{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T18:55:50Z","timestamp":1760122550866,"version":"3.40.5"},"reference-count":36,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,10,1]],"date-time":"2016-10-01T00:00:00Z","timestamp":1475280000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"Council of Scientific & Industrial Research","award":["OSDD\/HCP001\/12FYP\/2012-2013\/FIN\/2408"],"award-info":[{"award-number":["OSDD\/HCP001\/12FYP\/2012-2013\/FIN\/2408"]}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Infection, Genetics and Evolution"],"published-print":{"date-parts":[[2016,10]]},"DOI":"10.1016\/j.meegid.2016.07.004","type":"journal-article","created":{"date-parts":[[2016,7,5]],"date-time":"2016-07-05T03:45:57Z","timestamp":1467690357000},"page":"182-189","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"special_numbering":"C","title":["Predicting promiscuous antigenic T cell epitopes of Mycobacterium tuberculosis mymA operon proteins binding to MHC Class I and Class II molecules"],"prefix":"10.1016","volume":"44","author":[{"given":"Iti","family":"Saraav","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kirti","family":"Pandey","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Monika","family":"Sharma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Swati","family":"Singh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Prasun","family":"Dutta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anshu","family":"Bhardwaj","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2851-4770","authenticated-orcid":false,"given":"Sadhna","family":"Sharma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.meegid.2016.07.004_bb0005","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1086\/381689","article-title":"Human leukocyte antigen class I supertypes influence susceptibility and severity of tuberculosis","volume":"189","author":"Balamurugan","year":"2004","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.meegid.2016.07.004_bb0010","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/S1472-9792(02)00089-6","article-title":"Structure, function, and biogenesis of the cell wall of Mycobacterium tuberculosis","volume":"83","author":"Brennan","year":"2003","journal-title":"Tuberculosis (Edinb)"},{"key":"10.1016\/j.meegid.2016.07.004_bb0015","doi-asserted-by":"crossref","first-page":"1265","DOI":"10.1016\/j.vaccine.2004.08.046","article-title":"Defining putative T cell epitopes from PE and PPE families of proteins of Mycobacterium tuberculosis with vaccine potential","volume":"23","author":"Chaitra","year":"2005","journal-title":"Vaccine"},{"key":"10.1016\/j.meegid.2016.07.004_bb0020","doi-asserted-by":"crossref","first-page":"12210","DOI":"10.1073\/pnas.210391497","article-title":"Antimicrobial activity of MHC class I-restricted CD8+ T cells in human tuberculosis","volume":"97","author":"Cho","year":"2000","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.meegid.2016.07.004_bb0025","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1046\/j.1440-1711.2002.01092.x","article-title":"Immuno-informatics: mining genomes for vaccine components","volume":"80","author":"De Groot","year":"2002","journal-title":"Immunol. Cell Biol."},{"key":"10.1016\/j.meegid.2016.07.004_bb0030","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1186\/1471-2105-8-4","article-title":"VaxiJen: a server for prediction of protective antigens, tumour antigens and subunit vaccines","volume":"8","author":"Doytchinova","year":"2007","journal-title":"BMC Bioinforma."},{"key":"10.1016\/j.meegid.2016.07.004_bb0035","doi-asserted-by":"crossref","first-page":"411","DOI":"10.3389\/fimmu.2012.00411","article-title":"The granuloma in tuberculosis: dynamics of a host-pathogen collusion","volume":"3","author":"Ehlers","year":"2013","journal-title":"Front. Immunol."},{"key":"10.1016\/j.meegid.2016.07.004_bb0040","doi-asserted-by":"crossref","first-page":"4025","DOI":"10.1128\/JB.184.14.4025-4032.2002","article-title":"Microarray analysis of the Mycobacterium tuberculosis transcriptional response to the acidic conditions found in phagosomes","volume":"184","author":"Fisher","year":"2002","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.meegid.2016.07.004_bb0045","doi-asserted-by":"crossref","first-page":"2419","DOI":"10.1002\/eji.200737365","article-title":"Extensive HLA class I allele promiscuity among viral CTL epitopes","volume":"37","author":"Frahm","year":"2007","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.meegid.2016.07.004_bb0050","doi-asserted-by":"crossref","first-page":"256","DOI":"10.3389\/fimmu.2014.00256","article-title":"Innovative strategies to identify M. tuberculosis antigens and epitopes using genome-wide analyses","volume":"5","author":"Geluk","year":"2014","journal-title":"Front. Immunol."