{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T15:53:14Z","timestamp":1792511594918,"version":"4.5.0"},"reference-count":78,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2019,8,1]],"date-time":"2019-08-01T00:00:00Z","timestamp":1564617600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,8,1]],"date-time":"2019-08-01T00:00:00Z","timestamp":1564617600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,7,24]],"date-time":"2020-07-24T00:00:00Z","timestamp":1595548800000},"content-version":"am","delay-in-days":358,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.fr","em-consulte.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["M\u00e9decine et Maladies Infectieuses"],"published-print":{"date-parts":[[2019,8]]},"DOI":"10.1016\/j.medmal.2019.05.001","type":"journal-article","created":{"date-parts":[[2019,5,30]],"date-time":"2019-05-30T23:01:31Z","timestamp":1559257291000},"page":"335-346","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":71,"title":["Lyme borreliosis and other tick-borne diseases. Guidelines from the French scientific societies (II). Biological diagnosis, treatment, persistent symptoms after documented or suspected Lyme borreliosis"],"prefix":"10.1016","volume":"49","author":[{"given":"B.","family":"Jaulhac","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Saunier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Caumes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Bouiller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.F.","family":"Gehanno","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Rabaud","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Perrot","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Eldin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"de Broucker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Roblot","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Toubiana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Sellal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Vuillemet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Sordet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.","family":"Fantin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Lina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Sobas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"X.","family":"Gocko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Figoni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Chirouze","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.","family":"Hansmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V.","family":"Hentgen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Cathebras","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Dieudonn\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"O.","family":"Picone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.","family":"Bodaghi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.P.","family":"Gangneux","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.","family":"Degeilh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Partouche","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Lenormand","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Sotto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Raffetin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.J.","family":"Monsuez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Michel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"Boulanger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Lemogne","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Tattevin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.medmal.2019.05.001_bib0395","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.medmal.2018.11.011","article-title":"Review of European and American guidelines for the diagnosis of Lyme borreliosis","volume":"49","author":"Eldin","year":"2019","journal-title":"Med Mal Infect"},{"key":"10.1016\/j.medmal.2019.05.001_bib0400","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1023\/A:1007404620701","article-title":"Longterm survey (7 years) in a population at risk for Lyme borreliosis: what happens to the seropositive