{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T06:03:35Z","timestamp":1763705015659,"version":"3.37.3"},"reference-count":36,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2015,3,1]],"date-time":"2015-03-01T00:00:00Z","timestamp":1425168000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81273133"],"award-info":[{"award-number":["81273133"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Infection, Genetics and Evolution"],"published-print":{"date-parts":[[2015,3]]},"DOI":"10.1016\/j.meegid.2014.12.036","type":"journal-article","created":{"date-parts":[[2015,1,6]],"date-time":"2015-01-06T12:36:24Z","timestamp":1420547784000},"page":"238-243","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"special_numbering":"C","title":["Scrub typhus caused by Orientia tsutsugamushi Kawasaki-related genotypes in Shandong Province, northern China"],"prefix":"10.1016","volume":"30","author":[{"given":"Luyan","family":"Zhang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhenwang","family":"Bi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zengqiang","family":"Kou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huili","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aihua","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shoufeng","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiangpeng","family":"Meng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meng","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hui","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhongtang","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.meegid.2014.12.036_b0010","first-page":"31","article-title":"PCR amplification and phylogenetic analysis of the partial gene segment of 56kDa protein of Orientia tsutsugamushi from the first case of scrub typhus in Hefei city","volume":"20","author":"Cao","year":"2013","journal-title":"Acta Parasitol. Med. Entomol. Sin."},{"key":"10.1016\/j.meegid.2014.12.036_b0015","first-page":"275","article-title":"Investigation of scrub typhus in Shanxi Province and study on its etiology","volume":"24","author":"Chen","year":"2000","journal-title":"Bull. Acad. Mil. Med. Sci."},{"key":"10.1016\/j.meegid.2014.12.036_b0020","first-page":"2","article-title":"Outbreak of scrub typhus in Shanxi Province","volume":"12","author":"Chen","year":"1996","journal-title":"Chin. J. Zoonoses"},{"key":"10.1016\/j.meegid.2014.12.036_b0025","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1258\/td.2010.090452","article-title":"Scrub typhus: an unrecognized threat in South India \u2013 clinical profile and predictors of mortality","volume":"40","author":"Chrispal","year":"2010","journal-title":"Trop. Doct."},{"key":"10.1016\/j.meegid.2014.12.036_b0030","first-page":"358","article-title":"Epidemiological investigation on an outbreak of autumn tsutsugamushi disease in Taizhou region of Jiangsu Province","volume":"31","author":"Chu","year":"2013","journal-title":"Chin. J. Infect. Dis."},{"key":"10.1016\/j.meegid.2014.12.036_b0035","doi-asserted-by":"crossref","DOI":"10.1136\/bcr-2013-201849","article-title":"Pancreatitis in scrub typhus: a rare complication","volume":"2014","author":"Dhakal","year":"2014","journal-title":"BMJ Case Rep."},{"key":"10.1016\/j.meegid.2014.12.036_b0040","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1111\/j.1574-6968.1999.tb08791.x","article-title":"Phylogenetic analysis of Orientia tsutsugamushi strains based on the sequence homologies of 56-kDa type-specific antigen genes","volume":"180","author":"Enatsu","year":"1999","journal-title":"FEMS Microbiol. Lett."},{"key":"10.1016\/j.meegid.2014.12.036_b0045","doi-asserted-by":"crossref","first-page":"1637","DOI":"10.1128\/JCM.31.6.1637-1640.1993","article-title":"Serotype-specific amplification of Rickettsia tsutsugamushi DNA by nested polymerase chain reaction","volume":"31","author":"Furuya","year":"1993","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.meegid.2014.12.036_b0050","first-page":"28","article-title":"Investigation of Orientia tsutsugamushi serotype in Fujian","volume":"6","author":"He","year":"2000","journal-title":"Strait J. Prev. Med."},{"key":"10.1016\/j.meegid.2014.12.036_b0055","first-page":"1079","article-title":"Epidemiological study of scrub typhus disease in Yancheng city during 2006 to 2010","volume":"27","author":"Jiang","year":"2011","journal-title":"J. Med. Pest Control"},{"issue":"Suppl. 