/377200","article-title":"Pseudomonas aeruginosa bacteremia: risk factors for mortality and influence of delayed receipt of effective antimicrobial therapy on clinical outcome","volume":"37","author":"Kang","year":"2003","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.medmal.2014.01.013_bib0155","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1016\/j.amjmed.2003.07.005","article-title":"Inappropriate initial antimicrobial therapy and its effect on survival in a clinical trial of immunomodulating therapy for severe sepsis","volume":"115","author":"Harbarth","year":"2003","journal-title":"Am J Med"},{"issue":"4","key":"10.1016\/j.medmal.2014.01.013_bib0160","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1097\/QCO.0b013e32833bfc44","article-title":"Molecular diagnosis of bloodstream infections: planning to (physically) reach the bedside","volume":"23","author":"Leggieri","year":"2010","journal-title":"Curr Opin Infect Dis"},{"issue":"4","key":"10.1016\/j.medmal.2014.01.013_bib0165","first-page":"311","article-title":"Evaluation of a commercial multiplex PCR test (SeptiFast) in the etiological diagnosis of community-onset bloodstream infections","volume":"23","author":"Josefson","year":"2011","journal-title":"Eur J Clin Microbiol Infect Dis"},{"issue":"12","key":"10.1016\/j.medmal.2014.01.013_bib0170","doi-asserted-by":"crossref","first-page":"1579","DOI":"10.1007\/s10096-011-1263-5","article-title":"Revisited distribution of non-fermenting Gram-negative bacilli clinical isolates","volume":"30","author":"Jacquier","year":"2011","journal-title":"Eur J Clin Microbiol Infect Dis"}],"container-title":["M\u00e9decine et Maladies Infectieuses"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0399077X14000274?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0399077X14000274?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T01:13:04Z","timestamp":1759972384000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0399077X14000274"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,4]]},"references-count":34,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2014,4]]}},"alternative-id":["S0399077X14000274"],"URL":"https:\/\/doi.org\/10.1016\/j.medmal.2014.01.013","relation":{},"ISSN":["0399-077X"],"issn-type":[{"type":"print","value":"0399-077X"}],"subject":[],"published":{"date-parts":[[2014,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Gram-negative bacteremia: Which empirical antibiotic therapy?","name":"articletitle","label":"Article Title"},{"value":"M\u00e9decine et Maladies Infectieuses","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.medmal.2014.01.013","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Elsevier Masson SAS. All rights reserved.","name":"copyright","label":"Copyright"}]}}