{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T06:20:45Z","timestamp":1791267645719,"version":"4.1.0"},"reference-count":40,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2015,3,1]],"date-time":"2015-03-01T00:00:00Z","timestamp":1425168000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,3,1]],"date-time":"2015-03-01T00:00:00Z","timestamp":1425168000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.fr","em-consulte.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["M\u00e9decine et Maladies Infectieuses"],"published-print":{"date-parts":[[2015,3]]},"DOI":"10.1016\/j.medmal.2015.01.015","type":"journal-article","created":{"date-parts":[[2015,2,23]],"date-time":"2015-02-23T22:11:00Z","timestamp":1424729460000},"page":"65-71","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":25,"title":["Legionnaires\u2019 disease in France"],"prefix":"10.1016","volume":"45","author":[{"given":"C.","family":"Camp\u00e8se","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Descours","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Lepoutre","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Beraud","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Maine","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Che","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Jarraud","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"22","key":"10.1016\/j.medmal.2015.01.015_bib0205","doi-asserted-by":"crossref","first-page":"1189","DOI":"10.1056\/NEJM197712012972201","article-title":"Legionnaires\u2019 disease: description of an epidemic of pneumonia","volume":"297","author":"Fraser","year":"1977","journal-title":"N Engl J Med"},{"issue":"3","key":"10.1016\/j.medmal.2015.01.015_bib0210","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/j.patbio.2009.04.005","article-title":"Legionella and legionnaires\u2019 disease: what do we know?","volume":"59","author":"Che","year":"2011","journal-title":"Pathol Biol (Paris)"},{"issue":"5","key":"10.1016\/j.medmal.2015.01.015_bib0215","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1016\/j.meegid.2009.05.004","article-title":"Legionella pneumophila: population genetics, phylogeny and genomics","volume":"9","author":"Gomez-Valero","year":"2009","journal-title":"Infect Genet Evol"},{"issue":"1","key":"10.1016\/j.medmal.2015.01.015_bib0220","doi-asserted-by":"crossref","first-page":"e30","DOI":"10.1016\/j.ijid.2010.09.007","article-title":"Progress in the surveillance and control of Legionella infection in France, 1998\u20132008","volume":"15","author":"Campese","year":"2011","journal-title":"Int J Infect Dis"},{"issue":"3","key":"10.1016\/j.medmal.2015.01.015_bib0225","doi-asserted-by":"crossref","first-page":"457","DOI":"10.3201\/eid1003.020707","article-title":"Legionella infection risk from domestic hot water","volume":"10","author":"Borella","year":"2004","journal-title":"Emerg Infect Dis"},{"issue":"3","key":"10.1016\/j.medmal.2015.01.015_bib0230","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1056\/NEJM199801153380317","article-title":"Legionnaires\u2019 disease","volume":"338","author":"Edelstein","year":"1998","journal-title":"N Engl J Med"},{"issue":"8","key":"10.1016\/j.medmal.2015.01.015_bib0235","doi-asserted-by":"crossref","first-page":"1481","DOI":"10.1017\/S0950268811000975","article-title":"Changing epidemiological trends of legionellosis in New Zealand, 1979\u20132009","volume":"140","author":"Graham","year":"2012","journal-title":"Epidemiol Infect"},{"issue":"37","key":"10.1016\/j.medmal.2015.01.015_bib0240","doi-asserted-by":"crossref","DOI":"10.2807\/ese.17.37.20271-en","article-title":"An outbreak of Legionnaires\u2019 disease associated with a display spa pool in retail premises, Stoke-on-Trent, United Kingdom, July\u00a02012","volume":"17","author":"Coetzee","year":"2012","journal-title":"Euro Surveill"},{"issue":"1","key":"10.1016\/j.medmal.2015.01.015_bib0245","doi-asserted-by":"crossref","first-page":"37","DOI":"10.3201\/eid0801.010176","article-title":"A large outbreak of Legionnaires\u2019 disease at a