{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T06:18:56Z","timestamp":1770704336870,"version":"3.49.0"},"reference-count":24,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2014,3,1]],"date-time":"2014-03-01T00:00:00Z","timestamp":1393632000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Infection, Genetics and Evolution"],"published-print":{"date-parts":[[2014,3]]},"DOI":"10.1016\/j.meegid.2013.09.020","type":"journal-article","created":{"date-parts":[[2013,9,27]],"date-time":"2013-09-27T18:34:17Z","timestamp":1380306857000},"page":"201-207","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":21,"special_numbering":"C","title":["Exploring the effect of dentition, dental decay and familiality on oral health using metabolomics"],"prefix":"10.1016","volume":"22","author":[{"given":"Betsy","family":"Foxman","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Usha","family":"Srinivasan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ai","family":"Wen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lixin","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carl F.","family":"Marrs","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deborah","family":"Goldberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Weyant","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"McNeil","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard","family":"Crout","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mary","family":"Marazita","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.meegid.2013.09.020_b0005","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1177\/0022034509341967","article-title":"Acceleration of purine degradation by periodontal diseases","volume":"88","author":"Barnes","year":"2009","journal-title":"J. Dent. Res."},{"key":"10.1016\/j.meegid.2013.09.020_b0010","doi-asserted-by":"crossref","first-page":"352","DOI":"10.4161\/gmic.21215","article-title":"Microbial ecology and host\u2013microbiota interactions during early life stages","volume":"3","author":"Collado","year":"2012","journal-title":"Gut Microbes"},{"issue":"16","key":"10.1016\/j.meegid.2013.09.020_b0015","doi-asserted-by":"crossref","first-page":"6656","DOI":"10.1021\/ac901536h","article-title":"Integrated, nontargeted ultrahigh performance liquid chromatography\/electrospray ionization tandem mass spectrometry platform for the identification and relative quantification of the small-molecule complement of biological systems","volume":"81","author":"Evans","year":"2009","journal-title":"Anal. Chem."},{"key":"10.1016\/j.meegid.2013.09.020_b0020","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1089\/omi.2011.0035","article-title":"Metabolomics reveals differential levels of oral metabolites in HIV-infected patients: toward novel diagnostic targets","volume":"17","author":"Ghannoum","year":"2011","journal-title":"OMICS"},{"issue":"107\u2013109","key":"10.1016\/j.meegid.2013.09.020_b0025","first-page":"112","article-title":"Salivary biomarkers for caries risk assessment","volume":"41","author":"Guo","year":"2013","journal-title":"J. California Dent. Assoc."},{"key":"10.1016\/j.meegid.2013.09.020_b0030","doi-asserted-by":"crossref","first-page":"1130","DOI":"10.1177\/0022034512461652","article-title":"Factors associated with alkali production from arginine in dental biofilms","volume":"91","author":"Huang","year":"2012","journal-title":"J. Dent. Res."},{"key":"10.1016\/j.meegid.2013.09.020_b0035","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/j.coi.2011.03.001","article-title":"Regulation of innate and adaptive immunity by the commensal microbiota","volume":"23","author":"Jarchum","year":"2011","journal-title":"Curr. Opin. Immunol."},{"key":"10.1016\/j.meegid.2013.09.020_b0040","doi-asserted-by":"crossref","first-page":"383","DOI":"10.2217\/14622416.9.4.383","article-title":"Analysis of the adult human plasma metabolome","volume":"9","author":"Lawton","year":"2008","journal-title":"Pharmacogenomics"},{"key":"10.1016\/j.meegid.2013.09.020_b0045","doi-asserted-by":"crossref","first-page":"e37919","DOI":"10.1371\/journal.pone.0037919","volume":"7","author":"Liu","year":"2012","journal-title":"PLoS ONE"},{"key":"10.1016\/j.meegid.2013.09.020_b0050","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1007\/BF01569822","article-title":"Dental plaque as a biofilm","volume":"15","author":"Marsh","year":"1995","journal-title":"J. Ind. Microbiol."},{"key":"10.1016\/j.meegid.2013.09.020_b0055","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1111\/j.1399-302X.2008.00477.x","article-title":"Correlations of oral bacterial arginine and urea catabolism with caries experience","volume":"24","author":"Nascimento","year":"2009","journal-title":"Oral Microbiol. Immunol."