{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T07:17:59Z","timestamp":1760080679499,"version":"build-2065373602"},"reference-count":29,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Infectious Diseases Now"],"published-print":{"date-parts":[[2021,5]]},"DOI":"10.1016\/j.medmal.2020.10.024","type":"journal-article","created":{"date-parts":[[2020,11,1]],"date-time":"2020-11-01T23:54:17Z","timestamp":1604274857000},"page":"260-265","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Microcephaly epidemic in Brazil: An earlier chapter"],"prefix":"10.1016","volume":"51","author":[{"given":"A.","family":"Medeiros Figueiredo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Sanchez-Villegas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Cristina Moreira Marculino Figueiredo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Sousa Soares de Araujo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Daponte-Codina","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.medmal.2020.10.024_bib0150","doi-asserted-by":"crossref","first-page":"2125","DOI":"10.1016\/S0140-6736(16)00651-6","article-title":"Association between Zika virus and microcephaly in French Polynesia, 2013\u201315: a retrospective study","volume":"387","author":"Cauchemez","year":"2016","journal-title":"Lancet"},{"key":"10.1016\/j.medmal.2020.10.024_bib0155","doi-asserted-by":"crossref","first-page":"191","DOI":"10.2471\/BLT.16.178608","article-title":"Risk of microcephaly after Zika virus infection in Brazil, 2015 to 2016","volume":"95","author":"Jaenisch","year":"2017","journal-title":"Bull World Health Organ"},{"key":"10.1016\/j.medmal.2020.10.024_bib0160","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1016\/S0140-6736(17)31368-5","article-title":"Infection-related microcephaly after the 2015 and 2016 Zika virus outbreaks in Brazil: a surveillance-based analysis","volume":"390","author":"de Oliveira","year":"2017","journal-title":"Lancet"},{"key":"10.1016\/j.medmal.2020.10.024_bib0165","article-title":"Association between microcephaly, Zika virus infection, and other risk factors in Brazil: Final report of a case-control study","author":"de Ara\u00fajo","year":"2017","journal-title":"Lancet Infect Dis"},{"key":"10.1016\/j.medmal.2020.10.024_bib0170","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1016\/S0140-6736(16)30902-3","article-title":"Congenital Zika virus syndrome in Brazil: a case series of the first 1501 livebirths with complete investigation","volume":"388","author":"Fran\u00e7a","year":"2016","journal-title":"Lancet"},{"key":"10.1016\/j.medmal.2020.10.024_bib0175","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1056\/NEJMoa1600651","article-title":"Zika virus associated with microcephaly","volume":"374","author":"Mlakar","year":"2016","journal-title":"N Engl J Med"},{"key":"10.1016\/j.medmal.2020.10.024_bib0180","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1038\/nature22402","article-title":"Zika virus evolution and spread in the Americas","volume":"546","author":"Metsky","year":"2017","journal-title":"Nature"},{"key":"10.1016\/j.medmal.2020.10.024_bib0185","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1126\/science.aaf5036","article-title":"Zika virus in the Americas: early epidemiological and genetic findings","volume":"352","author":"Faria","year":"2016","journal-title":"Science"},{"key":"10.1016\/j.medmal.2020.10.024_bib0190","doi-asserted-by":"crossref","first-page":"1915","DOI":"10.1093\/infdis\/jiz396","article-title":"The impact of Zika virus emergence in French Guiana: a large general population seroprevalence survey","volume":"220","author":"Flamand","year":"2019","journal-title":"J Infect Dis"},{"key":"10.1016\/j.medmal.2020.10.024_bib0195","doi-asserted-by":"crossref","first-page":"835","DOI":"10.2471\/BLT.16.170639","article-title":"Microcephaly in north-east Brazil: a retrospective study on neonates born between 2012 and 2015","volume":"94","author":"de Ara\u00fajo","year":"2016","journal-title":"Bull World Health Organ"},{"key":"10.1016\/j.medmal.2020.10.024_bib0200","doi-asserted-by":"crossref","first-page":"1894","DOI":"10.3201\/eid2211.160901","article-title":"Increased hospitalizations for neuropathies as indicators of Zika virus infection, according to health information system data, Brazil","volume":"22","author":"Barcellos","year":"2016","journal-title":"Emerg Infect Dis"},{"volume":"30","year":"2016","author":"WHO","key":"10.1016\/j.medmal.2020.10.024_bib0205"},{"issue":"suppl 2","key":"10.1016\/j.medmal.2020.10.024_bib0210","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1111\/1471-0528.12047","article-title":"The objectives, design and implementation of the INTERGROWTH-21st project","volume":"120","author":"Villar","year":"2013","journal-title":"BJOG"},{"key":"10.1016\/j.medmal.2020.10.024_bib0215","first-page":"3","article-title":"STL: A seasonal-trend decomposition procedure based on Loess","volume":"6","author":"Cleveland","year":"1990","journal-title":"J Off Stat"},{"year":"2019","series-title":"Tidy anomaly detection","author":"Vaughan","key":"10.1016\/j.medmal.2020.10.024_bib0220"},{"year":"2016","series-title":"Technical handbook for dengue surveillance, dengue outbreak prediction\/detection and outbreak response (\u201cmodel contingency