individuals?","volume":"14","author":"Fahrer","year":"1998","journal-title":"Eur J Epidemiol"},{"key":"10.1016\/j.medmal.2019.05.001_bib0405","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1186\/s12879-016-1468-4","article-title":"The diagnostic accuracy of serological tests for Lyme borreliosis in Europe: a systematic review and meta-analysis","volume":"16","author":"Leeflang","year":"2016","journal-title":"BMC Infect Dis"},{"key":"10.1016\/j.medmal.2019.05.001_bib0410","doi-asserted-by":"crossref","first-page":"e0168613","DOI":"10.1371\/journal.pone.0168613","article-title":"The Accuracy of Diagnostic Tests for Lyme Disease in Humans. A Systematic Review and Meta-Analysis of North American Research","volume":"11","author":"Waddell","year":"2016","journal-title":"PLoS One"},{"key":"10.1016\/j.medmal.2019.05.001_bib0415","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/j.cmi.2017.08.025","article-title":"To test or not to test? Laboratory support for the diagnosis of Lyme borreliosis: a position paper of ESGBOR, the ESCMID study Group for Lyme borreliosis","volume":"24","author":"Dessau","year":"2018","journal-title":"Clin Microbiol Infect"},{"key":"10.1016\/j.medmal.2019.05.001_bib0420","doi-asserted-by":"crossref","first-page":"1236","DOI":"10.1111\/j.1469-0691.2011.03749.x","article-title":"High frequency of false positive IgM immunoblots for Borrelia burgdorferi in clinical practice","volume":"18","author":"Seriburi","year":"2012","journal-title":"Clin Microbiol Infect"},{"key":"10.1016\/j.medmal.2019.05.001_bib0425","doi-asserted-by":"crossref","DOI":"10.1016\/j.cmi.2019.02.020","article-title":"Lyme Disease Overdiagnosis in a Large Healthcare System: A Population-based. Retrospective Study","author":"Webber","year":"2019","journal-title":"Clin Microbiol Infect"},{"key":"10.1016\/j.medmal.2019.05.001_bib0430","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1128\/CVI.00367-10","article-title":"Acute parvovirus B19 infection causes nonspecificity frequently in Borrelia and less often in Salmonella and Campylobacter serology, posing a problem in diagnosis of infectious arthropathy","volume":"18","author":"Tuuminen","year":"2011","journal-title":"Clin Vaccine Immunol"},{"key":"10.1016\/j.medmal.2019.05.001_bib0435","article-title":"Characteristics and clinical outcomes after treatment of a national cohort of PCR-positive Lyme arthritis","author":"Grillon","year":"2018","journal-title":"Semin Arthritis Rheum"},{"key":"10.1016\/j.medmal.2019.05.001_bib0440","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1007\/s10096-003-0943-1","article-title":"Two unusual cases of diffuse acrodermatitis chronica atrophicans seronegative for Lyme borreliosis","volume":"22","author":"Berger","year":"2003","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"10.1016\/j.medmal.2019.05.001_bib0445","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1007\/s00296-007-0333-6","article-title":"Seronegative Lyme arthritis","volume":"27","author":"Holl-Wieden","year":"2007","journal-title":"Rheumatol Int"},{"key":"10.1016\/j.medmal.2019.05.001_bib0450","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1007\/s15010-007-6121-0","article-title":"Seronegative Lyme neuroborreliosis in a patient on treatment for chronic lymphatic leukemia","volume":"35","author":"Harrer","year":"2007","journal-title":"Infection"},{"key":"10.1016\/j.medmal.2019.05.001_bib0455","doi-asserted-by":"crossref","first-page":"1705","DOI":"10.1093\/cid\/ciu703","article-title":"A comparison of lyme disease serologic test results from 4 laboratories in patients with persistent symptoms after antibiotic treatment","volume":"59","author":"Fallon","year":"2014","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.medmal.2019.05.001_bib0460","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/j.idc.2015.02.005","article-title":"Laboratory diagnosis of Lyme disease: advances and challenges","volume":"29","author":"Marques","year":"2015","journal-title":"Infect Dis Clin North Am"},{"key":"10.1016\/j.medmal.2019.05.001_bib0465","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1586\/14737159.2015.989837","article-title":"Lyme disease: diagnostic issues and controversies","volume":"15","author":"Aguero-Rosenfeld","year":"2015","journal-title":"Expert