{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T14:14:39Z","timestamp":1789913679015,"version":"4.0.1"},"reference-count":56,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2015,4,1]],"date-time":"2015-04-01T00:00:00Z","timestamp":1427846400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"Ministry of Science and Technology","award":["BT\/PR15173\/GBD\/27\/356\/2011"],"award-info":[{"award-number":["BT\/PR15173\/GBD\/27\/356\/2011"]}]},{"DOI":"10.13039\/501100001412","name":"Council of Scientific and Industrial Research","doi-asserted-by":"publisher","award":["37(1542)\/12\/EMR-II"],"award-info":[{"award-number":["37(1542)\/12\/EMR-II"]}],"id":[{"id":"10.13039\/501100001412","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Infection, Genetics and Evolution"],"published-print":{"date-parts":[[2015,4]]},"DOI":"10.1016\/j.meegid.2015.01.017","type":"journal-article","created":{"date-parts":[[2015,1,31]],"date-time":"2015-01-31T05:21:16Z","timestamp":1422681676000},"page":"118-126","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":19,"special_numbering":"C","title":["In silico analysis of MHC-I restricted epitopes of Chikungunya virus proteins: Implication in understanding anti-CHIKV CD8+ T cell response and advancement of epitope based immunotherapy for CHIKV infection"],"prefix":"10.1016","volume":"31","author":[{"given":"B.M.","family":"Pratheek","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amol R.","family":"Suryawanshi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8378-1014","authenticated-orcid":false,"given":"Soma","family":"Chattopadhyay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Subhasis","family":"Chattopadhyay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.meegid.2015.01.017_b0005","series-title":"Discovery Studio Visualizer","author":"Accelrys-Software-Inc.","year":"2013"},{"key":"10.1016\/j.meegid.2015.01.017_b0010","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1016\/S0952-7915(06)80037-3","article-title":"Synthetic peptides as vaccines","volume":"4","author":"Arnon","year":"1992","journal-title":"Curr. Opin. Immunol."},{"key":"10.1016\/j.meegid.2015.01.017_b0015","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1089\/vim.2012.0061","article-title":"Nonstructural protein 2 (nsP2) of Chikungunya virus (CHIKV) enhances protective immunity mediated by a CHIKV envelope protein expressing DNA Vaccine","volume":"26","author":"Bao","year":"2013","journal-title":"Viral Immunol."},{"issue":"Pt 2","key":"10.1016\/j.meegid.2015.01.017_b0020","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1099\/0022-1317-77-2-315","article-title":"The JHM strain of mouse hepatitis virus induces a spike protein-specific Db-restricted cytotoxic T cell response","volume":"77","author":"Bergmann","year":"1996","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.meegid.2015.01.017_b0025","doi-asserted-by":"crossref","first-page":"1022","DOI":"10.1016\/0264-410X(92)90111-V","article-title":"New approaches to vaccination against foot-and-mouth disease","volume":"10","author":"Brown","year":"1992","journal-title":"Vaccine"},{"key":"10.1016\/j.meegid.2015.01.017_b0030","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1016\/S0198-8859(01)00298-1","article-title":"Analysis of the frequencies of HLA-A, B, and C alleles and haplotypes in the five major ethnic groups of the United States reveals high levels of diversity in these loci and contrasting distribution patterns in these populations","volume":"62","author":"Cao","year":"2001","journal-title":"Hum. Immunol."},{"key":"10.1016\/j.meegid.2015.01.017_b0035","doi-asserted-by":"crossref","first-page":"884","DOI":"10.1016\/j.humimm.2005.06.002","article-title":"Continuous presence of Th1 conditions is necessary for longer lasting tumor-specific CTL activity in stimulation cultures with PBL","volume":"66","author":"Chattopadhyay","year":"2005","journal-title":"Hum. Immunol."},{"key":"10.1016\/j.meegid.2015.01.017_b0040","doi-asserted-by":"crossref","first-page":"984","DOI":"10.4049\/jimmunol.176.2.984","article-title":"Effect of CD4+ CD25+ and CD4+ CD25\u2212 T regulatory cells on the generation of cytolytic T cell response to a self but human tumor-associated epitope in vitro","volume":"176","author":"Chattopadhyay","year":"2006","journal-title":"J. Immunol."