},{"key":"10.1016\/j.meegid.2016.07.004_bb0055","doi-asserted-by":"crossref","first-page":"524","DOI":"10.3389\/fimmu.2014.00524","article-title":"Significance of antigen and epitope specificity in tuberculosis","volume":"5","author":"Ivanyi","year":"2014","journal-title":"Front. Immunol."},{"key":"10.1016\/j.meegid.2016.07.004_bb0060","doi-asserted-by":"crossref","first-page":"13938","DOI":"10.1371\/journal.pone.0013938","article-title":"Portrait of a pathogen: the Mycobacterium tuberculosis proteome in vivo","volume":"5","author":"Kruh","year":"2010","journal-title":"PLoS One"},{"key":"10.1016\/j.meegid.2016.07.004_bb0065","doi-asserted-by":"crossref","first-page":"11090","DOI":"10.1074\/jbc.M808705200","article-title":"The Mycobacterium tuberculosis protein kinase K modulates activation of transcription from the promoter of mycobacterial monooxygenase operon through phosphorylation of the transcriptional regulator VirS","volume":"284","author":"Kumar","year":"2009","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.meegid.2016.07.004_bb0070","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/j.jsbmb.2006.12.059","article-title":"Steps towards flexible docking: modeling of three-dimensional structures of the nuclear receptors bound with peptide ligands mimicking co-activators' sequences","volume":"103","author":"Kurcinski","year":"2007","journal-title":"J. Steroid Biochem. Mol. Biol."},{"key":"10.1016\/j.meegid.2016.07.004_bb0075","doi-asserted-by":"crossref","first-page":"1397","DOI":"10.1093\/bioinformatics\/btn128","article-title":"Accurate approximation method for prediction of class I MHC affinities for peptides of length 8, 10 and 11 using prediction tools trained on 9mers","volume":"24","author":"Lundegaard","year":"2008","journal-title":"Bioinformatics"},{"key":"10.1016\/j.meegid.2016.07.004_bb0080","doi-asserted-by":"crossref","first-page":"W445","DOI":"10.1093\/nar\/gkq311","article-title":"HexServer: an FFT-based protein docking server powered by graphics processors","volume":"38","author":"Macindoe","year":"2010","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.meegid.2016.07.004_bb0085","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1017\/S1462399403005957","article-title":"MHC-based vaccination approaches: progress and perspectives","volume":"5","author":"Mehra","year":"2003","journal-title":"Expert Rev. Mol. Med."},{"key":"10.1016\/j.meegid.2016.07.004_bb0090","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1110\/ps.0239403","article-title":"Reliable prediction of T-cell epitopes using neural networks with novel sequence representations","volume":"12","author":"Nielsen","year":"2003","journal-title":"Protein Sci."},{"key":"10.1016\/j.meegid.2016.07.004_bb0095","doi-asserted-by":"crossref","first-page":"1388","DOI":"10.1093\/bioinformatics\/bth100","article-title":"Improved prediction of MHC class I and class II epitopes using a novel Gibbs sampling approach","volume":"20","author":"Nielsen","year":"2004","journal-title":"Bioinformatics"},{"key":"10.1016\/j.meegid.2016.07.004_bb0100","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.ijmyco.2015.10.005","article-title":"Analysis of the DosR regulon genes to select cytotoxic T lymphocyte epitope specific vaccine candidates using a reverse vaccinology approach","volume":"5","author":"Pandey","year":"2015","journal-title":"Int. J. Mycobacteriol."},{"key":"10.1016\/j.meegid.2016.07.004_bb0105","doi-asserted-by":"crossref","first-page":"163","DOI":"10.4049\/jimmunol.152.1.163","article-title":"Scheme for ranking potential HLA-A2 binding peptides based on independent binding of individual peptide side-chains","volume":"152","author":"Parker","year":"1994","journal-title":"J. Immunol."},{"key":"10.1016\/j.meegid.2016.07.004_bb0110","doi-asserted-by":"crossref","first-page":"180","DOI":"10.3389\/fimmu.2014.00180","article-title":"Functional signatures of human CD4 and CD8 T cell responses to Mycobacterium tuberculosis","volume":"5","author":"Prezzemolo","year":"2014","journal-title":"Front. Immunol."},{"key":"10.1016\/j.meegid.2016.07.004_bb0115","first-page":"213","article-title":"Immunology of tuberculosis","volume":"120","author":"Raja","year":"2004","journal-title":"Indian J. Med. Res."},{"key":"10.1016\/j.meegid.2016.07.004_bb0120","doi-asserted-by":"crossref","first-page":"1361","DOI":"10.1038\/nbt1207-1361","article-title":"Bridging the knowledge gaps in vaccine design","volume":"25","author":"Rappuoli","year":"2007","journal-title":"Nat. Biotechnol."},{"key":"10.1016\/j.meegid.2016.07.004_bb0125","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/j.ijmyco.2014.06.006","article-title":"Cell wall-associated Mycobacterium tuberculosis rRv3083 protein stimulates macrophages through toll-like receptor-2 (TLR2)","volume":"4","author":"Saraav","year":"2014","journal-title":"Int. J. Mycobacteriol."