Rev Mol Diagn"},{"key":"10.1016\/j.medmal.2019.05.001_bib0470","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1111\/j.1468-1331.2009.02862.x","article-title":"EFNS guidelines on the diagnosis and management of European Lyme neuroborreliosis","volume":"17","author":"Mygland","year":"2010","journal-title":"Eur J Neurol"},{"key":"10.1016\/j.medmal.2019.05.001_bib0475","first-page":"1408","volume":"82","author":"Khatchikian","year":"2014","journal-title":"Evidence for strain-specific immunity in patients treated for early lyme disease. Infect Immun"},{"key":"10.1016\/j.medmal.2019.05.001_bib0480","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1128\/CVI.00026-15","article-title":"Study of a Cohort of 1,886 Persons To Determine Changes in Antibody Reactivity to Borrelia burgdorferi 3 Months after a Tick Bite","volume":"22","author":"Dessau","year":"2015","journal-title":"Clin Vaccine Immunol"},{"key":"10.1016\/j.medmal.2019.05.001_bib0485","doi-asserted-by":"crossref","first-page":"1895","DOI":"10.1128\/JCM.38.5.1895-1900.2000","article-title":"Direct molecular typing of Borrelia burgdorferi sensu lato species in synovial samples from patients with lyme arthritis","volume":"38","author":"Jaulhac","year":"2000","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.medmal.2019.05.001_bib0490","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1016\/j.medmal.2006.01.019","article-title":"[Laboratory methods for the diagnosis of clinical forms of Lyme borreliosis]","volume":"37","author":"Assous","year":"2007","journal-title":"Med Mal Infect"},{"key":"10.1016\/j.medmal.2019.05.001_bib0495","doi-asserted-by":"crossref","first-page":"355","DOI":"10.2165\/0128071-200809060-00002","article-title":"Skin manifestations of lyme borreliosis: diagnosis and management","volume":"9","author":"Mullegger","year":"2008","journal-title":"Am J Clin Dermatol"},{"key":"10.1016\/j.medmal.2019.05.001_bib0500","doi-asserted-by":"crossref","first-page":"1234","DOI":"10.1016\/j.cmi.2018.04.007","article-title":"Diagnostic value of cerebrospinal fluid CXCL13 for acute Lyme neuroborreliosis. A systematic review and meta-analysis","volume":"24","author":"Rupprecht","year":"2018","journal-title":"Clin Microbiol Infect"},{"key":"10.1016\/j.medmal.2019.05.001_bib0505","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1089\/jir.2016.0101","article-title":"Chemokine CXC Ligand 13 in Cerebrospinal Fluid Can Be Used as an Early Diagnostic Biomarker for Lyme Neuroborreliosis: A Meta-Analysis","volume":"37","author":"Yang","year":"2017","journal-title":"J Interferon Cytokine Res"},{"key":"10.1016\/j.medmal.2019.05.001_bib0510","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1128\/jcm.32.3.715-720.1994","article-title":"Isolation of Borrelia burgdorferi from biopsy specimens taken from healthy-looking skin of patients with Lyme borreliosis","volume":"32","author":"Kuiper","year":"1994","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.medmal.2019.05.001_bib0515","doi-asserted-by":"crossref","first-page":"1290","DOI":"10.1016\/j.cmi.2018.02.028","article-title":"Comparison of phenoxymethylpenicillin, amoxicillin, and doxycycline for erythema migrans in general practice. A randomized controlled trial with a 1-year follow-up","volume":"24","author":"Eliassen","year":"2018","journal-title":"Clin Microbiol Infect"},{"key":"10.1016\/j.medmal.2019.05.001_bib0520","doi-asserted-by":"crossref","first-page":"1292","DOI":"10.1001\/jamadermatol.2018.3186","article-title":"Efficacy and Safety of Antibiotic Therapy in Early Cutaneous Lyme Borreliosis: A Network Meta-analysis","volume":"154","author":"Torbahn","year":"2018","journal-title":"JAMA Dermatol"},{"key":"10.1016\/j.medmal.2019.05.001_bib0525","doi-asserted-by":"crossref","first-page":"1352","DOI":"10.1093\/jac\/dkx534","article-title":"Oral doxycycline versus intravenous ceftriaxone for treatment of multiple erythema migrans: an open-label alternate-treatment observational trial","volume":"73","author":"Stupica","year":"2018","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.medmal.2019.05.001_bib0530","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1007\/s100960100476","article-title":"Disease