},{"key":"10.1016\/j.meegid.2015.01.017_b0045","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/j.jviromet.2013.10.015","article-title":"Characterisation of mouse monoclonal antibodies targeting linear epitopes on Chikungunya virus E2 glycoprotein","volume":"195","author":"Chua","year":"2014","journal-title":"J. Virol. Methods"},{"key":"10.1016\/j.meegid.2015.01.017_b0050","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1002\/prot.21795","article-title":"ClusPro: performance in CAPRI rounds 6\u201311 and the new server","volume":"69","author":"Comeau","year":"2007","journal-title":"Proteins"},{"key":"10.1016\/j.meegid.2015.01.017_b0055","doi-asserted-by":"crossref","first-page":"1188","DOI":"10.1101\/gr.849004","article-title":"WebLogo: a sequence logo generator","volume":"14","author":"Crooks","year":"2004","journal-title":"Genome Res."},{"key":"10.1016\/j.meegid.2015.01.017_b0060","doi-asserted-by":"crossref","first-page":"5361","DOI":"10.1128\/JVI.71.7.5361-5365.1997","article-title":"Theiler\u2019s virus and Mengo virus induce cross-reactive cytotoxic T lymphocytes restricted to the same immunodominant VP2 epitope in C57BL\/6 mice","volume":"71","author":"Dethlefs","year":"1997","journal-title":"J. Virol."},{"key":"10.1016\/j.meegid.2015.01.017_b0065","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/0022-2836(84)90309-7","article-title":"Analysis of membrane and surface protein sequences with the hydrophobic moment plot","volume":"179","author":"Eisenberg","year":"1984","journal-title":"J. Mol. Biol."},{"key":"10.1016\/j.meegid.2015.01.017_b0070","doi-asserted-by":"crossref","first-page":"4453","DOI":"10.1016\/j.vaccine.2005.03.044","article-title":"Co-immunization of BALB\/c mice with recombinant immunogens containing G protein fragment and chimeric CTL epitope of respiratory syncytial virus induces enhanced cellular immunity and high level of antibody response","volume":"23","author":"Fan","year":"2005","journal-title":"Vaccine"},{"key":"10.1016\/j.meegid.2015.01.017_b0075","doi-asserted-by":"crossref","first-page":"2869","DOI":"10.1016\/j.vaccine.2004.11.066","article-title":"Fusion of DsbA to the N-terminus of CTL chimeric epitope, F\/M2:81\u201395, of respiratory syncytial virus prolongs protein- and virus-specific CTL responses in Balb\/c mice","volume":"23","author":"Fan","year":"2005","journal-title":"Vaccine"},{"key":"10.1016\/j.meegid.2015.01.017_b0080","doi-asserted-by":"crossref","first-page":"4840","DOI":"10.4049\/jimmunol.169.9.4840","article-title":"High-affinity HLA-A(*)02.01 peptides from parathyroid hormone-related protein generate in vitro and in vivo antitumor CTL response without autoimmune side effects","volume":"169","author":"Francini","year":"2002","journal-title":"J. Immunol."},{"key":"10.1016\/j.meegid.2015.01.017_b0085","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S0031-6865(99)00005-9","article-title":"Peptides and polypeptides as modulators of the immune response: thymopentin \u2013 an example with unknown mode of action","volume":"73","author":"Gonser","year":"1999","journal-title":"Pharm. Acta Helv."},{"key":"10.1016\/j.meegid.2015.01.017_b0090","series-title":"Fields Virology","first-page":"1023","article-title":"Alphaviruses","author":"Griffin","year":"2007"},{"key":"10.1016\/j.meegid.2015.01.017_b0095","doi-asserted-by":"crossref","first-page":"2858","DOI":"10.1128\/JVI.03453-13","article-title":"Novel attenuated Chikungunya vaccine candidates elicit protective immunity in C57BL\/6 mice","volume":"88","author":"Hallengard","year":"2014","journal-title":"J. Virol."},{"key":"10.1016\/j.meegid.2015.01.017_b0100","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1038\/nri2575","article-title":"MHC class I antigen presentation: learning from viral evasion strategies","volume":"9","author":"Hansen","year":"2009","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.meegid.2015.01.017_b0110","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1002\/jmv.20164","article-title":"Major histocompatibility complex class-I presentation impaired in transgenic mice expressing hepatitis C virus structural proteins during dendritic cell maturation","volume":"74","author":"Hiasa","year":"2004","journal-title":"J. Med. Virol."