{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T08:28:27Z","timestamp":1790411307514,"version":"4.1.0"},"reference-count":40,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2013,8,1]],"date-time":"2013-08-01T00:00:00Z","timestamp":1375315200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"Research Foundation \u2013 Flanders","award":["G0552.10"],"award-info":[{"award-number":["G0552.10"]}]},{"DOI":"10.13039\/501100000781","name":"European Research Council (ERC)","doi-asserted-by":"crossref","award":["260801-BIG_IDEA"],"award-info":[{"award-number":["260801-BIG_IDEA"]}],"id":[{"id":"10.13039\/501100000781","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Infection, Genetics and Evolution"],"published-print":{"date-parts":[[2013,8]]},"DOI":"10.1016\/j.meegid.2013.05.007","type":"journal-article","created":{"date-parts":[[2013,5,14]],"date-time":"2013-05-14T20:30:20Z","timestamp":1368563420000},"page":"100-105","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":25,"special_numbering":"C","title":["Regular treatments of praziquantel do not impact on the genetic make-up of Schistosoma mansoni in Northern Senegal"],"prefix":"10.1016","volume":"18","author":[{"given":"T.","family":"Huyse","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Van den Broeck","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Jombart","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.L.","family":"Webster","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"O.","family":"Diaw","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.A.M.","family":"Volckaert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Balloux","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Rollinson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Polman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.meegid.2013.05.007_b0005","doi-asserted-by":"crossref","first-page":"1891","DOI":"10.1111\/j.0014-3820.2004.tb00477.x","article-title":"Heterozygote excess in small populations and the heterozygote-excess effective population size","volume":"58","author":"Balloux","year":"2004","journal-title":"Evolution"},{"key":"10.1016\/j.meegid.2013.05.007_b0010","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1016\/j.pt.2006.05.013","article-title":"Drug resistance and drug tolerance in parasites","volume":"22","author":"Coles","year":"2006","journal-title":"Trends Parasitol."},{"key":"10.1016\/j.meegid.2013.05.007_b0015","doi-asserted-by":"crossref","first-page":"2001","DOI":"10.1093\/genetics\/144.4.2001","article-title":"Description and power analysis of two tests for detecting recent population bottlenecks from allele frequency data","volume":"144","author":"Cornuet","year":"1996","journal-title":"Genetics"},{"key":"10.1016\/j.meegid.2013.05.007_b0020","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/S1471-4922(01)02209-7","article-title":"Interpreting low praziquantel cure rates of Schistosoma mansoni infections in Senegal","volume":"18","author":"Danso-Appiah","year":"2002","journal-title":"Trends Parasitol."},{"key":"10.1016\/j.meegid.2013.05.007_b0025","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1046\/j.1365-3156.1999.00444.x","article-title":"The epidemiology of a recent focus of mixed Schistoroma haematobium and Schistosoma mansoni infections around the \u2018Lac de Guiers\u2019 in the Senegal River Basin, Senegal","volume":"4","author":"De Clercq","year":"1999","journal-title":"Trop. Med. Int. Health"},{"key":"10.1016\/j.meegid.2013.05.007_b0030","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1016\/S0035-9203(02)90405-0","article-title":"Resistance of Schistosoma mansoni to praziquantel: is there a problem?","volume":"96","author":"Doenhoff","year":"2002","journal-title":"Trans. R. Soc. Trop. Med. Hyg."},{"key":"10.1016\/j.meegid.2013.05.007_b0035","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/S0001-706X(99)00013-3","article-title":"Increase of intestinal schistosomiasis after praziquantel treatment in a Schistosoma haematobium and Schistosoma mansoni mixed focus","volume":"73","author":"Ernould","year":"1999","journal-title":"Acta Trop."},{"key":"10.1016\/j.meegid.2013.05.007_b0040","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1017\/S003118200006460X","article-title":"Efficacy of treatment of murine Schistosoma mansoni infections with praziquantel and oxamniquine correlates with infection intensity \u2013 role of host antibody","volume":"111","author":"Fallon","year":"1995","journal-title":"Parasitology"},{"key":"10.1016\/j.meegid.2013.05.007_b0045","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1006\/expr.1997.4149","article-title":"Schistosoma mansoni: maturation rate and drug susceptibility of different geographic isolates","volume":"86","author":"Fallon","year":"1997","journal-title":"Exp. Parasitol."},{"key":"10.1016\/j.meegid.2013.05.007_b0050","unstructured":"Goudet, J., 2001. FSTAT, a program to estimate and test gene diversities and fixation indices (version 2.9.3). Available from: <http:\/\/www.unil.ch\/izea\/softwares\/fstat.html>."},{"key":"10.1016\/j.meegid.2013.05.007_b0055","first-page":"209","article-title":"Epidemiology, immunology and chemotherapy of Schistosoma mansoni infections in a recently exposed community in Senegal","volume":"46","author":"Gryseels","year":"1994","journal-title":"Trop. Geogr. Med."