expression of Lyme borreliosis in northeastern France","volume":"20","author":"Lipsker","year":"2001","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"10.1016\/j.medmal.2019.05.001_bib0535","doi-asserted-by":"crossref","first-page":"1050","DOI":"10.1001\/jamadermatol.2018.2306","article-title":"Comparison of Clinical Course and Treatment Outcome for Patients With Early Disseminated or Early Localized Lyme Borreliosis","volume":"154","author":"Stupica","year":"2018","journal-title":"JAMA Dermatol"},{"key":"10.1016\/j.medmal.2019.05.001_bib0540","doi-asserted-by":"crossref","first-page":"914","DOI":"10.1093\/cid\/ciw417","article-title":"Borrelial Lymphocytoma in Adult Patients","volume":"63","author":"Maraspin","year":"2016","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.medmal.2019.05.001_bib0545","article-title":"Cutaneous Lyme borreliosis: Guideline of the German Dermatology Society","volume":"15","author":"Hofmann","year":"2017","journal-title":"Ger Med Sci"},{"key":"10.1016\/j.medmal.2019.05.001_bib0550","first-page":"309","article-title":"Diagnosis and treatment of tick-borne diseases recommendations of the Polish Society of Epidemiology and Infectious Diseases","volume":"69","author":"Pancewicz","year":"2015","journal-title":"Przegl Epidemiol"},{"key":"10.1016\/j.medmal.2019.05.001_bib0555","article-title":"Antibiotics for the neurological complications of Lyme disease","volume":"12","author":"Cadavid","year":"2016","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.medmal.2019.05.001_bib0560","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.1212\/WNL.44.7.1203","article-title":"Comparison of intravenous penicillin G and oral doxycycline for treatment of Lyme neuroborreliosis","volume":"44","author":"Karlsson","year":"1994","journal-title":"Neurology"},{"key":"10.1016\/j.medmal.2019.05.001_bib0565","first-page":"464","article-title":"Treatment of Lyme borreliosis","volume":"236","author":"Kohlhepp","year":"1989","journal-title":"Randomized comparison of doxycycline and penicillin G. J Neurol"},{"key":"10.1016\/j.medmal.2019.05.001_bib0570","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1016\/S1474-4422(08)70119-4","article-title":"Oral doxycycline versus intravenous ceftriaxone for European Lyme neuroborreliosis: a multicentre, non-inferiority, double-blind, randomised trial","volume":"7","author":"Ljostad","year":"2008","journal-title":"Lancet Neurol"},{"key":"10.1016\/j.medmal.2019.05.001_bib0575","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1007\/BF01644967","article-title":"Penicillin G sodium and ceftriaxone in the treatment of neuroborreliosis in children--a prospective study","volume":"19","author":"Mullegger","year":"1991","journal-title":"Infection"},{"key":"10.1016\/j.medmal.2019.05.001_bib0580","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1007\/s10096-007-0340-2","article-title":"Duration of antibiotic treatment in disseminated Lyme borreliosis: a double-blind, randomized, placebo-controlled, multicenter clinical study","volume":"26","author":"Oksi","year":"2007","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"10.1016\/j.medmal.2019.05.001_bib0585","doi-asserted-by":"crossref","first-page":"1190","DOI":"10.1001\/archneur.1989.00520470044025","article-title":"Cefotaxime vs penicillin G for acute neurologic manifestations in Lyme borreliosis. A prospective randomized study","volume":"46","author":"Pfister","year":"1989","journal-title":"Arch Neurol"},{"key":"10.1016\/j.medmal.2019.05.001_bib0590","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1093\/infdis\/163.2.311","article-title":"Randomized comparison of ceftriaxone and cefotaxime in Lyme neuroborreliosis","volume":"163","author":"Pfister","year":"1991","journal-title":"J Infect Dis"},{"key":"10.1016\/j.medmal.2019.05.001_bib0595","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1007\/s00508-005-0361-8","article-title":"A comparison of two treatment regimens of ceftriaxone in late Lyme disease","volume":"117","author":"Dattwyler","year":"2005","journal-title":"Wien Klin Wochenschr"},{"key":"10.1016\/j.medmal.2019.05.001_bib0600","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1086\/649920","article-title":"Antibiotic