plan\u201d)","author":"WHO\/TDR","key":"10.1016\/j.medmal.2020.10.024_bib0225"},{"key":"10.1016\/j.medmal.2020.10.024_bib0230","doi-asserted-by":"crossref","first-page":"972","DOI":"10.1002\/bdra.23587","article-title":"Population-based microcephaly surveillance in the United States, 2009 to 2013: an analysis of potential sources of variation","volume":"106","author":"Cragan","year":"2016","journal-title":"Birth Defects Res A Clin Mol Teratol"},{"key":"10.1016\/j.medmal.2020.10.024_bib0235","doi-asserted-by":"crossref","DOI":"10.1016\/j.bpobgyn.2018.04.003","article-title":"The global epidemiology of preterm birth","author":"Vogel","year":"2018","journal-title":"Best Pract Res Clin Obstet Gynaecol"},{"key":"10.1016\/j.medmal.2020.10.024_bib0240","doi-asserted-by":"crossref","first-page":"1591","DOI":"10.1056\/NEJMc1608612","article-title":"Zika virus infection and associated neurologic disorders in Brazil","volume":"376","author":"de Oliveira","year":"2017","journal-title":"N Engl J Med"},{"key":"10.1016\/j.medmal.2020.10.024_bib0245","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1590\/0037-8682-0245-2016","article-title":"Zika in Pernambuco: rewriting the first outbreak","volume":"49","author":"Brito","year":"2016","journal-title":"Rev Soc Bras Med Trop"},{"key":"10.1016\/j.medmal.2020.10.024_bib0250","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1186\/s12916-015-0348-x","article-title":"Emergence and potential for spread of Chikungunya virus in Brazil","volume":"13","author":"Nunes","year":"2015","journal-title":"BMC Med"},{"key":"10.1016\/j.medmal.2020.10.024_bib0255","doi-asserted-by":"crossref","first-page":"2623","DOI":"10.1590\/S0102-311X2007001100010","article-title":"Modelagem da incid\u00eancia do dengue na Para\u00edba, Brasil, por modelos de defasagem distribu\u00edda. Cad","volume":"23","author":"Souza","year":"2007","journal-title":"Saude Publica"},{"key":"10.1016\/j.medmal.2020.10.024_bib0260","doi-asserted-by":"crossref","first-page":"242","DOI":"10.15585\/mmwr.mm6509e2","article-title":"Increase in reported prevalence of microcephaly in infants born to women living in areas with confi rmed Zika virus transmission during the fi rst trimester of pregnancy\u2013Brazil, 2015","volume":"65","author":"de Oliveira","year":"2016","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"10.1016\/j.medmal.2020.10.024_bib0265","doi-asserted-by":"crossref","first-page":"1756","DOI":"10.1590\/S0102-311X2010000900009","article-title":"Qualidade da notifica\u00e7\u00e3o de anomalies cong\u00eanitas pelo Sistema de Informa\u00e7\u00f5es sobre Nascidos Vivos (SINASC): estudo comparative nos anos 2004 e 2007","volume":"26","author":"Luquetti","year":"2010","journal-title":"Cad Saude Publica"},{"key":"10.1016\/j.medmal.2020.10.024_bib0270","doi-asserted-by":"crossref","first-page":"898","DOI":"10.1016\/S0140-6736(16)30883-2","article-title":"Pathology of congenital Zika syndrome in Brazil: a case series","volume":"388","author":"Martines","year":"2016","journal-title":"Lancet"},{"key":"10.1016\/j.medmal.2020.10.024_bib0275","first-page":"1","article-title":"Brasil Minist\u00e9rio da Sa\u00fade. Boletim Epidemiol\u00f3gico S\u00edfilis No 49","volume":"45","year":"2018"},{"key":"10.1016\/j.medmal.2020.10.024_bib0280","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0201452","article-title":"Zika might not be acting alone: using an ecological study approach to investigate potential co-acting risk factors for an unusual pattern of microcephaly in Brazil","volume":"13","author":"Campos","year":"2018","journal-title":"PLoS One"},{"key":"10.1016\/j.medmal.2020.10.024_bib0285","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1016\/S1473-3099(16)00088-8","article-title":"Dengue during pregnancy and adverse fetal outcomes: a systematic review and meta-analysis","volume":"16","author":"Paix\u00e3o","year":"2016","journal-title":"Lancet Infect Dis"},{"issue":"3","key":"10.1016\/j.medmal.2020.10.024_bib0290","doi-asserted-by":"crossref","first-page":"e1978","DOI":"10.1002\/rmv.1978","article-title":"The neurological complications of chikungunya virus: a systematic review","volume":"28","author":"Mehta","year":"2018","journal-title":"Rev Med Virol"}],"container-title":["Infectious Diseases Now"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0399077X2030771X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0399077X2030771X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T06:38:02Z","timestamp":1760078282000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0399077X2030771X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5]]},"references-count":29,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021,5]]}},"alternative-id":["S0399077X2030771X"],"URL":"https:\/\/doi.org\/10.1016\/j.medmal.2020.10.024","relation":{},"ISSN":["2666-9919"],"issn-type":[{"type":"print","value":"2666-9919"}],"subject":[],"published":{"date-parts":[[2021,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Microcephaly epidemic in Brazil: An earlier chapter","name":"articletitle","label":"Article Title"},{"value":"Infectious Diseases Now","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.medmal.2020.10.024","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Masson SAS. All rights reserved.","name":"copyright","label":"Copyright"}]}}