},{"key":"10.1016\/j.meegid.2016.07.004_bb0130","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1038\/icb.2014.52","article-title":"Outcome of Mycobacterium tuberculosis and toll-like receptor interaction: immune response or immune evasion?","volume":"92","author":"Saraav","year":"2014","journal-title":"Immunol. Cell Biol."},{"key":"10.1016\/j.meegid.2016.07.004_bb0135","doi-asserted-by":"crossref","first-page":"1236","DOI":"10.1093\/bioinformatics\/17.12.1236","article-title":"ProPred: prediction of HLA-DR binding sites","volume":"17","author":"Singh","year":"2001","journal-title":"Bioinformatics"},{"key":"10.1016\/j.meegid.2016.07.004_bb0140","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/S0378-1097(03)00648-7","article-title":"mymA operon of Mycobacterium tuberculosis: its regulation and importance in the cell envelope","volume":"227","author":"Singh","year":"2003","journal-title":"FEMS Microbiol. Lett."},{"key":"10.1016\/j.meegid.2016.07.004_bb0145","doi-asserted-by":"crossref","first-page":"4173","DOI":"10.1128\/JB.187.12.4173-4186.2005","article-title":"Requirement of the mymA operon for appropriate cell wall ultrastructure and persistence of Mycobacterium tuberculosis in the spleens of Guinea pigs","volume":"187","author":"Singh","year":"2005","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.meegid.2016.07.004_bb0150","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1016\/j.vaccine.2013.11.065","article-title":"Immunogenic potential of latency associated antigens against Mycobacterium tuberculosis","volume":"32","author":"Singh","year":"2014","journal-title":"Vaccine"},{"key":"10.1016\/j.meegid.2016.07.004_bb0155","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1016\/S0140-6736(13)60177-4","article-title":"Safety and efficacy of MVA85A, a new tuberculosis vaccine, in infants previously vaccinated with BCG: a randomised, placebo-controlled phase 2b trial","volume":"381","author":"Tameris","year":"2013","journal-title":"Lancet"},{"key":"10.1016\/j.meegid.2016.07.004_bb0160","doi-asserted-by":"crossref","first-page":"1068","DOI":"10.4049\/jimmunol.1002212","article-title":"Genome-based in silico identification of new Mycobacterium tuberculosis antigens activating polyfunctional CD8+ T cells in human tuberculosis","volume":"186","author":"Tang","year":"2010","journal-title":"J. Immunol."},{"key":"10.1016\/j.meegid.2016.07.004_bb0165","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1016\/j.micinf.2005.09.012","article-title":"A combined immuno-informatics and structure-based modeling approach for prediction of T cell epitopes of secretory proteins of Mycobacterium tuberculosis","volume":"8","author":"Vani","year":"2006","journal-title":"Microbes Infect."},{"key":"10.1016\/j.meegid.2016.07.004_bb0170","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1093\/nar\/gku938","article-title":"The immune epitope database (IEDB) 3.0.","volume":"43","author":"Vita","year":"2015","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.meegid.2016.07.004_bb0175","doi-asserted-by":"crossref","first-page":"5816","DOI":"10.1021\/pr1005873","article-title":"Proteomic definition of the cell wall of Mycobacterium tuberculosis","volume":"9","author":"Wolfe","year":"2010","journal-title":"J. Proteome Res."},{"key":"10.1016\/j.meegid.2016.07.004_bb0180","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1615\/CritRevImmunol.v26.i4.30","article-title":"Mycobacterium tuberculosis-specific CD8+ T cells and their role in immunity","volume":"26","author":"Woodworth","year":"2006","journal-title":"Crit. Rev. Immunol."}],"container-title":["Infection, Genetics and Evolution"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567134816302829?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567134816302829?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,8,19]],"date-time":"2023-08-19T03:35:56Z","timestamp":1692416156000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1567134816302829"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,10]]},"references-count":36,"alternative-id":["S1567134816302829"],"URL":"https:\/\/doi.org\/10.1016\/j.meegid.2016.07.004","relation":{},"ISSN":["1567-1348"],"issn-type":[{"type":"print","value":"1567-1348"}],"subject":[],"published":{"date-parts":[[2016,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Predicting promiscuous antigenic T cell epitopes of Mycobacterium tuberculosis mymA operon proteins binding to MHC Class I and Class II molecules","name":"articletitle","label":"Article Title"},{"value":"Infection, Genetics and Evolution","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.meegid.2016.07.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}