{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T10:20:47Z","timestamp":1789813247343,"version":"4.0.1"},"reference-count":33,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2015,12,1]],"date-time":"2015-12-01T00:00:00Z","timestamp":1448928000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"Ministry of Health & Welfare, Republic of Korea","award":["HI14C0257"],"award-info":[{"award-number":["HI14C0257"]}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Infection, Genetics and Evolution"],"published-print":{"date-parts":[[2015,12]]},"DOI":"10.1016\/j.meegid.2015.09.001","type":"journal-article","created":{"date-parts":[[2015,9,2]],"date-time":"2015-09-02T22:57:51Z","timestamp":1441234671000},"page":"1-7","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":29,"special_numbering":"C","title":["Genetic basis of antimicrobial resistance and clonal dynamics of carbapenem-resistant  Acinetobacter baumannii  sequence type 191 in a Korean hospital"],"prefix":"10.1016","volume":"36","author":[{"given":"Gati Noble","family":"Selasi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asiimwe","family":"Nicholas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyejin","family":"Jeon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoo Chul","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeong Rae","family":"Yoo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sang Taek","family":"Heo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Je Chul","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.meegid.2015.09.001_bb0005","doi-asserted-by":"crossref","first-page":"1477","DOI":"10.1107\/S174430911204571X","article-title":"Structure determination of LpxA from the lipopolysaccharide-synthesis pathway of Acinetobacter baumannii","volume":"68","author":"Badger","year":"2012","journal-title":"Acta Crystallogr. Sect. F: Struct. Biol. Cryst. Commun."},{"key":"10.1016\/j.meegid.2015.09.001_bb0010","doi-asserted-by":"crossref","first-page":"4382","DOI":"10.1128\/JCM.43.9.4382-4390.2005","article-title":"Development of a multilocus sequence typing scheme for characterization of clinical isolates of Acinetobacter baumannii","volume":"43","author":"Bartual","year":"2005","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.meegid.2015.09.001_bb0015","doi-asserted-by":"crossref","first-page":"3370","DOI":"10.1128\/AAC.00079-11","article-title":"Phosphoethanolamine modification of lipid A in colistin-resistant variants of Acinetobacter baumannii mediated by the pmrAB two-component regulatory system","volume":"55","author":"Beceiro","year":"2011","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.meegid.2015.09.001_bb0020","doi-asserted-by":"crossref","first-page":"1419","DOI":"10.1128\/JCM.06276-11","article-title":"Phenotypic, biochemical, and molecular techniques for detection of metallo-\u03b2-lactamase NDM in Acinetobacter baumannii","volume":"50","author":"Bonnin","year":"2012","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.meegid.2015.09.001_bb0025","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/j.jmii.2011.01.017","article-title":"Predictors of mortality in surgical patients with Acinetobacter baumannii bacteremia","volume":"44","author":"Chen","year":"2011","journal-title":"J. Microbiol. Immunol. Infect."},{"key":"10.1016\/j.meegid.2015.09.001_bb0030","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.diagmicrobio.2009.02.010","article-title":"Genetic basis of resistance to aminoglycosides in Acinetobacter spp. and spread of armA in Acinetobacter baumannii sequence group 1 in Korean hospitals","volume":"64","author":"Cho","year":"2009","journal-title":"Diagn. Microbiol. Infect. Dis."},{"key":"10.1016\/j.meegid.2015.09.001_bb0035","series-title":"Performance standards for antimicrobial susceptibility testing; twenty-first informational supplement. Document M100-S21","author":"Clinical and Laboratory Standards Institute","year":"2011"},{"key":"10.1016\/j.meegid.2015.09.001_bb0040","doi-asserted-by":"crossref","first-page":"e10034","DOI":"10.1371\/journal.pone.0010034","article-title":"The population structure of Acinetobacter baumannii: expanding multi-resistant clones from an ancestral susceptible genetic pool","volume":"5","author":"Diancourt","year":"2010","journal-title":"PLoS One"},{"key":"10.1016\/j.meegid.2015.09.001_bb0045","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1038\/nrmicro1789","article-title":"An increasing threat in hospitals: multidrug-resistant Acinetobacter baumannii","volume":"5","author":"Dijkshoorn","year":"2007","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.meegid.2015.09.001_bb0050","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.1086\/429323","article-title":"Colistin: the revival of polymyxins for the management of multidrug-resistant gram-negative bacterial infections","volume":"40","author":"Falagas","year":"2005","journal-title":"Clin. Infect. Dis."