3","key":"10.1016\/j.meegid.2014.12.036_b0060","doi-asserted-by":"crossref","first-page":"S203","DOI":"10.1086\/596576","article-title":"Scrub typhus: the geographic distribution of phenotypic and genotypic variants of Orientia tsutsugamushi","volume":"48","author":"Kelly","year":"2009","journal-title":"Clin. Infect. Dis."},{"key":"10.1016\/j.meegid.2014.12.036_b0065","doi-asserted-by":"crossref","first-page":"1206","DOI":"10.4269\/ajtmh.13-0224","article-title":"Scrub typhus meningitis or meningoencephalitis","volume":"89","author":"Kim","year":"2013","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"10.1016\/j.meegid.2014.12.036_b0070","doi-asserted-by":"crossref","first-page":"1548","DOI":"10.1128\/JCM.01040-07","article-title":"Acute renal failure due to acute tubular necrosis caused by direct invasion of Orientia tsutsugamushi","volume":"46","author":"Kim","year":"2008","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.meegid.2014.12.036_b0075","doi-asserted-by":"crossref","first-page":"1296","DOI":"10.1086\/508464","article-title":"Clinical usefulness of eschar polymerase chain reaction for the diagnosis of scrub typhus: a prospective study","volume":"43","author":"Kim","year":"2006","journal-title":"Clin. Infect. Dis."},{"key":"10.1016\/j.meegid.2014.12.036_b0080","doi-asserted-by":"crossref","first-page":"e22731","DOI":"10.1371\/journal.pone.0022731","article-title":"Differences in clinical features according to Boryong and Karp genotypes of Orientia tsutsugamushi","volume":"6","author":"Kim","year":"2011","journal-title":"PLoS ONE"},{"key":"10.1016\/j.meegid.2014.12.036_b0085","doi-asserted-by":"crossref","first-page":"1169","DOI":"10.1128\/JCM.44.3.1169-1171.2006","article-title":"Usefulness of eschar PCR for diagnosis of scrub typhus","volume":"44","author":"Lee","year":"2006","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.meegid.2014.12.036_b0090","doi-asserted-by":"crossref","first-page":"123","DOI":"10.4269\/ajtmh.12-0728","article-title":"Laboratory diagnosis and genotype identification of scrub typhus from Pinggu district, Beijing, 2008 and 2010","volume":"89","author":"Li","year":"2013","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"10.1016\/j.meegid.2014.12.036_b0095","article-title":"Clinical diagnosis and therapy of 24 adult patients with tsutsugamushi disease","volume":"32","author":"Liu","year":"2014","journal-title":"Chin. J. Infect. Dis."},{"key":"10.1016\/j.meegid.2014.12.036_b0100","first-page":"698","article-title":"Amplification and typing of Sta56 gene of Orientia tsutsugamushi from Shandong Province","volume":"25","author":"Liu","year":"2004","journal-title":"Chin. J. Epidemiol."},{"key":"10.1016\/j.meegid.2014.12.036_b0105","first-page":"353","article-title":"Characterization of Orientia tsutsugamushi strains isolated in Shandong Province, China by immunofluorescence and restriction fragment length polymorphism (RFLP) analyses","volume":"35","author":"Liu","year":"2004","journal-title":"Southeast Asian J. Trop. Med. Public Health"},{"key":"10.1016\/j.meegid.2014.12.036_b0110","doi-asserted-by":"crossref","first-page":"658","DOI":"10.4269\/ajtmh.2010.09-0608","article-title":"Phylogenetic analysis of 56-kDa type-specific antigen gene of Orientia tsutsugamushi isolates in Taiwan","volume":"83","author":"Lu","year":"2010","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"10.1016\/j.meegid.2014.12.036_b0115","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1093\/dnares\/dsq018","article-title":"Genome comparison and phylogenetic analysis of Orientia tsutsugamushi strains","volume":"17","author":"Nakayama","year":"2010","journal-title":"DNA Res."},{"key":"10.1016\/j.meegid.2014.12.036_b0120","doi-asserted-by":"crossref","first-page":"12728","DOI":"10.1016\/S0021-9258(18)42337-X","article-title":"Diversity of immunodominant 56-kDa type-specific antigen (TSA) of Rickettsia tsutsugamushi. Sequence and comparative analyses of the genes encoding TSA homologues from four antigenic variants","volume":"267","author":"Ohashi","year":"1992","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.meegid.2014.12.036_b0125","doi-asserted-by":"crossref","first-page":"e6","DOI":"10.1086\/498747","article-title":"Acute hearing loss due to scrub typhus: a forgotten complication of a reemerging disease","volume":"42","author":"Premaratna","year":"2005","journal-title":"Clin. Infect. Dis."