},{"key":"10.1016\/j.meegid.2013.05.007_b0060","doi-asserted-by":"crossref","first-page":"864","DOI":"10.1046\/j.1365-3156.2001.00811.x","article-title":"Are poor responses to praziquantel for the treatment of Schistosoma mansoni infections in Senegal due to resistance? An overview of the evidence","volume":"6","author":"Gryseels","year":"2001","journal-title":"Trop. Med. Int. Health"},{"key":"10.1016\/j.meegid.2013.05.007_b0065","doi-asserted-by":"crossref","first-page":"1106","DOI":"10.1016\/S0140-6736(06)69440-3","article-title":"Human schistosomiasis","volume":"368","author":"Gryseels","year":"2006","journal-title":"Lancet"},{"key":"10.1016\/j.meegid.2013.05.007_b0070","doi-asserted-by":"crossref","first-page":"e412","DOI":"10.1371\/journal.pntd.0000412","article-title":"Neglected tropical diseases in sub-Saharan Africa: review of their prevalence, distribution, and disease burden","volume":"3","author":"Hotez","year":"2009","journal-title":"Plos Negl. Trop. Dis."},{"key":"10.1016\/j.meegid.2013.05.007_b0075","doi-asserted-by":"crossref","first-page":"e1000571","DOI":"10.1371\/journal.ppat.1000571","article-title":"Bidirectional introgressive hybridization between a cattle and human schistosome species","volume":"5","author":"Huyse","year":"2009","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.meegid.2013.05.007_b0080","doi-asserted-by":"crossref","first-page":"1403","DOI":"10.1093\/bioinformatics\/btn129","article-title":"Adegenet: a R package for the multivariate analysis of genetic markers","volume":"24","author":"Jombart","year":"2008","journal-title":"Bioinformatics"},{"key":"10.1016\/j.meegid.2013.05.007_b0085","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1186\/1471-2156-11-94","article-title":"Discriminant analysis of principal components: a new method for the analysis of genetically structured populations","volume":"11","author":"Jombart","year":"2010","journal-title":"BMC Genet."},{"key":"10.1016\/j.meegid.2013.05.007_b0090","first-page":"397","article-title":"A simple device for quantitative stool thick-smear technique in schistosomiasis mansoni","volume":"14","author":"Katz","year":"1972","journal-title":"Rev. I. Med. Trop."},{"key":"10.1016\/j.meegid.2013.05.007_b0095","doi-asserted-by":"crossref","first-page":"e1321","DOI":"10.1371\/journal.pntd.0001321","article-title":"Utility of repeated praziquantel dosing in the treatment of schistosomiasis in high-risk communities in Africa: a systematic review","volume":"5","author":"King","year":"2011","journal-title":"Plos. Neg. Trop. Dis."},{"key":"10.1016\/j.meegid.2013.05.007_b0100","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/j.ijpara.2012.02.002","article-title":"Epidemiology of mixed Schistosoma mansoni and Schistosoma haematobium infections in Northern Senegal","volume":"42","author":"Meurs","year":"2012","journal-title":"Int. J. Parasitol."},{"key":"10.1016\/j.meegid.2013.05.007_b0105","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1016\/j.trstmh.2011.04.003","article-title":"Cure rate is not a valid indicator for assessing drug efficacy and impact of preventive chemotherapy interventions against schistosomiasis and soil-transmitted helminthiasis","volume":"105","author":"Montresor","year":"2011","journal-title":"Trans. R. Soc. Trop. Med. Hyg."},{"key":"10.1016\/j.meegid.2013.05.007_b0110","doi-asserted-by":"crossref","first-page":"951","DOI":"10.4269\/ajtmh.2010.10-0283","article-title":"Genetic consequences of mass human chemotherapy for Schistosoma mansoni: population structure pre- and post-praziquantel treatment in Tanzania","volume":"83","author":"Norton","year":"2010","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"10.1016\/j.meegid.2013.05.007_b0115","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1016\/S0035-9203(96)90501-5","article-title":"The epidemiology of human schistosomiasis in the Senegal river basin","volume":"90","author":"Picquet","year":"1996","journal-title":"T. Roy. Soc. Trop. Med. H."},{"key":"10.1016\/j.meegid.2013.05.007_b0120","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/S0035-9203(98)90971-3","article-title":"Efficacy of praziquantel against Schistosoma mansoni in northern Senegal","volume":"92","author":"Picquet","year":"1998","journal-title":"T. Roy. Soc. Trop. Med. H."},{"key":"10.1016\/j.meegid.2013.05.007_b0125","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1016\/0035-9203(75)90126-1","article-title":"Simple and rapid technique for quantitative estimation of helminth eggs in human and animal excreta with special reference to Schistosoma sp","volume":"69","author":"Pitchford","year":"1975","journal-title":"T. Roy. Soc. Trop. Med. H."},{"key":"10.1016\/j.meegid.2013.05.007_b0130","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1179\/000349802125001708","article-title":"Evaluation of the patterns of Schistosoma mansoni infection and re-infection in Senegal, from faecal egg counts and serum concentrations of circulating anodic antigen","volume":"96","author":"Polman","year":"2002","journal-title":"Ann. Trop. Med. Parasitol."