},{"key":"10.1016\/j.meegid.2015.09.001_bb0055","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.meegid.2013.07.016","article-title":"Emergency and spread of carbapenem resistant Acinetobacter baumannii sequence type 191 in a Korean hospital","volume":"19","author":"Gurung","year":"2013","journal-title":"Infect. Genet. Evol."},{"key":"10.1016\/j.meegid.2015.09.001_bb0060","doi-asserted-by":"crossref","first-page":"3198","DOI":"10.1128\/AAC.49.8.3198-3202.2005","article-title":"Contribution of acquired carbapenem-hydrolyzing oxacillinases to carbapenem resistance in Acinetobacter baumannii","volume":"49","author":"H\u00e9ritier","year":"2005","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.meegid.2015.09.001_bb0065","doi-asserted-by":"crossref","first-page":"e115452","DOI":"10.1371\/journal.pone.0115452","article-title":"Molecular epidemiology of carbapenem non-susceptible Acinetobacter baumannii in France","volume":"9","author":"Jeannot","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.meegid.2015.09.001_bb0070","doi-asserted-by":"crossref","first-page":"2241","DOI":"10.1128\/JCM.43.5.2241-2245.2005","article-title":"Investigation of a nosocomial outbreak of imipenem-resistant Acinetobacter baumannii producing the OXA-23 \u03b2-lactamase in Korea","volume":"43","author":"Jeon","year":"2005","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.meegid.2015.09.001_bb0075","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1089\/mdr.2014.0234","article-title":"Molecular epidemiology and mechanisms of carbapenem resistance of Acinetobacter spp. in Asia and Oceania","volume":"21","author":"Kamolvit","year":"2015","journal-title":"Microb. Drug Resist."},{"key":"10.1016\/j.meegid.2015.09.001_bb0080","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1093\/jac\/dkm007","article-title":"Differences in phenotypic and genotypic traits against antimicrobial agents between Acinetobacter baumannii and Acinetobacter genospecies 13TU","volume":"59","author":"Lee","year":"2007","journal-title":"J. Antimicrob. Chemother."},{"key":"10.1016\/j.meegid.2015.09.001_bb0085","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1093\/jac\/dkq402","article-title":"Carbapenem-non-susceptible Acinetobacter baumannii of sequence type 92 or its single-locus variants with a G428T substitution in zone 2 of the rpoB gene","volume":"66","author":"Lee","year":"2011","journal-title":"J. Antimicrob. Chemother."},{"key":"10.1016\/j.meegid.2015.09.001_bb0090","doi-asserted-by":"crossref","first-page":"2078","DOI":"10.1128\/AAC.01398-09","article-title":"Genetic basis of multidrug resistance in Acinetobacter clinical isolates in Taiwan","volume":"54","author":"Lin","year":"2010","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.meegid.2015.09.001_bb0095","doi-asserted-by":"crossref","first-page":"S37","DOI":"10.1016\/S0924-8579(12)70008-0","article-title":"Epidemiology and antimicrobial susceptibility profiles of Gram-negative bacteria causing urinary tract infections in the Asia\u2013Pacific region: 2009\u20132010 results from the Study for Monitoring Antimicrobial Resistance Trends (SMART)","volume":"40","author":"Lu","year":"2012","journal-title":"Int. J. Antimicrob. Agents"},{"key":"10.1016\/j.meegid.2015.09.001_bb0100","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1111\/j.1469-0691.2011.03570.x","article-title":"Multidrug-resistant, extensively drug-resistant and pandrug-resistant bacteria: an international expert proposal for interim standard definitions for acquired resistance","volume":"18","author":"Magiorakos","year":"2012","journal-title":"Clin. Microbiol. Infect."},{"key":"10.1016\/j.meegid.2015.09.001_bb0105","doi-asserted-by":"crossref","first-page":"4971","DOI":"10.1128\/AAC.00834-10","article-title":"Colistin resistance in Acinetobacter baumannii is mediated by complete loss of lipopolysaccharide production","volume":"54","author":"Moffatt","year":"2010","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.meegid.2015.09.001_bb0110","doi-asserted-by":"crossref","first-page":"35","DOI":"10.3201\/eid1601.090852","article-title":"Worldwide dissemination of the blaOXA\u221223 carbapenemase gene of Acinetobacter baumannii","volume":"16","author":"Mugnier","year":"2010","journal-title":"Emerg. Infect. Dis."