{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T16:03:45Z","timestamp":1761581025604},"reference-count":35,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Infection, Genetics and Evolution"],"published-print":{"date-parts":[[2013,1]]},"DOI":"10.1016\/j.meegid.2012.09.002","type":"journal-article","created":{"date-parts":[[2012,9,18]],"date-time":"2012-09-18T05:17:36Z","timestamp":1347945456000},"page":"162-167","source":"Crossref","is-referenced-by-count":10,"special_numbering":"C","title":["A variant in the promoter of MBL2 is associated with protection against visceral leishmaniasis in Morocco"],"prefix":"10.1016","volume":"13","author":[{"given":"Salsabil","family":"Hamdi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rajaa","family":"Ejghal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mouna","family":"Idrissi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sayeh","family":"Ezzikouri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammed","family":"Hida","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lynn","family":"Soong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hamid","family":"Amarouch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meryem","family":"Lemrani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.meegid.2012.09.002_b0005","doi-asserted-by":"crossref","first-page":"1212","DOI":"10.1086\/512683","article-title":"Genotypes of the mannan-binding lectin gene and susceptibility to visceral leishmaniasis and clinical complications","volume":"195","author":"Alonso","year":"2007","journal-title":"J .Infect. Dis."},{"key":"10.1016\/j.meegid.2012.09.002_b0010","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1038\/sj.gene.6364116","article-title":"Sequence analysis of the mannose-binding lectin (MBL2) gene reveals a high degree of heterozygosity with evidence of selection","volume":"5","author":"Bernig","year":"2004","journal-title":"Genes. Immun."},{"key":"10.1016\/j.meegid.2012.09.002_b0015","first-page":"183","article-title":"Anthropologic research and understanding pediatric visceral leishmaniasis in Tunisia","volume":"91","author":"Bouratbine","year":"1998","journal-title":"Bull. Soc. Pathol. Exot."},{"key":"10.1016\/j.meegid.2012.09.002_b0020","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.1007\/s10096-008-0573-8","article-title":"Low levels of mannose-binding lectin confers protection against tuberculosis in Turkish children","volume":"27","author":"Cosar","year":"2008","journal-title":"Eur. J. Clin. Microbiol. Infect. Dis."},{"key":"10.1016\/j.meegid.2012.09.002_b0025","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/S0035-9203(01)90223-8","article-title":"The increase in risk factors for leishmaniasis worldwide","volume":"95","author":"Desjeux","year":"2001","journal-title":"Trans. R. Soc. Trop. Med. Hyg."},{"key":"10.1016\/j.meegid.2012.09.002_b0030","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1111\/j.1399-0039.2006.00649.x","article-title":"Mannose-binding lectin in innate immunity: past, present and future","volume":"68","author":"Dommett","year":"2006","journal-title":"Tissue Antigens."},{"issue":"Suppl 2","key":"10.1016\/j.meegid.2012.09.002_b0035","doi-asserted-by":"crossref","first-page":"S335","DOI":"10.1086\/374746","article-title":"Role of the mannose-binding lectin in innate immunity","volume":"187","author":"Ezekowitz","year":"2003","journal-title":"J. Infect. Dis"},{"key":"10.1016\/j.meegid.2012.09.002_b0040","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1111\/j.1744-313X.1994.tb00183.x","article-title":"Dual role of mannan-binding protein in infections: Another case of heterosis? Eur","volume":"21","author":"Garred","year":"1994","journal-title":"J. Immunogenet."},{"key":"10.1016\/j.meegid.2012.09.002_b0045","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/S0161-5890(03)00104-4","article-title":"Mannose binding lectin deficiency-revisited","volume":"40","author":"Garred","year":"2003","journal-title":"Mol. Immunol."},{"key":"10.1016\/j.meegid.2012.09.002_b0050","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1038\/sj.gene.6364283","article-title":"Mannose-binding lectin and its genetic variants","volume":"7","author":"Garred","year":"2006","journal-title":"Genes. Immun."