flower show, the Netherlands, 1999","volume":"8","author":"den Boer","year":"2002","journal-title":"Emerg Infect Dis"},{"issue":"8","key":"10.1016\/j.medmal.2015.01.015_bib0250","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1093\/oxfordjournals.aje.a116895","article-title":"Outbreak of Legionnaire's disease linked to a decorative fountain by molecular epidemiology","volume":"138","author":"Hlady","year":"1993","journal-title":"Am J Epidemiol"},{"issue":"41","key":"10.1016\/j.medmal.2015.01.015_bib0255","doi-asserted-by":"crossref","first-page":"20293","DOI":"10.2807\/ese.17.41.20293-en","article-title":"Humidifier-associated paediatric Legionnaires\u2019 disease, Israel, February\u00a02012","volume":"17","author":"Moran-Gilad","year":"2012","journal-title":"Euro Surveill"},{"issue":"1","key":"10.1016\/j.medmal.2015.01.015_bib0260","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1086\/498575","article-title":"A community-wide outbreak of legionnaires disease linked to industrial cooling towers \u2013 how far can contaminated aerosols spread?","volume":"193","author":"Nguyen","year":"2006","journal-title":"J Infect Dis"},{"issue":"1","key":"10.1016\/j.medmal.2015.01.015_bib0265","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1086\/524016","article-title":"An outbreak of legionnaires disease caused by long-distance spread from an industrial air scrubber in Sarpsborg, Norway","volume":"46","author":"Nygard","year":"2008","journal-title":"Clin Infect Dis"},{"issue":"11","key":"10.1016\/j.medmal.2015.01.015_bib0270","doi-asserted-by":"crossref","first-page":"566","DOI":"10.5694\/j.1326-5377.2004.tb06093.x","article-title":"An outbreak of Legionnaires\u2019 disease at the Melbourne Aquarium. April\u00a02000: investigation and case-control studies","volume":"180","author":"Greig","year":"2004","journal-title":"Med J Aust"},{"issue":"12","key":"10.1016\/j.medmal.2015.01.015_bib0275","doi-asserted-by":"crossref","first-page":"2066","DOI":"10.1086\/498248","article-title":"It's not the heat, it's the humidity: wet weather increases legionellosis risk in the greater Philadelphia metropolitan area","volume":"192","author":"Fisman","year":"2005","journal-title":"J Infect Dis"},{"issue":"7","key":"10.1016\/j.medmal.2015.01.015_bib0280","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.1017\/S095026880800157X","article-title":"Weather patterns and Legionnaires\u2019 disease: a meteorological study","volume":"137","author":"Ricketts","year":"2009","journal-title":"Epidemiol Infect"},{"issue":"3","key":"10.1016\/j.medmal.2015.01.015_bib0285","doi-asserted-by":"crossref","first-page":"990","DOI":"10.1378\/chest.12-2820","article-title":"Incidence and risk factors of Legionella pneumophila pneumonia during anti-tumor necrosis factor therapy: a prospective French study","volume":"144","author":"Lanternier","year":"2013","journal-title":"Chest"},{"key":"10.1016\/j.medmal.2015.01.015_bib0290","unstructured":"Campese C. Bilan des cas de l\u00e9gionellose survenus en France en 2011. Saint Maurice: Institut de veille sanitaire [mis \u00e0 jour le 22\/05\/2012]. Accessed on 09\/01\/2013. URL: http:\/\/www.invs.sante.fr\/Dossiers-thematiques\/Maladies-infectieuses\/Infections-respiratoires\/Legionellose\/Donnees\/Bilan-des-cas-de-legionellose-survenus-en-France-en-2011."},{"issue":"11","key":"10.1016\/j.medmal.2015.01.015_bib0295","first-page":"505","article-title":"Comparative analyses of Legionella species identifies genetic features of strains causing Legionnaires inverted question mark disease","volume":"15","author":"Gomez-Valero","year":"2014","journal-title":"Genome Biol"},{"issue":"3","key":"10.1016\/j.medmal.2015.01.015_bib0300","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1101\/gr.7229808","article-title":"Multigenome analysis identifies a worldwide-distributed epidemic Legionella pneumophila clone that emerged within a highly diverse species","volume":"18","author":"Cazalet","year":"2008","journal-title":"Genome Res"},{"key":"10.1016\/j.medmal.2015.01.015_bib0305","doi-asserted-by":"crossref","first-page":"208","DOI":"10.3389\/fmicb.2011.00208","article-title":"Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions","volume":"2","author":"Gomez-Valero","year":"2011","journal-title":"Front Microbiol"},{"key":"10.1016\/j.medmal.2015.01.015_bib0310","unstructured":"Phin N, Parry-Ford F, Harrison T, Stagg HR, Zhang N, Kumar K, et al. Epidemiology and clinical management of Legionnaires\u2019 disease (1474\u20134457 [Electronic])."