treatment duration and long-term outcomes of patients with early lyme disease from a lyme disease-hyperendemic area","volume":"50","author":"Kowalski","year":"2010","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.medmal.2019.05.001_bib0605","doi-asserted-by":"crossref","first-page":"1249","DOI":"10.1111\/ene.12744","article-title":"Efficacy and safety of pharmacological treatments for acute Lyme neuroborreliosis - a systematic review","volume":"22","author":"Dersch","year":"2015","journal-title":"Eur J Neurol"},{"key":"10.1016\/j.medmal.2019.05.001_bib0610","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1186\/s12883-016-0708-y","article-title":"Efficacy and safety of pharmacological treatments for Lyme neuroborreliosis in children: a systematic review","volume":"16","author":"Dersch","year":"2016","journal-title":"BMC Neurol"},{"key":"10.1016\/j.medmal.2019.05.001_bib0615","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1016\/j.diagmicrobio.2018.03.016","article-title":"Outcome of facial palsy from Lyme disease in prospectively followed patients who had received corticosteroids","volume":"91","author":"Wormser","year":"2018","journal-title":"Diagn Microbiol Infect Dis"},{"key":"10.1016\/j.medmal.2019.05.001_bib0620","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1111\/j.1600-0404.2012.01690.x","article-title":"Risk factors for a non-favorable outcome after treated European neuroborreliosis","volume":"127","author":"Eikeland","year":"2013","journal-title":"Acta Neurol Scand"},{"key":"10.1016\/j.medmal.2019.05.001_bib0625","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1007\/s00415-015-7923-0","article-title":"Prevalence and spectrum of residual symptoms in Lyme neuroborreliosis after pharmacological treatment: a systematic review","volume":"263","author":"Dersch","year":"2016","journal-title":"J Neurol"},{"key":"10.1016\/j.medmal.2019.05.001_bib0630","article-title":"Long term survival, health, social functioning, and education in patients with European Lyme neuroborreliosis: nationwide population based cohort study","volume":"361","author":"Obel","year":"2018","journal-title":"BMJ"},{"key":"10.1016\/j.medmal.2019.05.001_bib0635","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1016\/j.diagmicrobio.2018.09.015","article-title":"How safe is doxycycline for young children or for pregnant or breastfeeding women?","volume":"93","author":"Wormser","year":"2019","journal-title":"Diagn Microbiol Infect Dis"},{"key":"10.1016\/j.medmal.2019.05.001_bib0640","doi-asserted-by":"crossref","first-page":"878","DOI":"10.1002\/art.1780370616","article-title":"Treatment of Lyme arthritis","volume":"37","author":"Steere","year":"1994","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.medmal.2019.05.001_bib0645","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/S1297-319X(03)00160-X","article-title":"Good outcomes of Lyme arthritis in 24 patients in an endemic area of Switzerland","volume":"71","author":"Renaud","year":"2004","journal-title":"Joint Bone Spine"},{"key":"10.1016\/j.medmal.2019.05.001_bib0650","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1007\/s100960050166","article-title":"Comparison of oral cefixime and intravenous ceftriaxone followed by oral amoxicillin in disseminated Lyme borreliosis","volume":"17","author":"Oksi","year":"1998","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"10.1016\/j.medmal.2019.05.001_bib0655","first-page":"98","article-title":"Long-term results in patients with Lyme arthritis following treatment with ceftriaxone","volume":"24","author":"Valesova","year":"1996","journal-title":"Infection"},{"key":"10.1016\/j.medmal.2019.05.001_bib0660","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1007\/BF01780666","article-title":"Success and failure in the treatment of acrodermatitis chronica atrophicans","volume":"24","author":"Aberer","year":"1996","journal-title":"Infection"},{"key":"10.1016\/j.medmal.2019.05.001_bib0665","doi-asserted-by":"crossref","first-page":"996","DOI":"10.1093\/cid\/ciu411","article-title":"Third-degree heart block associated with lyme carditis: review of published