},{"key":"10.1016\/j.meegid.2012.09.002_b0055","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1111\/j.1744-313X.1992.tb00083.x","article-title":"Diallelic polymorphism may explain variations of the blood concentration of mannan-binding protein in Eskimos, but not in black Africans","volume":"19","author":"Garred","year":"1992","journal-title":"Eur. J. Immunogenet."},{"key":"10.1016\/j.meegid.2012.09.002_b0060","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1111\/j.1365-2249.1992.tb05876.x","article-title":"Gene frequency and partial protein characterization of an allelic variant of mannan binding protein associated with low serum concentrations","volume":"90","author":"Garred","year":"1992","journal-title":"Clin. Exp. Immunol."},{"issue":"298\u2013300","key":"10.1016\/j.meegid.2012.09.002_b0065","first-page":"302","article-title":"A fast method for high-quality genomic DNA extraction from whole human blood","volume":"11","author":"Gustincich","year":"1991","journal-title":"Biotechniques"},{"key":"10.1016\/j.meegid.2012.09.002_b0070","doi-asserted-by":"crossref","first-page":"28","DOI":"10.4081\/mr.2012.e7","article-title":"Socio-economic and environmental factors associated with Montenegro skin test positivity in an endemic area of visceral leishmaniasis in northern Morocco","volume":"3","author":"Hamdi","year":"2012","journal-title":"Microbiology Research."},{"key":"10.1016\/j.meegid.2012.09.002_b0075","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1016\/S0140-6736(98)10178-2","volume":"354","author":"Herwaldt","year":"1999","journal-title":"Leishmaniasis. Lancet."},{"key":"10.1016\/j.meegid.2012.09.002_b0080","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1016\/j.micinf.2007.12.008","article-title":"Mannose-binding lectin variant associated with severe malaria in young African children","volume":"10","author":"Holmberg","year":"2008","journal-title":"Microbes. Infect."},{"key":"10.1016\/j.meegid.2012.09.002_b0085","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1111\/j.1600-065X.2009.00789.x","article-title":"Mannose-binding lectin and innate immunity","volume":"230","author":"Ip","year":"2009","journal-title":"Immunol. Rev."},{"key":"10.1016\/j.meegid.2012.09.002_b0090","doi-asserted-by":"crossref","first-page":"1316","DOI":"10.1001\/jama.285.10.1316","article-title":"Acute respiratory tract infections and mannose-binding lectin insufficiency during early childhood","volume":"285","author":"Koch","year":"2001","journal-title":"Jama."},{"key":"10.1016\/j.meegid.2012.09.002_b0095","first-page":"1098","article-title":"Sequence variations in the MBL gene and their relationship to pulmonary tuberculosis in the Chinese Han population","volume":"10","author":"Liu","year":"2006","journal-title":"Int. J. of. Tuberc. Lung. Dis."},{"key":"10.1016\/j.meegid.2012.09.002_b0100","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1007\/BF00163962","article-title":"A new frequent allele is the missing link in the structural polymorphism of the human mannan-binding protein","volume":"40","author":"Madsen","year":"1994","journal-title":"Immunogenetics."},{"key":"10.1016\/j.meegid.2012.09.002_b0105","doi-asserted-by":"crossref","first-page":"3013","DOI":"10.4049\/jimmunol.155.6.3013","article-title":"Interplay between promoter and structural gene variants control basal serum level of mannan- binding protein","volume":"155","author":"Madsen","year":"1995","journal-title":"J. Immunol."},{"key":"10.1016\/j.meegid.2012.09.002_b0110","doi-asserted-by":"crossref","first-page":"3169","DOI":"10.4049\/jimmunol.161.6.3169","article-title":"Different molecular events result in low protein levels of mannan-binding lectin in populations from southeast Africa and South America","volume":"161","author":"Madsen","year":"1998","journal-title":"J. Immunol."},{"key":"10.1016\/j.meegid.2012.09.002_b0115","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/0035-9203(92)90295-N","article-title":"Leishmanin reaction in the human population of a highly endemic focus of canine leishmaniasis in Alpes-Maritimes","volume":"86","author":"Marty","year":"1992","journal-title":"France. Trans. R. Soc. Trop. Med. Hyg."