{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,9]],"date-time":"2026-04-09T12:49:03Z","timestamp":1775738943805,"version":"3.50.1"},"reference-count":22,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2019,5,1]],"date-time":"2019-05-01T00:00:00Z","timestamp":1556668800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,5,1]],"date-time":"2019-05-01T00:00:00Z","timestamp":1556668800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2019,2,12]],"date-time":"2019-02-12T00:00:00Z","timestamp":1549929600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.fr","em-consulte.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["M\u00e9decine et Maladies Infectieuses"],"published-print":{"date-parts":[[2019,5]]},"DOI":"10.1016\/j.medmal.2019.01.011","type":"journal-article","created":{"date-parts":[[2019,2,18]],"date-time":"2019-02-18T09:08:56Z","timestamp":1550480936000},"page":"194-201","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"title":["PRISM study: Comparison of a nystatin-neomycin-polymyxin B combination with miconazole for the empirical treatment of infectious vaginitis"],"prefix":"10.1016","volume":"49","author":[{"given":"J.M.","family":"Bohbot","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Goubard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Aubin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y.","family":"Mas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Coatantiec","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.","family":"Lucas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Verri\u00e8re","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.medmal.2019.01.011_bib0115","doi-asserted-by":"crossref","first-page":"1244","DOI":"10.1056\/NEJMcp053720","article-title":"Clinical practice. Acute vulvovaginitis","volume":"355","author":"Eckert","year":"2006","journal-title":"N Engl J Med"},{"key":"10.1016\/j.medmal.2019.01.011_bib0120","first-page":"1095","article-title":"Diagnosis of vaginitis","volume":"62","author":"Egan","year":"2000","journal-title":"Am Fam Physician"},{"key":"10.1016\/j.medmal.2019.01.011_bib0125","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1111\/j.1471-0528.2002.00432.x","article-title":"Definition of a type of abnormal vaginal flora that is distinct from bacterial vaginosis: aerobic vaginitis","volume":"109","author":"Donders","year":"2002","journal-title":"BJOG"},{"key":"10.1016\/j.medmal.2019.01.011_bib0130","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1007\/s11908-013-0325-5","article-title":"Mixed vaginitis-more than coinfection and with therapeutic implications","volume":"15","author":"Sobel","year":"2013","journal-title":"Curr Infect Dis Rep"},{"key":"10.1016\/j.medmal.2019.01.011_bib0135","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1016\/j.gyobfe.2011.08.001","article-title":"The etiologic diversity of vaginitis","volume":"40","author":"Bohbot","year":"2012","journal-title":"Gynecol Obstet Fertil"},{"key":"10.1016\/j.medmal.2019.01.011_bib0140","doi-asserted-by":"crossref","first-page":"1004","DOI":"10.1016\/j.ajog.2004.02.015","article-title":"Predictive value of the clinical diagnosis of lower genital tract infection in women","volume":"190","author":"Landers","year":"2004","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.medmal.2019.01.011_bib0145","doi-asserted-by":"crossref","first-page":"1929","DOI":"10.1001\/archinte.1990.00390200111021","article-title":"The limited value of symptoms and signs in the diagnosis of vaginal infections","volume":"150","author":"Schaaf","year":"1990","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.medmal.2019.01.011_bib0150","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1007\/s004040000157","article-title":"Value of vaginal culture in management of acute vaginitis","volume":"265","author":"Lurie","year":"2001","journal-title":"Arch Gynecol Obstet"},{"key":"10.1016\/j.medmal.2019.01.011_bib0155","doi-asserted-by":"crossref","first-page":"1896","DOI":"10.1056\/NEJM199712253372607","article-title":"Vaginitis","volume":"337","author":"Sobel","year":"1997","journal-title":"N Engl J Med"},{"key":"10.1016\/j.medmal.2019.01.011_bib0160","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1097\/00003081-199303000-00016","article-title":"Vaginal flora in health and disease","volume":"36","author":"Larsen","year":"1993","journal-title":"Clin Obstet Gynecol"},{"key":"10.1016\/j.medmal.2019.01.011_bib0165","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1186\/1471-2458-11-63","article-title":"Patient preferences and treatment safety for uncomplicated vulvovaginal