cases","volume":"59","author":"Forrester","year":"2014","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.medmal.2019.05.001_bib0670","first-page":"982","article-title":"Notes from the field: update on Lyme carditis, groups at high risk, and frequency of associated sudden cardiac death--United States","volume":"63","author":"Forrester","year":"2014","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"10.1016\/j.medmal.2019.05.001_bib0675","doi-asserted-by":"crossref","first-page":"1303","DOI":"10.1586\/14787210.2015.1081056","article-title":"Sexual transmission of Lyme disease: challenging the tickborne disease paradigm","volume":"13","author":"Stricker","year":"2015","journal-title":"Expert Rev Anti Infect Ther"},{"key":"10.1016\/j.medmal.2019.05.001_bib0680","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1016\/S0889-857X(21)01021-8","article-title":"Implications for the fetus","volume":"15","author":"MacDonald","year":"1989","journal-title":"Rheum Dis Clin North Am"},{"key":"10.1016\/j.medmal.2019.05.001_bib0685","doi-asserted-by":"crossref","first-page":"e0207067","DOI":"10.1371\/journal.pone.0207067","article-title":"A systematic review on the impact of gestational Lyme disease in humans on the fetus and newborn","volume":"13","author":"Waddell","year":"2018","journal-title":"PLoS One"},{"key":"10.1016\/j.medmal.2019.05.001_bib0690","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/0732-8893(95)00027-8","article-title":"Detection of Borrelia burgdorferi DNA by polymerase chain reaction in the urine and breast milk of patients with Lyme borreliosis","volume":"21","author":"Schmidt","year":"1995","journal-title":"Diagn Microbiol Infect Dis"},{"key":"10.1016\/j.medmal.2019.05.001_bib0695","doi-asserted-by":"crossref","first-page":"1209","DOI":"10.1056\/NEJMoa1505425","article-title":"Randomized Trial of Longer-Term Therapy for Symptoms Attributed to Lyme Disease","volume":"374","author":"Berende","year":"2016","journal-title":"N Engl J Med"},{"key":"10.1016\/j.medmal.2019.05.001_bib0700","doi-asserted-by":"crossref","first-page":"992","DOI":"10.1212\/01.WNL.0000284604.61160.2d","article-title":"A randomized, placebo-controlled trial of repeated IV antibiotic therapy for Lyme encephalopathy","volume":"70","author":"Fallon","year":"2008","journal-title":"Neurology"},{"key":"10.1016\/j.medmal.2019.05.001_bib0705","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1056\/NEJM200107123450202","article-title":"Two controlled trials of antibiotic treatment in patients with persistent symptoms and a history of Lyme disease","volume":"345","author":"Klempner","year":"2001","journal-title":"N Engl J Med"},{"key":"10.1016\/j.medmal.2019.05.001_bib0710","doi-asserted-by":"crossref","first-page":"1923","DOI":"10.1212\/01.WNL.0000071227.23769.9E","article-title":"Study and treatment of post Lyme disease (STOP-LD): a randomized double masked clinical trial","volume":"60","author":"Krupp","year":"2003","journal-title":"Neurology"},{"key":"10.1016\/j.medmal.2019.05.001_bib0715","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1086\/318138","article-title":"Death from inappropriate therapy for Lyme disease","volume":"31","author":"Patel","year":"2000","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.medmal.2019.05.001_bib0720","doi-asserted-by":"crossref","first-page":"1812","DOI":"10.1001\/jama.1993.03500140064037","article-title":"The overdiagnosis of Lyme disease","volume":"269","author":"Steere","year":"1993","journal-title":"JAMA"},{"key":"10.1016\/j.medmal.2019.05.001_bib0725","doi-asserted-by":"crossref","first-page":"354","DOI":"10.7326\/0003-4819-128-5-199803010-00003","article-title":"The consequences of overdiagnosis and overtreatment of Lyme disease: an observational study","volume":"128","author":"Reid","year":"1998","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.medmal.2019.05.001_bib0730","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1016\/j.cmi.2014.11.014","article-title":"Ticking the right boxes: classification of patients suspected of Lyme borreliosis at an academic referral center in the Netherlands","volume":"21","author":"Coumou","year":"2015","journal-title":"Clin Microbiol Infect"},{"key":"10.1016\/j.medmal.2019.05.001_bib0735","article-title":"Holistic