},{"key":"10.1016\/j.meegid.2014.12.036_b0130","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1016\/j.trstmh.2003.10.011","article-title":"Paediatric scrub typhus in Thailand: a study of 73 confirmed cases","volume":"98","author":"Silpapojakul","year":"2004","journal-title":"Trans. R. Soc. Trop. Med. Hyg."},{"key":"10.1016\/j.meegid.2014.12.036_b0135","first-page":"769","article-title":"Molecular epidemiological study of the outbreak of scrub typhus disease in Jiangsu area in 2011","volume":"32","author":"Tan","year":"2012","journal-title":"Chin. J. Microbiol. Immunol."},{"key":"10.1016\/j.meegid.2014.12.036_b0140","first-page":"240","article-title":"Serious complications in scrub typhus","volume":"31","author":"Tsay","year":"1998","journal-title":"J. Microbiol. Immunol. Infect."},{"key":"10.1016\/j.meegid.2014.12.036_b0145","doi-asserted-by":"crossref","first-page":"1148","DOI":"10.4269\/ajtmh.2007.76.1148","article-title":"Acute respiratory distress syndrome in scrub typhus","volume":"76","author":"Wang","year":"2007","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"10.1016\/j.meegid.2014.12.036_b0150","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1097\/00001432-200310000-00009","article-title":"Scrub typhus and tropical rickettsioses","volume":"16","author":"Watt","year":"2003","journal-title":"Curr. Opin. Infect. Dis."},{"key":"10.1016\/j.meegid.2014.12.036_b0155","doi-asserted-by":"crossref","first-page":"e46997","DOI":"10.1371\/journal.pone.0046997","article-title":"New genotypes of Orientia tsutsugamushi isolated from humans in Eastern Taiwan","volume":"7","author":"Yang","year":"2012","journal-title":"PLoS ONE"},{"key":"10.1016\/j.meegid.2014.12.036_b0160","doi-asserted-by":"crossref","first-page":"968","DOI":"10.4269\/ajtmh.2008.78.968","article-title":"Comparative analysis of nucleotide sequences of Orientia tsutsugamushi in different epidemic areas of scrub typhus in Shandong, China","volume":"78","author":"Yang","year":"2008","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"10.1016\/j.meegid.2014.12.036_b0165","first-page":"482","article-title":"Follow-up analysis on the epidemic strains of Orientia tsutsugamushi in the first outbreak of scrub typhus in Henan Province, China","volume":"38","author":"Zhang","year":"2007","journal-title":"Southeast Asian J. Trop. Med. Public Health"},{"key":"10.1016\/j.meegid.2014.12.036_b0170","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.4269\/ajtmh.2012.12-0306","article-title":"Scrub typhus: surveillance, clinical profile and diagnostic issues in Shandong, China","volume":"87","author":"Zhang","year":"2012","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"10.1016\/j.meegid.2014.12.036_b0175","first-page":"475","article-title":"Investigation on rodents\u2019 natural infection of Orientia tsutsugamushi in some areas of Inner Mongolia and Xinjiang, China","volume":"27","author":"Zhang","year":"2006","journal-title":"Zhonghua Liu Xing Bing Xue Za Zhi"},{"key":"10.1016\/j.meegid.2014.12.036_b0180","doi-asserted-by":"crossref","first-page":"1241","DOI":"10.1128\/JCM.01784-09","article-title":"Scrub typhus in previously unrecognized areas of endemicity in China","volume":"48","author":"Zhang","year":"2010","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.meegid.2014.12.036_b0185","first-page":"641","article-title":"Clinical features of tsutsugamushi disease among children and adults in north of Guangdong Province","volume":"19","author":"Zhou","year":"2006","journal-title":"Acta Med. Sinica"}],"container-title":["Infection, Genetics and Evolution"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567134814004924?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567134814004924?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,4,26]],"date-time":"2022-04-26T01:42:24Z","timestamp":1650937344000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1567134814004924"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,3]]},"references-count":36,"alternative-id":["S1567134814004924"],"URL":"https:\/\/doi.org\/10.1016\/j.meegid.2014.12.036","relation":{},"ISSN":["1567-1348"],"issn-type":[{"type":"print","value":"1567-1348"}],"subject":[],"published":{"date-parts":[[2015,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Scrub typhus caused by Orientia tsutsugamushi Kawasaki-related genotypes in Shandong Province, northern China","name":"articletitle","label":"Article Title"},{"value":"Infection, Genetics and Evolution","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.meegid.2014.12.036","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}