},{"key":"10.1016\/j.meegid.2015.01.017_b0115","doi-asserted-by":"crossref","first-page":"e84695","DOI":"10.1371\/journal.pone.0084695","article-title":"Identical strength of the T cell responses against E2, nsP1 and capsid CHIKV proteins in recovered and chronic patients after the epidemics of 2005\u20132006 in La Reunion Island","volume":"8","author":"Hoarau","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.meegid.2015.01.017_b0120","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s00251-008-0341-z","article-title":"NetMHCpan, a method for MHC class I binding prediction beyond humans","volume":"61","author":"Hoof","year":"2009","journal-title":"Immunogenetics"},{"key":"10.1016\/j.meegid.2015.01.017_b0125","doi-asserted-by":"crossref","first-page":"W525","DOI":"10.1093\/nar\/gks438","article-title":"Immune epitope database analysis resource","volume":"40","author":"Kim","year":"2012","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.meegid.2015.01.017_b0130","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1186\/1471-2105-10-394","article-title":"Derivation of an amino acid similarity matrix for peptide: MHC binding and its application as a Bayesian prior","volume":"10","author":"Kim","year":"2009","journal-title":"BMC Bioinform."},{"key":"10.1016\/j.meegid.2015.01.017_b0135","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1002\/prot.21117","article-title":"PIPER: an FFT-based protein docking program with pairwise potentials","volume":"65","author":"Kozakov","year":"2006","journal-title":"Proteins"},{"key":"10.1016\/j.meegid.2015.01.017_b0140","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1186\/1743-422X-9-313","article-title":"Mouse macrophage innate immune response to Chikungunya virus infection","volume":"9","author":"Kumar","year":"2012","journal-title":"Virol. J."},{"key":"10.1016\/j.meegid.2015.01.017_b0145","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.virol.2008.04.043","article-title":"Comprehensive analysis of T cell epitope discovery strategies using 17DD yellow fever virus structural proteins and BALB\/c (H2d) mice model","volume":"378","author":"Maciel","year":"2008","journal-title":"Virology"},{"key":"10.1016\/j.meegid.2015.01.017_b0150","doi-asserted-by":"crossref","first-page":"6092","DOI":"10.1016\/j.vaccine.2013.09.045","article-title":"Chikungunya virus-like particles are more immunogenic in a lethal AG129 mouse model compared to glycoprotein E1 or E2 subunits","volume":"31","author":"Metz","year":"2013","journal-title":"Vaccine"},{"key":"10.1016\/j.meegid.2015.01.017_b0155","doi-asserted-by":"crossref","first-page":"888","DOI":"10.1002\/jcc.540130714","article-title":"Validation of the general purpose QUANTA 3.2\/CHARMm force field","volume":"13","author":"Momany","year":"1992","journal-title":"J. Comput. Chem."},{"key":"10.1016\/j.meegid.2015.01.017_b0160","doi-asserted-by":"crossref","first-page":"7530","DOI":"10.1016\/j.vaccine.2007.08.044","article-title":"Computational analysis of proteome of H5N1 avian influenza virus to define T cell epitopes with vaccine potential","volume":"25","author":"Parida","year":"2007","journal-title":"Vaccine"},{"key":"10.1016\/j.meegid.2015.01.017_b0165","doi-asserted-by":"crossref","first-page":"163","DOI":"10.4049\/jimmunol.152.1.163","article-title":"Scheme for ranking potential HLA-A2 binding peptides based on independent binding of individual peptide side-chains","volume":"152","author":"Parker","year":"1994","journal-title":"J. Immunol."},{"key":"10.1016\/j.meegid.2015.01.017_b0170","doi-asserted-by":"crossref","first-page":"1493","DOI":"10.3201\/eid1210.060610","article-title":"Novel Chikungunya virus variant in travelers returning from Indian Ocean islands","volume":"12","author":"Parola","year":"2006","journal-title":"Emerg. Infect. Dis."},{"key":"10.1016\/j.meegid.2015.01.017_b0175","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1006\/viro.1998.9576","article-title":"Immune response to the immunodominant epitope of mouse hepatitis virus is polyclonal, but functionally monospecific in C57Bl\/6 mice","volume":"255","author":"Pewe","year":"1999","journal-title":"Virology"},{"key":"10.1016\/j.meegid.2015.01.017_b0180","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s13337-013-0130-7","article-title":"Immune regulation and evasion of Mammalian host cell immunity during viral infection","volume":"24","author":"Pratheek","year":"2013","journal-title":"Indian J. Virol."