},{"key":"10.1016\/j.meegid.2015.09.001_bb0115","doi-asserted-by":"crossref","first-page":"3628","DOI":"10.1128\/AAC.00284-09","article-title":"Resistance to colistin in Acinetobacter baumannii associated with mutations in the PmrAB two-component system","volume":"53","author":"Nickel","year":"2009","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.meegid.2015.09.001_bb0130","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1089\/mdr.2009.0088","article-title":"A single clone of Acinetobacter baumannii, ST22, is responsible for high antimicrobial resistance rates of Acinetobacter spp. isolates that cause bacteremia and urinary tract infections in Korea","volume":"16","author":"Park","year":"2010","journal-title":"Microb. Drug Resist."},{"key":"10.1016\/j.meegid.2015.09.001_bb0120","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1016\/j.ijantimicag.2011.02.008","article-title":"Correlation between overexpression and amino acid substitution of the PmrAB locus and colistin resistance in Acinetobacter baumannii","volume":"37","author":"Park","year":"2011","journal-title":"Int. J. Antimicrob. Agents"},{"key":"10.1016\/j.meegid.2015.09.001_bb0125","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1099\/jmm.0.033852-0","article-title":"Changes in antimicrobial susceptibility and major clones of Acinetobacter calcoaceticus-baumannii complex isolates from a single hospital in Korea over 7years","volume":"61","author":"Park","year":"2012","journal-title":"J. Med. Microbiol."},{"key":"10.1016\/j.meegid.2015.09.001_bb0135","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1093\/jac\/dkl441","article-title":"Acinetobacter baumannii bloodstream infection while receiving tigecycline: a cautionary report","volume":"59","author":"Peleg","year":"2007","journal-title":"J. Antimicrob. Chemother."},{"key":"10.1016\/j.meegid.2015.09.001_bb0140","series-title":"Tygacil\u00ae Product Insert","author":"Pfizer Inc. (Wyeth Pharmaceuticals Inc.)","year":"2014"},{"key":"10.1016\/j.meegid.2015.09.001_bb0145","doi-asserted-by":"crossref","first-page":"1708","DOI":"10.1128\/AAC.49.5.1708-1713.2005","article-title":"Genetic environment and expression of the extended-spectrum \u03b2-lactamase blaPER\u22121 gene in gram-negative bacteria","volume":"49","author":"Poirel","year":"2005","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.meegid.2015.09.001_bb0150","doi-asserted-by":"crossref","first-page":"1106","DOI":"10.1128\/JCM.01877-07","article-title":"Characterization of genetic diversity of carbapenem-resistant Acinetobacter baumannii clinical strains collected from 2004 to 2007","volume":"46","author":"Qi","year":"2008","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.meegid.2015.09.001_bb0155","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/j.ijantimicag.2011.10.015","article-title":"Comparative activity of carbapenem testing (COMPACT) study in Germany","volume":"39","author":"Valenza","year":"2012","journal-title":"Int. J. Antimicrob. Agents"},{"key":"10.1016\/j.meegid.2015.09.001_bb0160","doi-asserted-by":"crossref","first-page":"1884","DOI":"10.1128\/AAC.50.5.1884-1886.2006","article-title":"Increasing prevalence and diversity of metallo-\u03b2-lactamases in Pseudomonas spp., Acinetobacter spp., and Enterobacteriaceae from Korea","volume":"50","author":"Yong","year":"2006","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.meegid.2015.09.001_bb0165","doi-asserted-by":"crossref","first-page":"84","DOI":"10.3947\/ic.2014.46.2.84","article-title":"Increase in the prevalence of carbapenem-resistant Acinetobacter isolates and ampicillin-resistant non-typhoidal Salmonella species in Korea: a KONSAR study conducted in 2011","volume":"46","author":"Yong","year":"2014","journal-title":"Infect. Chemother."}],"container-title":["Infection, Genetics and Evolution"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567134815003688?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567134815003688?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,7,16]],"date-time":"2018-07-16T10:45:39Z","timestamp":1531737939000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1567134815003688"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,12]]},"references-count":33,"alternative-id":["S1567134815003688"],"URL":"https:\/\/doi.org\/10.1016\/j.meegid.2015.09.001","relation":{},"ISSN":["1567-1348"],"issn-type":[{"value":"1567-1348","type":"print"}],"subject":[],"published":{"date-parts":[[2015,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Genetic basis of antimicrobial resistance and clonal dynamics of carbapenem-resistant Acinetobacter baumannii sequence type 191 in a Korean hospital","name":"articletitle","label":"Article Title"},{"value":"Infection, Genetics and Evolution","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.meegid.2015.09.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}