},{"key":"10.1016\/j.meegid.2013.09.020_b0060","unstructured":"Oksanen, J., Blanchet, G., Kindt, R., Legendre, P., Minchin, P., O\u2019Hara, R.B.O., Simpson, G., Solymos, P., Stevens, M.H.H., Wagner, H., 2013. vegan: community ecology package version 2.0-7. http:\/\/cran.r-project.org\/web\/packages\/vegan\/index.html."},{"key":"10.1016\/j.meegid.2013.09.020_b0065","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1186\/1472-6831-8-18","volume":"8","author":"Polk","year":"2008","journal-title":"BMC Oral Health"},{"key":"10.1016\/j.meegid.2013.09.020_b0070","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1111\/j.1574-6941.2007.00375.x","article-title":"Multivariate analyses in microbial ecology","volume":"62","author":"Ramette","year":"2007","journal-title":"FEMS Microbiol. Ecol."},{"key":"10.1016\/j.meegid.2013.09.020_b0075","volume":"346","author":"Sedgwick","year":"2013","journal-title":"BMJ"},{"key":"10.1016\/j.meegid.2013.09.020_b0080","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1177\/0022034512463579","article-title":"GWAS of dental caries patterns in the permanent dentition","volume":"92","author":"Shaffer","year":"2013","journal-title":"J. Dent. Res."},{"key":"10.1016\/j.meegid.2013.09.020_b0085","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1159\/000016462","article-title":"Dental caries susceptibility in mice is closely linked to the H-2 region on chromosome 17","volume":"32","author":"Suzuki","year":"1998","journal-title":"Caries Res."},{"key":"10.1016\/j.meegid.2013.09.020_b0090","unstructured":"Suzuki, R., Shimodaira, H., 2011. pvclust: hierarchical clustering with P-values via multiscale bootstrap resampling. http:\/\/cran.r-project.org\/web\/packages\/pvclust\/index.html."},{"key":"10.1016\/j.meegid.2013.09.020_b0095","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1177\/0022034510379602","article-title":"The role of bacteria in the caries process: ecological perspectives","volume":"90","author":"Takahashi","year":"2011","journal-title":"J. Dent. Res."},{"issue":"2","key":"10.1016\/j.meegid.2013.09.020_b0100","doi-asserted-by":"crossref","first-page":"115","DOI":"10.5650\/jos.57.115","article-title":"Lipids in human parotid saliva with regard to caries experience","volume":"57","author":"Tomita","year":"2008","journal-title":"J. Oleo Sci."},{"key":"10.1016\/j.meegid.2013.09.020_b0105","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1111\/j.1365-263X.2006.00733.x","article-title":"Total antioxidant levels of saliva in children related to caries, age, and gender","volume":"16","author":"Tulunoglu","year":"2006","journal-title":"Int. J. Pediatr. Dent."},{"key":"10.1016\/j.meegid.2013.09.020_b0110","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1177\/00220345950740021001","article-title":"Association of free arginine and lysine concentrations in human parotid saliva with caries experience","volume":"74","author":"VanWuyckhuyse","year":"1995","journal-title":"J. Dent. Res."},{"key":"10.1016\/j.meegid.2013.09.020_b0115","first-page":"71","article-title":"Basic amino acid in the pathogenesis of caries","volume":"25","author":"Vranic","year":"1991","journal-title":"Acta Stomatologica Croatica"},{"key":"10.1016\/j.meegid.2013.09.020_b0120","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1177\/0022034513481976","article-title":"Genome-wide association studies of pit-and-fissure- and smooth-surface caries in permanent dentition","volume":"92","author":"Zeng","year":"2013","journal-title":"J. Dent. Res."}],"container-title":["Infection, Genetics and Evolution"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567134813003614?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567134813003614?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,10,12]],"date-time":"2018-10-12T12:54:15Z","timestamp":1539348855000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1567134813003614"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,3]]},"references-count":24,"alternative-id":["S1567134813003614"],"URL":"https:\/\/doi.org\/10.1016\/j.meegid.2013.09.020","relation":{},"ISSN":["1567-1348"],"issn-type":[{"value":"1567-1348","type":"print"}],"subject":[],"published":{"date-parts":[[2014,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Exploring the effect of dentition, dental decay and familiality on oral health using metabolomics","name":"articletitle","label":"Article Title"},{"value":"Infection, Genetics and Evolution","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.meegid.2013.09.020","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}