approach in patients with presumed Lyme borreliosis leads to less than 10% of confirmation and more than 80% of antibiotics failure","author":"Haddad","year":"2018","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.medmal.2019.05.001_bib0740","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.medmal.2018.06.002","article-title":"Multidisciplinary management of patients presenting with Lyme disease suspicion","volume":"49","author":"Jacquet","year":"2019","journal-title":"Med Mal Infect"},{"key":"10.1016\/j.medmal.2019.05.001_bib0745","article-title":"Consultation for presumed Lyme borreliosis: the need for a multidisciplinary management","author":"Bouiller","year":"2018","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.medmal.2019.05.001_bib0750","doi-asserted-by":"crossref","first-page":"1493","DOI":"10.1001\/archinte.1996.00440130011002","article-title":"The Lyme disease controversy. Social and financial costs of misdiagnosis and mismanagement","volume":"156","author":"Sigal","year":"1996","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.medmal.2019.05.001_bib0755","series-title":"Diagnostics difficiles en m\u00e9decine interne","first-page":"449","article-title":"Intrications somato-psychiques: rep\u00e8res pour l\u2019interniste","author":"Cath\u00e9bras","year":"2018"},{"key":"10.1016\/j.medmal.2019.05.001_bib0760","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/j.jpsychores.2017.04.003","article-title":"A European research network to improve diagnosis, treatment and care for patients with persistent somatic symptoms: Work report of the EURONET-SOMA conference series","volume":"97","author":"Weigel","year":"2017","journal-title":"J Psychosom Res"},{"key":"10.1016\/j.medmal.2019.05.001_bib0765","series-title":"Medically unexplained symptoms, somatization and bodily distress. Developing better clinical services","first-page":"1","article-title":"Epidemiology: prevalence, causes and consequences","author":"Creed","year":"2011"},{"key":"10.1016\/j.medmal.2019.05.001_bib0770","doi-asserted-by":"crossref","first-page":"1449","DOI":"10.1136\/bmj.325.7378.1449","article-title":"What should we say to patients with symptoms unexplained by disease? The \u201cnumber needed to offend\u201d","volume":"325","author":"Stone","year":"2002","journal-title":"BMJ"},{"key":"10.1016\/j.medmal.2019.05.001_bib0775","doi-asserted-by":"crossref","DOI":"10.1002\/14651858.CD006524.pub2","article-title":"Consultation letters for medically unexplained physical symptoms in primary care","author":"Hoedeman","year":"2010","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.medmal.2019.05.001_bib0780","doi-asserted-by":"crossref","DOI":"10.1002\/14651858.CD011142","article-title":"Non-pharmacological interventions for somatoform disorders and medically unexplained physical symptoms (MUPS) in adults","author":"van Dessel","year":"2014","journal-title":"Cochrane Database Syst Rev"}],"container-title":["M\u00e9decine et Maladies Infectieuses"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0399077X19301313?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0399077X19301313?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T01:17:29Z","timestamp":1759972649000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0399077X19301313"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,8]]},"references-count":78,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2019,8]]}},"alternative-id":["S0399077X19301313"],"URL":"https:\/\/doi.org\/10.1016\/j.medmal.2019.05.001","relation":{},"ISSN":["0399-077X"],"issn-type":[{"value":"0399-077X","type":"print"}],"subject":[],"published":{"date-parts":[[2019,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Lyme borreliosis and other tick-borne diseases. Guidelines from the French scientific societies (II). Biological diagnosis, treatment, persistent symptoms after documented or suspected Lyme borreliosis","name":"articletitle","label":"Article Title"},{"value":"M\u00e9decine et Maladies Infectieuses","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.medmal.2019.05.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier Masson SAS. All rights reserved.","name":"copyright","label":"Copyright"}]}}