},{"issue":"4","key":"10.1016\/j.medmal.2015.01.015_bib0315","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1183\/09031936.00076911","article-title":"Factors associated with hospital mortality in community-acquired legionellosis in France","volume":"39","author":"Chidiac","year":"2012","journal-title":"Eur Respir J"},{"issue":"12","key":"10.1016\/j.medmal.2015.01.015_bib0320","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1007\/s10096-002-0839-5","article-title":"Factors related to persistence of Legionella urinary antigen excretion in patients with legionnaires\u2019 disease","volume":"21","author":"Sopena","year":"2002","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"10.1016\/j.medmal.2015.01.015_bib0325","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1007\/978-1-62703-161-5_2","article-title":"Identification of legionella in clinical samples","volume":"954","author":"Jarraud","year":"2013","journal-title":"Methods Mol Biol"},{"issue":"2","key":"10.1016\/j.medmal.2015.01.015_bib0330","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1128\/JCM.41.2.838-840.2003","article-title":"Clinical utility of urinary antigen detection for diagnosis of community-acquired, travel-associated, and nosocomial legionnaires\u2019 disease","volume":"41","author":"Helbig","year":"2003","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.medmal.2015.01.015_bib0335","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.mimet.2014.01.001","article-title":"Evaluation of BMPA, MWY, GVPC and BCYE media for the isolation of Legionella species from respiratory samples","volume":"98","author":"Descours","year":"2014","journal-title":"J Microbiol Methods"},{"issue":"5","key":"10.1016\/j.medmal.2015.01.015_bib0340","doi-asserted-by":"crossref","first-page":"1725","DOI":"10.1128\/JCM.06531-11","article-title":"Contribution of amoebic coculture to recovery of Legionella isolates from respiratory samples: prospective analysis over a period of 32\u00a0months","volume":"50","author":"Descours","year":"2012","journal-title":"J Clin Microbiol"},{"issue":"5","key":"10.1016\/j.medmal.2015.01.015_bib0345","doi-asserted-by":"crossref","first-page":"1708","DOI":"10.1128\/AEM.02261-10","article-title":"Specific real-time PCR for simultaneous detection and identification of Legionella pneumophila serogroup\u00a01 in water and clinical samples","volume":"77","author":"Merault","year":"2011","journal-title":"Appl Environ Microbiol"},{"issue":"4","key":"10.1016\/j.medmal.2015.01.015_bib0350","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1046\/j.1469-0691.2000.00041-2.x","article-title":"Detection of Legionella pneumophila DNA in urine and serum samples from patients with pneumonia","volume":"6","author":"Matsiota-Bernard","year":"2000","journal-title":"Clin Microbiol Infect"},{"key":"10.1016\/j.medmal.2015.01.015_bib0355","unstructured":"Afssaps. Mise au point. Traitement antibiotique de la l\u00e9gionellose chez l\u2019adulte. Saint Denis: Afssaps [mis \u00e0 jour le 06\/2011]. Accessed on 09\/01\/2013. URL: http:\/\/ansm.sante.fr\/var\/ansm_site\/storage\/original\/application\/5e0a0a6ce0725ba42387dc31a14551eb.pdf."},{"key":"10.1016\/j.medmal.2015.01.015_bib0360","unstructured":"Conseil sup\u00e9rieur d\u2019hygi\u00e8ne publique de France section des maladies transmissibles. Avis relatif \u00e0 la place de l\u2019antibioprophylaxie dans la pr\u00e9vention des l\u00e9gionelloses nosocomiales. 18\/03\/2005. Accessed on 10\/11\/2014. URL: http:\/\/www.sante.gouv.fr\/dossiers\/cshpf\/a_mt_180305_legionellose_prophy.pdf."