},{"key":"10.1016\/j.meegid.2015.01.017_b0185","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1007\/s002510050595","article-title":"SYFPEITHI: database for MHC ligands and peptide motifs","volume":"50","author":"Rammensee","year":"1999","journal-title":"Immunogenetics"},{"key":"10.1016\/j.meegid.2015.01.017_b0190","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1007\/s00251-004-0709-7","article-title":"Enhancement to the RANKPEP resource for the prediction of peptide binding to MHC molecules using profiles","volume":"56","author":"Reche","year":"2004","journal-title":"Immunogenetics"},{"key":"10.1016\/j.meegid.2015.01.017_b0195","doi-asserted-by":"crossref","first-page":"W138","DOI":"10.1093\/nar\/gki357","article-title":"PEPVAC: a web server for multi-epitope vaccine development based on the prediction of supertypic MHC ligands","volume":"33","author":"Reche","year":"2005","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.meegid.2015.01.017_b0200","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/S0168-1702(00)00219-7","article-title":"Induction of CTL responses and identification of a novel epitope of hepatitis B virus surface antigens in C57BL\/6 mice immunized with recombinant vaccinia viruses","volume":"73","author":"Roh","year":"2001","journal-title":"Virus Res."},{"key":"10.1016\/j.meegid.2015.01.017_b0205","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1017\/S0022172400044454","article-title":"A laboratory technique for studying the insect transmission of animal viruses, employing a bat-wing membrane, demonstrated with two African viruses","volume":"54","author":"Ross","year":"1956","journal-title":"J. Hyg. (Lond)"},{"key":"10.1016\/j.meegid.2015.01.017_b0210","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.meegid.2013.04.037","article-title":"Genetic characterization of E2 region of Chikungunya virus circulating in Odisha, Eastern India from 2010 to 2011","volume":"18","author":"Sahu","year":"2013","journal-title":"Infect Genet. Evol."},{"key":"10.1016\/j.meegid.2015.01.017_b0215","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.virusres.2010.07.014","article-title":"Immunogenicity of novel Dengue virus epitopes identified by bioinformatic analysis","volume":"153","author":"Sanchez-Burgos","year":"2010","journal-title":"Virus Res."},{"key":"10.1016\/j.meegid.2015.01.017_b0220","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/S0198-8859(96)00138-3","article-title":"Minimal phenotype panels. A method for achieving maximum population coverage with a minimum of HLA antigens","volume":"51","author":"Schipper","year":"1996","journal-title":"Hum. Immunol."},{"key":"10.1016\/j.meegid.2015.01.017_b0225","unstructured":"Schr\u00f6dinger, L., 2010 The PyMOL molecular graphics system, Version 1.3r1, Version 1.3r1 ed."},{"key":"10.1016\/j.meegid.2015.01.017_b0230","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1016\/S0952-7915(03)00083-9","article-title":"Epitope-based vaccines: an update on epitope identification, vaccine design and delivery","volume":"15","author":"Sette","year":"2003","journal-title":"Curr. Opin. Immunol."},{"key":"10.1016\/j.meegid.2015.01.017_b0235","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1186\/1743-422X-8-55","article-title":"Promiscuous prediction and conservancy analysis of CTL binding epitopes of HCV 3a viral proteome from Punjab Pakistan: an in silico approach","volume":"8","author":"Shehzadi","year":"2011","journal-title":"Virol. J."},{"key":"10.1016\/j.meegid.2015.01.017_b0240","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1007\/s11262-009-0411-9","article-title":"Genetic characterization of 2006\u20132008 isolates of Chikungunya virus from Kerala, South India, by whole genome sequence analysis","volume":"40","author":"Sreekumar","year":"2010","journal-title":"Virus Genes"},{"key":"10.1016\/j.meegid.2015.01.017_b0245","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1128\/MMBR.58.3.491-562.1994","article-title":"The Alphaviruses: gene expression, replication, and evolution","volume":"58","author":"Strauss","year":"1994","journal-title":"Microbiol. Rev."