candidiasis in primary health care","volume":"11","author":"Del-Cura Gonzalez","year":"2011","journal-title":"BMC Public Health"},{"key":"10.1016\/j.medmal.2019.01.011_bib0170","first-page":"161","article-title":"Use of a local antibiotic combination in the treatment of mycotic vaginitis and mixed vaginitis","volume":"87","author":"Bruhat","year":"1992","journal-title":"Rev Fr Gynecol Obstet"},{"key":"10.1016\/j.medmal.2019.01.011_bib0175","doi-asserted-by":"crossref","first-page":"445","DOI":"10.4236\/ojog.2014.47065","article-title":"Nystatin-neomycin-polymyxin combination: efficacy and tolerance as 1st-line local treatment of infectious vaginitis","volume":"4","author":"Bohbot","year":"2014","journal-title":"Open J Obstet Gynecol"},{"issue":"2","key":"10.1016\/j.medmal.2019.01.011_bib0180","first-page":"3","article-title":"Polygynax in the treatment of vaginal infections in pregnant and non-pregnant women-clinical experience","volume":"55","author":"Popovski","year":"2016","journal-title":"Akush Ginekol (Sofiia)"},{"key":"10.1016\/j.medmal.2019.01.011_bib0185","first-page":"83","article-title":"Aetiology & risk factors of recurrent vaginitis & its association with various contraceptive methods","volume":"131","author":"Thulkar","year":"2010","journal-title":"Indian J Med Res"},{"key":"10.1016\/j.medmal.2019.01.011_bib0190","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1155\/S1064744901000187","article-title":"The classic approach to diagnosis of vulvovaginitis: a critical analysis","volume":"9","author":"Bornstein","year":"2001","journal-title":"Infect Dis Obstet Gynecol"},{"key":"10.1016\/j.medmal.2019.01.011_bib0195","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1016\/0002-9378(93)90340-O","article-title":"Diagnostic microbiology of bacterial vaginosis","volume":"169","author":"Hillier","year":"1993","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.medmal.2019.01.011_bib0200","doi-asserted-by":"crossref","first-page":"1368","DOI":"10.1001\/jama.291.11.1368","article-title":"Evaluation of vaginal complaints","volume":"291","author":"Anderson","year":"2004","journal-title":"JAMA"},{"key":"10.1016\/j.medmal.2019.01.011_bib0205","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1007\/s11908-005-0048-3","article-title":"Advances in diagnosing vaginitis: development of a new algorithm","volume":"7","author":"Nyirjesy","year":"2005","journal-title":"Curr Infect Dis Rep"},{"key":"10.1016\/j.medmal.2019.01.011_bib0210","first-page":"402","article-title":"Self-reported yeast symptoms compared with clinical wet mount analysis and vaginal yeast culture in a specialty clinic setting","volume":"53","author":"Hoffstetter","year":"2008","journal-title":"J Reprod Med"},{"key":"10.1016\/j.medmal.2019.01.011_bib0215","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/j.gyobfe.2014.12.007","article-title":"Management of vaginal infection following failure of a probabilistic treatment: is the vaginal swab really useful?","volume":"43","author":"Bretelle","year":"2015","journal-title":"Gynecol Obstet Fertil"},{"key":"10.1016\/j.medmal.2019.01.011_bib0220","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1016\/S0399-077X(03)00018-0","article-title":"Diagnosis of vaginitis in general practice: compared clinical and bacterial data","volume":"33","author":"Boisivon","year":"2003","journal-title":"Med Mal Infect"}],"container-title":["M\u00e9decine et Maladies Infectieuses"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0399077X18301860?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0399077X18301860?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T01:17:12Z","timestamp":1759972632000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0399077X18301860"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,5]]},"references-count":22,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2019,5]]}},"alternative-id":["S0399077X18301860"],"URL":"https:\/\/doi.org\/10.1016\/j.medmal.2019.01.011","relation":{},"ISSN":["0399-077X"],"issn-type":[{"value":"0399-077X","type":"print"}],"subject":[],"published":{"date-parts":[[2019,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"PRISM study: Comparison of a nystatin-neomycin-polymyxin B combination with miconazole for the empirical treatment of infectious vaginitis","name":"articletitle","label":"Article Title"},{"value":"M\u00e9decine et Maladies Infectieuses","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.medmal.2019.01.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 The Authors. Published by Elsevier Masson SAS.","name":"copyright","label":"Copyright"}]}}