},{"issue":"10","key":"10.1016\/j.medmal.2015.01.015_bib0365","doi-asserted-by":"crossref","first-page":"20417","DOI":"10.2807\/ese.18.10.20417-en","article-title":"Legionnaires disease in Europe, 2009\u20132010","volume":"18","author":"Beaute","year":"2013","journal-title":"Euro Surveill"},{"key":"10.1016\/j.medmal.2015.01.015_bib0370","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1007\/978-1-62703-161-5_6","article-title":"Typing methods for legionella","volume":"954","author":"Luck","year":"2013","journal-title":"Methods Mol Biol"},{"issue":"8","key":"10.1016\/j.medmal.2015.01.015_bib0375","doi-asserted-by":"crossref","first-page":"2017","DOI":"10.1007\/s10096-011-1535-0","article-title":"Application of Legionella pneumophila-specific quantitative real-time PCR combined with direct amplification and sequence-based typing in the diagnosis and epidemiological investigation of Legionnaires\u2019 disease","volume":"31","author":"Mentasti","year":"2012","journal-title":"Eur J Clin Microbiol Infect Dis"},{"issue":"4","key":"10.1016\/j.medmal.2015.01.015_bib0380","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1128\/JCM.02071-08","article-title":"Evaluation of a nested-PCR-derived sequence-based typing method applied directly to respiratory samples from patients with Legionnaires\u2019 disease","volume":"47","author":"Ginevra","year":"2009","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.medmal.2015.01.015_bib0385","unstructured":"Minist\u00e8re des affaires sociales et de la sant\u00e9, Direction g\u00e9n\u00e9rale de la sant\u00e9. DGS\/EA4 no\u00a02014-167 du 23\u00a0mai\u00a02014 relative \u00e0 la diffusion du guide du Haut Conseil de la sant\u00e9 publique (HCSP) pour l\u2019investigation et l\u2019aide \u00e0 la gestion sur le risque li\u00e9 aux l\u00e9gionelles. 23\/05\/2014. Accessed on 10\/11\/2014. URL: http:\/\/www.sante.gouv.fr\/fichiers\/bo\/2014\/14-08\/ste_20140008_0000_0103.pdf."},{"issue":"12","key":"10.1016\/j.medmal.2015.01.015_bib0390","doi-asserted-by":"crossref","first-page":"2644","DOI":"10.1017\/S0950268813000502","article-title":"Legionnaires\u2019 disease in France: sensitivity of the mandatory notification has improved over the last decade","volume":"141","author":"Campese","year":"2013","journal-title":"Epidemiol Infect"},{"key":"10.1016\/j.medmal.2015.01.015_bib0395","first-page":"325","article-title":"La l\u00e9gionellose en France\u00a0: augmentation du nombre de cas en 2010","volume":"29\u201330","author":"Campese","year":"2011","journal-title":"Bull Epidedemiol Hebd"},{"key":"10.1016\/j.medmal.2015.01.015_bib0400","doi-asserted-by":"crossref","unstructured":"Cassier P, Campese C, Le Strat Y, Che D, Ginevra C, Etienne J, et al. Epidemiological characteristics associated with ST23 clones compared to ST1 and ST47 clones of Legionnaires\u2019 disease cases in France. New microbes and new infections. \u00c0 para\u00eetre en 2014. DOI: 10.1016\/j.nmni.2014.10.006.","DOI":"10.1016\/j.nmni.2014.10.006"}],"container-title":["M\u00e9decine et Maladies Infectieuses"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0399077X15000220?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0399077X15000220?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T01:13:15Z","timestamp":1759972395000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0399077X15000220"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,3]]},"references-count":40,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2015,3]]}},"alternative-id":["S0399077X15000220"],"URL":"https:\/\/doi.org\/10.1016\/j.medmal.2015.01.015","relation":{},"ISSN":["0399-077X"],"issn-type":[{"value":"0399-077X","type":"print"}],"subject":[],"published":{"date-parts":[[2015,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Legionnaires\u2019 disease in France","name":"articletitle","label":"Article Title"},{"value":"M\u00e9decine et Maladies Infectieuses","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.medmal.2015.01.015","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier Masson SAS. All rights reserved.","name":"copyright","label":"Copyright"}]}}