},{"issue":"Suppl. 2","key":"10.1016\/j.meegid.2015.01.017_b0250","doi-asserted-by":"crossref","first-page":"S21","DOI":"10.1186\/1471-2105-14-S2-S21","article-title":"Molecular docking analysis of 2009\u2013H1N1 and 2004\u2013H5N1 influenza virus HLA-B*4405-restricted HA epitope candidates: implications for TCR cross-recognition and vaccine development","volume":"14","author":"Su","year":"2013","journal-title":"BMC Bioinform."},{"key":"10.1016\/j.meegid.2015.01.017_b0255","doi-asserted-by":"crossref","first-page":"2731","DOI":"10.1093\/molbev\/msr121","article-title":"MEGA5: molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods","volume":"28","author":"Tamura","year":"2011","journal-title":"Mol. Biol. Evol."},{"key":"10.1016\/j.meegid.2015.01.017_b0260","doi-asserted-by":"crossref","first-page":"e9291","DOI":"10.1371\/journal.pone.0009291","article-title":"HLA class I restriction as a possible driving force for Chikungunya evolution","volume":"5","author":"Tong","year":"2010","journal-title":"PLoS ONE"},{"key":"10.1016\/j.meegid.2015.01.017_b0265","doi-asserted-by":"crossref","first-page":"942","DOI":"10.1093\/bioinformatics\/btm061","article-title":"POPI: predicting immunogenicity of MHC class I binding peptides by mining informative physicochemical properties","volume":"23","author":"Tung","year":"2007","journal-title":"Bioinformatics"},{"key":"10.1016\/j.meegid.2015.01.017_b0270","doi-asserted-by":"crossref","first-page":"1737","DOI":"10.1099\/0022-1317-82-7-1737","article-title":"Naked RNA immunization with replicons derived from poliovirus and Semliki Forest virus genomes for the generation of a cytotoxic T cell response against the influenza A virus nucleoprotein","volume":"82","author":"Vignuzzi","year":"2001","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.meegid.2015.01.017_b0275","doi-asserted-by":"crossref","first-page":"7619","DOI":"10.1128\/JVI.73.9.7619-7626.1999","article-title":"The cytotoxic T-cell response to herpes simplex virus type 1 infection of C57BL\/6 mice is almost entirely directed against a single immunodominant determinant","volume":"73","author":"Wallace","year":"1999","journal-title":"J. Virol."},{"key":"10.1016\/j.meegid.2015.01.017_b0280","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1093\/infdis\/jiq006","article-title":"The acute phase of Chikungunya virus infection in humans is associated with strong innate immunity and T CD8 cell activation","volume":"204","author":"Wauquier","year":"2011","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.meegid.2015.01.017_b0285","doi-asserted-by":"crossref","first-page":"2660","DOI":"10.1128\/JVI.75.6.2660-2664.2001","article-title":"Protection from Ebola virus mediated by cytotoxic T lymphocytes specific for the viral nucleoprotein","volume":"75","author":"Wilson","year":"2001","journal-title":"J. Virol."}],"container-title":["Infection, Genetics and Evolution"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567134815000301?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567134815000301?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,8,2]],"date-time":"2023-08-02T10:59:19Z","timestamp":1690973959000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1567134815000301"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,4]]},"references-count":56,"alternative-id":["S1567134815000301"],"URL":"https:\/\/doi.org\/10.1016\/j.meegid.2015.01.017","relation":{},"ISSN":["1567-1348"],"issn-type":[{"value":"1567-1348","type":"print"}],"subject":[],"published":{"date-parts":[[2015,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"In silico analysis of MHC-I restricted epitopes of Chikungunya virus proteins: Implication in understanding anti-CHIKV CD8+ T cell response and advancement of epitope based immunotherapy for CHIKV infection","name":"articletitle","label":"Article Title"},{"value":"Infection, Genetics and Evolution","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.meegid.2015.01.017","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}