},{"key":"10.1016\/j.meegid.2013.05.007_b0135","doi-asserted-by":"crossref","first-page":"1355","DOI":"10.1111\/j.1365-294X.2005.02541.x","article-title":"F-statistics under alternation of sexual and asexual reproduction: a model and data from schistosomes (platyhelminth parasites)","volume":"14","author":"Prugnolle","year":"2005","journal-title":"Mol. Ecol."},{"key":"10.1016\/j.meegid.2013.05.007_b0140","series-title":"R: A Language and Environment for Statistical Computing","author":"R Development Core Team","year":"2011"},{"key":"10.1016\/j.meegid.2013.05.007_b0145","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1016\/S0169-4758(98)01310-6","article-title":"An international initiative on praziquantel use","volume":"14","author":"Renganathan","year":"1998","journal-title":"Parasitol. Today"},{"key":"10.1016\/j.meegid.2013.05.007_b0150","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1016\/0014-4894(86)90184-0","article-title":"Schistosoma mansoni \u2013 chemotherapy of infections of different ages","volume":"61","author":"Sabah","year":"1986","journal-title":"Exp. Parasitol."},{"key":"10.1016\/j.meegid.2013.05.007_b0155","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.parint.2004.01.001","article-title":"Progress in the prevention and control of schistosomiasis and soil-transmitted helminthiasis","volume":"53","author":"Savioli","year":"2004","journal-title":"Parasitol. Int."},{"key":"10.1016\/j.meegid.2013.05.007_b0160","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1016\/S0020-7519(98)00021-6","article-title":"Recent studies on the reproductive biology of the schistosomes and their relevance to speciation in the Digenea","volume":"28","author":"Southgate","year":"1998","journal-title":"Int. J. Parasitol."},{"key":"10.1016\/j.meegid.2013.05.007_b0165","doi-asserted-by":"crossref","first-page":"167","DOI":"10.4269\/ajtmh.1995.53.167","article-title":"Efficacy and side-effects of praziquantel in an epidemic focus of Schistosoma mansoni","volume":"53","author":"Stelma","year":"1995","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"10.1016\/j.meegid.2013.05.007_b0170","first-page":"173","article-title":"Outbreak of intestinal schistosomiasis in the Senegal River Basin","volume":"70","author":"Talla","year":"1990","journal-title":"Ann. Soc. Belg. Med. Tr."},{"key":"10.1016\/j.meegid.2013.05.007_b0175","doi-asserted-by":"crossref","first-page":"1413","DOI":"10.1016\/j.meegid.2011.05.006","article-title":"Optimal sample storage and extraction procotols for reliable multilocus genotyping of the human parasite Schistosoma mansoni","volume":"11","author":"Van den Broeck","year":"2011","journal-title":"Infect. Genet. Evol."},{"key":"10.1016\/j.meegid.2013.05.007_b0180","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1111\/j.1471-8286.2004.00684.x","article-title":"MICRO-CHECKER: software for identifying and correcting genotyping errors in microsatellite data","volume":"4","author":"Van Oosterhout","year":"2004","journal-title":"Mol. Ecol. Notes"},{"key":"10.1016\/j.meegid.2013.05.007_b0185","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1016\/0035-9203(94)90400-6","article-title":"Preliminary study of urinary schistosomiasis in a village in the delta of the Senegal River Basin, Senegal","volume":"88","author":"Verle","year":"1994","journal-title":"T. Roy. Soc. Trop. Med. H."},{"key":"10.1016\/j.meegid.2013.05.007_b0190","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1017\/S0022149X99000591","article-title":"Mating interactions between Schistosoma haematobium and S. mansoni","volume":"73","author":"Webster","year":"1999","journal-title":"J. Helminthol."},{"key":"10.1016\/j.meegid.2013.05.007_b0195","unstructured":"Webster, B.L., Diaw, O.T., Seye, M.M., Faye, D.S., Stothard, J.R., Figueiredo, J.C.S., Rollinson, D., in press. Impact of praziquantel treatment on human schistosomiasis in Senegal River Basin: monitoring the efficacy of cure and re-infection patterns at mixed (Schistosoma mansoni & S. haematobium) and single (S. haematobium) infection foci. Acta Trop."},{"key":"10.1016\/j.meegid.2013.05.007_b0200","doi-asserted-by":"crossref","first-page":"1358","DOI":"10.2307\/2408641","article-title":"Estimating F-statistics for the analysis of population-structure","volume":"38","author":"Weir","year":"1984","journal-title":"Evolution"}],"container-title":["Infection, Genetics and Evolution"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567134813001925?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567134813001925?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,2,16]],"date-time":"2022-02-16T20:51:22Z","timestamp":1645044682000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1567134813001925"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,8]]},"references-count":40,"alternative-id":["S1567134813001925"],"URL":"https:\/\/doi.org\/10.1016\/j.meegid.2013.05.007","relation":{},"ISSN":["1567-1348"],"issn-type":[{"value":"1567-1348","type":"print"}],"subject":[],"published":{"date-parts":[[2013,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Regular treatments of praziquantel do not impact on the genetic make-up of Schistosoma mansoni in Northern Senegal","name":"articletitle","label":"Article Title"},{"value":"Infection, Genetics and Evolution","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.meegid.2013.05.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}