},{"key":"10.1016\/j.meegid.2012.09.002_b0120","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1016\/S0198-8859(01)00237-3","article-title":"Association analysis of HLA-class II and class III gene polymorphisms in the susceptibility to mediterranean visceral leishmaniasis","volume":"62","author":"Meddeb-Garnaoui","year":"2001","journal-title":"Hum. Immunol."},{"key":"10.1016\/j.meegid.2012.09.002_b0125","first-page":"161","article-title":"Standardization of the Montenegro antigen","volume":"19","author":"Melo","year":"1977","journal-title":"Rev. Inst. Med. Trop. Sao Paulo."},{"key":"10.1016\/j.meegid.2012.09.002_b0130","first-page":"630","article-title":"Analysis of the relationship between mannose-binding lectin (MBL) genotype, MBL levels and function in an Australian blood donor population","volume":"56","author":"Minchinton","year":"2002","journal-title":"J. Immunol."},{"key":"10.1016\/j.meegid.2012.09.002_b0135","unstructured":"Ministry of Health. 2008. Rapport annuel d\u2019activit\u00e9, Maroc, Direction de l\u2019Epid\u00e9miologie et de la Lutte contre les maladies."},{"key":"10.1016\/j.meegid.2012.09.002_b0140","doi-asserted-by":"crossref","first-page":"5212","DOI":"10.1128\/IAI.69.8.5212-5215.2001","article-title":"Mannan-binding lectin enhances susceptibility to visceral leishmaniasis","volume":"69","author":"Santos","year":"2001","journal-title":"Infect. Immun."},{"key":"10.1016\/j.meegid.2012.09.002_b0145","doi-asserted-by":"crossref","first-page":"e20908","DOI":"10.1371\/journal.pone.0020908","article-title":"Variant G57E of Mannose Binding Lectin Associated with Protection against Tuberculosis Caused by Mycobacterium africanum but not by M. tuberculosis","volume":"6","author":"Thye","year":"2011","journal-title":"PLoS ONE."},{"key":"10.1016\/j.meegid.2012.09.002_b0150","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1016\/S0167-5699(96)80908-X","article-title":"Mannose-binding lectin: the pluripotent molecule of the innate immune system","volume":"17","author":"Turner","year":"1996","journal-title":"Immunol. Today."},{"key":"10.1016\/j.meegid.2012.09.002_b0155","first-page":"285","article-title":"Mutations in the human mannose binding protein gene: their frequencies in three distinct populations and relationship to serum levels of the protein","volume":"4","author":"Turner","year":"1993","journal-title":"Immunodeficiency."},{"key":"10.1016\/j.meegid.2012.09.002_b0160","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1016\/S0161-5890(03)00155-X","article-title":"The role of mannose-binding lectin in health and disease","volume":"40","author":"Turner","year":"2003","journal-title":"Mol. Immunol."},{"key":"10.1016\/j.meegid.2012.09.002_b0165","first-page":"305","article-title":"Mannose-binding lectin: structure, function, genetics and disease associations","volume":"2","author":"Turner","year":"2000","journal-title":"Rev. Immunogenet."},{"key":"10.1016\/j.meegid.2012.09.002_b0170","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/j.micpath.2004.11.002","article-title":"Immunopathogenesis of infection with the visceralizing Leishmania species","volume":"38","author":"Wilson","year":"2005","journal-title":"Microb. Pathog."},{"key":"10.1016\/j.meegid.2012.09.002_b0175","unstructured":"World Health Organisation. 2000. The Leishmaniases and Leishmania\/HIV Co-infections, Geneva."}],"container-title":["Infection, Genetics and Evolution"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567134812002936?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567134812002936?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,6,25]],"date-time":"2023-06-25T21:13:16Z","timestamp":1687727596000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1567134812002936"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,1]]},"references-count":35,"alternative-id":["S1567134812002936"],"URL":"https:\/\/doi.org\/10.1016\/j.meegid.2012.09.002","relation":{},"ISSN":["1567-1348"],"issn-type":[{"value":"1567-1348","type":"print"}],"subject":[],"published":{"date-parts":[[2013,1]]}}}